Loss of estrogen receptor β decreases mitochondrial energetic potential and increases thrombogenicity of platelets in aged female mice

Age

Volumn 32, Issue 1, 2010, Pages 109-121

  Jayachandran, Muthuvel ^a,b   Preston, Claudia C ^a   Hunter, Larry W ^a   Jahangir, Arshad ^a   Owen, Whyte G ^b   Korach, Kenneth S ^c   Miller, Virginia M ^a,b  

^a Mayo Clinic   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Aging; Estrogen receptors; Microparticles; Mitochondria; Platelet energy metabolism; Procoagulant activity

Indexed keywords

CYTOCHROME C OXIDASE; ESTROGEN RECEPTOR BETA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; UBIQUINOL CYTOCHROME C REDUCTASE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; ENERGY METABOLISM; ENERGY TRANSFER; FEMALE; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; SPLEEN; SPLEEN WEIGHT; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOGENICITY;

ANIMALS; BLOOD PLATELETS; BODY WEIGHT; ELECTRON TRANSPORT COMPLEX III; ELECTRON TRANSPORT COMPLEX IV; ENERGY METABOLISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESTRADIOL; ESTROGEN RECEPTOR BETA; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; FOLLICLE STIMULATING HORMONE; LACTATES; MICE; MICE, INBRED STRAINS; MITOCHONDRIA; NADH DEHYDROGENASE; ORGAN SIZE; OXYGEN; PLATELET AGGREGATION;

EID: 77949424933     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-009-9119-y     Document Type: Article

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