The Neuronal Channel NALCN Contributes Resting Sodium Permeability and Is Required for Normal Respiratory Rhythm

Cell

Volumn 129, Issue 2, 2007, Pages 371-383

  Lu, Boxun ^a   Su, Yanhua ^a   Das, Sudipto ^a   Liu, Jin ^a   Xia, Jingsheng ^a   Ren, Dejian ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

HUMDISEASE; MOLNEURO

Indexed keywords

SODIUM CHANNEL; TETRODOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN STEM; BREATHING PATTERN; CONDUCTANCE; CONTROLLED STUDY; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SPINAL CORD;

MUS;

EID: 34147114722     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2007.02.041     Document Type: Article

References (44)

1. Atherton J.F., and Bevan M.D. Ionic mechanisms underlying autonomous action potential generation in the somata and dendrites of GABAergic substantia nigra pars reticulata neurons in vitro. J. Neurosci. 25 (2005) 8272-8281
2. Bargmann C.I. Neurobiology of the Caenorhabditis elegans genome. Science 282 (1998) 2028-2033
3. Bezanilla F. The voltage sensor in voltage-dependent ion channels. Physiol. Rev. 80 (2000) 555-592
4. Catterall W.A. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 26 (2000) 13-25
5. Clapham D.E. TRP channels as cellular sensors. Nature 426 (2003) 517-524
6. Crill W.E. Persistent sodium current in mammalian central neurons. Annu. Rev. Physiol. 58 (1996) 349-362
7. Di Pasquale E., Tell F., Monteau R., and Hilaire G. Perinatal developmental changes in respiratory activity of medullary and spinal neurons: an in vitro study on fetal and newborn rats. Brain Res. Dev. Brain Res. 91 (1996) 121-130
8. Doyle D.A., Morais Cabral J., Pfuetzner R.A., Kuo A., Gulbis J.M., Cohen S.L., Chait B.T., and MacKinnon R. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 280 (1998) 69-77
9. Eggermann E., Bayer L., Serafin M., Saint-Mleux B., Bernheim L., Machard D., Jones B.E., and Muhlethaler M. The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization. J. Neurosci. 23 (2003) 1557-1562
10. Feldman J.L., Mitchell G.S., and Nattie E.E. Breathing: rhythmicity, plasticity, chemosensitivity. Annu. Rev. Neurosci. 26 (2003) 239-266
11. Franks C.J., Pemberton D., Vinogradova I., Cook A., Walker R.J., and Holden-Dye L. Ionic basis of the resting membrane potential and action potential in the pharyngeal muscle of Caenorhabditis elegans. J. Neurophysiol. 87 (2002) 954-961
12. Goldin A.L. Evolution of voltage-gated Na(+) channels. J. Exp. Biol. 205 (2002) 575-584
13. Goldstein S.A., Bayliss D.A., Kim D., Lesage F., Plant L.D., and Rajan S. International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacol. Rev. 57 (2005) 527-540
14. Heinemann S.H., Terlau H., Stuhmer W., Imoto K., and Numa S. Calcium channel characteristics conferred on the sodium channel by single mutations. Nature 356 (1992) 441-443
15. Heurteaux C., Guy N., Laigle C., Blondeau N., Duprat F., Mazzuca M., Lang-Lazdunski L., Widmann C., Zanzouri M., Romey G., and Lazdunski M. TREK-1, a K(+) channel involved in neuroprotection and general anesthesia. EMBO J. 23 (2004) 2684-2695
16. Hille B. Ion Channels of Excitable Membranes. Third Edition (2001), Sinauer Associates, Inc., Sunderland, MA
17. Hodgkin A.L., and Katz B. The effect of sodium ions on the electrical activity of the giant axon of the squid. J. Physiol. 108 (1949) 37-77
18. Horn R. Coupled movements in voltage-gated ion channels. J. Gen. Physiol. 120 (2002) 449-453
19. Jackson A.C., Yao G.L., and Bean B.P. Mechanism of spontaneous firing in dorsomedial suprachiasmatic nucleus neurons. J. Neurosci. 24 (2004) 7985-7998
20. Jones S.W. On the resting potential of isolated frog sympathetic neurons. Neuron 3 (1989) 153-161
21. Kim M.S., Morii T., Sun L.X., Imoto K., and Mori Y. Structural determinants of ion selectivity in brain calcium channel. FEBS Lett. 318 (1993) 145-148
22. Krishnan K.S., and Nash H.A. A genetic study of the anesthetic response: mutants of Drosophila melanogaster altered in sensitivity to halothane. Proc. Natl. Acad. Sci. USA 87 (1990) 8632-8636
23. Lear B.C., Lin J.M., Keath J.R., McGill J.J., Raman I.M., and Allada R. The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker. Neuron 48 (2005) 965-976
24. Lee J.H., Cribbs L.L., and Perez-Reyes E. Cloning of a novel four repeat protein related to voltage-gated sodium and calcium channels. FEBS Lett. 445 (1999) 231-236
25. Littleton J.T., and Ganetzky B. Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron 26 (2000) 35-43
26. Mir B., Iyer S., Ramaswami M., and Krishnan K.S. A genetic and mosaic analysis of a locus involved in the anesthesia response of Drosophila melanogaster. Genetics 147 (1997) 701-712
27. Nash H.A., Scott R.L., Lear B.C., and Allada R. An unusual cation channel mediates photic control of locomotion in Drosophila. Curr. Biol. 12 (2002) 2152-2158
28. Nicholls J.G., Martin A.R., Wallace B.G., and Fuchs P.A. From Neuron to Brain. Fourth Edition (2001), Sinauer Associates Inc., Sunderland, MA
29. Nilius B., Voets T., and Peters J. TRP channels in disease. Sci. STKE 2005 (2005) re8 10.1126/stke.2952005re8
30. Owsianik G., Talavera K., Voets T., and Nilius B. Permeation and selectivity of TRP channels. Annu. Rev. Physiol. 68 (2006) 685-717
31. Pena F., and Ramirez J.M. Substance P-mediated modulation of pacemaker properties in the mammalian respiratory network. J. Neurosci. 24 (2004) 7549-7556
32. Raman I.M., and Bean B.P. Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. J. Neurosci. 17 (1997) 4517-4526
33. Raman I.M., Gustafson A.E., and Padgett D. Ionic currents and spontaneous firing in neurons isolated from the cerebellar nuclei. J. Neurosci. 20 (2000) 9004-9016
34. Ramsey I.S., Delling M., and Clapham D.E. An introduction to TRP channels. Annu. Rev. Physiol. 68 (2006) 619-647
35. Robinson R.B., and Siegelbaum S.A. Hyperpolarization-activated cation currents: from molecules to physiological function. Annu. Rev. Physiol. 65 (2003) 453-480
36. Sather W.A., and McCleskey E.W. Permeation and selectivity in calcium channels. Annu. Rev. Physiol. 65 (2003) 133-159
37. Simasko S.M. A background sodium conductance is necessary for spontaneous depolarizations in rat pituitary cell line GH3. Am. J. Physiol. 266 (1994) C709-C719
38. Strohl K.P. Periodic breathing and genetics. Respir. Physiol. Neurobiol. 135 (2003) 179-185
39. Tang S., Mikala G., Bahinski A., Yatani A., Varadi G., and Schwartz A. Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel. J. Biol. Chem. 268 (1993) 13026-13029
40. van Swinderen B. A succession of anesthetic endpoints in the Drosophila brain. J. Neurobiol. 66 (2006) 1195-1211
41. Viemari J.C., Burnet H., Bevengut M., and Hilaire G. Perinatal maturation of the mouse respiratory rhythm-generator: in vivo and in vitro studies. Eur. J. Neurosci. 17 (2003) 1233-1244
42. Yang X.C., and Sachs F. Block of stretch-activated ion channels in Xenopus oocytes by gadolinium and calcium ions. Science 243 (1989) 1068-1071
43. Yang J., Ellinor P.T., Sather W.A., Zhang J.F., and Tsien R.W. Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels. Nature 366 (1993) 158-161
44. Yu F.H., and Catterall W.A. The VGL-chanome: a protein superfamily specialized for electrical signaling and ionic homeostasis. Sci. STKE 2004 (2004) re15 10.1126/stke.2532004re15