-
1
-
-
0031897632
-
NF-κB and rel proteins - evolutionarily conserved mediators of immune responses
-
Ghosh S.et al. NF-κB and rel proteins - evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:1998;225-260.
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
-
2
-
-
0029874138
-
The NF-κB and IκB proteins: New discoveries and insights
-
Baldwin A.S. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14:1996;649-683.
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 649-683
-
-
Baldwin, A.S.1
-
3
-
-
0031126395
-
IκB proteins - structure, function and regulation
-
Whiteside S.T., Israel A. IκB proteins - structure, function and regulation. Sem. Cancer Biol. 8:1997;75-82.
-
(1997)
Sem. Cancer Biol.
, vol.8
, pp. 75-82
-
-
Whiteside, S.T.1
Israel, A.2
-
4
-
-
0027332498
-
The IκB proteins - multifunctional regulators of Rel/NF-κB transcription factors
-
Beg A.A., Baldwin A.S. The IκB proteins - multifunctional regulators of Rel/NF-κB transcription factors. Genes Dev. 7:1993;2064-2070.
-
(1993)
Genes Dev.
, vol.7
, pp. 2064-2070
-
-
Beg, A.A.1
Baldwin, A.S.2
-
5
-
-
0028971289
-
Rel/NF-κB/IκB family: Intimate tales of association and dissociation
-
Verma I.M.et al. Rel/NF-κB/IκB family: intimate tales of association and dissociation. Genes Dev. 9:1995;2723-2735.
-
(1995)
Genes Dev.
, vol.9
, pp. 2723-2735
-
-
Verma, I.M.1
-
6
-
-
0031586174
-
Identification and characterization of an IκB kinase
-
Regnier C.H.et al. Identification and characterization of an IκB kinase. Cell. 90:1997;373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
-
7
-
-
0032541657
-
IKK-γ is an essential regulatory subunit of the IκB kinase complex
-
Rothwarf D.M.et al. IKK-γ is an essential regulatory subunit of the IκB kinase complex. Nature. 395:1998;297-300.
-
(1998)
Nature
, vol.395
, pp. 297-300
-
-
Rothwarf, D.M.1
-
8
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation
-
Yamaoka S.et al. Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation. Cell. 93:1998;1231-1240.
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
-
9
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
Didonato J.A.et al. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature. 388:1997;548-554.
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
Didonato, J.A.1
-
10
-
-
0030685825
-
IKK-1 and IKK-2 - cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio F.et al. IKK-1 and IKK-2 - cytokine-activated IκB kinases essential for NF-κB activation. Science. 278:1997;860-866.
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
-
11
-
-
0030611595
-
IκB-kinase-β-NF-κB activation and complex formation with IκB kinase-α and NIK
-
Woronicz J.D.et al. IκB-kinase-β-NF-κB activation and complex formation with IκB kinase-α and NIK. Science. 278:1997;866-869.
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
-
12
-
-
0030613551
-
The IκB kinase complex (IKK) contains two kinase subunits, IKK-α and IKK-β, necessary for IκB phosphorylation and NF-κB activation
-
Zandi E.et al. The IκB kinase complex (IKK) contains two kinase subunits, IKK-α and IKK-β, necessary for IκB phosphorylation and NF-κB activation. Cell. 91:1997;243-252.
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
-
13
-
-
0032589935
-
IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex
-
Mercurio F.et al. IκB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex. Mol. Cell. Biol. 19:1999;1526-1538.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1526-1538
-
-
Mercurio, F.1
-
15
-
-
0033002197
-
Bridging the gap: Composition, regulation and physiological function of the IκB kinase complex
-
Zandi E., Karin M. Bridging the gap: composition, regulation and physiological function of the IκB kinase complex. Mol. Cell. Biol. 19:1999;4547-4551.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4547-4551
-
-
Zandi, E.1
Karin, M.2
-
16
-
-
0033106149
-
A ubiquitin ligase complex essential for the NF-κ B, Wnt/Wingless, and Hedgehog signaling pathways
-
Maniatis T. A ubiquitin ligase complex essential for the NF-κ B, Wnt/Wingless, and Hedgehog signaling pathways. Genes Dev. 13:1999;505-510.
-
(1999)
Genes Dev.
, vol.13
, pp. 505-510
-
-
Maniatis, T.1
-
17
-
-
0033537719
-
Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation
-
Delhase M.et al. Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation. Science. 284:1999;309-313.
-
(1999)
Science
, vol.284
, pp. 309-313
-
-
Delhase, M.1
-
18
-
-
0033532386
-
The IKKβ subunit of IκB kinase (IKK) is essential for Nuclear Factor kappa B activation and prevention of apoptosis
-
Li Z.W.et al. The IKKβ subunit of IκB kinase (IKK) is essential for Nuclear Factor kappa B activation and prevention of apoptosis. J. Exp. Med. 189:1999;1839-1845.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1839-1845
-
-
Li, Z.W.1
-
19
-
-
0033537739
-
Severe liver degeneration in mice lacking the IκB kinase 2 gene
-
Li Q.T.et al. Severe liver degeneration in mice lacking the IκB kinase 2 gene. Science. 284:1999;321-325.
-
(1999)
Science
, vol.284
, pp. 321-325
-
-
Li, Q.T.1
-
20
-
-
0033119952
-
Embryonic lethality, liver degeneration and impaired NF-κB activation in IKKβ-deficient mice
-
Tanaka M.et al. Embryonic lethality, liver degeneration and impaired NF-κB activation in IKKβ-deficient mice. Immunity. 10:1999;421-429.
-
(1999)
Immunity
, vol.10
, pp. 421-429
-
-
Tanaka, M.1
-
21
-
-
0033563227
-
IKK1-deficient mice exhibit abnormal development of skin and skeleton
-
Li Q.T.et al. IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev. 13:1999;1322-1328.
-
(1999)
Genes Dev.
, vol.13
, pp. 1322-1328
-
-
Li, Q.T.1
-
22
-
-
0033537767
-
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
-
Hu Y.L.et al. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase. Science. 284:1999;316-320.
-
(1999)
Science
, vol.284
, pp. 316-320
-
-
Hu, Y.L.1
-
23
-
-
0033537757
-
Limb and skin abnormalities in mice lacking IKKα
-
Takeda K.et al. Limb and skin abnormalities in mice lacking IKKα Science. 284:1999;313-316.
-
(1999)
Science
, vol.284
, pp. 313-316
-
-
Takeda, K.1
-
24
-
-
0032477945
-
Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB
-
Seitz C.S.et al. Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB. Proc. Natl. Acad. Sci. U. S. A. 95:1998;2307-2312.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 2307-2312
-
-
Seitz, C.S.1
-
25
-
-
0033565763
-
Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappa B signaling
-
van Hogerlinden M.et al. Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-kappa B signaling. Cancer Res. 59:1999;3299-3303.
-
(1999)
Cancer Res.
, vol.59
, pp. 3299-3303
-
-
Van Hogerlinden, M.1
-
26
-
-
0032499286
-
Role of rel/NF-κB transcription factors during the outgrowth of the vertebrate limb
-
Kanegae Y.et al. Role of rel/NF-κB transcription factors during the outgrowth of the vertebrate limb. Nature. 392:1998;611-614.
-
(1998)
Nature
, vol.392
, pp. 611-614
-
-
Kanegae, Y.1
-
27
-
-
0032498962
-
Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis
-
Bushdid P.B.et al. Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis. Nature. 392:1998;615-618.
-
(1998)
Nature
, vol.392
, pp. 615-618
-
-
Bushdid, P.B.1
-
28
-
-
0032589261
-
IKKγ mediates the interaction of cellular IκB kinases with the Tax transforming protein of human-T-cell-leukemia-virus type 1
-
Chu Z.L.et al. IKKγ mediates the interaction of cellular IκB kinases with the Tax transforming protein of human-T-cell-leukemia-virus type 1. J. Biol. Chem. 274:1999;15297-15300.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15297-15300
-
-
Chu, Z.L.1
-
29
-
-
0034175632
-
Severe liver degeneration and lack of NF-κB activation in NEMO/IKK-γ deficient mice
-
(in press)
-
Rudolph D.et al. Severe liver degeneration and lack of NF-κB activation in NEMO/IKK-γ deficient mice. Genes Dev. 2000;. (in press).
-
(2000)
Genes Dev.
-
-
Rudolph, D.1
-
30
-
-
0033514445
-
Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis
-
Li Y.et al. Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis. Proc. Natl. Acad. Sci. U. S. A. 96:1999;1042-1047.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 1042-1047
-
-
Li, Y.1
-
31
-
-
0032541670
-
IKAP is a scaffold protein of the IκB kinase complex
-
Cohen L.et al. IKAP is a scaffold protein of the IκB kinase complex. Nature. 395:1998;292-296.
-
(1998)
Nature
, vol.395
, pp. 292-296
-
-
Cohen, L.1
-
32
-
-
0033545909
-
The kinetics of association and phosphorylation of IκB isoforms by IκB kinase 2 correlate with their cellular regulation in human endothelial cells
-
Heilker R.et al. The kinetics of association and phosphorylation of IκB isoforms by IκB kinase 2 correlate with their cellular regulation in human endothelial cells. Biochemistry. 38:1999;6231-6238.
-
(1999)
Biochemistry
, vol.38
, pp. 6231-6238
-
-
Heilker, R.1
-
33
-
-
0032808084
-
IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases
-
Shimada T.et al. IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IκB kinases. Int. Immunol. 11:1999;1357-1362.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1357-1362
-
-
Shimada, T.1
-
34
-
-
0033623848
-
IKKε is part of a novel PMA-inducible IκB kinase complex
-
(in press)
-
Peters R.T.et al. IKKε is part of a novel PMA-inducible IκB kinase complex. Mol. Cell. 2000;. (in press).
-
(2000)
Mol. Cell
-
-
Peters, R.T.1
-
35
-
-
0032530455
-
Tumor-necrosis-factor-receptor-associated factors (TRAFs) - a family of adaptor proteins that regulates life and death
-
Arch R.H.et al. Tumor-necrosis-factor-receptor-associated factors (TRAFs) - a family of adaptor proteins that regulates life and death. Genes Dev. 12:1998;2821-2830.
-
(1998)
Genes Dev.
, vol.12
, pp. 2821-2830
-
-
Arch, R.H.1
-
36
-
-
0033580466
-
The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji J.et al. The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature. 398:1999;252-256.
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
-
37
-
-
0033537866
-
Functional interactions of transforming growth factor beta-activated kinase 1 with IκB kinases to stimulate NF-κB activation
-
Sakurai H.et al. Functional interactions of transforming growth factor beta-activated kinase 1 with IκB kinases to stimulate NF-κB activation. J. Biol. Chem. 274:1999;10641-10648.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10641-10648
-
-
Sakurai, H.1
-
38
-
-
0033082990
-
The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-κB acting through the NF-κB-inducing kinase and IκB kinases
-
Lin X.et al. The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-κB acting through the NF-κB-inducing kinase and IκB kinases. Immunity. 10:1999;271-280.
-
(1999)
Immunity
, vol.10
, pp. 271-280
-
-
Lin, X.1
-
39
-
-
0032930861
-
Alymphoplasia is caused by a point mutation in the mouse gene encoding NF-κB-inducing kinase
-
Shinkura R.et al. Alymphoplasia is caused by a point mutation in the mouse gene encoding NF-κB-inducing kinase. Nat. Genet. 22:1999;74-77.
-
(1999)
Nat. Genet.
, vol.22
, pp. 74-77
-
-
Shinkura, R.1
-
40
-
-
0033517189
-
NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes O.N.et al. NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature. 401:1999;82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
-
41
-
-
0033517190
-
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
-
Romashkova J.A., Makarov S.S. NF-κB is a target of AKT in anti-apoptotic PDGF signalling. Nature. 401:1999;86-90.
-
(1999)
Nature
, vol.401
, pp. 86-90
-
-
Romashkova, J.A.1
Makarov, S.S.2
-
42
-
-
0033038491
-
Activation of phosphatidylinositol-3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-κB p65/RelA subunit
-
Sizemore N.et al. Activation of phosphatidylinositol-3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-κB p65/RelA subunit. Mol. Cell. Biol. 19:1999;4798-4805.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4798-4805
-
-
Sizemore, N.1
-
43
-
-
0033551607
-
IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein
-
Harhaj E.W., Sun S.C. IKKγ serves as a docking subunit of the IκB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein. J. Biol. Chem. 274:1999;22911-22914.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22911-22914
-
-
Harhaj, E.W.1
Sun, S.C.2
-
44
-
-
0033580931
-
Role of adapter function in oncoprotein-mediated activation of NF-κB - human T-cell leukemia virus type I Tax interacts directly with IKKγ
-
Jin D.Y.et al. Role of adapter function in oncoprotein-mediated activation of NF-κB - human T-cell leukemia virus type I Tax interacts directly with IKKγ J. Biol. Chem. 274:1999;17402-17405.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17402-17405
-
-
Jin, D.Y.1
-
45
-
-
0033485542
-
NF-κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-releated kinase
-
Pomerantz J.L.et al. NF-κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-releated kinase. EMBO J. 18:1999;6694-6704.
-
(1999)
EMBO J.
, vol.18
, pp. 6694-6704
-
-
Pomerantz, J.L.1
-
46
-
-
0034643170
-
NAK is an I kappa B kinase-activating kinase
-
(in press)
-
Tojima Y.et al. NAK is an I kappa B kinase-activating kinase. Nature. 2000;. (in press).
-
(2000)
Nature
-
-
Tojima, Y.1
|