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Heaney DC, MacDonald BK, Everitt A, et al. Socioeconomic variation in incidence of epilepsy: prospective community based study in south east England. BMJ 2002; 325:1013-1016. This is the first study to show in an incident cohort that epilepsy is more likely to affect people in the more deprived segments of the population.
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Gomes MM, Zeitoune RG, Kropf LA, Beeck ES. A house-to-house survey of epileptic seizures in an urban community of Rio de Janeiro, Brazil. Arq Neuropsiquiatr 2002; 60:708-711. This study in Brazil finds prevalence rates within the expected range.
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Epilepsy prevalence in a rural area in Istanbul
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Onal AE, Tumerdem Y, Ozturk MK, et al. Epilepsy prevalence in a rural area in Istanbul. Seizure 2002; 11:397-401. This study in Turkey finds prevalence rates within the expected range.
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Onal, A.E.1
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Aziz H, Ali SM, Frances P, et al. Epilepsy in Pakistan: a population-based epidemiologic study. Epilepsia 1994; 35:950-958.
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Scott RA, Lhatoo SD, Sander JW. The treatment of epilepsy in developing countries: where do we go from here? Bull World Health Organ 2001; 79:344-351.
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Bull World Health Organ
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Meinardi H, Scott RA, Reis R, Sander JW. The treatment gap in epilepsy: the current situation and ways forward. Epilepsia 2001; 42:136-149.
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Epilepsia
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Meinardi, H.1
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The treatment gap and primary health care for people with epilepsy in rural Gambia
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Coleman R, Loppy L, Walraven G. The treatment gap and primary health care for people with epilepsy in rural Gambia. Bull World Health Organ 2002; 80:378-383. This is an interesting account of the practical problems encountered when delivering epilepsy care in a resource-poor country.
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Bull World Health Organ
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Coleman, R.1
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Sander JW. Some aspects of prognosis in the epilepsies: a review. Epilepsia 1993; 34:1007-1016.
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Sander, J.W.1
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Shackleton DP, Westendorp RG, Kasteleijn-Nolst Trenite DG, et al. Survival of patients with epilepsy: an estimate of the mortality risk. Epilepsia 2002; 43:445-450. This is a study showing increased mortality amongst clinic patients in Holland.
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Shackleton, D.P.1
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Epilepsy and mortality: A record linkage study in a U.K. population
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Morgan CL, Kerr MP. Epilepsy and mortality: a record linkage study in a U.K. population. Epilepsia 2002; 43:1251-1255. This is a study showing increased mortality amongst clinic patients in Wales, UK.
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Morgan, C.L.1
Kerr, M.P.2
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Cockerell OC, Johnson AL, Sander JW, et al. Prognosis of epilepsy: a review and further analysis of the first nine years of the British National General Practice Study of Epilepsy, a prospective population-based study. Epilepsia 1997; 38:31-46.
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Cockerell, O.C.1
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MacDonald BK, Johnson AL, Goodridge DM, et al. Factors predicting prognosis of epilepsy after presentation with seizures. Ann Neurol 2000; 48:833-841.
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Ann Neurol
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Kwan P, Brodie MJ. Effectiveness of first antiepileptic drug. Epilepsia 2001; 42:1255-1260. This is a study of the efficacy and tolerability of the first antiepileptic drug in newly diagnosed epilepsy.
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Kwan, P.1
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Does early anti-epileptic drug treatment alter the prognosis for remission of the epilepsies?
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O'Donoghue M, Sander JW. Does early anti-epileptic drug treatment alter the prognosis for remission of the epilepsies? J R Soc Med 1996; 89:245-248.
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Do seizures beget seizures?
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Hauser WA, Lee JR. Do seizures beget seizures? Prog Brain Res 2002; 135:215-219. Very challenging paper, suggesting that in some patients seizures modify brain function increasing the risk for further seizures.
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Prog Brain Res
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Hauser, W.A.1
Lee, J.R.2
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Does antiepileptic drug therapy alter the prognosis of childhood seizures and prevent the development of chronic epilepsy?
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Shinnar S, Berg AT. Does antiepileptic drug therapy alter the prognosis of childhood seizures and prevent the development of chronic epilepsy? Semin Pediatr Neurol 1994; 1:111-117.
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Semin Pediatr Neurol
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Smith D, Defalla BA, Chadwick DW. The misdiagnosis of epilepsy and the management of refractory epilepsy in a specialist clinic. Q J Med 1999; 92:15-23.
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The dynamics of drug treatment in epilepsy: An observational study in an unselected population based cohort with newly diagnosed epilepsy followed up prospectively over 11-14 years
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Lhatoo SD, Sander JW, Shorvon SD. The dynamics of drug treatment in epilepsy: an observational study in an unselected population based cohort with newly diagnosed epilepsy followed up prospectively over 11-14 years. J Neurol Neurosurg Psychiatry 2001; 71:632-637. This long-term study of AED treatment in a large incidence cohort in the UK suggests that the treatment is substandard in at least one in five.
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J Neurol Neurosurg Psychiatry
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Lhatoo, S.D.1
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Rafnsson V, Olafsson E, Hauser WA, et al. Cause-specific mortality in adults with unprovoked seizures: a population-based incidence cohort study. Neuroepidemiology 2001; 20:232-236. This is a study of the causes of death in patients with epilepsy in Iceland.
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Neuroepidemiology
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Rafnsson, V.1
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Death in children with epilepsy: A population-based study
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Camfield CS, Camfield PR, Veugelers PJ. Death in children with epilepsy: a population-based study. Lancet 2002; 359:1891-1895. This is a very important study of mortality in children with epilepsy and it shows that associated neurological disabilities are a major marker for premature death.
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Lancet
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Camfield, C.S.1
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Logroscino G, Hesdorffer DC, Cascino GD, et al. Long-term mortality after a first episode of status epilepticus. Neurology 2002; 58:537-541. This is a study of long-term mortality in patients with status epilepticus in Rochester, Minnesota.
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Neurology
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Logroscino, G.1
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Sillanpaa M, Shinnar S. Status epilepticus in a population-based cohort with childhood-onset epilepsy in Finland. Ann Neurol 2002; 52:303-310. This is a study of the incidence of status epilepticus in a cohort of patients followed for over 30 years in Finland.
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Ann Neurol
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Incidence and mortality of generalized convulsive status epilepticus in California
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Wu YW, Shek DW, Garcia PA, et al. Incidence and mortality of generalized convulsive status epilepticus in California. Neurology 2002; 58:1070-1076. This is a study of the mortality in status epilepticus.
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Neurology
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Wu, Y.W.1
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Risk factors for suicide in epilepsy: A case-control study
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Nilsson L, Ahlbom A, Farahmand BY, et al. Risk factors for suicide in epilepsy: a case-control study. Epilepsia 2002; 43:644-651. This is an important case control study of the risk factors for suicide in people with chronic epilepsy in Sweden. Temporal lobe epilepsy was not found to be a risk factor, contrary to what is often said.
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Epilepsia
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Nilsson, L.1
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Walczak TS, Leppik IE, d'Amelio M, et al. Incidence and risk factors in sudden unexpected death in epilepsy: a prospective cohort study. Neurology 2001; 56:519-525. This case control study in the USA suggests that seizure severity is the major risk factor.
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Neurology
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Walczak, T.S.1
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Donner EJ, Smith CR, Snead OC. Sudden unexplained death in children with epilepsy. Neurology 2001; 57:430-434. This is the largest series of SUDEP in the paediatric age group.
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Donner, E.J.1
Smith, C.R.2
Snead, O.C.3
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Sudden death in epilepsy: A wake-up call for management
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Pedley TA, Hauser WA. Sudden death in epilepsy: a wake-up call for management. Lancet 2002; 359:1790-1791.
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Lancet
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Pedley, T.A.1
Hauser, W.A.2
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An incident case-control study of first unprovoked afebrile seizures in children: A population-based study of pre- and perinatal risk factors
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Sidenvall R, Heijbel J, Blomquist HK, et al. An incident case-control study of first unprovoked afebrile seizures in children: a population-based study of pre- and perinatal risk factors. Epilepsia 2001; 42:1261-1265. Meticulous care was taken in this study with diagnostic accuracy and in carrying out standardized investigations.
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Epilepsia
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Sidenvall, R.1
Heijbel, J.2
Blomquist, H.K.3
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A longitudinal quantitative MRI study of community-based patients with chronic epilepsy and newly diagnosed seizures: Methodology and preliminary findings
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Liu RS, Lemieux L, Bell GS, et al. A longitudinal quantitative MRI study of community-based patients with chronic epilepsy and newly diagnosed seizures: methodology and preliminary findings. Neuroimage 2001; 14:231-243. This is the first population-based study in which sophisticated magnetic resonance imaging techniques were used in the initial assessment of patients with newly diagnosed epilepsy and a control group in the community.
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(2001)
Neuroimage
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, pp. 231-243
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Liu, R.S.1
Lemieux, L.2
Bell, G.S.3
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Disease modification in partial epilepsy
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Walker MC, White HS, Sander JW. Disease modification in partial epilepsy. Brain 2002; 125:1937-1950.
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(2002)
Brain
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Walker, M.C.1
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