SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis

Genes to Cells

Volumn 16, Issue 1, 2011, Pages 34-45

  Li, Yanze ^a,b   Matsumori, Haruka ^a   Nakayama, Yuji ^a   Osaki, Mitsuhiko ^b   Kojima, Hirotada ^c   Kurimasa, Akihiro ^a   Ito, Hisao ^a   Mori, Seiichi ^d   Katoh, Motonobu ^a   Oshimura, Mitsuo ^b   Inoue, Toshiaki ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

E1A ASSOCIATED P300 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN INHIBITOR; SIRTUIN 2;

APOPTOSIS; ARTICLE; CANCER THERAPY; CELL CYCLE ARREST; CELL LINE; CELL STRESS; CELL SURVIVAL; DEACETYLATION; DOWN REGULATION; DRUG TARGETING; GENOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; E1A-ASSOCIATED P300 PROTEIN; HELA CELLS; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA, SMALL INTERFERING; SIRTUIN 2; SIRTUINS; TUMOR SUPPRESSOR PROTEIN P53;

MAMMALIA;

EID: 78650638268     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2010.01460.x     Document Type: Article

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