Estrogen-provided cardiac protection following burn trauma is mediated through a reduction in mitochondria-derived DAMPs

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 6, 2014, Pages

  Yao, Xiao ^a   Wigginton, Jane G ^a   Maass, David L ^a   Ma, Lisha ^a   Carlson, Deborah ^a   Wolf, Steven E ^a   Minei, Joseph P ^a   Zang, Qun S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Burn; DAMPs; Estrogen; Heart failure; Mitochondrial damage; Myocardial inflammation

Indexed keywords

CASPASE 3; CYTOCHROME C; ESTRADIOL; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LIPID; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TROPONIN I; TUMOR NECROSIS FACTOR ALPHA; CARDIOTONIC AGENT; CASPASE; CYTOKINE; ESTROGEN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BODY SURFACE; BURN; CARDITIS; CELL STRUCTURE; CELLULAR PARAMETERS; CONTROLLED STUDY; CYTOPLASM; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVITY; HEART; HEART FUNCTION; HEART MITOCHONDRION; HEART MUSCLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE INJURY; HEART PROTECTION; LIPID PEROXIDATION; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION DERIVED DANGER ASSOCIATED MOLECULAR PATTERN; MORPHOLOGY; MYOCARDITIS; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RESPIRATORY FUNCTION; SCALD; ANIMAL; DAMPS; DRUG EFFECT; HEART DISEASE; HEART FAILURE; METABOLISM; MITOCHONDRIAL DAMAGE; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

BURN; DAMPS; ESTROGEN; HEART FAILURE; MITOCHONDRIAL DAMAGE; MYOCARDIAL INFLAMMATION;

ANIMALS; APOPTOSIS; BURNS; CARDIOTONIC AGENTS; CASPASES; CYTOCHROMES C; CYTOKINES; DNA, MITOCHONDRIAL; ESTRADIOL; GLUTATHIONE PEROXIDASE; HEART DISEASES; HYDROGEN PEROXIDE; MALE; MITOCHONDRIA, HEART; MODELS, ANIMAL; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84900536185     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00475.2013     Document Type: Article

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