메뉴 건너뛰기




Volumn 194, Issue , 2009, Pages 451-491

The role of peptides in central sensitization

Author keywords

Calcitonin gene related peptide; Creb; Hyperalgesia; Inflammation; Neurokinin; Nfat; Receptor; Spinal cord; Substance p

Indexed keywords

ADRENOMEDULLIN; AMPA RECEPTOR; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN RECEPTOR LIKE RECEPTOR; CYCLIC AMP; GLUTAMIC ACID; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROKININ 1 RECEPTOR; NEUROKININ 2 RECEPTOR; NEUROKININ 2 RECEPTOR ANTAGONIST; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR AGONIST; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PEPTIDE; PHOSPHOLIPASE C; PROSTAGLANDIN; PROTEIN KINASE C INHIBITOR; SUBSTANCE P; TACHYKININ RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFAT; LIGAND;

EID: 70349934573     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-540-79090-7_13     Document Type: Review
Times cited : (179)

References (224)
  • 1
    • 0026614009 scopus 로고
    • Autoradiographic analysis of 125I-substance P binding in rat spinal cord following chronic constriction injury of the sciatic nerve
    • Aanonsen LM, Kajander KC, Bennett GJ, Seybold VS (1992) Autoradiographic analysis of 125I-substance P binding in rat spinal cord following chronic constriction injury of the sciatic nerve. Brain Res 596:259-268
    • (1992) Brain Res , vol.596 , pp. 259-268
    • Aanonsen, L.M.1    Kajander, K.C.2    Bennett, G.J.3    Seybold, V.S.4
  • 2
    • 0029655582 scopus 로고    scopus 로고
    • Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain
    • Abbadie C, Brown JL, Mantyh PW, Basbaum AI (1996) Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience 70:201-209
    • (1996) Neuroscience , vol.70 , pp. 201-209
    • Abbadie, C.1    Brown, J.L.2    Mantyh, P.W.3    Basbaum, A.I.4
  • 3
    • 0030798999 scopus 로고    scopus 로고
    • Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation
    • Abbadie C, Trafton J, Liu H, Mantyh PW, Basbaum AI (1997) Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. J Neurosci 17:8049-8060
    • (1997) J Neurosci , vol.17 , pp. 8049-8060
    • Abbadie, C.1    Trafton, J.2    Liu, H.3    Mantyh, P.W.4    Basbaum, A.I.5
  • 4
    • 0033027202 scopus 로고    scopus 로고
    • Cyclic AMP regulates the expression of neurokinin1 receptors by neonatal rat spinal neurons in culture
    • Abrahams LG, Reutter MA, McCarson KE, Seybold VS (1999) Cyclic AMP regulates the expression of neurokinin1 receptors by neonatal rat spinal neurons in culture. J Neurochem 73:50-58
    • (1999) J Neurochem , vol.73 , pp. 50-58
    • Abrahams, L.G.1    Reutter, M.A.2    McCarson, K.E.3    Seybold, V.S.4
  • 5
    • 34848848681 scopus 로고    scopus 로고
    • Spinal CGRP1 receptors contribute to supraspinally organized pain behavior and pain-related sensitization of amygdala neurons
    • Adwanikar H, Ji G, Li W, Doods H, Willis WD, Neugebauer V (2007) Spinal CGRP1 receptors contribute to supraspinally organized pain behavior and pain-related sensitization of amygdala neurons. Pain 132:53-66
    • (2007) Pain , vol.132 , pp. 53-66
    • Adwanikar, H.1    Ji, G.2    Li, W.3    Doods, H.4    Willis, W.D.5    Neugebauer, V.6
  • 6
    • 33744827973 scopus 로고    scopus 로고
    • Volume transmission and wiring transmission from cellular to molecular networks: History and perspectives
    • Agnati LF, Leo G, Zanardi A, Genedani S, Rivera A, Fuxe K, Guidolin D (2006) Volume transmission and wiring transmission from cellular to molecular networks: history and perspectives. Acta Physiol 187:329-344
    • (2006) Acta Physiol , vol.187 , pp. 329-344
    • Agnati, L.F.1    Leo, G.2    Zanardi, A.3    Genedani, S.4    Rivera, A.5    Fuxe, K.6    Guidolin, D.7
  • 7
    • 0028325094 scopus 로고
    • Permeation of proteins from the blood into peripheral nerves and ganglia
    • Allen DT, Kiernan JA (1994) Permeation of proteins from the blood into peripheral nerves and ganglia. Neuroscience 59:755-764
    • (1994) Neuroscience , vol.59 , pp. 755-764
    • Allen, D.T.1    Kiernan, J.A.2
  • 8
  • 9
    • 0019948176 scopus 로고
    • Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products
    • Amara SG, Jonas V, Rosenfeld MG, Ong ES, Evans RM (1982) Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature 298:240-244
    • (1982) Nature , vol.298 , pp. 240-244
    • Amara, S.G.1    Jonas, V.2    Rosenfeld, M.G.3    Ong, E.S.4    Evans, R.M.5
  • 10
    • 0021857460 scopus 로고
    • Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin generelated peptide
    • Amara SG, Arriza JL, Leff SE, Swanson LW, Evans RM, Rosenfeld MG (1985) Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin generelated peptide. Science 229:1094-1097
    • (1985) Science , vol.229 , pp. 1094-1097
    • Amara, S.G.1    Arriza, J.L.2    Leff, S.E.3    Swanson, L.W.4    Evans, R.M.5    Rosenfeld, M.G.6
  • 11
    • 0029999313 scopus 로고    scopus 로고
    • Chemically mediated cross-excitation in rat dorsal root ganglia
    • Amir R, Devor M (1996) Chemically mediated cross-excitation in rat dorsal root ganglia. J Neurosci 16:4733-4741
    • (1996) J Neurosci , vol.16 , pp. 4733-4741
    • Amir, R.1    Devor, M.2
  • 12
    • 0034737689 scopus 로고    scopus 로고
    • Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception
    • Anderson LE, Seybold VS (2000) Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception. Neurosci Lett 283:29-32
    • (2000) Neurosci Lett , vol.283 , pp. 29-32
    • Anderson, L.E.1    Seybold, V.S.2
  • 13
    • 10644231738 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide regulates gene transcription in primary afferent neurons
    • Anderson LE, Seybold VS (2004) Calcitonin gene-related peptide regulates gene transcription in primary afferent neurons. J Neurochem 91:1417-1429
    • (2004) J Neurochem , vol.91 , pp. 1417-1429
    • Anderson, L.E.1    Seybold, V.S.2
  • 14
    • 0027387032 scopus 로고
    • Effect of bradykinin and prostaglandins on the release of calcitonin gene-related peptide-like immunoreactivity from the rat spinal cord in vitro
    • Andreeva L, Rang HP (1993) Effect of bradykinin and prostaglandins on the release of calcitonin gene-related peptide-like immunoreactivity from the rat spinal cord in vitro. Br J Pharmacol 108:185-190
    • (1993) Br J Pharmacol , vol.108 , pp. 185-190
    • Andreeva, L.1    Rang, H.P.2
  • 15
    • 0032439786 scopus 로고    scopus 로고
    • Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis
    • Beiche F, Brune K, Geisslinger G, Goppelt-Struebe M (1998) Expression of cyclooxygenase isoforms in the rat spinal cord and their regulation during adjuvant-induced arthritis. Inflamm Res 47:482-487
    • (1998) Inflamm Res , vol.47 , pp. 482-487
    • Beiche, F.1    Brune, K.2    Geisslinger, G.3    Goppelt-Struebe, M.4
  • 18
    • 0028120848 scopus 로고
    • Subpopulations of neonatal rat sensory neurons express functional neurotransmitter receptors which elevate intracellular calcium
    • Bowie D, Feltz P, Schlichter R (1994) Subpopulations of neonatal rat sensory neurons express functional neurotransmitter receptors which elevate intracellular calcium. Neuroscience 58:141-149
    • (1994) Neuroscience , vol.58 , pp. 141-149
    • Bowie, D.1    Feltz, P.2    Schlichter, R.3
  • 19
    • 0031915846 scopus 로고    scopus 로고
    • A role for L-type calcium channels in developmental regulation of transmitter phenotype in primary sensory neurons
    • Brosenitsch TA, Salgado-Commissariat D, Kunze DL, Katz DM (1998) A role for L-type calcium channels in developmental regulation of transmitter phenotype in primary sensory neurons. J Neurosci 18:1047-1055
    • (1998) J Neurosci , vol.18 , pp. 1047-1055
    • Brosenitsch, T.A.1    Salgado-Commissariat, D.2    Kunze, D.L.3    Katz, D.M.4
  • 20
    • 0028999428 scopus 로고
    • Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis
    • Brown JL, Liu H, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI (1995) Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. J Comp Neurol 356:327-344
    • (1995) J Comp Neurol , vol.356 , pp. 327-344
    • Brown, J.L.1    Liu, H.2    Maggio, J.E.3    Vigna, S.R.4    Mantyh, P.W.5    Basbaum, A.I.6
  • 23
    • 0030599130 scopus 로고    scopus 로고
    • Localization and activation of substance P receptors in unmyelinated axons of rat glabrous skin
    • Carlton SM, Zhou S, Coggeshall RE (1996) Localization and activation of substance P receptors in unmyelinated axons of rat glabrous skin. Brain Res 734:103-108
    • (1996) Brain Res , vol.734 , pp. 103-108
    • Carlton, S.M.1    Zhou, S.2    Coggeshall, R.E.3
  • 24
    • 0034683198 scopus 로고    scopus 로고
    • Activation of transcription factors of nuclear factor kappa B, activator protein-1 and octamer factors in hyperalgesia
    • Chan CF, Sun WZ, Lin JK, Lin-Shiau SY (2000) Activation of transcription factors of nuclear factor kappa B, activator protein-1 and octamer factors in hyperalgesia. Eur J Pharmacol 402:61-68
    • (2000) Eur J Pharmacol , vol.402 , pp. 61-68
    • Chan, C.F.1    Sun, W.Z.2    Lin, J.K.3    Lin-Shiau, S.Y.4
  • 25
    • 0026768917 scopus 로고
    • The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat
    • Chapman V, Dickenson AH (1992) The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat. Eur J Pharmacol 219:427-433
    • (1992) Eur J Pharmacol , vol.219 , pp. 427-433
    • Chapman, V.1    Dickenson, A.H.2
  • 26
    • 0021908773 scopus 로고
    • Characterization and segmental distribution of 125I-Bolton-Hunterlabeled substance P binding sites in rat spinal cord
    • Charlton CG, Helke CJ (1985) Characterization and segmental distribution of 125I-Bolton-Hunterlabeled substance P binding sites in rat spinal cord. J Neurosci 5:1293-1299
    • (1985) J Neurosci , vol.5 , pp. 1293-1299
    • Charlton, C.G.1    Helke, C.J.2
  • 27
    • 0026552808 scopus 로고
    • Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation
    • Chen L, Huang LY (1992) Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation. Nature 356:521-523
    • (1992) Nature , vol.356 , pp. 521-523
    • Chen, L.1    Huang, L.Y.2
  • 28
    • 0025999839 scopus 로고
    • Central neural mediators of secondary hyperalgesia following heat injury in rats: Neuropeptides and excitatory amino acids
    • Coderre TJ, Melzack R (1991) Central neural mediators of secondary hyperalgesia following heat injury in rats: neuropeptides and excitatory amino acids. Neurosci Lett 131:71-74
    • (1991) Neurosci Lett , vol.131 , pp. 71-74
    • Coderre, T.J.1    Melzack, R.2
  • 29
    • 0023157121 scopus 로고
    • Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input
    • Cook AJ, Woolf CJ, Wall PD, McMahon SB (1987) Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input. Nature 325:151-153
    • (1987) Nature , vol.325 , pp. 151-153
    • Cook, A.J.1    Woolf, C.J.2    Wall, P.D.3    McMahon, S.B.4
  • 30
    • 0023794552 scopus 로고
    • Facilitation of the tail-flick reflex by noxious cutaneous stimulation in the rat: Antagonism by a substance P analogue
    • Cridland RA, Henry JL (1988) Facilitation of the tail-flick reflex by noxious cutaneous stimulation in the rat: antagonism by a substance P analogue. Brain Res 462:15-21
    • (1988) Brain Res , vol.462 , pp. 15-21
    • Cridland, R.A.1    Henry, J.L.2
  • 31
    • 0029161130 scopus 로고
    • Modulation of excitatory amino acid responses by tachykinins and selective tachykinin receptor agonists in the rat spinal cord
    • Cumberbatch MJ, Chizh BA, Headley PM (1995) Modulation of excitatory amino acid responses by tachykinins and selective tachykinin receptor agonists in the rat spinal cord. Br J Pharmacol 115:1005-1012
    • (1995) Br J Pharmacol , vol.115 , pp. 1005-1012
    • Cumberbatch, M.J.1    Chizh, B.A.2    Headley, P.M.3
  • 33
    • 0026735237 scopus 로고
    • Spinal neurons exhibiting a specific nociceptive response receive abundant substance P-containing synaptic contacts
    • De Koninck Y, Ribeiro-da-Silva A, Henry JL, Cuello AC (1992) Spinal neurons exhibiting a specific nociceptive response receive abundant substance P-containing synaptic contacts. Proc Natl Acad Sci USA 89: 5073-5077
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5073-5077
    • De Koninck, Y.1    Ribeiro-Da-Silva, A.2    Henry, J.L.3    Cuello, A.C.4
  • 35
    • 0037219982 scopus 로고    scopus 로고
    • Transient up-regulation of spinal cyclooxygenase-2 and neuronal nitric oxide synthase following surgical inflammation
    • Dolan S, Kelly JG, HuanM, NolanAM(2003) Transient up-regulation of spinal cyclooxygenase-2 and neuronal nitric oxide synthase following surgical inflammation. Anesthesiology 98:170-180
    • (2003) Anesthesiology , vol.98 , pp. 170-180
    • Dolan, S.1    Kelly, J.G.2    Nolanam, H.3
  • 36
    • 0026459977 scopus 로고
    • Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis in the rat
    • Donaldson LF, Harmar AJ, McQueen DS, Seckl JR (1992) Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis in the rat. Molec Brain Res 16:143-149
    • (1992) Molec Brain Res , vol.16 , pp. 143-149
    • Donaldson, L.F.1    Harmar, A.J.2    McQueen, D.S.3    Seckl, J.R.4
  • 37
    • 0026045337 scopus 로고
    • Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of N-methyl-Daspartic acid and substance P
    • Dougherty PM, Willis WD (1991) Enhancement of spinothalamic neuron responses to chemical and mechanical stimuli following combined micro-iontophoretic application of N-methyl-Daspartic acid and substance P. Pain 47:85-93
    • (1991) Pain , vol.47 , pp. 85-93
    • Dougherty, P.M.1    Willis, W.D.2
  • 38
    • 0028113246 scopus 로고
    • Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin
    • Dougherty PM, Palecek J, Paleckova V, Willis WD (1994) Neurokinin 1 and 2 antagonists attenuate the responses and NK1 antagonists prevent the sensitization of primate spinothalamic tract neurons after intradermal capsaicin. J Neurophysiol 72:1464-1475
    • (1994) J Neurophysiol , vol.72 , pp. 1464-1475
    • Dougherty, P.M.1    Palecek, J.2    Paleckova, V.3    Willis, W.D.4
  • 39
    • 0023950602 scopus 로고
    • Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat
    • Duggan AW, Hendry IA, Morton CR, Hutchison WD, Zhao ZQ (1988) Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat. Brain Res 451:261-273
    • (1988) Brain Res , vol.451 , pp. 261-273
    • Duggan, A.W.1    Hendry, I.A.2    Morton, C.R.3    Hutchison, W.D.4    Zhao, Z.Q.5
  • 40
    • 0025348422 scopus 로고
    • Release, spread and persistence of immunoreactive neurokinin A in the dorsal horn of the cat following noxious cutaneous stimulation. Studies with antibody microprobes
    • Duggan AW, Hope PJ, Jarrott B, Schaible HG, Fleetwood-Walker SM (1990) Release, spread and persistence of immunoreactive neurokinin A in the dorsal horn of the cat following noxious cutaneous stimulation. Studies with antibody microprobes. Neuroscience 35:195-202
    • (1990) Neuroscience , vol.35 , pp. 195-202
    • Duggan, A.W.1    Hope, P.J.2    Jarrott, B.3    Schaible, H.G.4    Fleetwood-Walker, S.M.5
  • 41
    • 0028968596 scopus 로고
    • Afferent volley patterns and the spinal release of immunoreactive substance P in the dorsal horn of the anaesthetized spinal cat
    • Duggan AW, Riley RC, Mark MA, MacMillan SJ, Schaible HG (1995) Afferent volley patterns and the spinal release of immunoreactive substance P in the dorsal horn of the anaesthetized spinal cat. Neuroscience 65:849-858
    • (1995) Neuroscience , vol.65 , pp. 849-858
    • Duggan, A.W.1    Riley, R.C.2    Mark, M.A.3    MacMillan, S.J.4    Schaible, H.G.5
  • 42
    • 5044250210 scopus 로고    scopus 로고
    • CGRP receptor antagonists: A new choice for acute treatment of migraine?
    • Durham PL (2004) CGRP receptor antagonists: a new choice for acute treatment of migraine? Curr Opin Investig Drugs 5:731-735
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 731-735
    • Durham, P.L.1
  • 43
    • 17744373464 scopus 로고    scopus 로고
    • Clinical data on the CGRP antagonist BIBN4096BS for treatment of migraine attacks
    • Edvinsson L (2005) Clinical data on the CGRP antagonist BIBN4096BS for treatment of migraine attacks. CNS Drug Rev 11:69-76
    • (2005) CNS Drug Rev , vol.11 , pp. 69-76
    • Edvinsson, L.1
  • 44
    • 0030792234 scopus 로고    scopus 로고
    • Expression of calcitonin gene-related peptide1 receptor mRNA in human trigeminal ganglia and cerebral arteries
    • Edvinsson L, Cantera L, Jansen-Olesen I, Uddman R (1997) Expression of calcitonin gene-related peptide1 receptor mRNA in human trigeminal ganglia and cerebral arteries. Neurosci Lett 229:209-211
    • (1997) Neurosci Lett , vol.229 , pp. 209-211
    • Edvinsson, L.1    Cantera, L.2    Jansen-Olesen, I.3    Uddman, R.4
  • 45
    • 0037312605 scopus 로고    scopus 로고
    • PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity
    • Esteban JA, Shi SH, Wilson C, Nuriya M, Huganir RL, Malinow R (2003) PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nat Neurosci 6:136-143
    • (2003) Nat Neurosci , vol.6 , pp. 136-143
    • Esteban, J.A.1    Shi, S.H.2    Wilson, C.3    Nuriya, M.4    Huganir, R.L.5    Malinow, R.6
  • 46
    • 0034613266 scopus 로고    scopus 로고
    • CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors
    • Evans BN, Rosenblatt MI, Mnayer LO, Oliver KR, Dickerson IM (2000) CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors. J Biol Chem 275:31438-31443
    • (2000) J Biol Chem , vol.275 , pp. 31438-31443
    • Evans, B.N.1    Rosenblatt, M.I.2    Mnayer, L.O.3    Oliver, K.R.4    Dickerson, I.M.5
  • 47
    • 0037095759 scopus 로고    scopus 로고
    • Calcium-calmodulin-dependent protein kinase II contributes to spinal cord central sensitization
    • Fang L, Wu J, Lin Q, Willis WD (2002) Calcium-calmodulin-dependent protein kinase II contributes to spinal cord central sensitization. J Neurosci 22:4196-4204
    • (2002) J Neurosci , vol.22 , pp. 4196-4204
    • Fang, L.1    Wu, J.2    Lin, Q.3    Willis, W.D.4
  • 48
    • 0030766928 scopus 로고    scopus 로고
    • Action potential-dependent regulation of gene expression: Temporal specificity in Ca2+, cAMP-responsive element binding proteins, and mitogen-activated protein kinase signaling
    • Fields RD, Eshete F, Stevens B, Itoh K (1997) Action potential-dependent regulation of gene expression: temporal specificity in Ca2+, cAMP-responsive element binding proteins, and mitogen-activated protein kinase signaling. J Neurosci 17:7252-7266
    • (1997) J Neurosci , vol.17 , pp. 7252-7266
    • Fields, R.D.1    Eshete, F.2    Stevens, B.3    Itoh, K.4
  • 49
    • 0025369202 scopus 로고
    • The involvement of neurokinin receptor subtypes in somatosensory processing in the superficial dorsal horn of the cat
    • Erratum in: Brain Res (1992) 579: 357
    • Fleetwood-Walker SM, Mitchell R, Hope PJ, El-Yassir N, Molony V, Bladon CM (1990) The involvement of neurokinin receptor subtypes in somatosensory processing in the superficial dorsal horn of the cat. Brain Res 519:169-182. Erratum in: Brain Res (1992) 579:357
    • (1990) Brain Res , vol.519 , pp. 169-182
    • Fleetwood-Walker, S.M.1    Mitchell, R.2    Hope, P.J.3    El-Yassir, N.4    Molony, V.5    Bladon, C.M.6
  • 50
    • 0025870042 scopus 로고
    • Islet amyloid polypeptide (IAPP) competes for two binding sites of CGRP
    • Galeazza MT, O'Brien TD, Johnson KH, Seybold VS (1991) Islet amyloid polypeptide (IAPP) competes for two binding sites of CGRP. Peptides 12:585-1491
    • (1991) Peptides , vol.12 , pp. 585-1491
    • Galeazza, M.T.1    O'Brien, T.D.2    Johnson, K.H.3    Seybold, V.S.4
  • 51
    • 0026616801 scopus 로고
    • Changes in [125I]hCGRP binding in rat spinal cord in an experimental model of acute, peripheral inflammation
    • Galeazza MT, Stucky CL, Seybold VS (1992) Changes in [125I]hCGRP binding in rat spinal cord in an experimental model of acute, peripheral inflammation. Brain Res 591:198-208
    • (1992) Brain Res , vol.591 , pp. 198-208
    • Galeazza, M.T.1    Stucky, C.L.2    Seybold, V.S.3
  • 52
    • 0028969303 scopus 로고
    • Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation
    • Galeazza MT, Garry MG, Yost HJ, Strait KA, Hargreaves KM, Seybold VS (1995) Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation. Neuroscience 66:443-458
    • (1995) Neuroscience , vol.66 , pp. 443-458
    • Galeazza, M.T.1    Garry, M.G.2    Yost, H.J.3    Strait, K.A.4    Hargreaves, K.M.5    Seybold, V.S.6
  • 53
    • 0022501437 scopus 로고
    • Nociceptive behavior after intrathecal injections of substance P, neurokinin A and calcitonin gene-related peptide in mice
    • Gamse R, Saria A (1986) Nociceptive behavior after intrathecal injections of substance P, neurokinin A and calcitonin gene-related peptide in mice. Neurosci Lett 70:143-147
    • (1986) Neurosci Lett , vol.70 , pp. 143-147
    • Gamse, R.1    Saria, A.2
  • 54
    • 0026637909 scopus 로고
    • Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation
    • Garry MG, Hargreaves KM (1992) Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation. Brain Res 582:139-142
    • (1992) Brain Res , vol.582 , pp. 139-142
    • Garry, M.G.1    Hargreaves, K.M.2
  • 55
    • 0024379442 scopus 로고
    • Lumbar dorsal root ganglia of the cat: A quantitative study of peptide immunoreactivity and cell size
    • Garry MG, Miller KE, Seybold VS (1989) Lumbar dorsal root ganglia of the cat: a quantitative study of peptide immunoreactivity and cell size. J Comp Neurol 284:36-47
    • (1989) J Comp Neurol , vol.284 , pp. 36-47
    • Garry, M.G.1    Miller, K.E.2    Seybold, V.S.3
  • 56
    • 0026331697 scopus 로고
    • Human substance P receptor (NK-1): Organization of the gene, chromosome localization, and functional expression of cDNA clones
    • Gerard NP, Garraway LA, Eddy RL Jr, Shows TB, Iijima H, Paquet JL, Gerard C (1991) Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones. Biochemistry 30:10640-10646
    • (1991) Biochemistry , vol.30 , pp. 10640-10646
    • Gerard, N.P.1    Garraway, L.A.2    Eddy Jr., R.L.3    Shows, T.B.4    Iijima, H.5    Paquet, J.L.6    Gerard, C.7
  • 57
    • 0024415219 scopus 로고
    • Multiple effects of phorbol esters in the rat spinal dorsal horn
    • Gerber G, Kangrga I, Ryu PD, Larew JS, RandicM(1989) Multiple effects of phorbol esters in the rat spinal dorsal horn. J Neurosci 9:3606-3617
    • (1989) J Neurosci , vol.9 , pp. 3606-3617
    • Gerber, G.1    Kangrga, I.2    Ryu, P.D.3    Larew, J.S.4    Randic, M.5
  • 60
    • 0041835836 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor activation of NFAT (nuclear factor of activated T cells)-dependent transcription: A role for the transcription factor NFATc4 in neurotrophin-mediated gene expression
    • Groth RD, Mermelstein PG (2003) Brain-derived neurotrophic factor activation of NFAT (nuclear factor of activated T cells)-dependent transcription: a role for the transcription factor NFATc4 in neurotrophin-mediated gene expression. J Neurosci 23:8125-8134
    • (2003) J Neurosci , vol.23 , pp. 8125-8134
    • Groth, R.D.1    Mermelstein, P.G.2
  • 61
    • 34547177480 scopus 로고    scopus 로고
    • Neurotrophin activation of NFATdependent transcription contributes to the regulation of pro-nociceptive genes
    • Groth RD, Coicou LG, Mermelstein PG, Seybold VS (2007) Neurotrophin activation of NFATdependent transcription contributes to the regulation of pro-nociceptive genes. J Neurochem 102:1162-1174
    • (2007) J Neurochem , vol.102 , pp. 1162-1174
    • Groth, R.D.1    Coicou, L.G.2    Mermelstein, P.G.3    Seybold, V.S.4
  • 62
    • 33847213470 scopus 로고    scopus 로고
    • The colocalization of CGRP receptor and AMPA receptor in the spinal dorsal horn neuron of rat: A morphological and electrophysiological study
    • Gu XL, Yu LC (2007) The colocalization of CGRP receptor and AMPA receptor in the spinal dorsal horn neuron of rat: a morphological and electrophysiological study. Neurosci Lett 414:237-241
    • (2007) Neurosci Lett , vol.414 , pp. 237-241
    • Gu, X.L.1    Yu, L.C.2
  • 63
    • 0037101627 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia
    • Guo W, Zou S, Guan Y, Ikeda T, Tal M, Dubner R, Ren K (2002) Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia. J Neurosci 22:6208-6217
    • (2002) J Neurosci , vol.22 , pp. 6208-6217
    • Guo, W.1    Zou, S.2    Guan, Y.3    Ikeda, T.4    Tal, M.5    Dubner, R.6    Ren, K.7
  • 64
    • 0017181611 scopus 로고
    • Effects of substance P on functionally identified units in cat spinal cord
    • Henry JL (1976) Effects of substance P on functionally identified units in cat spinal cord. Brain Res 114:439-451
    • (1976) Brain Res , vol.114 , pp. 439-451
    • Henry, J.L.1
  • 65
    • 0025761856 scopus 로고
    • Organization, structure and expression of the gene encoding the rat substance P receptor
    • Hershey AD, Dykema PE, Krause JE (1991) Organization, structure and expression of the gene encoding the rat substance P receptor. J Biol Chem 266:4366-4374
    • (1991) J Biol Chem , vol.266 , pp. 4366-4374
    • Hershey, A.D.1    Dykema, P.E.2    Krause, J.E.3
  • 66
    • 0034214841 scopus 로고    scopus 로고
    • NK1 substance P receptor antagonists - Why are they not analgesic in humans?
    • Hill R (2000) NK1 (substance P) receptor antagonists - why are they not analgesic in humans? Trends Pharmacol Sci 21:244-246
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 244-246
    • Hill, R.1
  • 67
    • 0006982482 scopus 로고
    • Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: Enkephalin and substance P
    • Hökfelt T, Ljungdahl A, Terenius L, Elde R, Nilsson G (1977) Immunohistochemical analysis of peptide pathways possibly related to pain and analgesia: enkephalin and substance P. Proc Natl Acad Sci USA 74:3081-3085
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 3081-3085
    • Hökfelt, T.1    Ljungdahl, A.2    Terenius, L.3    Elde, R.4    Nilsson, G.5
  • 68
    • 0033197997 scopus 로고    scopus 로고
    • Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states
    • Honore P, Menning PM, Rogers SD, Nichols ML, Basbaum AI, Besson JM, Mantyh PW (1999) Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states. J Neurosci 19:7670-7678
    • (1999) J Neurosci , vol.19 , pp. 7670-7678
    • Honore, P.1    Menning, P.M.2    Rogers, S.D.3    Nichols, M.L.4    Basbaum, A.I.5    Besson, J.M.6    Mantyh, P.W.7
  • 69
    • 0033103611 scopus 로고    scopus 로고
    • Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acids
    • Hua XY, Chen P, Marsala M, Yaksh TL (1999) Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acids. Neuroscience 89:525-534
    • (1999) Neuroscience , vol.89 , pp. 525-534
    • Hua, X.Y.1    Chen, P.2    Marsala, M.3    Yaksh, T.L.4
  • 70
    • 0019360303 scopus 로고
    • An immunohistochemical study of neuronal populations containing neuropeptides or gamma-aminobutyrate within the superficial layers of the rat dorsal horn
    • Hunt SP, Kelly JS, Emson PC, Kimmel JR, Miller RJ, Wu JY (1981) An immunohistochemical study of neuronal populations containing neuropeptides or gamma-aminobutyrate within the superficial layers of the rat dorsal horn. Neuroscience 6:1883-1898
    • (1981) Neuroscience , vol.6 , pp. 1883-1898
    • Hunt, S.P.1    Kelly, J.S.2    Emson, P.C.3    Kimmel, J.R.4    Miller, R.J.5    Wu, J.Y.6
  • 71
    • 0023277535 scopus 로고
    • Induction of c-fos-like protein in spinal cord neurons following sensory stimulation
    • Hunt SP, Pini A, Evan G (1987) Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 328:632-634
    • (1987) Nature , vol.328 , pp. 632-634
    • Hunt, S.P.1    Pini, A.2    Evan, G.3
  • 72
    • 0024381828 scopus 로고
    • Expansion of receptive fields of spinal lamina i projection neurons in rats with unilateral adjuvant-induced inflammation: The contribution of dorsal horn mechanisms
    • Hylden JL, Nahin RL, Traub RJ, Dubner R (1989) Expansion of receptive fields of spinal lamina I projection neurons in rats with unilateral adjuvant-induced inflammation: the contribution of dorsal horn mechanisms. Pain 37:229-243
    • (1989) Pain , vol.37 , pp. 229-243
    • Hylden, J.L.1    Nahin, R.L.2    Traub, R.J.3    Dubner, R.4
  • 73
    • 0024268743 scopus 로고
    • Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: Stimulus specificity, behavioral parameters and opioid receptor binding
    • Iadarola MJ, Brady LS, Draisci G, Dubner R (1988) Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding. Pain 35:313-326
    • (1988) Pain , vol.35 , pp. 313-326
    • Iadarola, M.J.1    Brady, L.S.2    Draisci, G.3    Dubner, R.4
  • 74
    • 0022459299 scopus 로고
    • Autoradiographic localization of calcitonin gene-related peptide binding sites in human and rat brains
    • Inagaki S, Kito S, Kubota Y, Girgis S, Hillyard CJ, MacIntyre I (1986) Autoradiographic localization of calcitonin gene-related peptide binding sites in human and rat brains. Brain Res 374:287-298
    • (1986) Brain Res , vol.374 , pp. 287-298
    • Inagaki, S.1    Kito, S.2    Kubota, Y.3    Girgis, S.4    Hillyard, C.J.5    MacIntyre, I.6
  • 75
    • 0028951781 scopus 로고
    • Nonselective cation channels coupled with tachykinin receptors in rat sensory neurons
    • Inoue K, Nakazawa K, Inoue K, Fujimori K (1995) Nonselective cation channels coupled with tachykinin receptors in rat sensory neurons. J Neurophysiol 73:736-742
    • (1995) J Neurophysiol , vol.73 , pp. 736-742
    • Inoue, K.1    Nakazawa, K.2    Inoue, K.3    Fujimori, K.4
  • 76
    • 0031460066 scopus 로고    scopus 로고
    • Intrathecal administration of a new nitric oxide donor, NOC-18, produces acute thermal hyperalgesia in the rat
    • Inoue T, Mashimo T, Shibuta S, Yoshiya I (1997) Intrathecal administration of a new nitric oxide donor, NOC-18, produces acute thermal hyperalgesia in the rat. J Neurol Sci 153:1-7
    • (1997) J Neurol Sci , vol.153 , pp. 1-7
    • Inoue, T.1    Mashimo, T.2    Shibuta, S.3    Yoshiya, I.4
  • 77
    • 0031054038 scopus 로고    scopus 로고
    • Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: Relationship to c-fos induction
    • Ji RR, Rupp F (1997) Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction. J Neurosci 17:1776-1785
    • (1997) J Neurosci , vol.17 , pp. 1776-1785
    • Ji, R.R.1    Rupp, F.2
  • 78
    • 0033490464 scopus 로고    scopus 로고
    • Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity
    • Ji RR, Baba H, Brenner GJ, Woolf CJ (1999) Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity. Nat Neurosci 2:1114-1119
    • (1999) Nat Neurosci , vol.2 , pp. 1114-1119
    • Ji, R.R.1    Baba, H.2    Brenner, G.J.3    Woolf, C.J.4
  • 79
    • 0242475309 scopus 로고    scopus 로고
    • Central sensitization and LTP: Do pain and memory share similar mechanisms?
    • Ji RR, Kohno T, Moore KA, Woolf CJ (2003) Central sensitization and LTP: do pain and memory share similar mechanisms? Trends Neuro Sci 26:696-705
    • (2003) Trends Neuro Sci , vol.26 , pp. 696-705
    • Ji, R.R.1    Kohno, T.2    Moore, K.A.3    Woolf, C.J.4
  • 80
    • 0030612063 scopus 로고    scopus 로고
    • Spinal NK2 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation
    • Jia YP, Seybold VS (1997) Spinal NK2 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation. Brain Res 751:169-174
    • (1997) Brain Res , vol.751 , pp. 169-174
    • Jia, Y.P.1    Seybold, V.S.2
  • 81
    • 0019360302 scopus 로고
    • Immunohistochemical support for three putative transmitters in one neuron: Coexistence of 5-hydroxytryptamine, substance P- and thyrotropin releasing hormone-like immunoreactivity in medullary neurons projecting to the spinal cord
    • Johansson O, Hokfelt T, Pernow B, Jeffcoate SL, White N, Steinbusch HW, Verhofstad AA, Emson PC, Spindel E (1981) Immunohistochemical support for three putative transmitters in one neuron: coexistence of 5-hydroxytryptamine, substance P- and thyrotropin releasing hormone-like immunoreactivity in medullary neurons projecting to the spinal cord. Neuroscience 6:1857-1881
    • (1981) Neuroscience , vol.6 , pp. 1857-1881
    • Johansson, O.1    Hokfelt, T.2    Pernow, B.3    Jeffcoate, S.L.4    White, N.5    Steinbusch, H.W.6    Verhofstad, A.A.7    Emson, P.C.8    Spindel, E.9
  • 82
    • 0034327470 scopus 로고    scopus 로고
    • The molecular pharmacology of CGRP and related peptide receptor subtypes
    • Juaneda C, Dumont Y, Quirion R (2000) The molecular pharmacology of CGRP and related peptide receptor subtypes. Trends Pharmacol Sci 21:432-438
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 432-438
    • Juaneda, C.1    Dumont, Y.2    Quirion, R.3
  • 83
    • 0026520456 scopus 로고
    • Intrathecal injection of acetylsalicylic acid, salicylic acid and indomethacin depresses C fibre-evoked activity in the rat thalamus and spinal cord
    • Jurna I, Spohrer B, Bock R (1992) Intrathecal injection of acetylsalicylic acid, salicylic acid and indomethacin depresses C fibre-evoked activity in the rat thalamus and spinal cord. Pain 49:249-256
    • (1992) Pain , vol.49 , pp. 249-256
    • Jurna, I.1    Spohrer, B.2    Bock, R.3
  • 84
    • 0025441936 scopus 로고
    • Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice
    • Kangrga I, Randic M (1990) Tachykinins and calcitonin gene-related peptide enhance release of endogenous glutamate and aspartate from the rat spinal dorsal horn slice. J Neurosci 10:2026-2038
    • (1990) J Neurosci , vol.10 , pp. 2026-2038
    • Kangrga, I.1    Randic, M.2
  • 85
    • 0026440476 scopus 로고
    • Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P
    • Kessler W, Kirchhoff C, Reeh PW, Handwerker HO (1992) Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P. Exp Brain Res 91:467-476
    • (1992) Exp Brain Res , vol.91 , pp. 467-476
    • Kessler, W.1    Kirchhoff, C.2    Reeh, P.W.3    Handwerker, H.O.4
  • 86
    • 0037109674 scopus 로고    scopus 로고
    • Spinal neurons that possess the substance P receptor are required for the development of central sensitization
    • Khasabov SG, Rogers SD, Ghilardi JR, Peters CM, Mantyh PW, Simone DA (2002) Spinal neurons that possess the substance P receptor are required for the development of central sensitization. J Neurosci 22:9086-9098
    • (2002) J Neurosci , vol.22 , pp. 9086-9098
    • Khasabov, S.G.1    Rogers, S.D.2    Ghilardi, J.R.3    Peters, C.M.4    Mantyh, P.W.5    Simone, D.A.6
  • 87
    • 0026739958 scopus 로고
    • Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse
    • Kitto KF, Haley JE, Wilcox GL (1992) Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse. Neurosci Lett 148:1-5
    • (1992) Neurosci Lett , vol.148 , pp. 1-5
    • Kitto, K.F.1    Haley, J.E.2    Wilcox, G.L.3
  • 89
    • 0031013146 scopus 로고    scopus 로고
    • Functional expression of a novel human neurokinin-3 receptor homolog that binds [3H]senktide and [125I-MePhe7]neurokinin B, and is responsive to tachykinin peptide agonists
    • Krause JE, Staveteig PT, Mentzer JN, Schmidt SK, Tucker JB, Brodbeck RM, Bu JY, Karpitskiy VV (1997) Functional expression of a novel human neurokinin-3 receptor homolog that binds [3H]senktide and [125I-MePhe7]neurokinin B, and is responsive to tachykinin peptide agonists. Proc Natl Acad Sci USA 94:310-315
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 310-315
    • Krause, J.E.1    Staveteig, P.T.2    Mentzer, J.N.3    Schmidt, S.K.4    Tucker, J.B.5    Brodbeck, R.M.6    Bu, J.Y.7    Karpitskiy, V.V.8
  • 90
    • 0023715267 scopus 로고
    • Calcitonin gene-related peptide (CGRP) in the rat central nervous system: Patterns of immunoreactivity and receptor binding sites
    • Kruger L, Mantyh PW, Sternini C, Brecha NC, Mantyh CR (1988) Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites. Brain Res 463:223-244
    • (1988) Brain Res , vol.463 , pp. 223-244
    • Kruger, L.1    Mantyh, P.W.2    Sternini, C.3    Brecha, N.C.4    Mantyh, C.R.5
  • 91
    • 0035310531 scopus 로고    scopus 로고
    • Gut feelings about tachykinins NK1 receptor antagonists
    • Laird J (2001) Gut feelings about tachykinins NK1 receptor antagonists. Trends Pharmacol Sci 22:169
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 169
    • Laird, J.1
  • 92
    • 0027175055 scopus 로고
    • Effect of RP 67580, a non-peptide neurokinin1 receptor antagonist, on facilitation of a nociceptive spinal flexion reflex in the rat
    • Laird JM, Hargreaves RJ, Hill RG (1993) Effect of RP 67580, a non-peptide neurokinin1 receptor antagonist, on facilitation of a nociceptive spinal flexion reflex in the rat. Br J Pharmacol 109:713-718
    • (1993) Br J Pharmacol , vol.109 , pp. 713-718
    • Laird, J.M.1    Hargreaves, R.J.2    Hill, R.G.3
  • 93
    • 0030009063 scopus 로고    scopus 로고
    • Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw
    • Lam HH, Hanley DF, Trapp BD, Saito S, Raja S, Dawson TM, Yamaguchi H (1996) Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw. Neurosci Lett 210:201-204
    • (1996) Neurosci Lett , vol.210 , pp. 201-204
    • Lam, H.H.1    Hanley, D.F.2    Trapp, B.D.3    Saito, S.4    Raja, S.5    Dawson, T.M.6    Yamaguchi, H.7
  • 94
    • 0023895888 scopus 로고
    • Desensitization to intrathecal substance P in mice: Possible involvement of opioids
    • Larson AA (1988) Desensitization to intrathecal substance P in mice: possible involvement of opioids. Pain 32:367-374
    • (1988) Pain , vol.32 , pp. 367-374
    • Larson, A.A.1
  • 95
    • 0025851154 scopus 로고
    • The action of calcitonin gene-related peptide on astrocyte morphology and cyclic AMP accumulation in astrocyte cultures from neonatal rat brain
    • Lazar P, Reddington M, Streit W, Raivich G, Kreutzberg GW (1991) The action of calcitonin gene-related peptide on astrocyte morphology and cyclic AMP accumulation in astrocyte cultures from neonatal rat brain. Neurosci Lett 130:99-102
    • (1991) Neurosci Lett , vol.130 , pp. 99-102
    • Lazar, P.1    Reddington, M.2    Streit, W.3    Raivich, G.4    Kreutzberg, G.W.5
  • 96
    • 0022347682 scopus 로고
    • Calcitonin gene-related peptide is a potent inhibitor of substance P degradation
    • Le Greves P, Nyberg F, Terenius L, Hokfelt T (1985) Calcitonin gene-related peptide is a potent inhibitor of substance P degradation. Eur J Pharmacol 115:309-311
    • (1985) Eur J Pharmacol , vol.115 , pp. 309-311
    • Le Greves, P.1    Nyberg, F.2    Terenius, L.3    Hokfelt, T.4
  • 97
    • 34447282998 scopus 로고    scopus 로고
    • Involvement of substance P and calcitonin gene-related peptide in development and maintenance of neuropathic pain from spinal nerve injury model of rat
    • Lee SE, Kim JH (2007) Involvement of substance P and calcitonin gene-related peptide in development and maintenance of neuropathic pain from spinal nerve injury model of rat. Neurosci Res 58:245-249
    • (2007) Neurosci Res , vol.58 , pp. 245-249
    • Lee, S.E.1    Kim, J.H.2
  • 98
    • 0242628124 scopus 로고    scopus 로고
    • Basal and activityinduced release of substance P from primary afferent fibres in NK1 receptor knockout mice: Evidence for negative feedback
    • Lever IJ, Grant AD, Pezet S, Gerard NP, Brain SD, Malcangio M (2003) Basal and activityinduced release of substance P from primary afferent fibres in NK1 receptor knockout mice: evidence for negative feedback. Neuropharmacology 45:1101-1110
    • (2003) Neuropharmacology , vol.45 , pp. 1101-1110
    • Lever, I.J.1    Grant, A.D.2    Pezet, S.3    Gerard, N.P.4    Brain, S.D.5    Malcangio, M.6
  • 99
    • 0031848890 scopus 로고    scopus 로고
    • Small sensory neurons in the rat dorsal root ganglia express functional NK-1 tachykinin receptor
    • Li HS, Zhao ZQ (1998) Small sensory neurons in the rat dorsal root ganglia express functional NK-1 tachykinin receptor. Eur J Neurosci 10:1292-1299
    • (1998) Eur J Neurosci , vol.10 , pp. 1292-1299
    • Li, H.S.1    Zhao, Z.Q.2
  • 100
    • 0018770078 scopus 로고
    • Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers
    • Light AR, Perl ER (1979) Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers. J Comp Neurol 186:133-150
    • (1979) J Comp Neurol , vol.186 , pp. 133-150
    • Light, A.R.1    Perl, E.R.2
  • 101
    • 0032588157 scopus 로고    scopus 로고
    • Spinal neurokinin3 receptors mediate thermal but not mechanical hyperalgesia via nitric oxide
    • Linden DR, Seybold VS (1999) Spinal neurokinin3 receptors mediate thermal but not mechanical hyperalgesia via nitric oxide. Pain 80:309-317
    • (1999) Pain , vol.80 , pp. 309-317
    • Linden, D.R.1    Seybold, V.S.2
  • 102
    • 0032588155 scopus 로고    scopus 로고
    • Spinal neurokin3 receptors facilitate the nociceptive flexor reflex via a pathway involving nitric oxide
    • Linden DR, Jia YP, Seybold VS (1999) Spinal neurokin3 receptors facilitate the nociceptive flexor reflex via a pathway involving nitric oxide. Pain 80:301-308
    • (1999) Pain , vol.80 , pp. 301-308
    • Linden, D.R.1    Jia, Y.P.2    Seybold, V.S.3
  • 103
    • 0034012342 scopus 로고    scopus 로고
    • Neurokinin(3) receptors couple to the activation of neuronal nitric-oxide synthase in stably transfected Chinese hamster ovary cells
    • Linden DR, Chell MJ, El-Fakahany EE, Seybold VS (2000a) Neurokinin(3) receptors couple to the activation of neuronal nitric-oxide synthase in stably transfected Chinese hamster ovary cells. J Pharmacol Exp Ther 293:559-568
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 559-568
    • Linden, D.R.1    Chell, M.J.2    El-Fakahany, E.E.3    Seybold, V.S.4
  • 104
    • 0034049751 scopus 로고    scopus 로고
    • Time-dependent changes in neurokinin(3) receptors and tachykinins during adjuvant-induced peripheral inflammation in the rat
    • Linden DR, Reutter MA, McCarson KE, Seybold VS (2000b) Time-dependent changes in neurokinin(3) receptors and tachykinins during adjuvant-induced peripheral inflammation in the rat. Neuroscience 98:801-811
    • (2000) Neuroscience , vol.98 , pp. 801-811
    • Linden, D.R.1    Reutter, M.A.2    McCarson, K.E.3    Seybold, V.S.4
  • 105
    • 1842372050 scopus 로고    scopus 로고
    • Characterization of long-term potentiation of C-fiber-evoked potentials in spinal dorsal horn of adult rat: Essential role of NK1 and NK2 receptors
    • Liu X, Sandkuhler J (1997) Characterization of long-term potentiation of C-fiber-evoked potentials in spinal dorsal horn of adult rat: essential role of NK1 and NK2 receptors. J Neurophysiol 78:1973-1982
    • (1997) J Neurophysiol , vol.78 , pp. 1973-1982
    • Liu, X.1    Sandkuhler, J.2
  • 106
    • 0028091385 scopus 로고
    • Synaptic relationship between substance P and the substance P receptor: Light and electron microscopic characterization of the mismatch between neuropeptides and their receptors
    • Liu H, Brown JL, Jasmin L, Maggio JE, Vigna SR, Mantyh PW, Basbaum AI (1994) Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proc Natl Acad Sci USA 91:1009-1013
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1009-1013
    • Liu, H.1    Brown, J.L.2    Jasmin, L.3    Maggio, J.E.4    Vigna, S.R.5    Mantyh, P.W.6    Basbaum, A.I.7
  • 107
    • 0024598704 scopus 로고
    • Cell type and conduction velocity of rat primary sensory neurons with substance P-like immunoreactivity
    • McCarthy PW, Lawson SN (1989) Cell type and conduction velocity of rat primary sensory neurons with substance P-like immunoreactivity. Neuroscience 28:745-753
    • (1989) Neuroscience , vol.28 , pp. 745-753
    • McCarthy, P.W.1    Lawson, S.N.2
  • 108
    • 0025261124 scopus 로고
    • Cell type and conduction velocity of rat primary sensory neurons with calcitonin gene-related peptide-like immunoreactivity
    • McCarthy PW, Lawson SN (1990) Cell type and conduction velocity of rat primary sensory neurons with calcitonin gene-related peptide-like immunoreactivity. Neuroscience 34:623-632
    • (1990) Neuroscience , vol.34 , pp. 623-632
    • McCarthy, P.W.1    Lawson, S.N.2
  • 110
    • 0028306448 scopus 로고
    • Spinal mediators of hyperalgesia
    • Meller ST, Gebhart GF (1994) Spinal mediators of hyperalgesia. Drugs 47:10-20
    • (1994) Drugs , vol.47 , pp. 10-20
    • Meller, S.T.1    Gebhart, G.F.2
  • 111
    • 0034004905 scopus 로고    scopus 로고
    • Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials
    • Mermelstein PG, Bito H, Deisseroth K, Tsien RW (2000) Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials. J Neurosci 20:266-273
    • (2000) J Neurosci , vol.20 , pp. 266-273
    • Mermelstein, P.G.1    Bito, H.2    Deisseroth, K.3    Tsien, R.W.4
  • 112
    • 0031613751 scopus 로고    scopus 로고
    • Transcription factor regulation of prodynorphin gene expression following rat hindpaw inflammation
    • Messersmith DJ, Kim DJ, Iadarola MJ (1998) Transcription factor regulation of prodynorphin gene expression following rat hindpaw inflammation. Mol Brain Res 53:260-269
    • (1998) Mol Brain Res , vol.53 , pp. 260-269
    • Messersmith, D.J.1    Kim, D.J.2    Iadarola, M.J.3
  • 113
    • 0036804410 scopus 로고    scopus 로고
    • Increases in the phosphorylation of cyclic AMP response element binding protein (CREB) and decreases in the content of calcineurin accompany thermal hyperalgesia following chronic constriction injury in rats
    • Miletic G, Pankratz MT, Miletic V (2002) Increases in the phosphorylation of cyclic AMP response element binding protein (CREB) and decreases in the content of calcineurin accompany thermal hyperalgesia following chronic constriction injury in rats. Pain 99:493-500
    • (2002) Pain , vol.99 , pp. 493-500
    • Miletic, G.1    Pankratz, M.T.2    Miletic, V.3
  • 114
    • 0028362407 scopus 로고
    • Involvement of glutamate receptors in allodynia induced by prostaglandins E2 and F2 alpha injected into conscious mice
    • Minami T, Nishihara I, Uda R, Ito S, Hyodo M, Hayaishi O (1994a) Involvement of glutamate receptors in allodynia induced by prostaglandins E2 and F2 alpha injected into conscious mice. Pain 57:225-231
    • (1994) Pain , vol.57 , pp. 225-231
    • Minami, T.1    Nishihara, I.2    Uda, R.3    Ito, S.4    Hyodo, M.5    Hayaishi, O.6
  • 115
    • 0028363557 scopus 로고
    • Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice
    • Minami T, Uda R, Horiguchi S, Ito S, Hyodo M, Hayaishi O (1994b) Allodynia evoked by intrathecal administration of prostaglandin E2 to conscious mice. Pain 57:217-223
    • (1994) Pain , vol.57 , pp. 217-223
    • Minami, T.1    Uda, R.2    Horiguchi, S.3    Ito, S.4    Hyodo, M.5    Hayaishi, O.6
  • 116
    • 0021277125 scopus 로고
    • Hyperalgesia produced by intrathecal substance P and related peptides: Desensitization and cross desensitization
    • Moochhala SM, Sawynok J (1984) Hyperalgesia produced by intrathecal substance P and related peptides: desensitization and cross desensitization. Br J Pharmacol 82:381-388
    • (1984) Br J Pharmacol , vol.82 , pp. 381-388
    • Moochhala, S.M.1    Sawynok, J.2
  • 117
    • 0033496863 scopus 로고    scopus 로고
    • Functional calcitonin gene-related peptide type 1 and adrenomedullin receptors in human trigeminal ganglia, brain vessels, and cerebromicrovascular or astroglial cells in culture
    • Moreno MJ, Cohen Z, Stanimirovic DB, Hamel E (1999) Functional calcitonin gene-related peptide type 1 and adrenomedullin receptors in human trigeminal ganglia, brain vessels, and cerebromicrovascular or astroglial cells in culture. J Cereb Blood Flow Metab 19:1270-1278
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1270-1278
    • Moreno, M.J.1    Cohen, Z.2    Stanimirovic, D.B.3    Hamel, E.4
  • 118
    • 0036173268 scopus 로고    scopus 로고
    • Characterization of calcitonin gene-related peptide (CGRP) receptors and their receptor-activity-modifying proteins (RAMPs) in human brain microvascular and astroglial cells in culture
    • Moreno MJ, Terron JA, Stanimirovic DB, Doods H, Hamel E (2002) Characterization of calcitonin gene-related peptide (CGRP) receptors and their receptor-activity-modifying proteins (RAMPs) in human brain microvascular and astroglial cells in culture. Neuropharmacology 42:270-280
    • (2002) Neuropharmacology , vol.42 , pp. 270-280
    • Moreno, M.J.1    Terron, J.A.2    Stanimirovic, D.B.3    Doods, H.4    Hamel, E.5
  • 119
    • 0026419327 scopus 로고
    • Molecular cloning and characterization of the rat NMDA receptor
    • Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S (1991) Molecular cloning and characterization of the rat NMDA receptor. Nature 354:31-37 (Pubitemid 21896774)
    • (1991) Nature , vol.354 , Issue.6348 , pp. 31-37
    • Moriyoshi, K.1    Masu, M.2    Ishii, T.3    Shigemoto, R.4    Mizuno, N.5    Nakanishi, S.6
  • 121
    • 0024829811 scopus 로고
    • Release of sensory neuropeptides in the spinal cord: Studies with calcitonin gene-related peptide and galanin
    • Morton CR, Hutchison WD (1989) Release of sensory neuropeptides in the spinal cord: studies with calcitonin gene-related peptide and galanin. Neuroscience 31:807-815
    • (1989) Neuroscience , vol.31 , pp. 807-815
    • Morton, C.R.1    Hutchison, W.D.2
  • 123
    • 0027435390 scopus 로고
    • The effects of neurokinin receptor antagonists on mustard oil-evoked activation of rat dorsal horn neurons
    • Munro FE, Fleetwood-Walker SM, Parker RM, Mitchell R (1993) The effects of neurokinin receptor antagonists on mustard oil-evoked activation of rat dorsal horn neurons. Neuropeptides 25:299-305
    • (1993) Neuropeptides , vol.25 , pp. 299-305
    • Munro, F.E.1    Fleetwood-Walker, S.M.2    Parker, R.M.3    Mitchell, R.4
  • 124
    • 0024348163 scopus 로고
    • Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons
    • DOI 10.1016/0304-3940(89)90485-0
    • Murase K, Ryu PD, Randic M (1989) Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons. Neurosci Lett 103:56-63 (Pubitemid 19207482)
    • (1989) Neuroscience Letters , vol.103 , Issue.1 , pp. 56-63
    • Murase, K.1    Ryu, P.D.2    Randic, M.3
  • 125
    • 0026795882 scopus 로고
    • Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells
    • Nakajima Y, Tsuchida K, Negishi M, Ito S, Nakanishi S (1992) Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells. J Biol Chem. 267:2437-2442
    • (1992) J Biol Chem. , vol.267 , pp. 2437-2442
    • Nakajima, Y.1    Tsuchida, K.2    Negishi, M.3    Ito, S.4    Nakanishi, S.5
  • 126
    • 0025326779 scopus 로고
    • Evidence for a central component in the sensitization of spinal neurons with joint input during development of acute arthritis in cat's knee
    • Neugebauer V, Schaible HG (1990) Evidence for a central component in the sensitization of spinal neurons with joint input during development of acute arthritis in cat's knee. J Neurophysiol 64:299-311
    • (1990) J Neurophysiol , vol.64 , pp. 299-311
    • Neugebauer, V.1    Schaible, H.G.2
  • 127
    • 0030061488 scopus 로고    scopus 로고
    • The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat
    • Neugebauer V, Rumenapp P, Schaible HG (1996) The role of spinal neurokinin-2 receptors in the processing of nociceptive information from the joint and in the generation and maintenance of inflammation-evoked hyperexcitability of dorsal horn neurons in the rat. Eur J Neurosci 8:249-260
    • (1996) Eur J Neurosci , vol.8 , pp. 249-260
    • Neugebauer, V.1    Rumenapp, P.2    Schaible, H.G.3
  • 128
    • 0025008869 scopus 로고
    • Co-expression of alpha-CGRP and beta-CGRP mRNAs in the rat dorsal root ganglion cells
    • Noguchi K, Senba E, Morita Y, Sato M, Tohyama M (1990) Co-expression of alpha-CGRP and beta-CGRP mRNAs in the rat dorsal root ganglion cells. Neurosci Lett 108:1-5
    • (1990) Neurosci Lett , vol.108 , pp. 1-5
    • Noguchi, K.1    Senba, E.2    Morita, Y.3    Sato, M.4    Tohyama, M.5
  • 129
    • 0024387848 scopus 로고
    • Differences in the chemical expression of rat primary afferent neurons which innervate skin, muscle or joint
    • O'Brien C, Woolf CJ, Fitzgerald M, Lindsay RM, Molander C (1989) Differences in the chemical expression of rat primary afferent neurons which innervate skin, muscle or joint. Neuroscience 32:493-502
    • (1989) Neuroscience , vol.32 , pp. 493-502
    • O'Brien, C.1    Woolf, C.J.2    Fitzgerald, M.3    Lindsay, R.M.4    Molander, C.5
  • 130
    • 0022381305 scopus 로고
    • Regional distribution of substance P, neurokinin alpha and neurokinin beta in rat spinal cord, nerve roots and dorsal root ganglia, and the effects of dorsal root section or spinal transection
    • Ogawa T, Kanazawa I, Kimura S (1985) Regional distribution of substance P, neurokinin alpha and neurokinin beta in rat spinal cord, nerve roots and dorsal root ganglia, and the effects of dorsal root section or spinal transection. Brain Res 359:152-157
    • (1985) Brain Res , vol.359 , pp. 152-157
    • Ogawa, T.1    Kanazawa, I.2    Kimura, S.3
  • 131
    • 0023143665 scopus 로고
    • Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats
    • Oku R, Satoh M, Fujii N, Otaka A, Yajima H, Takagi H (1987) Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats. Brain Res 403:350-354
    • (1987) Brain Res , vol.403 , pp. 350-354
    • Oku, R.1    Satoh, M.2    Fujii, N.3    Otaka, A.4    Yajima, H.5    Takagi, H.6
  • 134
    • 0033994508 scopus 로고    scopus 로고
    • The role of nitric oxide and prostaglandin E2 on the hyperalgesia induced by excitatory amino acids in rats
    • Park YH, Shin CY, Lee TS, Huh IH, Sohn UD (2000) The role of nitric oxide and prostaglandin E2 on the hyperalgesia induced by excitatory amino acids in rats. J Pharm Pharmacol 52:431-436
    • (2000) J Pharm Pharmacol , vol.52 , pp. 431-436
    • Park, Y.H.1    Shin, C.Y.2    Lee, T.S.3    Huh, I.H.4    Sohn, U.D.5
  • 135
    • 0030950788 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide induces the formation of second messengers in primary cultures of neonatal rat spinal cord
    • Parsons AM, Seybold VS (1997) Calcitonin gene-related peptide induces the formation of second messengers in primary cultures of neonatal rat spinal cord. Synapse 26:235-242
    • (1997) Synapse , vol.26 , pp. 235-242
    • Parsons, A.M.1    Seybold, V.S.2
  • 136
    • 0029068642 scopus 로고
    • Tachykinins alter inositol phosphate formation, but not cyclic AMP levels, in primary cultures of neonatal rat spinal neurons through activation of neurokinin receptors
    • Parsons AM, el-Fakahany EE, Seybold VS (1995) Tachykinins alter inositol phosphate formation, but not cyclic AMP levels, in primary cultures of neonatal rat spinal neurons through activation of neurokinin receptors. Neuroscience 68:855-865
    • (1995) Neuroscience , vol.68 , pp. 855-865
    • Parsons, A.M.1    El-Fakahany, E.E.2    Seybold, V.S.3
  • 137
    • 0030580166 scopus 로고    scopus 로고
    • Spinal NK1 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation
    • Parsons AM, Honda CN, Jia YP, Budai D, Xu XJ, Wiesenfeld-Hallin Z, Seybold VS (1996) Spinal NK1 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation. Brain Res 739:263-275
    • (1996) Brain Res , vol.739 , pp. 263-275
    • Parsons, A.M.1    Honda, C.N.2    Jia, Y.P.3    Budai, D.4    Xu, X.J.5    Wiesenfeld-Hallin, Z.6    Seybold, V.S.7
  • 138
    • 0031971830 scopus 로고    scopus 로고
    • Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves
    • Perry MJ, Lawson SN (1998) Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves. Neuroscience 85:293-310
    • (1998) Neuroscience , vol.85 , pp. 293-310
    • Perry, M.J.1    Lawson, S.N.2
  • 139
    • 0027405487 scopus 로고
    • Use of non-peptide tachykinin receptor antagonists to substantiate the involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the rat
    • Picard P, Boucher S, Regoli D, Gitter BD, Howbert JJ, Couture R (1993) Use of non-peptide tachykinin receptor antagonists to substantiate the involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the rat. Eur J Pharmacol 232:255-261
    • (1993) Eur J Pharmacol , vol.232 , pp. 255-261
    • Picard, P.1    Boucher, S.2    Regoli, D.3    Gitter, B.D.4    Howbert, J.J.5    Couture, R.6
  • 140
    • 0032780671 scopus 로고    scopus 로고
    • Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: Results with indomethacin in the rat in vivo
    • Pitcher GM, Henry JL (1999) Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: results with indomethacin in the rat in vivo. Neuroscience 93:1109-1121
    • (1999) Neuroscience , vol.93 , pp. 1109-1121
    • Pitcher, G.M.1    Henry, J.L.2
  • 141
    • 0035370602 scopus 로고    scopus 로고
    • Meloxicam selectively depresses the afterdischarge of rat spinal dorsal horn neurones in response to noxious stimulation
    • Pitcher GM, Henry JL (2001) Meloxicam selectively depresses the afterdischarge of rat spinal dorsal horn neurones in response to noxious stimulation. Neurosci Lett 305:45-48
    • (2001) Neurosci Lett , vol.305 , pp. 45-48
    • Pitcher, G.M.1    Henry, J.L.2
  • 142
    • 0036169041 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide-receptor component protein expression in the uterine cervix, lumbosacral spinal cord, and dorsal root ganglia
    • Pokabla MJ, Dickerson IM, Papka RE (2002) Calcitonin gene-related peptide-receptor component protein expression in the uterine cervix, lumbosacral spinal cord, and dorsal root ganglia. Peptides 23:507-514
    • (2002) Peptides , vol.23 , pp. 507-514
    • Pokabla, M.J.1    Dickerson, I.M.2    Papka, R.E.3
  • 143
    • 0028856641 scopus 로고
    • Pharmacology of receptors for calcitonin gene-related peptide and amylin
    • Poyner D (1995) Pharmacology of receptors for calcitonin gene-related peptide and amylin. Trends Pharmacol Sci 16:424-428
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 424-428
    • Poyner, D.1
  • 144
    • 0025115966 scopus 로고
    • Substance P- and calcitonin gene-related peptide-like immunoreactive pericellular baskets in human trigeminal ganglion
    • Quartu M, Floris A, Del Fiacco M (1990) Substance P- and calcitonin gene-related peptide-like immunoreactive pericellular baskets in human trigeminal ganglion. Basic Appl Histochem 34:177-181
    • (1990) Basic Appl Histochem , vol.34 , pp. 177-181
    • Quartu, M.1    Floris, A.2    Del Fiacco, M.3
  • 145
    • 0017408837 scopus 로고
    • Effects of substance P in cat dorsal horn neurons activated by noxious stimuli
    • Randic M, Miletic V (1977) Effects of substance P in cat dorsal horn neurons activated by noxious stimuli. Brain Res 128:164-169
    • (1977) Brain Res , vol.128 , pp. 164-169
    • Randic, M.1    Miletic, V.2
  • 146
    • 0023076227 scopus 로고
    • Slow excitatory transmission in rat spinal dorsal horn and the effects of capsaicin
    • Randic M, Urban L (1987) Slow excitatory transmission in rat spinal dorsal horn and the effects of capsaicin. Acta Physiol Hung 69:375-392
    • (1987) Acta Physiol Hung , vol.69 , pp. 375-392
    • Randic, M.1    Urban, L.2
  • 147
    • 0025103718 scopus 로고
    • Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones
    • DOI 10.1016/0304-3940(90)90122-P
    • Randic M, Hecimovic H, Ryu PD (1990) Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones. Neurosci Lett 117:74-80 (Pubitemid 20284077)
    • (1990) Neuroscience Letters , vol.117 , Issue.1-2 , pp. 74-80
    • Randic, M.1    Hecimovic, H.2    Ryu, P.D.3
  • 148
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NFAT family: Regulation and function
    • Rao A, Luo C, Hogan PG (1997) Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 15:707-747
    • (1997) Annu Rev Immunol , vol.15 , pp. 707-747
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 149
    • 0030031674 scopus 로고    scopus 로고
    • An isobolographic analysis of the effects of N-methyl-Daspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat
    • Ren K, Iadarola MJ, Dubner R (1996) An isobolographic analysis of the effects of N-methyl-Daspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat. Br J Pharmacol 117:196-202
    • (1996) Br J Pharmacol , vol.117 , pp. 196-202
    • Ren, K.1    Iadarola, M.J.2    Dubner, R.3
  • 150
    • 36849030838 scopus 로고    scopus 로고
    • Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Galphaq-coupled receptors
    • Rojas A, Su J, Yang L, Lee M, Cui N, Zhang X, Fountain D, Jiang C (2008) Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Galphaq-coupled receptors. J Cell Physiol 214:84-95
    • (2008) J Cell Physiol , vol.214 , pp. 84-95
    • Rojas, A.1    Su, J.2    Yang, L.3    Lee, M.4    Cui, N.5    Zhang, X.6    Fountain, D.7    Jiang, C.8
  • 152
    • 0038094464 scopus 로고
    • In situ hybridization histochemistry and immunohistochemistry reveal an increase in spinal dynorphin biosynthesis in rat model of peripheral inflammation and hyperalgesia
    • Ruda MA, Iadarola MJ, Cohen LV, Young WS 3rd (1988) In situ hybridization histochemistry and immunohistochemistry reveal an increase in spinal dynorphin biosynthesis in rat model of peripheral inflammation and hyperalgesia. Proc Natl Acad Sci USA 85:622-626
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 622-626
    • Ruda, M.A.1    Iadarola, M.J.2    Cohen, L.V.3    Young Iii, W.S.4
  • 153
    • 0026686412 scopus 로고
    • Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins
    • Rusin KI, Ryu PD, Randic M (1992) Modulation of excitatory amino acid responses in rat dorsal horn neurons by tachykinins. J Neurophysiol 68:265-286
    • (1992) J Neurophysiol , vol.68 , pp. 265-286
    • Rusin, K.I.1    Ryu, P.D.2    Randic, M.3
  • 154
    • 0027464769 scopus 로고
    • Tachykinins potentiate N-methyl-Daspartate responses in acutely isolated neurons from the dorsal horn
    • Rusin KI, Bleakman D, Chard PS, Randic M, Miller RJ (1993) Tachykinins potentiate N-methyl-Daspartate responses in acutely isolated neurons from the dorsal horn. J Neurochem 60: 952-960
    • (1993) J Neurochem , vol.60 , pp. 952-960
    • Rusin, K.I.1    Bleakman, D.2    Chard, P.S.3    Randic, M.4    Miller, R.J.5
  • 155
    • 0023926643 scopus 로고
    • Calcitonin gene-related peptide enhances calcium current of rat dorsal root ganglion neurons and spinal excitatory synaptic transmission
    • Ryu PD, Gerber G, Murase K, Randic M (1988a) Calcitonin gene-related peptide enhances calcium current of rat dorsal root ganglion neurons and spinal excitatory synaptic transmission. Neurosci Lett 89:305-312
    • (1988) Neurosci Lett , vol.89 , pp. 305-312
    • Ryu, P.D.1    Gerber, G.2    Murase, K.3    Randic, M.4
  • 156
    • 0023859087 scopus 로고
    • Actions of calcitonin gene-related peptide on rat spinal dorsal horn neurons
    • Ryu PD, Gerber G, Murase K, Randic M (1988b) Actions of calcitonin gene-related peptide on rat spinal dorsal horn neurons. Brain Res 441:357-361 (Pubitemid 18059984)
    • (1988) Brain Research , vol.441 , Issue.1-2 , pp. 357-361
    • Ryu, P.D.1    Gerber, G.2    Murase, K.3    Randic, M.4
  • 159
    • 0025104302 scopus 로고
    • Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: A study with antibody microprobes
    • Schaible HG, Jarrott B, Hope PJ, Duggan AW (1990) Release of immunoreactive substance P in the spinal cord during development of acute
    • (1990) Brain Res , vol.529 , pp. 214-223
    • Schaible, H.G.1    Jarrott, B.2    Hope, P.J.3    Duggan, A.W.4
  • 160
    • 0026702852 scopus 로고
    • Calcitonin gene-related peptide causes intraspinal spreading of substance P released by peripheral stimulation
    • Schaible HG, Hope PJ, Lang CW, Duggan AW (1992) Calcitonin gene-related peptide causes intraspinal spreading of substance P released by peripheral stimulation. Eur J Neurosci 4:750-757
    • (1992) Eur J Neurosci , vol.4 , pp. 750-757
    • Schaible, H.G.1    Hope, P.J.2    Lang, C.W.3    Duggan, A.W.4
  • 161
    • 0027987920 scopus 로고
    • Intraspinal release of immunoreactive calcitonin gene-related peptide during development of inflammation in the joint in vivo - A study with antibody microprobes in cat and rat
    • Schaible HG, Freudenberger U, Neugebauer V, Stiller RU (1994) Intraspinal release of immunoreactive calcitonin gene-related peptide during development of inflammation in the joint in vivo - a study with antibody microprobes in cat and rat. Neuroscience 62:1293-1305
    • (1994) Neuroscience , vol.62 , pp. 1293-1305
    • Schaible, H.G.1    Freudenberger, U.2    Neugebauer, V.3    Stiller, R.U.4
  • 162
    • 34247278766 scopus 로고    scopus 로고
    • Neurokinins enhance excitability in capsaicin-responsive DRG neurons
    • Sculptoreanu A, de Groat WC (2007) Neurokinins enhance excitability in capsaicin-responsive DRG neurons. Exp Neurol 205:92-100
    • (2007) Exp Neurol , vol.205 , pp. 92-100
    • Sculptoreanu, A.1    De Groat, W.C.2
  • 163
    • 0036499777 scopus 로고    scopus 로고
    • Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons
    • Segond von Banchet G, Pastor A, Biskup C, Schlegel C, Benndorf K, Schaible HG (2002) Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons. Neuroscience 110:131-145
    • (2002) Neuroscience , vol.110 , pp. 131-145
    • Segond Von Banchet, G.1    Pastor, A.2    Biskup, C.3    Schlegel, C.4    Benndorf, K.5    Schaible, H.G.6
  • 165
    • 0028971453 scopus 로고
    • Characterization and regulation of neurokinin1 receptors in primary cultures of rat neonatal spinal neurons
    • Seybold VS, Abrahams LG (1995) Characterization and regulation of neurokinin1 receptors in primary cultures of rat neonatal spinal neurons. Neuroscience 69:1263-1273
    • (1995) Neuroscience , vol.69 , pp. 1263-1273
    • Seybold, V.S.1    Abrahams, L.G.2
  • 166
    • 0018901337 scopus 로고
    • Immunohistochemical studies of peptidergic neurons in the dorsal horn of the spinal cord
    • Seybold V, Elde R (1980) Immunohistochemical studies of peptidergic neurons in the dorsal horn of the spinal cord. J Histochem Cytochem 28:367-370
    • (1980) J Histochem Cytochem , vol.28 , pp. 367-370
    • Seybold, V.1    Elde, R.2
  • 167
    • 0019962093 scopus 로고
    • Intrathecal substance P and somatostatin in rats: Behaviors indicative of sensation
    • Seybold VS, Hylden JLK, Wilcox GL (1982) Intrathecal substance P and somatostatin in rats: Behaviors indicative of sensation. Peptides 3:49-54
    • (1982) Peptides , vol.3 , pp. 49-54
    • Seybold, V.S.1    Hylden, J.L.K.2    Wilcox, G.L.3
  • 169
    • 0141738787 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 contributes to central sensitization in rats with peripheral inflammation
    • Seybold VS, Jia YP, Abrahams LG (2003a) Cyclo-oxygenase-2 contributes to central sensitization in rats with peripheral inflammation. Pain 105:47-55
    • (2003) Pain , vol.105 , pp. 47-55
    • Seybold, V.S.1    Jia, Y.P.2    Abrahams, L.G.3
  • 170
    • 0037337723 scopus 로고    scopus 로고
    • Calcitonin generelated peptide regulates expression of neurokinin1 receptors by rat spinal neurons
    • Seybold VS, McCarson KE, Mermelstein PG, Groth RD, Abrahams LG (2003b) Calcitonin generelated peptide regulates expression of neurokinin1 receptors by rat spinal neurons. J Neurosci 23:1816-1824
    • (2003) J Neurosci , vol.23 , pp. 1816-1824
    • Seybold, V.S.1    McCarson, K.E.2    Mermelstein, P.G.3    Groth, R.D.4    Abrahams, L.G.5
  • 171
    • 33645301584 scopus 로고    scopus 로고
    • Substance P initiates NFAT-dependent gene expression in spinal neurons
    • Seybold VS, Coicou LG, Groth RD, Mermelstein PG (2006) Substance P initiates NFAT-dependent gene expression in spinal neurons. J Neurochem 97:397-407
    • (2006) J Neurochem , vol.97 , pp. 397-407
    • Seybold, V.S.1    Coicou, L.G.2    Groth, R.D.3    Mermelstein, P.G.4
  • 172
    • 0032852479 scopus 로고    scopus 로고
    • CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
    • Shaywitz AJ, Greenberg ME (1999) CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68:821-861
    • (1999) Annu Rev Biochem , vol.68 , pp. 821-861
    • Shaywitz, A.J.1    Greenberg, M.E.2
  • 173
    • 0032055648 scopus 로고    scopus 로고
    • Identification of a signaling pathway involved in calcium regulation of BDNF expression
    • Shieh PB, Hu SC, Bobb K, Timmusk T, Ghosh A (1998) Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron 20:727-740
    • (1998) Neuron , vol.20 , pp. 727-740
    • Shieh, P.B.1    Hu, S.C.2    Bobb, K.3    Timmusk, T.4    Ghosh, A.5
  • 174
    • 0028108484 scopus 로고
    • Structural basis of neuron-to-neuron cross-excitation in dorsal root ganglia
    • Shinder V, Devor M (1994) Structural basis of neuron-to-neuron cross-excitation in dorsal root ganglia. J Neurocytol 23:515-531
    • (1994) J Neurocytol , vol.23 , pp. 515-531
    • Shinder, V.1    Devor, M.2
  • 175
    • 0030890339 scopus 로고    scopus 로고
    • Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation
    • Sluka KA, Milton MA, Willis WD, Westlund KN (1997) Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation. Br J Pharmacol 120:1263-1273
    • (1997) Br J Pharmacol , vol.120 , pp. 1263-1273
    • Sluka, K.A.1    Milton, M.A.2    Willis, W.D.3    Westlund, K.N.4
  • 176
    • 0029952176 scopus 로고    scopus 로고
    • Evoked release of amino acids and prostanoids in spinal cords of anesthetized rats: Changes during peripheral inflammation and hyperalgesia
    • Sorkin LS, Moore JH (1996) Evoked release of amino acids and prostanoids in spinal cords of anesthetized rats: changes during peripheral inflammation and hyperalgesia. Am J Ther 3:268-275
    • (1996) Am J Ther , vol.3 , pp. 268-275
    • Sorkin, L.S.1    Moore, J.H.2
  • 178
    • 17444438461 scopus 로고    scopus 로고
    • Quantitation of neurokinin 1 receptor internalization and recycling in guinea-pig myenteric neurons
    • Southwell BR, Seybold VS, Woodman HL, Jenkinson KM, Furness JB (1998) Quantitation of neurokinin 1 receptor internalization and recycling in guinea-pig myenteric neurons. Neuroscience 87:925-931
    • (1998) Neuroscience , vol.87 , pp. 925-931
    • Southwell, B.R.1    Seybold, V.S.2    Woodman, H.L.3    Jenkinson, K.M.4    Furness, J.B.5
  • 179
    • 0344442742 scopus 로고    scopus 로고
    • A quantitative and morphological study of projection neurons in lamina i of the rat lumbar spinal cord
    • Spike RC, Puskar Z, Andrew D, Todd AJ (2003) A quantitative and morphological study of projection neurons in lamina I of the rat lumbar spinal cord. Eur J Neurosci 18:2433-2448
    • (2003) Eur J Neurosci , vol.18 , pp. 2433-2448
    • Spike, R.C.1    Puskar, Z.2    Andrew, D.3    Todd, A.J.4
  • 180
    • 0029864532 scopus 로고    scopus 로고
    • Localization of the calcium/calmodulin-dependent protein phosphatase, calcineurin, in the hindbrain and spinal cord of the rat
    • Strack S, Wadzinski BE, Ebner FF (1996) Localization of the calcium/calmodulin-dependent protein phosphatase, calcineurin, in the hindbrain and spinal cord of the rat. J Comp Neurol 375:66-76
    • (1996) J Comp Neurol , vol.375 , pp. 66-76
    • Strack, S.1    Wadzinski, B.E.2    Ebner, F.F.3
  • 181
    • 0027366544 scopus 로고
    • Time-dependent changes in Bolton-Hunter-labeled 125I-substance P binding in rat spinal cord following unilateral adjuvant-induced peripheral inflammation
    • Stucky CL, Galeazza MT, Seybold VS (1993) Time-dependent changes in Bolton-Hunter-labeled 125I-substance P binding in rat spinal cord following unilateral adjuvant-induced peripheral inflammation. Neuroscience 57:397-409
    • (1993) Neuroscience , vol.57 , pp. 397-409
    • Stucky, C.L.1    Galeazza, M.T.2    Seybold, V.S.3
  • 182
    • 0022981156 scopus 로고
    • Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin
    • Sugiura Y, Lee CL, Perl ER (1986) Central projections of identified, unmyelinated (C) afferent fibers innervating mammalian skin. Science 234:358-361
    • (1986) Science , vol.234 , pp. 358-361
    • Sugiura, Y.1    Lee, C.L.2    Perl, E.R.3
  • 183
    • 0037823484 scopus 로고    scopus 로고
    • The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin
    • Sun RQ, Lawand NB, Willis WD (2003) The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. Pain 104:201-208
    • (2003) Pain , vol.104 , pp. 201-208
    • Sun, R.Q.1    Lawand, N.B.2    Willis, W.D.3
  • 184
    • 14844293564 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization
    • Sun RQ, Tu YJ, Lawand NB, Yan JY, Lin Q, Willis WD (2004) Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization. J Neurophysiol 92:2859-2866
    • (2004) J Neurophysiol , vol.92 , pp. 2859-2866
    • Sun, R.Q.1    Tu, Y.J.2    Lawand, N.B.3    Yan, J.Y.4    Lin, Q.5    Willis, W.D.6
  • 185
    • 0042267829 scopus 로고    scopus 로고
    • Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia
    • Svensson CI, Hua XY, Protter AA, Powell HC, Yaksh TL (2003) Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia. Neuroreport 14:1153-1157
    • (2003) Neuroreport , vol.14 , pp. 1153-1157
    • Svensson, C.I.1    Hua, X.Y.2    Protter, A.A.3    Powell, H.C.4    Yaksh, T.L.5
  • 186
    • 0022890812 scopus 로고
    • Evidence that substance P may be a modulator rather than a transmitter of noxious mechanical stimulation
    • Sweeney MI, Sawynok J (1986) Evidence that substance P may be a modulator rather than a transmitter of noxious mechanical stimulation. Can J Physiol Pharmacol 64:1324-1327
    • (1986) Can J Physiol Pharmacol , vol.64 , pp. 1324-1327
    • Sweeney, M.I.1    Sawynok, J.2
  • 187
    • 0022541941 scopus 로고
    • Indomethacin blocks central nociceptive effects of PGF2 alpha
    • Taiwo YO, Levine JD (1986) Indomethacin blocks central nociceptive effects of PGF2 alpha. Brain Res 373:81-84
    • (1986) Brain Res , vol.373 , pp. 81-84
    • Taiwo, Y.O.1    Levine, J.D.2
  • 188
    • 0029658415 scopus 로고    scopus 로고
    • Gq/11 and PLC-beta 1 mediate the substance P-induced inhibition of an inward rectifier K+ channel in brain neurons
    • Takano K, Yasufuku-Takano J, Kozasa T, Singer WD, Nakajima S, Nakajima Y (1996) Gq/11 and PLC-beta 1 mediate the substance P-induced inhibition of an inward rectifier K+ channel in brain neurons. J Neurophysiol 76:2131-2136
    • (1996) J Neurophysiol , vol.76 , pp. 2131-2136
    • Takano, K.1    Yasufuku-Takano, J.2    Kozasa, T.3    Singer, W.D.4    Nakajima, S.5    Nakajima, Y.6
  • 189
    • 0026396627 scopus 로고
    • Pharmacological and molecular biological studies on the diversity of rat tachykinin NK-2 receptor subtypes in rat CNS, duodenum, vas deferens, and urinary bladder
    • Takeda Y, Krause JE (1991) Pharmacological and molecular biological studies on the diversity of rat tachykinin NK-2 receptor subtypes in rat CNS, duodenum, vas deferens, and urinary bladder. Ann N Y Acad Sci 632:479-482
    • (1991) Ann N y Acad Sci , vol.632 , pp. 479-482
    • Takeda, Y.1    Krause, J.E.2
  • 190
    • 0026683453 scopus 로고
    • Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in Chinese hamster ovary cells and evidence for differential stimulation of inositol 1,4,5-trisphosphate and cyclic AMP second messenger responses
    • Takeda Y, Blount P, Sachais BS, Hershey AD, Raddatz R, Krause JE (1992) Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in Chinese hamster ovary cells and evidence for differential stimulation of inositol 1,4,5-trisphosphate and cyclic AMP second messenger responses. J Neurochem 59:740-745
    • (1992) J Neurochem , vol.59 , pp. 740-745
    • Takeda, Y.1    Blount, P.2    Sachais, B.S.3    Hershey, A.D.4    Raddatz, R.5    Krause, J.E.6
  • 191
    • 0032034262 scopus 로고    scopus 로고
    • Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism
    • Tao X, Finkbeiner S, Arnold DB, Shaywitz AJ, Greenberg ME (1998) Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron 20:709-726
    • (1998) Neuron , vol.20 , pp. 709-726
    • Tao, X.1    Finkbeiner, S.2    Arnold, D.B.3    Shaywitz, A.J.4    Greenberg, M.E.5
  • 192
    • 0037095729 scopus 로고    scopus 로고
    • Projection neurons in lamina i of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance p-containing afferents and respond to noxious stimulation
    • Todd AJ, Puskar Z, Spike RC, Hughes C, Watt C, Forrest L (2002) Projection neurons in lamina I of rat spinal cord with the neurokinin 1 receptor are selectively innervated by substance p-containing afferents and respond to noxious stimulation. J Neurosci 22:4103-4113
    • (2002) J Neurosci , vol.22 , pp. 4103-4113
    • Todd, A.J.1    Puskar, Z.2    Spike, R.C.3    Hughes, C.4    Watt, C.5    Forrest, L.6
  • 193
    • 0035873496 scopus 로고    scopus 로고
    • Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat
    • Trafton JA, Abbadie C, Basbaum AI (2001) Differential contribution of substance P and neurokinin A to spinal cord neurokinin-1 receptor signaling in the rat. J Neurosci 21:3656-3664
    • (2001) J Neurosci , vol.21 , pp. 3656-3664
    • Trafton, J.A.1    Abbadie, C.2    Basbaum, A.I.3
  • 194
    • 0004954443 scopus 로고
    • Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary
    • Tschopp FA, Tobler PH, Fischer JA (1985) Calcitonin gene-related peptide and its binding sites in the human central nervous system and pituitary. Proc Natl Acad Sci USA 82:248-252
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 248-252
    • Tschopp, F.A.1    Tobler, P.H.2    Fischer, J.A.3
  • 195
    • 0025175645 scopus 로고
    • Tissue distribution and quantitation of the mRNAs for three rat tachykinin receptors
    • Tsuchida K, Shigemoto R, Yokota Y, Nakanishi S (1990) Tissue distribution and quantitation of the mRNAs for three rat tachykinin receptors. Eur J Biochem 193:751-757
    • (1990) Eur J Biochem , vol.193 , pp. 751-757
    • Tsuchida, K.1    Shigemoto, R.2    Yokota, Y.3    Nakanishi, S.4
  • 196
    • 0024581850 scopus 로고
    • A quantitative study of the coexistence of peptides in varicosities within the superficial laminae of the dorsal horn of the rat spinal cord
    • Tuchscherer MM, Seybold VS (1989) A quantitative study of the coexistence of peptides in varicosities within the superficial laminae of the dorsal horn of the rat spinal cord. J Neurosci 9:195-205
    • (1989) J Neurosci , vol.9 , pp. 195-205
    • Tuchscherer, M.M.1    Seybold, V.S.2
  • 197
    • 34249654110 scopus 로고    scopus 로고
    • Antihyperalgesic effect of a recombinant herpes virus encoding antisense for calcitonin gene-related peptide
    • Tzabazis AZ, Pirc G, Votta-Velis E, Wilson SP, Laurito CE, Yeomans DC (2007) Antihyperalgesic effect of a recombinant herpes virus encoding antisense for calcitonin gene-related peptide. Anesthesiology 106:1079-1080
    • (2007) Anesthesiology , vol.106 , pp. 1079-1080
    • Tzabazis, A.Z.1    Pirc, G.2    Votta-Velis, E.3    Wilson, S.P.4    Laurito, C.E.5    Yeomans, D.C.6
  • 198
    • 0025038067 scopus 로고
    • Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2a to conscious mice
    • Uda R, Horiguchi S, Ito S, Hyodo M, Hayaishi O (1990) Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2a to conscious mice. Brain Res 510:26-32
    • (1990) Brain Res , vol.510 , pp. 26-32
    • Uda, R.1    Horiguchi, S.2    Ito, S.3    Hyodo, M.4    Hayaishi, O.5
  • 199
    • 0035085324 scopus 로고    scopus 로고
    • Capsaicinevoked release of immunoreactive calcitonin gene-related peptide from rat trigeminal ganglion: Evidence for intraganglionic neurotransmission
    • Ulrich-Lai YM, Flores CM, Harding-Rose CA, Goodis HE, Hargreaves KM (2001) Capsaicinevoked release of immunoreactive calcitonin gene-related peptide from rat trigeminal ganglion: evidence for intraganglionic neurotransmission. Pain 91:219-226
    • (2001) Pain , vol.91 , pp. 219-226
    • Ulrich-Lai, Y.M.1    Flores, C.M.2    Harding-Rose, C.A.3    Goodis, H.E.4    Hargreaves, K.M.5
  • 200
    • 0034406976 scopus 로고    scopus 로고
    • NK1 receptor antagonists - Are they really without effect in the pain clinic?
    • Urban AL and Fox AJ (2000) NK1 receptor antagonists - are they really without effect in the pain clinic? Trends Pharmacol Sci 12:462-464
    • (2000) Trends Pharmacol Sci , vol.12 , pp. 462-464
    • Urban, A.L.1    Fox, A.J.2
  • 201
    • 0027933184 scopus 로고
    • Modulation of spinal excitability: Co-operation between neurokinin and excitatory amino acid neurotransmitters
    • Urban L, Thompson SWN, Dray A (1994) Modulation of spinal excitability: co-operation between neurokinin and excitatory amino acid neurotransmitters. Trends Neurosci 17:432-438
    • (1994) Trends Neurosci , vol.17 , pp. 432-438
    • Urban, L.1    Thompson, S.W.N.2    Dray, A.3
  • 202
    • 0028169759 scopus 로고
    • Prostaglandin E2 enhances bradykinin-stimulated release of neuropeptides from rat sensory neurons in culture
    • Vasko MR, Campbell WB, Waite KJ (1994) Prostaglandin E2 enhances bradykinin-stimulated release of neuropeptides from rat sensory neurons in culture. J Neurosci 14:4987-4997
    • (1994) J Neurosci , vol.14 , pp. 4987-4997
    • Vasko, M.R.1    Campbell, W.B.2    Waite, K.J.3
  • 205
    • 0021286757 scopus 로고
    • Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat
    • Wall PD, Woolf CJ (1984) Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat. J Physiol 356:443-458
    • (1984) J Physiol , vol.356 , pp. 443-458
    • Wall, P.D.1    Woolf, C.J.2
  • 206
    • 0023884918 scopus 로고
    • Distribution of cells containing mRNAs encoding substance P and neurokinin B in the rat central nervous system
    • Warden MK, Young WS 3rd (1988) Distribution of cells containing mRNAs encoding substance P and neurokinin B in the rat central nervous system. J Comp Neurol 272:90-113
    • (1988) J Comp Neurol , vol.272 , pp. 90-113
    • Warden, M.K.1    Young Iii, W.S.2
  • 208
    • 0028943638 scopus 로고
    • The cyclic AMP response element in the calcitonin/calcitonin gene-related peptide gene promoter is necessary but not sufficient for its activation by nerve growth factor
    • Watson A, Latchman D (1995) The cyclic AMP response element in the calcitonin/calcitonin gene-related peptide gene promoter is necessary but not sufficient for its activation by nerve growth factor. J Biol Chem 270:9655-9660
    • (1995) J Biol Chem , vol.270 , pp. 9655-9660
    • Watson, A.1    Latchman, D.2
  • 209
    • 0021750080 scopus 로고
    • Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat
    • Wiesenfeld-Hallin Z, Hokflet T, Lundberg JM, Forssmann WG, Reinecke M, Tschopp FA, Fischer JA (1984) Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat. Neurosci Lett 52:199-204
    • (1984) Neurosci Lett , vol.52 , pp. 199-204
    • Wiesenfeld-Hallin, Z.1    Hokflet, T.2    Lundberg, J.M.3    Forssmann, W.G.4    Reinecke, M.5    Tschopp, F.A.6    Fischer, J.A.7
  • 210
    • 0023788882 scopus 로고
    • Sensory transmitters regulate intracellular calcium in dorsal horn neurons
    • Erratum in: Nature (1988) 335:744
    • Womack MD, MacDermott AB, Jessell TM (1988) Sensory transmitters regulate intracellular calcium in dorsal horn neurons. Nature 334:351-353. Erratum in: Nature (1988) 335:744
    • (1988) Nature , vol.334 , pp. 351-353
    • Womack, M.D.1    MacDermott, A.B.2    Jessell, T.M.3
  • 211
    • 0025471841 scopus 로고
    • Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord
    • Woolf CJ, King AE (1990) Dynamic alterations in the cutaneous mechanoreceptive fields of dorsal horn neurons in the rat spinal cord. J Neurosci 10:2717-2726
    • (1990) J Neurosci , vol.10 , pp. 2717-2726
    • Woolf, C.J.1    King, A.E.2
  • 212
    • 0018896233 scopus 로고
    • Responses of spinal neurones to a substance P analogue, noxious pinch and bradykinin
    • Wright DM, Roberts MH (1980) Responses of spinal neurones to a substance P analogue, noxious pinch and bradykinin. Eur J Pharmacol 64:165-167
    • (1980) Eur J Pharmacol , vol.64 , pp. 165-167
    • Wright, D.M.1    Roberts, M.H.2
  • 213
    • 0019314381 scopus 로고
    • Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo
    • Yaksh TL, Jessell TM, Gamse R, Mudge AW, Leeman SE (1980) Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature 286:155-157
    • (1980) Nature , vol.286 , pp. 155-157
    • Yaksh, T.L.1    Jessell, T.M.2    Gamse, R.3    Mudge, A.W.4    Leeman, S.E.5
  • 214
    • 0035882262 scopus 로고    scopus 로고
    • The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1
    • Yaksh TL, Dirig DM, Conway CM, Svensson C, Luo ZD, Isakson PC (2001) The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1. J Neurosci 21:5847-5853
    • (2001) J Neurosci , vol.21 , pp. 5847-5853
    • Yaksh, T.L.1    Dirig, D.M.2    Conway, C.M.3    Svensson, C.4    Luo, Z.D.5    Isakson, P.C.6
  • 215
    • 0032444328 scopus 로고    scopus 로고
    • COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA
    • Yamamoto T, Sakashita Y (1998) COX-2 inhibitor prevents the development of hyperalgesia induced by intrathecal NMDA or AMPA. Neuroreport 9:3869-3873
    • (1998) Neuroreport , vol.9 , pp. 3869-3873
    • Yamamoto, T.1    Sakashita, Y.2
  • 216
    • 0026010260 scopus 로고
    • Stereospecific effects of a nonpeptidic NK1 selective antagonist, CP-96,345: Antinociception in the absence of motor dysfunction
    • Yamamoto T, Yaksh TL (1991) Stereospecific effects of a nonpeptidic NK1 selective antagonist, CP-96,345: antinociception in the absence of motor dysfunction. Life Sci 49:1955-1963
    • (1991) Life Sci , vol.49 , pp. 1955-1963
    • Yamamoto, T.1    Yaksh, T.L.2
  • 217
    • 0025092248 scopus 로고
    • Quantitative autoradiographic distribution of multiple neurokinin binding sites in rat spinal cord
    • Yashpal K, Dam TV, Quirion R (1990) Quantitative autoradiographic distribution of multiple neurokinin binding sites in rat spinal cord. Brain Res 506:259-266
    • (1990) Brain Res , vol.506 , pp. 259-266
    • Yashpal, K.1    Dam, T.V.2    Quirion, R.3
  • 218
    • 0025870245 scopus 로고
    • Effects of dorsal rhizotomy on neurokinin receptor subtypes in the rat spinal cord: A quantitative autoradiographic study
    • Yashpal K, Dam TV, Quirion R (1991) Effects of dorsal rhizotomy on neurokinin receptor subtypes in the rat spinal cord: a quantitative autoradiographic study. Brain Res 552:240-247
    • (1991) Brain Res , vol.552 , pp. 240-247
    • Yashpal, K.1    Dam, T.V.2    Quirion, R.3
  • 219
    • 0027397416 scopus 로고
    • CP-96, 345, but not its stereoisomer, CP-96, 344, blocks the nociceptive responses to intrathecally administered substance P and to noxious thermal and chemical stimuli in the rat
    • Yashpal K, Radhakrishnan V, Coderre TJ, Henry JL (1993) CP-96,345, but not its stereoisomer, CP-96,344, blocks the nociceptive responses to intrathecally administered substance P and to noxious thermal and chemical stimuli in the rat. Neuroscience 52:1039-1047
    • (1993) Neuroscience , vol.52 , pp. 1039-1047
    • Yashpal, K.1    Radhakrishnan, V.2    Coderre, T.J.3    Henry, J.L.4
  • 220
    • 0033622173 scopus 로고    scopus 로고
    • NK3 receptor blockade prevents hyperalgesia and the associated spinal cord substance P release in monoarthritic rats
    • Zaratin P, Angelici O, Clarke GD, Schmid G, Raiteri M, Carita F, Bonanno G (2000) NK3 receptor blockade prevents hyperalgesia and the associated spinal cord substance P release in monoarthritic rats. Neuropharmacology 39:141-149
    • (2000) Neuropharmacology , vol.39 , pp. 141-149
    • Zaratin, P.1    Angelici, O.2    Clarke, G.D.3    Schmid, G.4    Raiteri, M.5    Carita, F.6    Bonanno, G.7
  • 221
    • 0029848988 scopus 로고    scopus 로고
    • Expression of peptides, nitric oxide synthase and NPY receptor in trigeminal and nodose ganglia after nerve lesions
    • Zhang X, Ji RR, Arvidsson J, Lundberg JM, Bartfai T, Bedecs K, Hokfelt T (1996) Expression of peptides, nitric oxide synthase and NPY receptor in trigeminal and nodose ganglia after nerve lesions. Exp Brain Res 111:393-404
    • (1996) Exp Brain Res , vol.111 , pp. 393-404
    • Zhang, X.1    Ji, R.R.2    Arvidsson, J.3    Lundberg, J.M.4    Bartfai, T.5    Bedecs, K.6    Hokfelt, T.7
  • 222
    • 0035122367 scopus 로고    scopus 로고
    • Arthritic calcitonin/ alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity
    • Zhang L, Hoff AO, Wimalawansa SJ, Cote GJ, Gagel RF, Westlund KN (2001) Arthritic calcitonin/ alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity. Pain 89:265-273
    • (2001) Pain , vol.89 , pp. 265-273
    • Zhang, L.1    Hoff, A.O.2    Wimalawansa, S.J.3    Cote, G.J.4    Gagel, R.F.5    Westlund, K.N.6
  • 223
    • 33847790338 scopus 로고    scopus 로고
    • Sensitization of calcitonin generelated peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion
    • Zhang Z, Winborn CS, Marquez de Prado B, Russo AF (2007) Sensitization of calcitonin generelated peptide receptors by receptor activity-modifying protein-1 in the trigeminal ganglion. J Neurosci 27:2693-2703
    • (2007) J Neurosci , vol.27 , pp. 2693-2703
    • Zhang, Z.1    Winborn, C.S.2    Marquez De Prado, B.3    Russo, A.F.4
  • 224
    • 0027530542 scopus 로고
    • Neurokinin B peptide-2 neurons project from the hypothalamus to the thoracolumbar spinal cord of the rat
    • Zhuo H, Helke CJ (1993) Neurokinin B peptide-2 neurons project from the hypothalamus to the thoracolumbar spinal cord of the rat. Neuroscience 52:1019-1028
    • (1993) Neuroscience , vol.52 , pp. 1019-1028
    • Zhuo, H.1    Helke, C.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.