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Volumn 41, Issue 3, 2014, Pages 185-194

T helper subsets & regulatory T cells: Rethinking the paradigm in the clinical context of solid organ transplantation

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN;

EID: 84900404358     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/iji.12106     Document Type: Article
Times cited : (29)

References (101)
  • 1
    • 70350774322 scopus 로고    scopus 로고
    • Differential effect of cyclosporine and mycophenolic acid on the human regulatory T cells and TH-17 cells balance
    • Abadja, F., Videcoq, C., Alamartine, E., Berthoux, F. & Mariat, C. (2009) Differential effect of cyclosporine and mycophenolic acid on the human regulatory T cells and TH-17 cells balance. Transplantation Proceedings, 41, 3367.
    • (2009) Transplantation Proceedings , vol.41 , pp. 3367
    • Abadja, F.1    Videcoq, C.2    Alamartine, E.3    Berthoux, F.4    Mariat, C.5
  • 2
    • 80051724276 scopus 로고    scopus 로고
    • Impact of mycophenolic acid and tacrolimus on Th17-related immune response
    • Abadja, F., Atemkeng, S., Alamartine, E., Berthoux, F. & Mariat, C. (2011a) Impact of mycophenolic acid and tacrolimus on Th17-related immune response. Transplantation, 92, 396.
    • (2011) Transplantation , vol.92 , pp. 396
    • Abadja, F.1    Atemkeng, S.2    Alamartine, E.3    Berthoux, F.4    Mariat, C.5
  • 4
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A.K., Murphy, K.M. & Sher, A. (1996) Functional diversity of helper T lymphocytes. Nature, 383, 787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 6
    • 40049084327 scopus 로고    scopus 로고
    • Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases
    • e651.
    • Akkoc, T., de Koning, P.J., Ruckert, B., Barlan, I., Akdis, M. & Akdis, C.A. (2008) Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases. The Journal of Allergy and Clinical Immunology, 121, 652 e651.
    • (2008) The Journal of Allergy and Clinical Immunology , vol.121 , pp. 652
    • Akkoc, T.1    de Koning, P.J.2    Ruckert, B.3    Barlan, I.4    Akdis, M.5    Akdis, C.A.6
  • 10
    • 65549152333 scopus 로고    scopus 로고
    • Th17 cells: from precursors to players in inflammation and infection
    • Awasthi, A. & Kuchroo, V.K. (2009) Th17 cells: from precursors to players in inflammation and infection. International Immunology, 21, 489.
    • (2009) International Immunology , vol.21 , pp. 489
    • Awasthi, A.1    Kuchroo, V.K.2
  • 11
    • 77956336990 scopus 로고    scopus 로고
    • iTregs by vitamins: commentary on 'retinoic acid attenuates acute heart rejection by increasing regulatory T cell and repressing differentiation of Th17 in the presence of TGF-ss'
    • Baan, C.C. (2010) iTregs by vitamins: commentary on 'retinoic acid attenuates acute heart rejection by increasing regulatory T cell and repressing differentiation of Th17 in the presence of TGF-ss'. Transplant International, 23, 984.
    • (2010) Transplant International , vol.23 , pp. 984
    • Baan, C.C.1
  • 13
    • 33845379986 scopus 로고    scopus 로고
    • Rapamycin promotes expansion of functional CD4 + CD25 + FOXP3 +  regulatory T cells of both healthy subjects and type 1 diabetic patients
    • Battaglia, M., Stabilini, A., Migliavacca, B., Horejs-Hoeck, J., Kaupper, T. & Roncarolo, M.G. (2006) Rapamycin promotes expansion of functional CD4 + CD25 + FOXP3 +  regulatory T cells of both healthy subjects and type 1 diabetic patients. Journal of Immunology, 177, 8338.
    • (2006) Journal of Immunology , vol.177 , pp. 8338
    • Battaglia, M.1    Stabilini, A.2    Migliavacca, B.3    Horejs-Hoeck, J.4    Kaupper, T.5    Roncarolo, M.G.6
  • 15
    • 67649595496 scopus 로고    scopus 로고
    • Deficient TNF-alpha and IFN-gamma production correlates with nondetectable donor-specific cytotoxicity after clinical kidney transplantation
    • van Besouw, N.M., de Kuiper, R., van der Mast, B.J., van de Wetering, J., Baan, C.C. & Weimar, W. (2009) Deficient TNF-alpha and IFN-gamma production correlates with nondetectable donor-specific cytotoxicity after clinical kidney transplantation. Transplantation, 87, 1451.
    • (2009) Transplantation , vol.87 , pp. 1451
    • Van Besouw, N.M.1    de Kuiper, R.2    van der Mast, B.J.3    van de Wetering, J.4    Baan, C.C.5    Weimar, W.6
  • 16
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Carrier, Y., Gao, W., Korn, T., Strom, T.B., Oukka, M., Weiner, H.L. & Kuchroo, V.K. (2006) Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature, 441, 235.
    • (2006) Nature , vol.441 , pp. 235
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 17
    • 0034606359 scopus 로고    scopus 로고
    • Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
    • Breitfeld, D., Ohl, L., Kremmer, E., Ellwart, J., Sallusto, F., Lipp, M. & Forster, R. (2000) Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. Journal of Experimental Medicine, 192, 1545.
    • (2000) Journal of Experimental Medicine , vol.192 , pp. 1545
    • Breitfeld, D.1    Ohl, L.2    Kremmer, E.3    Ellwart, J.4    Sallusto, F.5    Lipp, M.6    Forster, R.7
  • 19
    • 56149107712 scopus 로고    scopus 로고
    • CD8 +  Th17 mediate costimulation blockade-resistant allograft rejection in T-bet-deficient mice
    • Burrell, B.E., Csencsits, K., Lu, G., Grabauskiene, S. & Bishop, D.K. (2008) CD8 +  Th17 mediate costimulation blockade-resistant allograft rejection in T-bet-deficient mice. Journal of Immunology, 181, 3906.
    • (2008) Journal of Immunology , vol.181 , pp. 3906
    • Burrell, B.E.1    Csencsits, K.2    Lu, G.3    Grabauskiene, S.4    Bishop, D.K.5
  • 20
    • 79959328032 scopus 로고    scopus 로고
    • ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
    • Choi, Y.S., Kageyama, R., Eto, D., Escobar, T.C., Johnston, R.J., Monticelli, L., Lao, C. & Crotty, S. (2011) ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity, 34, 932.
    • (2011) Immunity , vol.34 , pp. 932
    • Choi, Y.S.1    Kageyama, R.2    Eto, D.3    Escobar, T.C.4    Johnston, R.J.5    Monticelli, L.6    Lao, C.7    Crotty, S.8
  • 21
    • 2942755979 scopus 로고    scopus 로고
    • T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
    • Chtanova, T., Tangye, S.G., Newton, R., Frank, N., Hodge, M.R., Rolph, M.S. & Mackay, C.R. (2004) T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. Journal of Immunology, 173, 68.
    • (2004) Journal of Immunology , vol.173 , pp. 68
    • Chtanova, T.1    Tangye, S.G.2    Newton, R.3    Frank, N.4    Hodge, M.R.5    Rolph, M.S.6    Mackay, C.R.7
  • 22
    • 84864327434 scopus 로고    scopus 로고
    • Dysregulation of Th17 cells during the early post-transplant period in patients under calcineurin inhibitor based immunosuppression
    • Chung, B.H., Kim, K.W., Kim, B.M., Piao, S.G., Lim, S.W., Choi, B.S., Park, C.W., Kim, Y.S., Cho, M.L. & Yang, C.W. (2012) Dysregulation of Th17 cells during the early post-transplant period in patients under calcineurin inhibitor based immunosuppression. PLoS ONE, 7, e42011.
    • (2012) PLoS ONE , vol.7
    • Chung, B.H.1    Kim, K.W.2    Kim, B.M.3    Piao, S.G.4    Lim, S.W.5    Choi, B.S.6    Park, C.W.7    Kim, Y.S.8    Cho, M.L.9    Yang, C.W.10
  • 25
    • 0025784062 scopus 로고
    • Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction
    • Dallman, M.J., Larsen, C.P. & Morris, P.J. (1991) Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction. Journal of Experimental Medicine, 174, 493.
    • (1991) Journal of Experimental Medicine , vol.174 , pp. 493
    • Dallman, M.J.1    Larsen, C.P.2    Morris, P.J.3
  • 26
  • 29
  • 30
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino, D.F., Bond, M.W. & Mosmann, T.R. (1989) Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. Journal of Experimental Medicine, 170, 2081.
    • (1989) Journal of Experimental Medicine , vol.170 , pp. 2081
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 32
    • 34250156673 scopus 로고    scopus 로고
    • Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells
    • Gao, W., Lu, Y., El Essawy, B., Oukka, M., Kuchroo, V.K. & Strom, T.B. (2007) Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells. American Journal of Transplantation, 7, 1722.
    • (2007) American Journal of Transplantation , vol.7 , pp. 1722
    • Gao, W.1    Lu, Y.2    El Essawy, B.3    Oukka, M.4    Kuchroo, V.K.5    Strom, T.B.6
  • 33
    • 38149051604 scopus 로고    scopus 로고
    • Interleukin-12 family members and the balance between rejection and tolerance
    • Goriely, S. & Goldman, M. (2008) Interleukin-12 family members and the balance between rejection and tolerance. Current Opinion in Organ Transplantation, 13, 4.
    • (2008) Current Opinion in Organ Transplantation , vol.13 , pp. 4
    • Goriely, S.1    Goldman, M.2
  • 36
    • 38049144850 scopus 로고    scopus 로고
    • Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation
    • Haynes, N.M., Allen, C.D., Lesley, R., Ansel, K.M., Killeen, N. & Cyster, J.G. (2007) Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation. Journal of Immunology, 179, 5099.
    • (2007) Journal of Immunology , vol.179 , pp. 5099
    • Haynes, N.M.1    Allen, C.D.2    Lesley, R.3    Ansel, K.M.4    Killeen, N.5    Cyster, J.G.6
  • 37
    • 79954787760 scopus 로고    scopus 로고
    • Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy
    • Hester, J., Mills, N., Shankar, S., Carvalho-Gaspar, M., Friend, P. & Wood, K.J. (2011) Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy. Transplantation, 91, 744.
    • (2011) Transplantation , vol.91 , pp. 744
    • Hester, J.1    Mills, N.2    Shankar, S.3    Carvalho-Gaspar, M.4    Friend, P.5    Wood, K.J.6
  • 39
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., Nomura, T. & Sakaguchi, S. (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science, 299, 1057.
    • (2003) Science , vol.299 , pp. 1057
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 42
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17 +  T helper cells
    • Ivanov, I.I., McKenzie, B.S., Zhou, L., Tadokoro, C.E., Lepelley, A., Lafaille, J.J., Cua, D.J. & Littman, D.R. (2006) The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17 +  T helper cells. Cell, 126, 1121.
    • (2006) Cell , vol.126 , pp. 1121
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 43
    • 78751648601 scopus 로고    scopus 로고
    • Clinical significance of regulatory T-cell-related gene expression in peripheral blood after renal transplantation
    • Iwase, H., Kobayashi, T., Kodera, Y., Miwa, Y., Kuzuya, T., Iwasaki, K. et al. (2010) Clinical significance of regulatory T-cell-related gene expression in peripheral blood after renal transplantation. Transplantation, 91, 191.
    • (2010) Transplantation , vol.91 , pp. 191
    • Iwase, H.1    Kobayashi, T.2    Kodera, Y.3    Miwa, Y.4    Kuzuya, T.5    Iwasaki, K.6
  • 44
    • 0028943484 scopus 로고
    • Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
    • Jacobson, N.G., Szabo, S.J., Weber-Nordt, R.M., Zhong, Z., Schreiber, R.D., Darnell, J.E. Jr & Murphy, K.M. (1995) Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. Journal of Experimental Medicine, 181, 1755.
    • (1995) Journal of Experimental Medicine , vol.181 , pp. 1755
    • Jacobson, N.G.1    Szabo, S.J.2    Weber-Nordt, R.M.3    Zhong, Z.4    Schreiber, R.D.5    Darnell Jr, J.E.6    Murphy, K.M.7
  • 45
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
    • Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A., Knop, J. & Enk, A.H. (2001) Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. Journal of Experimental Medicine, 193, 1285.
    • (2001) Journal of Experimental Medicine , vol.193 , pp. 1285
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3    Tuettenberg, A.4    Knop, J.5    Enk, A.H.6
  • 46
    • 0032535392 scopus 로고    scopus 로고
    • Critical requirement for graft passenger leukocytes in allograft tolerance induced by donor blood transfusion
    • Josien, R., Heslan, M., Brouard, S., Soulillou, J.P. & Cuturi, M.C. (1998) Critical requirement for graft passenger leukocytes in allograft tolerance induced by donor blood transfusion. Blood, 92, 4539.
    • (1998) Blood , vol.92 , pp. 4539
    • Josien, R.1    Heslan, M.2    Brouard, S.3    Soulillou, J.P.4    Cuturi, M.C.5
  • 48
    • 79959452615 scopus 로고    scopus 로고
    • STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis
    • Kaplan, M.H., Glosson, N.L., Stritesky, G.L., Yeh, N., Kinzfogl, J., Rohrabaugh, S.L. et al. (2011) STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis. Blood, 117, 6198.
    • (2011) Blood , vol.117 , pp. 6198
    • Kaplan, M.H.1    Glosson, N.L.2    Stritesky, G.L.3    Yeh, N.4    Kinzfogl, J.5    Rohrabaugh, S.L.6
  • 49
    • 0035908122 scopus 로고    scopus 로고
    • Subspecialization of CXCR5 +  T cells: B helper activity is focused in a germinal center-localized subset of CXCR5 +  T cells
    • Kim, C.H., Rott, L.S., Clark-Lewis, I., Campbell, D.J., Wu, L. & Butcher, E.C. (2001) Subspecialization of CXCR5 +  T cells: B helper activity is focused in a germinal center-localized subset of CXCR5 +  T cells. Journal of Experimental Medicine, 193, 1373.
    • (2001) Journal of Experimental Medicine , vol.193 , pp. 1373
    • Kim, C.H.1    Rott, L.S.2    Clark-Lewis, I.3    Campbell, D.J.4    Wu, L.5    Butcher, E.C.6
  • 50
    • 0033661042 scopus 로고    scopus 로고
    • Extracorporeal photochemotherapy-present and future
    • Knobler, R. (2000) Extracorporeal photochemotherapy-present and future. Vox Sanguinis, 78(Suppl 2), 197.
    • (2000) Vox Sanguinis , vol.78 , Issue.SUPPL 2 , pp. 197
    • Knobler, R.1
  • 52
    • 0037626590 scopus 로고    scopus 로고
    • Immune cell function testing: an adjunct to therapeutic drug monitoring in transplant patient management
    • Kowalski, R., Post, D., Schneider, M.C., Britz, J., Thomas, J., Deierhoi, M. et al. (2003) Immune cell function testing: an adjunct to therapeutic drug monitoring in transplant patient management. Clinical Transplantation, 17, 77.
    • (2003) Clinical Transplantation , vol.17 , pp. 77
    • Kowalski, R.1    Post, D.2    Schneider, M.C.3    Britz, J.4    Thomas, J.5    Deierhoi, M.6
  • 54
    • 58149300244 scopus 로고    scopus 로고
    • IL-33 induces antigen-specific IL-5 +  T cells and promotes allergic-induced airway inflammation independent of IL-4
    • Kurowska-Stolarska, M., Kewin, P., Murphy, G., Russo, R.C., Stolarski, B., Garcia, C.C. et al. (2008) IL-33 induces antigen-specific IL-5 +  T cells and promotes allergic-induced airway inflammation independent of IL-4. Journal of Immunology, 181, 4780.
    • (2008) Journal of Immunology , vol.181 , pp. 4780
    • Kurowska-Stolarska, M.1    Kewin, P.2    Murphy, G.3    Russo, R.C.4    Stolarski, B.5    Garcia, C.C.6
  • 55
    • 71749089605 scopus 로고    scopus 로고
    • Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors
    • Kwon, H., Thierry-Mieg, D., Thierry-Mieg, J., Kim, H.P., Oh, J., Tunyaplin, C. et al. (2009) Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. Immunity, 31, 941.
    • (2009) Immunity , vol.31 , pp. 941
    • Kwon, H.1    Thierry-Mieg, D.2    Thierry-Mieg, J.3    Kim, H.P.4    Oh, J.5    Tunyaplin, C.6
  • 57
    • 84860389694 scopus 로고    scopus 로고
    • The dynamic changes of Th17/Treg cytokines in rat liver transplant rejection and tolerance
    • Li, J., Lai, X., Liao, W., He, Y., Liu, Y. & Gong, J. (2011) The dynamic changes of Th17/Treg cytokines in rat liver transplant rejection and tolerance. International Immunopharmacology, 11, 962.
    • (2011) International Immunopharmacology , vol.11 , pp. 962
    • Li, J.1    Lai, X.2    Liao, W.3    He, Y.4    Liu, Y.5    Gong, J.6
  • 58
    • 77950349016 scopus 로고    scopus 로고
    • Th17 and regulatory T cells in mediating and restraining inflammation
    • Littman, D.R. & Rudensky, A.Y. (2010) Th17 and regulatory T cells in mediating and restraining inflammation. Cell, 140, 845.
    • (2010) Cell , vol.140 , pp. 845
    • Littman, D.R.1    Rudensky, A.Y.2
  • 59
    • 80755136623 scopus 로고    scopus 로고
    • Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells
    • Lu, K.T., Kanno, Y., Cannons, J.L., Handon, R., Bible, P., Elkahloun, A.G. et al. (2011) Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity, 35, 622.
    • (2011) Immunity , vol.35 , pp. 622
    • Lu, K.T.1    Kanno, Y.2    Cannons, J.L.3    Handon, R.4    Bible, P.5    Elkahloun, A.G.6
  • 60
    • 58749084519 scopus 로고    scopus 로고
    • Experimental extracorporeal photopheresis inhibits the sensitization and effector phases of contact hypersensitivity via two mechanisms: generation of IL-10 and induction of regulatory T cells
    • Maeda, A., Schwarz, A., Bullinger, A., Morita, A., Peritt, D. & Schwarz, T. (2008) Experimental extracorporeal photopheresis inhibits the sensitization and effector phases of contact hypersensitivity via two mechanisms: generation of IL-10 and induction of regulatory T cells. Journal of Immunology, 181, 5956.
    • (2008) Journal of Immunology , vol.181 , pp. 5956
    • Maeda, A.1    Schwarz, A.2    Bullinger, A.3    Morita, A.4    Peritt, D.5    Schwarz, T.6
  • 61
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy, K.J. & Powrie, F. (2001) Regulatory T cells in the control of immune pathology. Nature Immunology, 2, 816.
    • (2001) Nature Immunology , vol.2 , pp. 816
    • Maloy, K.J.1    Powrie, F.2
  • 66
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T.R., Cherwinski, H., Bond, M.W., Giedlin, M.A. & Coffman, R.L. (1986) Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. Journal of Immunology, 136, 2348.
    • (1986) Journal of Immunology , vol.136 , pp. 2348
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 67
    • 0036284984 scopus 로고    scopus 로고
    • The role of Th1/Th2 polarization in mucosal immunity
    • Neurath, M.F., Finotto, S. & Glimcher, L.H. (2002) The role of Th1/Th2 polarization in mucosal immunity. Nature Medicine, 8, 567.
    • (2002) Nature Medicine , vol.8 , pp. 567
    • Neurath, M.F.1    Finotto, S.2    Glimcher, L.H.3
  • 70
    • 84859487740 scopus 로고    scopus 로고
    • STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function
    • Nurieva, R.I., Podd, A., Chen, Y., Alekseev, A.M., Yu, M., Qi, X. et al. (2012) STAT5 protein negatively regulates T follicular helper (Tfh) cell generation and function. Journal of Biological Chemistry, 287, 11234.
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 11234
    • Nurieva, R.I.1    Podd, A.2    Chen, Y.3    Alekseev, A.M.4    Yu, M.5    Qi, X.6
  • 71
    • 35348876671 scopus 로고    scopus 로고
    • Influence of pretransplant panel-reactive antibody on outcomes in 8,160 heart transplant recipients in recent era
    • discussion 1562.
    • Nwakanma, L.U., Williams, J.A., Weiss, E.S., Russell, S.D., Baumgartner, W.A. & Conte, J.V. (2007) Influence of pretransplant panel-reactive antibody on outcomes in 8, 160 heart transplant recipients in recent era. Annals of Thoracic Surgery, 84, 1556; discussion 1562.
    • (2007) Annals of Thoracic Surgery , vol.84 , pp. 1556
    • Nwakanma, L.U.1    Williams, J.A.2    Weiss, E.S.3    Russell, S.D.4    Baumgartner, W.A.5    Conte, J.V.6
  • 73
    • 18144396852 scopus 로고    scopus 로고
    • Non-HLA transplantation immunity revealed by lymphocytotoxic antibodies
    • Opelz, G. (2005) Non-HLA transplantation immunity revealed by lymphocytotoxic antibodies. Lancet, 365, 1570.
    • (2005) Lancet , vol.365 , pp. 1570
    • Opelz, G.1
  • 74
    • 84866950561 scopus 로고    scopus 로고
    • Cyclosporine A enhances Th2 bias at the maternal-fetal interface in early human pregnancy with aid of the interaction between maternal and fetal cells
    • Piao, H.L., Wang, S.C., Tao, Y., Zhu, R., Sun, C., Fu, Q., Du, M.R. & Li, D.J. (2012) Cyclosporine A enhances Th2 bias at the maternal-fetal interface in early human pregnancy with aid of the interaction between maternal and fetal cells. PLoS ONE, 7, e45275.
    • (2012) PLoS ONE , vol.7
    • Piao, H.L.1    Wang, S.C.2    Tao, Y.3    Zhu, R.4    Sun, C.5    Fu, Q.6    Du, M.R.7    Li, D.J.8
  • 75
    • 0035421654 scopus 로고    scopus 로고
    • Cutting edge: control of CD8 +  T cell activation by CD4 + CD25 +  immunoregulatory cells
    • Piccirillo, C.A. & Shevach, E.M. (2001) Cutting edge: control of CD8 +  T cell activation by CD4 + CD25 +  immunoregulatory cells. Journal of Immunology, 167, 1137.
    • (2001) Journal of Immunology , vol.167 , pp. 1137
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 76
    • 34147134593 scopus 로고    scopus 로고
    • Transplant tolerance associated with a Th1 response and not broken by IL-4, IL-5, and TGF-beta blockade or Th1 cytokine administration
    • Plain, K.M., Boyd, R., Verma, N.D., Robinson, C.M., Tran, G.T., Hodgkinson, S.J. & Hall, B.M. (2007) Transplant tolerance associated with a Th1 response and not broken by IL-4, IL-5, and TGF-beta blockade or Th1 cytokine administration. Transplantation, 83, 764.
    • (2007) Transplantation , vol.83 , pp. 764
    • Plain, K.M.1    Boyd, R.2    Verma, N.D.3    Robinson, C.M.4    Tran, G.T.5    Hodgkinson, S.J.6    Hall, B.M.7
  • 77
    • 80053058970 scopus 로고    scopus 로고
    • B cells and TCR avidity determine distinct functions of CD4 +  T cells in retroviral infection
    • Ploquin, M.J., Eksmond, U. & Kassiotis, G. (2011) B cells and TCR avidity determine distinct functions of CD4 +  T cells in retroviral infection. Journal of Immunology, 187, 3321.
    • (2011) Journal of Immunology , vol.187 , pp. 3321
    • Ploquin, M.J.1    Eksmond, U.2    Kassiotis, G.3
  • 79
    • 84861209568 scopus 로고    scopus 로고
    • Maturation-related histone modifications in the PU.1 promoter regulate Th9-cell development
    • Ramming, A., Druzd, D., Leipe, J., Schulze-Koops, H. & Skapenko, A. (2012) Maturation-related histone modifications in the PU.1 promoter regulate Th9-cell development. Blood, 119, 4665.
    • (2012) Blood , vol.119 , pp. 4665
    • Ramming, A.1    Druzd, D.2    Leipe, J.3    Schulze-Koops, H.4    Skapenko, A.5
  • 80
    • 41549159660 scopus 로고    scopus 로고
    • Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
    • Rubtsov, Y.P., Rasmussen, J.P., Chi, E.Y., Fontenot, J., Castelli, L., Ye, X. et al. (2008) Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity, 28, 546.
    • (2008) Immunity , vol.28 , pp. 546
    • Rubtsov, Y.P.1    Rasmussen, J.P.2    Chi, E.Y.3    Fontenot, J.4    Castelli, L.5    Ye, X.6
  • 81
    • 0033608101 scopus 로고    scopus 로고
    • Intragraft cytokine expression and tolerance induction in rat renal allografts
    • Saggi, B.H., Fisher, R.A., Bu, D., Tawes, J.W., Riley, R. & Posner, M.P. (1999) Intragraft cytokine expression and tolerance induction in rat renal allografts. Transplantation, 67, 206.
    • (1999) Transplantation , vol.67 , pp. 206
    • Saggi, B.H.1    Fisher, R.A.2    Bu, D.3    Tawes, J.W.4    Riley, R.5    Posner, M.P.6
  • 82
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. & Toda, M. (1995) Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. Journal of Immunology, 155, 1151.
    • (1995) Journal of Immunology , vol.155 , pp. 1151
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 83
    • 0028077321 scopus 로고
    • IL-9 production of naive CD4 +  T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma
    • Schmitt, E., Germann, T., Goedert, S., Hoehn, P., Huels, C., Koelsch, S., Kuhn, R., Muller, W., Palm, N. & Rude, E. (1994) IL-9 production of naive CD4 +  T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma. Journal of Immunology, 153, 3989.
    • (1994) Journal of Immunology , vol.153 , pp. 3989
    • Schmitt, E.1    Germann, T.2    Goedert, S.3    Hoehn, P.4    Huels, C.5    Koelsch, S.6    Kuhn, R.7    Muller, W.8    Palm, N.9    Rude, E.10
  • 84
    • 84869863718 scopus 로고    scopus 로고
    • Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR(+)-Treg-cells in transplanted patients
    • Seissler, N., Schmitt, E., Hug, F., Sommerer, C., Zeier, M., Schaier, M. & Steinborn, A. (2012) Methylprednisolone treatment increases the proportion of the highly suppressive HLA-DR(+)-Treg-cells in transplanted patients. Transplant Immunology, 27, 157.
    • (2012) Transplant Immunology , vol.27 , pp. 157
    • Seissler, N.1    Schmitt, E.2    Hug, F.3    Sommerer, C.4    Zeier, M.5    Schaier, M.6    Steinborn, A.7
  • 86
    • 2942709797 scopus 로고    scopus 로고
    • Differential regulatory capacity of CD25 +  T regulatory cells and preactivated CD25 +  T regulatory cells on development, functional activation, and proliferation of Th2 cells
    • Stassen, M., Jonuleit, H., Muller, C., Klein, M., Richter, C., Bopp, T., Schmitt, S. & Schmitt, E. (2004) Differential regulatory capacity of CD25 +  T regulatory cells and preactivated CD25 +  T regulatory cells on development, functional activation, and proliferation of Th2 cells. Journal of Immunology, 173, 267.
    • (2004) Journal of Immunology , vol.173 , pp. 267
    • Stassen, M.1    Jonuleit, H.2    Muller, C.3    Klein, M.4    Richter, C.5    Bopp, T.6    Schmitt, S.7    Schmitt, E.8
  • 87
  • 88
    • 84869096853 scopus 로고    scopus 로고
    • Altered balance between effector T cells and FOXP3 +  HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients
    • Tang, Q., Leung, J., Melli, K., Lay, K., Chuu, E.L., Liu, W., Bluestone, J.A., Kang, S.M., Peddi, V.R. & Vincenti, F. (2012) Altered balance between effector T cells and FOXP3 +  HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients. Transplant International, 25, 1257.
    • (2012) Transplant International , vol.25 , pp. 1257
    • Tang, Q.1    Leung, J.2    Melli, K.3    Lay, K.4    Chuu, E.L.5    Liu, W.6    Bluestone, J.A.7    Kang, S.M.8    Peddi, V.R.9    Vincenti, F.10
  • 90
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells
    • Trifari, S., Kaplan, C.D., Tran, E.H., Crellin, N.K. & Spits, H. (2009) Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nature Immunology, 10, 864.
    • (2009) Nature Immunology , vol.10 , pp. 864
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3    Crellin, N.K.4    Spits, H.5
  • 91
    • 68649106176 scopus 로고    scopus 로고
    • Indefinite mouse heart allograft survival in recipient treated with CD4(+)CD25(+) regulatory T cells with indirect allospecificity and short term immunosuppression
    • Tsang, J.Y., Tanriver, Y., Jiang, S., Leung, E., Ratnasothy, K., Lombardi, G. & Lechler, R. (2009) Indefinite mouse heart allograft survival in recipient treated with CD4(+)CD25(+) regulatory T cells with indirect allospecificity and short term immunosuppression. Transplant Immunology, 21, 203.
    • (2009) Transplant Immunology , vol.21 , pp. 203
    • Tsang, J.Y.1    Tanriver, Y.2    Jiang, S.3    Leung, E.4    Ratnasothy, K.5    Lombardi, G.6    Lechler, R.7
  • 93
    • 46749115446 scopus 로고    scopus 로고
    • A fundamental role for interleukin-21 in the generation of T follicular helper cells
    • Vogelzang, A., McGuire, H.M., Yu, D., Sprent, J., Mackay, C.R. & King, C. (2008) A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity, 29, 127.
    • (2008) Immunity , vol.29 , pp. 127
    • Vogelzang, A.1    McGuire, H.M.2    Yu, D.3    Sprent, J.4    Mackay, C.R.5    King, C.6
  • 94
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Wan, Y.Y. & Flavell, R.A. (2007) Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature, 445, 766.
    • (2007) Nature , vol.445 , pp. 766
    • Wan, Y.Y.1    Flavell, R.A.2
  • 96
    • 0033783795 scopus 로고    scopus 로고
    • Switch from cyclosporine A to tacrolimus in renal transplant recipients: impact on Th1, Th2, and monokine responses
    • Weimer, R., Melk, A., Daniel, V., Friemann, S., Padberg, W. & Opelz, G. (2000) Switch from cyclosporine A to tacrolimus in renal transplant recipients: impact on Th1, Th2, and monokine responses. Human Immunology, 61, 884.
    • (2000) Human Immunology , vol.61 , pp. 884
    • Weimer, R.1    Melk, A.2    Daniel, V.3    Friemann, S.4    Padberg, W.5    Opelz, G.6
  • 98
    • 34247271308 scopus 로고    scopus 로고
    • Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
    • Williams, L.M. & Rudensky, A.Y. (2007) Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nature Immunology, 8, 277.
    • (2007) Nature Immunology , vol.8 , pp. 277
    • Williams, L.M.1    Rudensky, A.Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.