-
1
-
-
0042932806
-
Molecular phylogeny within type I cytokines and their cognate receptors
-
Boulay JL, O'Shea JJ, Paul WE. Molecular phylogeny within type I cytokines and their cognate receptors. Immunity 2003; 19:159-163.
-
(2003)
Immunity
, vol.19
, pp. 159-163
-
-
Boulay, J.L.1
O'Shea, J.J.2
Paul, W.E.3
-
2
-
-
33845606612
-
IL-12p40: An inherently agonistic cytokine
-
Cooper AM, Khader SA. IL-12p40: an inherently agonistic cytokine. Trends Immunol 2007; 28:33-38.
-
(2007)
Trends Immunol
, vol.28
, pp. 33-38
-
-
Cooper, A.M.1
Khader, S.A.2
-
3
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 2003; 3:133-146.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
4
-
-
34247523141
-
-
Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu Rev Immunol 2007; 25:221-242. A comprehensive review on IL-23 and IL-27 biology.
-
Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu Rev Immunol 2007; 25:221-242. A comprehensive review on IL-23 and IL-27 biology.
-
-
-
-
5
-
-
33847206969
-
IL-17 family cytokines and the expanding diversity of effector T cell lineages
-
Weaver CT, Hatton RD, Mangan PR, Harrington LE. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 2007; 25:821-852.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 821-852
-
-
Weaver, C.T.1
Hatton, R.D.2
Mangan, P.R.3
Harrington, L.E.4
-
6
-
-
33748588423
-
The orphan nuclear receptor ROR-gammat directs the differentiation program of proinflammatory IL-17(+) T helper cells
-
Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor ROR-gammat directs the differentiation program of proinflammatory IL-17(+) T helper cells. Cell 2006; 126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
-
7
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
8
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB, et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006; 441:231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
-
9
-
-
34547204946
-
Essential autocrine regulation by IL-21 in the generation of inflammatory T cells
-
Nurieva R, Yang XO, Martinez G, et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007; 448:480-483.
-
(2007)
Nature
, vol.448
, pp. 480-483
-
-
Nurieva, R.1
Yang, X.O.2
Martinez, G.3
-
10
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn T, Bettelli E,Gao W, et al. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007; 448:484-487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
-
11
-
-
34547188748
-
-
Zhou L, Ivanov II, Spolski R, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007; 8:967-974. This paper analyzes the contribution of TGF-β, IL-6, IL-21 and IL-23 in Th17 development.
-
Zhou L, Ivanov II, Spolski R, et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007; 8:967-974. This paper analyzes the contribution of TGF-β, IL-6, IL-21 and IL-23 in Th17 development.
-
-
-
-
12
-
-
34249079176
-
-
Acosta-Rodriguez EV, Rivino L, Geginat J, et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007; 8:639-646. This article, together with Ref. [13*], characterizes the phenotype and cytokine requirement of human Th17 cells.
-
Acosta-Rodriguez EV, Rivino L, Geginat J, et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007; 8:639-646. This article, together with Ref. [13*], characterizes the phenotype and cytokine requirement of human Th17 cells.
-
-
-
-
13
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato F, Cosmi L, Santarlasci V, et al. Phenotypic and functional features of human Th17 cells. J Exp Med 2007; 204:1849-1861.
-
(2007)
J Exp Med
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
-
14
-
-
36348980530
-
Absence of regulatory T cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft versus host disease
-
Chen X, Vodanovic-Jankovic S, Johnson B, et al. Absence of regulatory T cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft versus host disease. Blood 2007; 110:3804-3813.
-
(2007)
Blood
, vol.110
, pp. 3804-3813
-
-
Chen, X.1
Vodanovic-Jankovic, S.2
Johnson, B.3
-
15
-
-
34249026701
-
Sousa: Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
-
Leibundgut-Landmann S, Gross O, Robinson MJ, et al. Sousa: Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol 2007; 8:630-638.
-
(2007)
Nat Immunol
, vol.8
, pp. 630-638
-
-
Leibundgut-Landmann, S.1
Gross, O.2
Robinson, M.J.3
-
16
-
-
35348948374
-
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells
-
van Beelen AJ, Zelinkova Z, Taanman-Kueter EW, et al. Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity 2007; 27:660-669.
-
(2007)
Immunity
, vol.27
, pp. 660-669
-
-
van Beelen, A.J.1
Zelinkova, Z.2
Taanman-Kueter, E.W.3
-
17
-
-
34250184097
-
The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23->IL-17 axis
-
Sheibanie AF, Yen JH, Khayrullina T, et al. The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23->IL-17 axis. J Immunol 2007; 178:8138-8147.
-
(2007)
J Immunol
, vol.178
, pp. 8138-8147
-
-
Sheibanie, A.F.1
Yen, J.H.2
Khayrullina, T.3
-
18
-
-
9444244401
-
Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells
-
Sheibanie AF, Tadmori I, Jing H, et al. Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells. FASEB J 2004; 18:1318-1320.
-
(2004)
FASEB J
, vol.18
, pp. 1318-1320
-
-
Sheibanie, A.F.1
Tadmori, I.2
Jing, H.3
-
19
-
-
13544251389
-
Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: A novel role for the cAMP pathway
-
Schnurr M, Toy T, Shin A, et al. Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway. Blood 2005; 105:1582-1589.
-
(2005)
Blood
, vol.105
, pp. 1582-1589
-
-
Schnurr, M.1
Toy, T.2
Shin, A.3
-
20
-
-
0037114150
-
IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: Evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination
-
Gran B, Zhang GX, Yu S, et al. IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination. J Immunol 2002; 169:7104-7110.
-
(2002)
J Immunol
, vol.169
, pp. 7104-7110
-
-
Gran, B.1
Zhang, G.X.2
Yu, S.3
-
21
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua DJ, Sherlock J, Chen Y, et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003; 421:744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
-
22
-
-
33748294322
-
Role of IFN-gamma in induction of Foxp3 and conversion of CD4+
-
Wang Z, Hong J, Sun W, et al. Role of IFN-gamma in induction of Foxp3 and conversion of CD4+. J Clin Invest 2006; 116:2434-2441.
-
(2006)
J Clin Invest
, vol.116
, pp. 2434-2441
-
-
Wang, Z.1
Hong, J.2
Sun, W.3
-
23
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6:1123-1132.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
24
-
-
22344434572
-
IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
-
Sawitzki B, Kingsley CI, Oliveira V, et al. IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo. J Exp Med 2005; 201:1925-1935.
-
(2005)
J Exp Med
, vol.201
, pp. 1925-1935
-
-
Sawitzki, B.1
Kingsley, C.I.2
Oliveira, V.3
-
25
-
-
33645878295
-
Interferon gamma: A crucial role in the function of induced regulatory T cells in vivo
-
This article highlights the immunoregulatory role of IFN-γ in the context of organ transplantation
-
Wood KJ, Sawitzki B. Interferon gamma: a crucial role in the function of induced regulatory T cells in vivo. Trends Immunol 2006; 27:183-187. This article highlights the immunoregulatory role of IFN-γ in the context of organ transplantation.
-
(2006)
Trends Immunol
, vol.27
, pp. 183-187
-
-
Wood, K.J.1
Sawitzki, B.2
-
26
-
-
0030240073
-
IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection: Evidence against a dominant protective role for T helper 2 cytokines in alloimmunity
-
Piccotti JR, Chan SY, Goodman RE, et al. IL-12 antagonism induces T helper 2 responses, yet exacerbates cardiac allograft rejection: evidence against a dominant protective role for T helper 2 cytokines in alloimmunity. J Immunol 1996; 157:1951-1957.
-
(1996)
J Immunol
, vol.157
, pp. 1951-1957
-
-
Piccotti, J.R.1
Chan, S.Y.2
Goodman, R.E.3
-
27
-
-
33751504317
-
-
Verma ND, Boyd R, Robinson C, et al. Interleukin-12p70 prolongs allograft survival by induction of interferon gamma and nitric oxide production. Transplantation 2006; 82:1324-1333. This paper shows that IL-12p70 can inhibit rejection through induction of IFN-γ and iNOS.
-
Verma ND, Boyd R, Robinson C, et al. Interleukin-12p70 prolongs allograft survival by induction of interferon gamma and nitric oxide production. Transplantation 2006; 82:1324-1333. This paper shows that IL-12p70 can inhibit rejection through induction of IFN-γ and iNOS.
-
-
-
-
28
-
-
0032079469
-
Interleukin-12 inhibits graft-versus-host disease through a Fas-mediated mechanism associated with alterations in donor T-cell activation and expansion
-
Dey BR, Yang YG, Szot GL, et al. Interleukin-12 inhibits graft-versus-host disease through a Fas-mediated mechanism associated with alterations in donor T-cell activation and expansion. Blood 1998; 91:3315-3322.
-
(1998)
Blood
, vol.91
, pp. 3315-3322
-
-
Dey, B.R.1
Yang, Y.G.2
Szot, G.L.3
-
29
-
-
34648846165
-
Cellular mechanisms underlying acute graft rejection: Time for reassessment
-
This article discusses the different pathways underlying acute graft rejection
-
Alegre ML, Florquin S, Goldman M. Cellular mechanisms underlying acute graft rejection: time for reassessment. Curr Opin Immunol 2007; 19:563-568. This article discusses the different pathways underlying acute graft rejection.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 563-568
-
-
Alegre, M.L.1
Florquin, S.2
Goldman, M.3
-
30
-
-
0344457228
-
Evidence for a role of IL-17 in alloimmunity: A novel IL-17 antagonist promotes heart graft survival
-
Antonysamy MA, Fanslow WC, Fu F, et al. Evidence for a role of IL-17 in alloimmunity: a novel IL-17 antagonist promotes heart graft survival. Transplant Proc 1999; 31:93.
-
(1999)
Transplant Proc
, vol.31
, pp. 93
-
-
Antonysamy, M.A.1
Fanslow, W.C.2
Fu, F.3
-
31
-
-
0034898588
-
Interleukin-17 antagonism inhibits acute but not chronic vascular rejection
-
Tang JL, Subbotin VM, Antonysamy MA, et al. Interleukin-17 antagonism inhibits acute but not chronic vascular rejection. Transplantation 2001; 72:348-350.
-
(2001)
Transplantation
, vol.72
, pp. 348-350
-
-
Tang, J.L.1
Subbotin, V.M.2
Antonysamy, M.A.3
-
32
-
-
0031903820
-
Interleukin-17 activates human renal epithelial cells in vitro and is expressed during renal allograft rejection
-
Van Kooten C, Boonstra JG, Paape ME, et al. Interleukin-17 activates human renal epithelial cells in vitro and is expressed during renal allograft rejection. J Am Soc Nephrol 1998; 9:1526-1534.
-
(1998)
J Am Soc Nephrol
, vol.9
, pp. 1526-1534
-
-
Van Kooten, C.1
Boonstra, J.G.2
Paape, M.E.3
-
33
-
-
33748286452
-
The role of interleukin-17 during acute rejection after lung transplantation
-
Vanaudenaerde BM, Dupont LJ, Wuyts WA, et al. The role of interleukin-17 during acute rejection after lung transplantation. Eur Respir J 2006; 27:779-787.
-
(2006)
Eur Respir J
, vol.27
, pp. 779-787
-
-
Vanaudenaerde, B.M.1
Dupont, L.J.2
Wuyts, W.A.3
-
34
-
-
33644762252
-
Antitype V collagen lymphocytes that express IL-17 and IL-23 induce rejection pathology in fresh and well healed lung transplants
-
Yoshida S, Haque A, Mizobuchi T, et al. Antitype V collagen lymphocytes that express IL-17 and IL-23 induce rejection pathology in fresh and well healed lung transplants. Am J Transplant 2006; 6:724-735.
-
(2006)
Am J Transplant
, vol.6
, pp. 724-735
-
-
Yoshida, S.1
Haque, A.2
Mizobuchi, T.3
-
35
-
-
33749515631
-
Two-sided roles of IL-27: Induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism
-
Yoshimura T, Takeda A, Hamano S, et al. Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism. J Immunol 2006; 177:5377-5385.
-
(2006)
J Immunol
, vol.177
, pp. 5377-5385
-
-
Yoshimura, T.1
Takeda, A.2
Hamano, S.3
-
36
-
-
0344304399
-
IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms
-
Lucas S, Ghilardi N, Li J, de Sauvage FJ. IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms. Proc Natl Acad Sci U S A 2003; 100:15047-15052.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15047-15052
-
-
Lucas, S.1
Ghilardi, N.2
Li, J.3
de Sauvage, F.J.4
-
37
-
-
0345570521
-
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
-
Villarino A, Hibbert L, Lieberman L, et al. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 2003; 19:645-655.
-
(2003)
Immunity
, vol.19
, pp. 645-655
-
-
Villarino, A.1
Hibbert, L.2
Lieberman, L.3
-
38
-
-
30344488706
-
Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology
-
Rosas LE, Satoskar AA, Roth KM, et al. Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology. Am J Pathol 2006; 168:158-169.
-
(2006)
Am J Pathol
, vol.168
, pp. 158-169
-
-
Rosas, L.E.1
Satoskar, A.A.2
Roth, K.M.3
-
39
-
-
14844355133
-
The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis
-
Holscher C, Holscher A, Ruckerl D, et al. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J Immunol 2005; 174:3534-3544.
-
(2005)
J Immunol
, vol.174
, pp. 3534-3544
-
-
Holscher, C.1
Holscher, A.2
Ruckerl, D.3
-
40
-
-
2942564059
-
WSX-1: A key role in induction of chronic intestinal nematode infection
-
Bancroft AJ, Humphreys NE, Worthington JJ, et al. WSX-1: a key role in induction of chronic intestinal nematode infection. J Immunol 2004; 172:7635-7641.
-
(2004)
J Immunol
, vol.172
, pp. 7635-7641
-
-
Bancroft, A.J.1
Humphreys, N.E.2
Worthington, J.J.3
-
41
-
-
23444445743
-
Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice
-
Miyazaki Y, Inoue H, Matsumura M, et al. Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice. J Immunol 2005; 175:2401-2407.
-
(2005)
J Immunol
, vol.175
, pp. 2401-2407
-
-
Miyazaki, Y.1
Inoue, H.2
Matsumura, M.3
-
42
-
-
38149045608
-
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: A novel therapeutic way for Th2-mediated allergic inflammation
-
Yoshimoto T, Yoshimoto T, Yasuda K, et al. IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. J Immunol 2007; 179:4415-4423.
-
(2007)
J Immunol
, vol.179
, pp. 4415-4423
-
-
Yoshimoto, T.1
Yoshimoto, T.2
Yasuda, K.3
-
43
-
-
33747588291
-
-
Batten M, Li J, Yi S, et al. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol 2006; 7:929-936. Together with the article here below, this study demonstrates that IL-27 negatively regulate Th17 development.
-
Batten M, Li J, Yi S, et al. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol 2006; 7:929-936. Together with the article here below, this study demonstrates that IL-27 negatively regulate Th17 development.
-
-
-
-
44
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer JS, Laurence A, Wilson EH, et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol 2006; 7:937-945.
-
(2006)
Nat Immunol
, vol.7
, pp. 937-945
-
-
Stumhofer, J.S.1
Laurence, A.2
Wilson, E.H.3
-
45
-
-
35648988381
-
Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis
-
Fitzgerald DC, Ciric B, Touil T, et al. Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis. J Immunol 2007; 179:3268-3275.
-
(2007)
J Immunol
, vol.179
, pp. 3268-3275
-
-
Fitzgerald, D.C.1
Ciric, B.2
Touil, T.3
-
46
-
-
34250005444
-
T(H)17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1
-
Amadi-Obi A, Yu CR, Liu X, et al. T(H)17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1. Nat Med 2007; 13:711-718.
-
(2007)
Nat Med
, vol.13
, pp. 711-718
-
-
Amadi-Obi, A.1
Yu, C.R.2
Liu, X.3
-
47
-
-
33746931178
-
-
Wirtz S, Tubbe I, Galle PR, et al. Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27. J Exp Med 2006; 203:1875-1881. This paper indicates that IL-27 contributes to the regulation of neutrophil-mediated inflammation.
-
Wirtz S, Tubbe I, Galle PR, et al. Protection from lethal septic peritonitis by neutralizing the biological function of interleukin 27. J Exp Med 2006; 203:1875-1881. This paper indicates that IL-27 contributes to the regulation of neutrophil-mediated inflammation.
-
-
-
-
48
-
-
34447567140
-
IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1
-
Neufert C, Becker C, Wirtz S, et al. IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1. Eur J Immunol 2007; 37:1809-1816.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1809-1816
-
-
Neufert, C.1
Becker, C.2
Wirtz, S.3
-
49
-
-
0030700003
-
Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin
-
Devergne O, Birkenbach M, Kieff E. Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin. Proc Natl Acad Sci U S A 1997; 94:12041-12046.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 12041-12046
-
-
Devergne, O.1
Birkenbach, M.2
Kieff, E.3
-
50
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
Gavin MA, Rasmussen JP, Fontenot JD, et al. Foxp3-dependent programme of regulatory T-cell differentiation. Nature 2007; 445:771-775.
-
(2007)
Nature
, vol.445
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
-
51
-
-
36549030784
-
-
Collison LW, Workman CJ, Kuo TT, et al. The inhibitory cytokine IL-35 contributes to regulatory T cell function. Nature 2007; 450:566-569. This article identifies EBI3/p35 heterodimer as an important soluble mediator of Treg function.
-
Collison LW, Workman CJ, Kuo TT, et al. The inhibitory cytokine IL-35 contributes to regulatory T cell function. Nature 2007; 450:566-569. This article identifies EBI3/p35 heterodimer as an important soluble mediator of Treg function.
-
-
-
-
52
-
-
36248970671
-
-
Niedbala W, Wei XQ, Cai B, et al. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. Eur J Immunol 2007; 37:3021-3029. This article demonstrates that recombinant IL-35 has antiinflammatory properties in collagen-induced arthritis.
-
Niedbala W, Wei XQ, Cai B, et al. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. Eur J Immunol 2007; 37:3021-3029. This article demonstrates that recombinant IL-35 has antiinflammatory properties in collagen-induced arthritis.
-
-
-
-
53
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer JS, Silver JS, Laurence A, et al. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol 2007; 8:1363-1371.
-
(2007)
Nat Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
-
54
-
-
36248970702
-
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
-
Fitzgerald DC, Zhang GX, EI Behi M, et al. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat Immunol 2007; 8:1372-1379.
-
(2007)
Nat Immunol
, vol.8
, pp. 1372-1379
-
-
Fitzgerald, D.C.1
Zhang, G.X.2
EI Behi, M.3
-
55
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
-
Awasthi A, Carrier Y, Peron JP, et al. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat Immunol 2007; 8:1380-1389.
-
(2007)
Nat Immunol
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
Carrier, Y.2
Peron, J.P.3
|