P50-associated COX-2 Extragenic RNA (pacer) activates human COX-2 gene expression by occluding repressive NF-κB p50 complexes

eLife

Volumn 2014, Issue 3, 2014, Pages

  Krawczyk, Michal ^a   Emerson, Beverly M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Anti sense transcripts; Cancer; CTCF; Cyclooxygenase 2; Divergent promoters; Histone acetylation; Long non coding RNA; Monocyte macrophage differentiation; NF B; P300; RNA polymerase II recruitment; Transcription

Indexed keywords

CYCLOOXYGENASE 2; DNA POLYMERASE; E1A ASSOCIATED P300 PROTEIN; HISTONE ACETYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LONG UNTRANSLATED RNA; MESSENGER RNA; PROTEIN P50; RNA POLYMERASE II; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TAQ POLYMERASE; TRANSCRIPTION FACTOR CTCF; PTGS2 PROTEIN, HUMAN; UNTRANSLATED RNA;

ARTICLE; CARCINOGENESIS; CELL FRACTIONATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE SILENCING; GENETIC CODE; GENETIC TRANSCRIPTION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PURIFICATION; TRANSCRIPTION INITIATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL CULTURE; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MONOCYTE; PHYSIOLOGY;

CELLS, CULTURED; CYCLOOXYGENASE 2; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; MONOCYTES; NF-KAPPA B P50 SUBUNIT; RNA, UNTRANSLATED; TRANSCRIPTION, GENETIC;

EID: 84899894457     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.01776     Document Type: Article

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