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Volumn 65, Issue 5, 2005, Pages 1792-1799

p38 regulates cyclooxygenase-2 in human mammary epithelial cells and is activated in premalignant tissue

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

EID: 16444386879     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-3507     Document Type: Article
Times cited : (48)

References (41)
  • 2
    • 0026611230 scopus 로고
    • Prostaglandin E1, E2, and F2α in human milk and plasma
    • Shimizu T, Yamashiro Y, Yabuta K. Prostaglandin E1, E2, and F2α in human milk and plasma. Biol Neonate 1992;61:222-5.
    • (1992) Biol Neonate , vol.61 , pp. 222-225
    • Shimizu, T.1    Yamashiro, Y.2    Yabuta, K.3
  • 3
    • 0032588218 scopus 로고    scopus 로고
    • Cytokines (IL-1β, IL-6, TNF-α, TGF-β1, and TGF-β2) and prostaglandin E2 in human milk during the first three months postpartum
    • Hawkes JS, Bryan DL, James MJ, Gibson RA. Cytokines (IL-1β, IL-6, TNF-α, TGF-β1, and TGF-β2) and prostaglandin E2 in human milk during the first three months postpartum. Pediatr Res 1999;46:194-9.
    • (1999) Pediatr Res , vol.46 , pp. 194-199
    • Hawkes, J.S.1    Bryan, D.L.2    James, M.J.3    Gibson, R.A.4
  • 4
    • 0035798579 scopus 로고    scopus 로고
    • The transcription factor C/EBPβ is essential for inducible expression of the cox-2 gene in macrophages but not in fibroblasts
    • Gorgoni B, Caivano M, Arizmendi C, Poli V. The transcription factor C/EBPβ is essential for inducible expression of the cox-2 gene in macrophages but not in fibroblasts. J Biol Chem 2001;276:40769-77.
    • (2001) J Biol Chem , vol.276 , pp. 40769-40777
    • Gorgoni, B.1    Caivano, M.2    Arizmendi, C.3    Poli, V.4
  • 5
    • 0141844522 scopus 로고    scopus 로고
    • Regulation of cyclooxgenase-2 mRNA stability by taxanes: Evidence for involvement of p38, MAPKAPK-2, and HuR
    • Subbaramaiah K, Marmo TP, Dixon DA, Dannenberg AJ. Regulation of cyclooxgenase-2 mRNA stability by taxanes: evidence for involvement of p38, MAPKAPK-2, and HuR. J Biol Chem 2003;278:37637-47.
    • (2003) J Biol Chem , vol.278 , pp. 37637-37647
    • Subbaramaiah, K.1    Marmo, T.P.2    Dixon, D.A.3    Dannenberg, A.J.4
  • 7
    • 0036157485 scopus 로고    scopus 로고
    • Many actions of cyclooxygenase-2 in cellular dynamics and in cancer
    • Cao Y, Prescott SM. Many actions of cyclooxygenase-2 in cellular dynamics and in cancer. J Cell Physiol 2002;190:279-86.
    • (2002) J Cell Physiol , vol.190 , pp. 279-286
    • Cao, Y.1    Prescott, S.M.2
  • 8
    • 0036440486 scopus 로고    scopus 로고
    • Role of cyclooxygenase-2 in breast cancer
    • Singh B, Lucci A. Role of cyclooxygenase-2 in breast cancer. J Surg Res 2002;108:173-9.
    • (2002) J Surg Res , vol.108 , pp. 173-179
    • Singh, B.1    Lucci, A.2
  • 9
    • 0036468899 scopus 로고    scopus 로고
    • Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer
    • Ristimaki A, Sivula A, Lundin J, et al. Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer. Cancer Res 2002;62:632-5.
    • (2002) Cancer Res , vol.62 , pp. 632-635
    • Ristimaki, A.1    Sivula, A.2    Lundin, J.3
  • 10
    • 0038010530 scopus 로고    scopus 로고
    • Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma
    • Denkert C, Winzer KJ, Muller BM, et al. Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma. Cancer 2003;97:2978-87.
    • (2003) Cancer , vol.97 , pp. 2978-2987
    • Denkert, C.1    Winzer, K.J.2    Muller, B.M.3
  • 11
    • 0037463230 scopus 로고    scopus 로고
    • Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival
    • Spizzo G, Gastl G, Wolf D, et al. Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival. Br J Cancer 2003;88:574-8.
    • (2003) Br J Cancer , vol.88 , pp. 574-578
    • Spizzo, G.1    Gastl, G.2    Wolf, D.3
  • 12
    • 0037086261 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ
    • Half E, Tang XM, Gwyn K, Sahin A, Wathen K, Sinicrope F. Cyclooxygenase-2 expression in human breast cancers and adjacent ductal carcinoma in situ. Cancer Res 2002;62:1676-81.
    • (2002) Cancer Res , vol.62 , pp. 1676-1681
    • Half, E.1    Tang, X.M.2    Gwyn, K.3    Sahin, A.4    Wathen, K.5    Sinicrope, F.6
  • 13
    • 0042074576 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 in malignant and benign breast tumors
    • Watanabe O, Shimizu T, Imamura H, et al. Expression of cyclooxygenase-2 in malignant and benign breast tumors. Anticancer Res 2003;23:3215-21.
    • (2003) Anticancer Res , vol.23 , pp. 3215-3221
    • Watanabe, O.1    Shimizu, T.2    Imamura, H.3
  • 14
    • 0034671806 scopus 로고    scopus 로고
    • COX-2 is expressed in human pulmonary, colonic, and mammary tumors
    • Soslow RA, Dannenberg AJ, Rush D, et al. COX-2 is expressed in human pulmonary, colonic, and mammary tumors. Cancer 2000;89:2637-45.
    • (2000) Cancer , vol.89 , pp. 2637-2645
    • Soslow, R.A.1    Dannenberg, A.J.2    Rush, D.3
  • 15
    • 0038182606 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium
    • Shim V, Gauthier ML, Sudilovsky D, et al. Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium. Cancer Res 2003;63:2347-50.
    • (2003) Cancer Res , vol.63 , pp. 2347-2350
    • Shim, V.1    Gauthier, M.L.2    Sudilovsky, D.3
  • 16
    • 1342301548 scopus 로고    scopus 로고
    • COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ
    • Boland GP, Butt IS, Prasad R, Knox WF, Bundred NJ. COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ. Br J Cancer 2004;90:423-9.
    • (2004) Br J Cancer , vol.90 , pp. 423-429
    • Boland, G.P.1    Butt, I.S.2    Prasad, R.3    Knox, W.F.4    Bundred, N.J.5
  • 17
    • 1642503735 scopus 로고    scopus 로고
    • Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program
    • Crawford YG, Gauthier ML, Joubel A, et al. Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program. Cancer Cell 2004;5:263-73.
    • (2004) Cancer Cell , vol.5 , pp. 263-273
    • Crawford, Y.G.1    Gauthier, M.L.2    Joubel, A.3
  • 18
    • 0035252089 scopus 로고    scopus 로고
    • Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
    • Romanov SR, Kozalkiewicz BK, Holst CR, Stampfer MR, Haupt LM, Tlsty TD. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 2001;409:633-7.
    • (2001) Nature , vol.409 , pp. 633-637
    • Romanov, S.R.1    Kozalkiewicz, B.K.2    Holst, C.R.3    Stampfer, M.R.4    Haupt, L.M.5    Tlsty, T.D.6
  • 19
    • 0345178412 scopus 로고
    • Serum-free growth of human mammary epithelial cells: Rapid clonal growth in defined medium and extended serial passage with pituitary extract
    • Hammond SL, Ham RG, Stampfer MR. Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract. Proc Natl Acad Sci U S A 1984;81:5435-9.
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 5435-5439
    • Hammond, S.L.1    Ham, R.G.2    Stampfer, M.R.3
  • 20
    • 0034685876 scopus 로고    scopus 로고
    • Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 and p38 mitogen-activated protein kinase pathways
    • Subbaramaiah K, Hart JC, Norton L, Dannenberg AJ. Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways. J Biol Chem 2000;275:14838-45.
    • (2000) J Biol Chem , vol.275 , pp. 14838-14845
    • Subbaramaiah, K.1    Hart, J.C.2    Norton, L.3    Dannenberg, A.J.4
  • 21
    • 0037166271 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is overexpressed in HER-2/neupositive breast cancer: Evidence for involvement of AP-1 and PEA3
    • Subbaramaiah K, Norton L, Gerald W, Dannenberg AJ. Cyclooxygenase-2 is overexpressed in HER-2/neupositive breast cancer: evidence for involvement of AP-1 and PEA3. J Biol Chem 2002;277:18649-57.
    • (2002) J Biol Chem , vol.277 , pp. 18649-18657
    • Subbaramaiah, K.1    Norton, L.2    Gerald, W.3    Dannenberg, A.J.4
  • 22
    • 0038079768 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is up-regulated by interleukin-1β in human colorectal cancer cells via multiple signaling pathways
    • Liu W, Reinmuth N, Stoeltzing O, et al. Cyclooxygenase-2 is up-regulated by interleukin-1β in human colorectal cancer cells via multiple signaling pathways. Cancer Res 2003;63:3632-6.
    • (2003) Cancer Res , vol.63 , pp. 3632-3636
    • Liu, W.1    Reinmuth, N.2    Stoeltzing, O.3
  • 23
    • 0037380886 scopus 로고    scopus 로고
    • Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia
    • Holst CR, Nuovo GJ, Esteller M, et al. Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia. Cancer Res 2003;63:1596-601.
    • (2003) Cancer Res , vol.63 , pp. 1596-1601
    • Holst, C.R.1    Nuovo, G.J.2    Esteller, M.3
  • 24
    • 0034697027 scopus 로고    scopus 로고
    • Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3-untranslated region
    • Dixon DA, Kaplan CD, McIntyre TM, Zimmerman GA, Prescott SM. Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3-untranslated region. J Biol Chem 2000;275:11750-7.
    • (2000) J Biol Chem , vol.275 , pp. 11750-11757
    • Dixon, D.A.1    Kaplan, C.D.2    McIntyre, T.M.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 25
    • 0032951716 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes
    • Dean JL, Brook M, Clark AR, Saklatvala J. p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes. J Biol Chem 1999;274:264-9.
    • (1999) J Biol Chem , vol.274 , pp. 264-269
    • Dean, J.L.1    Brook, M.2    Clark, A.R.3    Saklatvala, J.4
  • 26
    • 0035213198 scopus 로고    scopus 로고
    • Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells
    • Dixon DA, Tolley ND, King PH, et al. Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J Clin Invest 2001;108:1657-65.
    • (2001) J Clin Invest , vol.108 , pp. 1657-1665
    • Dixon, D.A.1    Tolley, N.D.2    King, P.H.3
  • 27
    • 0035947709 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
    • Liu CH, Chang SH, Narko K, et al. Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem 2001;276:18563-9.
    • (2001) J Biol Chem , vol.276 , pp. 18563-18569
    • Liu, C.H.1    Chang, S.H.2    Narko, K.3
  • 28
    • 0033119190 scopus 로고    scopus 로고
    • Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells
    • Howe LR, Subbaramaiah K, Chung WJ, Dannenberg AJ, Brown AM. Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells. Cancer Res 1999;59:1572-7.
    • (1999) Cancer Res , vol.59 , pp. 1572-1577
    • Howe, L.R.1    Subbaramaiah, K.2    Chung, W.J.3    Dannenberg, A.J.4    Brown, A.M.5
  • 29
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995;83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 30
    • 0034530889 scopus 로고    scopus 로고
    • The contributions of cyclooxygenase-2 to tumor angiogenesis
    • Gately S. The contributions of cyclooxygenase-2 to tumor angiogenesis. Cancer Metastasis Rev 2000;19:19-27.
    • (2000) Cancer Metastasis Rev , vol.19 , pp. 19-27
    • Gately, S.1
  • 31
    • 0037200088 scopus 로고    scopus 로고
    • Activation of p38α MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization
    • Reunanen N, Li SP, Ahonen M, Foschi M, Han J, Kahari VM. Activation of p38α MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization. J Biol Chem 2002;277:32360-8.
    • (2002) J Biol Chem , vol.277 , pp. 32360-32368
    • Reunanen, N.1    Li, S.P.2    Ahonen, M.3    Foschi, M.4    Han, J.5    Kahari, V.M.6
  • 32
    • 0034697159 scopus 로고    scopus 로고
    • Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38α mitogen-activated protein kinase activity
    • Huang S, New L, Pan Z, Han J, Nemerow GR. Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38α mitogen-activated protein kinase activity. J Biol Chem 2000;275:12266-72.
    • (2000) J Biol Chem , vol.275 , pp. 12266-12272
    • Huang, S.1    New, L.2    Pan, Z.3    Han, J.4    Nemerow, G.R.5
  • 33
    • 0032697491 scopus 로고    scopus 로고
    • Regulation by p38 mitogen-activated protein kinase of adenylate- and uridylate-rich element-mediated urokinase-type plasminogen activator (uPA) messenger RNA stability and uPA-dependent in vitro cell invasion
    • Montero L, Nagamine Y. Regulation by p38 mitogen-activated protein kinase of adenylate- and uridylate-rich element-mediated urokinase-type plasminogen activator (uPA) messenger RNA stability and uPA-dependent in vitro cell invasion. Cancer Res 1999;59:5286-93.
    • (1999) Cancer Res , vol.59 , pp. 5286-5293
    • Montero, L.1    Nagamine, Y.2
  • 34
    • 0032733854 scopus 로고    scopus 로고
    • Matrix-metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: An in situ hybridization study
    • Brummer O, Athar S, Riethdorf L, Loning T, Herbst H. Matrix- metalloproteinases 1, 2, and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study. Virchows Arch 1999;435:566-73.
    • (1999) Virchows Arch , vol.435 , pp. 566-573
    • Brummer, O.1    Athar, S.2    Riethdorf, L.3    Loning, T.4    Herbst, H.5
  • 35
    • 0033993997 scopus 로고    scopus 로고
    • Urokinase plasminogen activator receptor (uPAR): A potential indicator of invasion for in situ breast cancer
    • Guyton DP, Evans DM, Sloan-Stakleff KD. Urokinase plasminogen activator receptor (uPAR): a potential indicator of invasion for in situ breast cancer. Breast J 2000;6:130-6.
    • (2000) Breast J , vol.6 , pp. 130-136
    • Guyton, D.P.1    Evans, D.M.2    Sloan-Stakleff, K.D.3
  • 36
    • 0036674213 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase is required for TGFβ-mediated fibroblastic transdifferentiation and cell migration
    • Bakin AV, Rinehart C, Tomlinson AK, Arteaga CL. p38 mitogen-activated protein kinase is required for TGFβ-mediated fibroblastic transdifferentiation and cell migration. J Cell Sci 2002;115:3193-206.
    • (2002) J Cell Sci , vol.115 , pp. 3193-3206
    • Bakin, A.V.1    Rinehart, C.2    Tomlinson, A.K.3    Arteaga, C.L.4
  • 37
    • 0033607519 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin-independent mechanism
    • Trifan OC, Smith RM, Thompson BD, Hla T. Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin- independent mechanism. J Biol Chem 1999;274:34141-7.
    • (1999) J Biol Chem , vol.274 , pp. 34141-34147
    • Trifan, O.C.1    Smith, R.M.2    Thompson, B.D.3    Hla, T.4
  • 38
    • 0037155787 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression inhibits platelet-derived growth factor-induced mesangial cell proliferation through induction of the tumor suppressor gene p53 and the cyclin-dependent kinase inhibitors p21waf-1/cip-1 and p27kip-1
    • Zahner G, Wolf G, Ayoub M, et al. Cyclooxygenase-2 overexpression inhibits platelet-derived growth factor-induced mesangial cell proliferation through induction of the tumor suppressor gene p53 and the cyclin-dependent kinase inhibitors p21waf-1/cip-1 and p27kip-1. J Biol Chem 2002;277:9763-71.
    • (2002) J Biol Chem , vol.277 , pp. 9763-9771
    • Zahner, G.1    Wolf, G.2    Ayoub, M.3
  • 39
    • 0015237292 scopus 로고
    • Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971;231:232-5.
    • (1971) Nat New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 40
    • 0031787631 scopus 로고    scopus 로고
    • Anti-inflammatory drugs and their mechanism of action
    • Vane JR, Botting RM. Anti-inflammatory drugs and their mechanism of action. Inflamm Res 1998;47 Suppl 2:S78-87.
    • (1998) Inflamm Res , vol.47 , Issue.2 SUPPL.
    • Vane, J.R.1    Botting, R.M.2
  • 41
    • 0035911009 scopus 로고    scopus 로고
    • Efficacy of cyclooxygenase-2-specific inhibitors
    • Cannon GW, Breedveld FC. Efficacy of cyclooxygenase-2-specific inhibitors. Am J Med 2001;110 Suppl 3A:6S-12.
    • (2001) Am J Med , vol.110 , Issue.SUPPL. 3A
    • Cannon, G.W.1    Breedveld, F.C.2


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