Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice

Biochemical Pharmacology

Volumn 89, Issue 3, 2014, Pages 399-412

  Spruiell, Krisstonia ^a   Jones, Dominique Z ^a   Cullen, John M ^b   Awumey, Emmanuel M ^a   Gonzalez, Frank J ^c   Gyamfi, Maxwell A ^a  

^a NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Females; High fat diet; Nuclear receptors; Obesity; Pregnane X receptor; Type 2 diabetes

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA TUBULIN; CHOLESTEROL; CYTOCHROME P450 3A11; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; GLUCOKINASE; GLUCOSE 6 PHOSPHATASE; INSULIN; LEPTIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PREGNANE X RECEPTOR; TRIACYLGLYCEROL; UNCOUPLING PROTEIN 1;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HYPERINSULINEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; LIPID DIET; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OBESITY; PREMENOPAUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; WHITE ADIPOSE TISSUE;

FEMALES; HIGH-FAT DIET; NUCLEAR RECEPTORS; OBESITY; PREGNANE X RECEPTOR; TYPE 2 DIABETES;

ADIPOSE TISSUE, WHITE; ANIMALS; BLOOD GLUCOSE; CYTOCHROME P-450 CYP3A; DIETARY FATS; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE INTOLERANCE; HUMANS; ION CHANNELS; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MITOCHONDRIAL PROTEINS; OBESITY; RECEPTORS, STEROID;

EID: 84899918513     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.03.019     Document Type: Article

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