The dynamic changes of Th17/Treg cytokines in rat liver transplant rejection and tolerance

International Immunopharmacology

Volumn 11, Issue 8, 2011, Pages 962-967

  Li, Jinzheng ^a   Lai, Xing ^a   Liao, Wangyang ^a   He, Yong ^a   Liu, Yiming ^a   Gong, Jianping ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Th17 cells; Transplant immunity; Treg cells

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1;

ACUTE GRAFT REJECTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; GRAFT RECIPIENT; IMMUNOLOGICAL TOLERANCE; LIVER; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MALE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY T LYMPHOCYTE; SURVIVAL RATE; TH17 CELL; WESTERN BLOTTING;

EID: 84860389694     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.02.010     Document Type: Article

References (37)

1. O'Leary JG, Lepe R, Davis GL. Indications for liver transplantation. Gastroenterology 2008;134:1764-76. (Pubitemid 351615410)
2. Chen Y, Chen J, Liu Z, Liang S, Luan X, Long F, et al. Relationship between TH1/TH2 cytokines and immune tolerance in liver transplantation in rats. Transplant Proc 2008;40:2691-5.
3. Chen Y, Yan T, Shi LJ, Liu Z, Liang SY, Luan XF, et al. Knockdown of interleukin-2 by shRNA-mediated RNA interference prolongs liver allograft survival. J Surg Res 2010;159:582-7.
4. Weaver CT. Th17: the ascent of a new effector T-cell subset. Preface. Eur J Immunol 2009;39:634-6.
5. Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of T(H) 17 cells. Nature 2008;453:1051-7.
6. Weaver CT, Hatton RD. Interplay between the TH17 and TReg cell lineages: a (co-) evolutionary perspective. Nat Rev Immunol 2009;9:883-9.
7. Afzali B, Lombardi G, Lechler RI, Lord GM. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol 2007;148:32-46. (Pubitemid 46365005)
8. Hanidziar D, Koulmanda M. Inflammation and the balance of Treg and Th17 cells in transplant rejection and tolerance. Curr Opin Organ Transplant 2010;15:411-5.
9. Chen Y, Liu H, Liu Z, Liang S, Chen J, Long F, et al. Blockade of inducible costimulator pathway to prevent acute rejection in rat liver transplantation. Am J Surg 2009;198: 244-9.
10. Meyer D, Löffeler S, Otto C, Czub S, Gassel HJ, TimmermannW, et al. Donor-derived alloantigen-presenting cells persist in the liver allograft during tolerance induction. Transpl Int 2000;13:12-20. (Pubitemid 30417377)
11. Murase N, Starzl TE, Tanabe M, Fujisaki S, Miyazawa H, Ye Q, Demetris AJ, et al. Variable chimerism, graft-versus-host disease, and tolerance after different kinds of cell and whole organ transplantation from Lewis to brown Norway rats. Transplantation 1995;60:158-71.
12. Zimmermann FA, Davies HS, Knoll PP, Gokel JM, Schmidt T. Orthotopic liver allografts in the rat. The influence of strain combination on the fate of the graft. Transplantation 1984;37:406-10. (Pubitemid 14105436)
13. Demetris AJ, Batts KP, Dhillon AP, Ferrell L, Fung J, Geller SA, et al. Banff schema for grading liver allograft rejection: an international consensus document. Hepatology 1997;25:658-63. (Pubitemid 27106450)
14. Höroldt BS, Burattin M, Gunson BK, Bramhall SR, Nightingale P, Hübscher SG, et al. Does the Banff rejection activity index predict outcome in patients with early acute cellular rejection following liver transplantation? Liver Transpl 2006;12:1144-51. (Pubitemid 44063791)
15. Knechtle SJ, Kwun J. Unique aspects of rejection and tolerance in liver transplantation. Semin Liver Dis 2009;29:91-101.
16. Crispe IN. The liver as a lymphoid organ. Annu Rev Immunol 2009;27:147-63.
17. Wing K, Sakaguchi S. Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat Immunol 2010;11:7-13.
18. Bettini M, Vignali DA. Regulatory T cells and inhibitory cytokines in autoimmunity. Curr Opin Immunol 2009;21:612-8.
19. Xia G, ShahM, Luo X. Prevention of allograft rejection by amplification of Foxp3(+) CD4(+)CD25(+) regulatory T cells. Transl Res 2009;153:60-70.
20. Long E, Wood KJ. Regulatory T cells in transplantation: transferring mouse studies to the clinic. Transplantation 2009;88:1050-6.
21. Coombes JL, Maloy KJ. Control of intestinal homeostasis by regulatory T cells and dendritic cells. Semin Immunol 2007;19:116-26. (Pubitemid 46810287)
22. Xystrakis E, Urry Z, Hawrylowicz CM. Regulatory T cell therapy as individualized medicine for asthma and allergy. Curr Opin Allergy Clin Immunol 2007;7:535-41. (Pubitemid 350076450)
23. Abe Y, Urakami H, Ostanin D, Zibari G, Hayashida T, Kitagawa Y, et al. Induction of Foxp3-expressing regulatory T-cells by donor blood transfusion is required for tolerance to rat liver allografts. PLoS ONE 2009;4:e7840.
24. Li W, Kuhr CS, Zheng XX, Carper K, Thomson AW, Reyes JD, et al. New insights into mechanisms of spontaneous liver transplant tolerance: the role of Foxp3-expressing CD25+CD4+ regulatory T cells. Am J Transplant 2008;8:1639-51.
25. Vignali DA, Collison LW, Workman CJ. How regulatory T cellswork.Nat Rev Immunol 2008;8:523-32.
26. Leung S, Liu X, Fang L, Chen X, Guo T, Zhang J. The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease. Cell Mol Immunol 2010;7:182-9.
27. Lee YK, Turner H, Maynard CL, Oliver JR, Chen D, Elson CO, et al. Late developmental plasticity in the T helper 17 lineage. Immunity 2009;30:92-107.
28. Korn T, Bettelli E, Oukka M, Kuchroo VK. IL-17 and Th17 cells. Annu Rev Immunol 2009;27:485-517.
29. Peck A, Mellins ED. Breaking old paradigms: Th17 cells in autoimmune arthritis. Clin Immunol 2009;132:295-304.
30. Nalbandian A, Crispín JC, Tsokos GC. Interleukin-17 and systemic lupus erythematosus: current concepts. Clin Exp Immunol 2009;157:209-15.
31. Darlington PJ, Boivin MN, Renoux C, François M, Galipeau J, Freedman MS, et al. Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: implication for multiple sclerosis. Ann Neurol 2010;68:540-5.
32. Miossec P. IL-17 and Th17 cells in human inflammatory diseases. Microbes Infect 2009;11:625-30.
33. Fábrega E, López-Hoyos M, San Segundo D, Casafont F, Pons-Romero F. Changes in the serum levels of interleukin-17/interleukin-23 during acute rejection in liver transplantation. Liver Transpl 2009;15:629-33.
34. Loong CC, Hsieh HG, Lui WY, Chen A, Lin CY. Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection. J Pathol 2002;197:322-32. (Pubitemid 34778302)
35. Li J, Simeoni E, Fleury S, Dudler J, Fiorini E, Kappenberger L, et al. Gene transfer of soluble interleukin-17 receptor prolongs cardiac allograft survival in a rat model. Eur J Cardiothorac Surg 2006;29:779-83.
36. Vanaudenaerde BM, Dupont LJ, Wuyts WA, Verbeken EK, Meyts I, Bullens DM, et al. The role of interleukin-17 during acute rejection after lung transplantation. Eur Respir J 2006;27:779-87. (Pubitemid 44914203)
37. Yoshida S, Haque A, Mizobuchi T, Iwata T, Chiyo M, Webb TJ, et al. Anti-type V collagen lymphocytes that express IL-17 and IL-23 induce rejection pathology in fresh and well-healed lung transplants. Am J Transplant 2006;6:724-35. (Pubitemid 43345010)