A stomatin and a degenerin interact to control anesthetic sensitivity in Caenorhabditis elegans

Genetics

Volumn 153, Issue 4, 1999, Pages 1673-1682

  Rajaram, Shanta ^a   Spangler, Ted L ^a   Sedensky, Margaret M ^a   Morgan, Phil G ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN;

ANESTHESIA; ARTICLE; CAENORHABDITIS ELEGANS; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ANESTHETICS; ANIMALS; BASE SEQUENCE; BLOOD PROTEINS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; DNA PRIMERS; HELMINTH PROTEINS; MEMBRANE PROTEINS; PROTEIN BINDING;

EID: 0032736428     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. ANTON, A. H., A. I. BERK and C. H. NICHOLLS, 1992 The anesthetic effect of alcohols and alkanes in Caenorhabditis elegans (C.e). Res. Comm. Chem. Pathol. Pharmacol. 78(1): 69-83.
2. BAKER, R., C. MELCHIOR and R. DEITRICH, 1980 The effect of halothane on mice selectively bred for differential sensitivity to alcohol. Pharmacol. Biochem. Behav. 12: 691-695.
3. BRENNER, S., 1974 The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
4. CHALFIE, M., and M. AU, 1989 Genetic control differentiation of the Caenorhabditis elegans touch receptor neurons. Science 243: 1027-1033.
5. CHALFIE, M., and E. WOLINSKY, 1990 The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans. Nature 345: 410-416.
6. CHALFIE, M., Y. TU, G. EUSKIRCHEN, W. W. WARD and D. C. PRASHER, 1994 Green flourescent protein as a marker for gene expression. Science 263: 802-805.
7. CROWDER, C. M., L. D. SHEBESTER and T. SCHEDL, 1996 Behavioral effects of volatile anesthetics in Caenorhabditis elegans. Anesthesioogy 85: 901-912.
8. DRISCOLL, M., and M. CHALFIE, 1991 The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration. Nature 349: 588-593.
9. ECKENHOFF, R. G., 1996a An inhalational anesthetic binding domain in the nicotinic acetylcholine receptor. Proc. Natl. Acad. Sci. USA 93: 2807-2810.
10. ECKENHOFF, R. G., 1996b Amino acid resolution of halothane binding sites in serum albumin. J. Biol. Chem. 271: 15521-15526.
11. FRANKS, N. P., and W. R. LIEB, 1994 Molecular and cellular mechanisms of general anaesthesia. Nature 367: 607-614.
12. 2+-regulatory membrane proteins by halothane. Eur. J. Pharmacol. 365: 91-102.
13. GAMO, S., M. OGAKI and E. NAKASHIMA-TANAKA, 1981 Strain differences in minimum anesthetic concentrations in Drosophila melanogaster. Anesthesiology 54: 289-291.
14. GARCIA-ANOVEROS, J., B. DERFLER, J. NEVILLE-GOLDEN, B. T. HYMAN and D. P. COREY, 1997 BNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc. Natl. Acad. Sci. USA 94: 1459-1463
15. GU, G., G. A. CALDWELL and M. CHALFIE, 1996 Genetic interactions affecting touch sensitivity in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 93: 6577-6582.
16. HECHT, R. M., T. V. NORMAN and W. JONES, 1996 A novel set of uncoordinated mutants in Caenorhabditis elegans uncovered by cold-sensitive mutations. Genome 39: 459-464.
17. HUANG, M., G. GU, E. L. FERGUSON and M. CHALFIE, 1995 A stomatin-like protein necessary for mechanosensation in C. elegans. Nature 378: 292-295.
18. KAYSER, E.-B., P. G. MORGAN and M. M. SEDENSKY, 1999 GAS-1: a mitochondrial protein controls sensitivity to volatile anesthetics in C. elegans. Anesthesiology 90: 545-554.
19. KOBLIN, D. D., 1990 How do inhaled anesthetics work? pp. 67-99 in Anesthesia, Ed. 4, edited by R. D. MILLER. Churchill Livingstone, New York.
20. KOBLIN, D. D., and J. E. DEADY, 1981 Anaesthetic requirement in mice selectively bred for differences in ethanol sensitivity. Br. J. Anaesth. 53: 5-10.
21. KRISHNAN, K. S., and H. A. NASH, 1990 A genetic study of the anesthetic response: mutants of Drosophila melanogaster altered in sensitivity to halothane. Proc. Natl. Acad. Sci. USA 87: 8632-8636.
22. MACIVER, M. B. and J. J. KENDIG, 1991 Anesthetic effects on resting membrane potential are voltage-dependent and agent-specific. Anesthesiology 74: 83-88.
23. MAYER, H., U. SALZER, J. BREUSS, S. ZIEGLER, A. MARCHLER-BAUER et al., 1998 Isolation, molecular characterization, and tissue-specific expression of a novel putative G protein-coupled receptor. Biochim. Biophys. Acta 1395: 301-308.
24. MCCRAE, A. F., E. J. GALLAHER, P. M. WINTER and L. L. FIRESTONE, 1993 Volatile anesthetic requirements differ in mice selectively bred for sensitivity or resistance to diazepam: implications for the site of anesthesia. Anesth. Analg. 76: 1313-1317.
25. MEYER, H. H., 1890 Theorie der Alkoholnarkose. Arche Exp. Pathol. Pharmakol. 42: 109.
26. MILLER, K. W., L. L. FIRESTONE, J. K. ALIFIMOFF and P. STREICHER, 1989 Nonanesthetic alcohols dissolve in synaptic membranes without pertubing their lipids. Proc. Natl. Acad. Sci. USA 86: 1084-1087.
27. MORGAN, P. G., and H. F. CASCORBI, 1985 Effect of anesthetics and a convulsant on normal and mutant Caenorhabditis elegans. Anesthesiology 62: 738-744.
28. MORGAN, P. G., and M. M. SEDENSKY, 1994 Mutations conferring new patterns of sensitivity to volatile anesthetics in C. elegans. Anesthesiology 81: 888-898.
29. MORGAN, P. G., M. M. SEDENSKY and P. M. MENEELY, 1990 Multiple sites of action of volatile anesthetics in C. elegans. Proc. Natl. Acad. Sci. USA 87: 2965-2969.
30. OVERTON, E., 1901 Studien Üher die Narkose. Verlag von Guston Fischer, Jena.
31. PARK, E. C., and H. R. HORVITZ, 1986 Mutations with dominant effects on the behavior and morphology of the nematode Caenorhabditis eleagans. Genetics 113: 821-852.
32. RAJARAM, S., M. M. SEDENSKY and P. G. MORGAN, 1998 A stomatin homologue controls sensitivity to volatile anesthetics in C. elegans. Proc. Natl. Acad. Sci. USA 95: 8761-8766.
33. SEDENSKY, M. M., and P. M. MENEELY, 1987 Genetic analysis of halothane sensitivity in C. elegans. Science 236: 952-954.
34. SEDENSKY, M. M., H. F. CASCORBI, J. MEINWALD, P. RADFORD and P. G. MORGAN, 1994 Genetic differences affecting the potency of stereoisomers of halothane. Proc. Natl. Acad. Sci. USA 91: 10054-10058.
35. SEIDEL, G., and R. PROHASKA, 1998 Molecular cloning of hSLP-1, a novel human brain-specific member of the band 7/MEC-2 family similar to Caenorhabditis elegans UNC-24. Gene 225: 23-29.
36. SHREFFLER, W., T. MAGARDINO, K. SHEKDAR and E. WOLINSKY, 1995 The unc-8 and sup-40 genes regulate ion channel function in Caenorhabditis elegans motorneurons. Genetics 139: 1261-1272.
37. SNYERS, L., E. UMLAUF and R. PROHASKA, 1998 Oligomeric nature of the integral membrane protein stomatin. J. Biol. Chem. 273: 17221-17226.
38. STEWART, G. W., A. C. ARGENT and B. C. J. DASH, 1993 Stomalin: a putative cation transport regulator in red cell membrane. Biochim. Biophys. Acta 1225: 15-25.
39. TAVERNARAKIS, N., W. SHREFFLER, S. WANG and M. DRISCOLL, 1997 unc-8, a DEG/ENaC family member, encodes a subunit of a candidate mechanically gated channel that modulates C. elegans locomotion. Neuron 18: 107-119.
40. VAN SWINDEREN, B., O. SAIFEE, L. SHEBESTER, R. ROBERSON, M. L. NONET et al., 1999 A neomorphic syntaxin mutation blocks volatile-anesthetic action in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 96: 2479-2481.
41. WAUD, D. R., 1970 On biological assays involving quantal responses. J. Pharmacol. Exp. Ther. 183: 577-607.