메뉴 건너뛰기




Volumn 131, Issue 5, 2008, Pages 399-405

Ion channels as drug targets: The next GPCRs

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; AMITRIPTYLINE; ANALGESIC AGENT; CALCIUM CHANNEL; ION CHANNEL; LIDOCAINE; N [[2' (AMINOSULFONYL)BIPHENYL 4 YL]METHYL] N METHYL N' [4 (TRIFLUOROMETHOXY)BENZYL]CYCLOPENTANE 1,2 DICARBOXAMIDE; OMEGA CONOTOXIN MVIIA; PROCAINE; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; VOLTAGE GATED SODIUM CHANNEL;

EID: 42949108787     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200709946     Document Type: Review
Times cited : (166)

References (27)
  • 4
    • 33847136022 scopus 로고    scopus 로고
    • Sodium channel blockade may contribute to the analgesic efficacy of antidepressants
    • Dick, I.E., R.M. Brochu, Y. Purohit, G.J. Kaczorowski, W.J. Martin, and B.T. Priest. 2007. Sodium channel blockade may contribute to the analgesic efficacy of antidepressants. J. Pain. 8:315-324.
    • (2007) J. Pain , vol.8 , pp. 315-324
    • Dick, I.E.1    Brochu, R.M.2    Purohit, Y.3    Kaczorowski, G.J.4    Martin, W.J.5    Priest, B.T.6
  • 7
    • 33644877489 scopus 로고    scopus 로고
    • Garcia, M.L., and G.J. Kaczorowski. 2005. Potassium channels as targets for therapeutic intervention. Sci. STKE. 2005:pe46.
    • Garcia, M.L., and G.J. Kaczorowski. 2005. Potassium channels as targets for therapeutic intervention. Sci. STKE. 2005:pe46.
  • 9
    • 34547869800 scopus 로고    scopus 로고
    • High-conductance calcium-activated potassium channels: Validated targets for smooth muscle relaxants?
    • Garcia, M.L., D.-M. Shen, and G.J. Kaczorowski. 2007. High-conductance calcium-activated potassium channels: validated targets for smooth muscle relaxants? Expert Opin. Ther. Patents. 17:832-842.
    • (2007) Expert Opin. Ther. Patents , vol.17 , pp. 832-842
    • Garcia, M.L.1    Shen, D.-M.2    Kaczorowski, G.J.3
  • 10
    • 0036449329 scopus 로고    scopus 로고
    • Cellular fluorescent indicators and voltage/ion probe reader (VIPR) tools for ion channel and receptor drug discovery
    • Gonzalez, J.E., and M.P. Maher. 2002. Cellular fluorescent indicators and voltage/ion probe reader (VIPR) tools for ion channel and receptor drug discovery. Receptors Channels. 8:283-295.
    • (2002) Receptors Channels , vol.8 , pp. 283-295
    • Gonzalez, J.E.1    Maher, M.P.2
  • 13
    • 0003443746 scopus 로고    scopus 로고
    • Third edition. Sinauer Associates, Inc, Sunderland, MA. 814 pp
    • Hille, B. 2001. Ion Channels of Excitable Membranes. Third edition. Sinauer Associates, Inc., Sunderland, MA. 814 pp.
    • (2001) Ion Channels of Excitable Membranes
    • Hille, B.1
  • 16
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • Lifton, R.P., A.G. Gharavi, and D.S. Geller. 2001. Molecular mechanisms of human hypertension. Cell. 104:545-556.
    • (2001) Cell , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 18
    • 1642294294 scopus 로고    scopus 로고
    • Organic chemistry in drug discovery
    • MacCoss, M., and T.A. Baillie. 2004. Organic chemistry in drug discovery. Science. 303:1810-1813.
    • (2004) Science , vol.303 , pp. 1810-1813
    • MacCoss, M.1    Baillie, T.A.2
  • 19
    • 9144272640 scopus 로고    scopus 로고
    • Ziconotide: Neuronal calcium channel blocker for treating severe chronic pain
    • Miljanich, G.P. 2004. Ziconotide: neuronal calcium channel blocker for treating severe chronic pain. Curr. Med. Chem. 11:3029-3040.
    • (2004) Curr. Med. Chem , vol.11 , pp. 3029-3040
    • Miljanich, G.P.1
  • 21
    • 33847148953 scopus 로고    scopus 로고
    • Blocking sodium channels to treat neuropathic pain
    • Priest, B.T., and G.J. Kaczorowski. 2007. Blocking sodium channels to treat neuropathic pain. Expert Opin. Ther. Targets. 11:291-306.
    • (2007) Expert Opin. Ther. Targets , vol.11 , pp. 291-306
    • Priest, B.T.1    Kaczorowski, G.J.2
  • 23
    • 34548250564 scopus 로고    scopus 로고
    • Automated electrophysiology in drug discovery
    • Priest, B.T., A.M. Swensen, and O.B. McManus. 2007. Automated electrophysiology in drug discovery. Curr. Pharm. Des. 13:2325-2337.
    • (2007) Curr. Pharm. Des , vol.13 , pp. 2325-2337
    • Priest, B.T.1    Swensen, A.M.2    McManus, O.B.3
  • 24
    • 34250312096 scopus 로고    scopus 로고
    • Molecular interactions of the gating modifier toxin ProTx-II with Nav 1.5: Implied existence of a novel toxin binding site coupled to activation
    • Smith, J.J., T.R. Cummins, S. Alphy, and K.M. Blumenthal. 2007. Molecular interactions of the gating modifier toxin ProTx-II with Nav 1.5: implied existence of a novel toxin binding site coupled to activation. J. Biol. Chem. 282:12687-12697.
    • (2007) J. Biol. Chem , vol.282 , pp. 12687-12697
    • Smith, J.J.1    Cummins, T.R.2    Alphy, S.3    Blumenthal, K.M.4
  • 26
    • 1642389210 scopus 로고    scopus 로고
    • State-dependent inhibition of L-type calcium channels: Cell-based assay in high-throughput format
    • Xia, M., J.P. Imredy, K.S. Koblan, P. Bennett, and T.M. Connolly. 2004. State-dependent inhibition of L-type calcium channels: cell-based assay in high-throughput format. Anal. Biochem. 327:74-81.
    • (2004) Anal. Biochem , vol.327 , pp. 74-81
    • Xia, M.1    Imredy, J.P.2    Koblan, K.S.3    Bennett, P.4    Connolly, T.M.5
  • 27
    • 15244344363 scopus 로고    scopus 로고
    • The VGL-chanome: A protein superfamily specialized for electrical signaling and ionic homeostasis
    • Yu, F.H., and W.A. Catterall. 2004. The VGL-chanome: a protein superfamily specialized for electrical signaling and ionic homeostasis. Sci. STKE. 2004:re15.
    • (2004) Sci. STKE , vol.2004
    • Yu, F.H.1    Catterall, W.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.