메뉴 건너뛰기




Volumn 128, Issue 6, 2007, Pages 1231-1245

Analysis of the Vertebrate Insulator Protein CTCF-Binding Sites in the Human Genome

Author keywords

[No Author keywords available]

Indexed keywords

CCCTC BINDING FACTOR; PROTEIN; UNCLASSIFIED DRUG;

EID: 33947201809     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2006.12.048     Document Type: Article
Times cited : (836)

References (53)
  • 2
    • 0025336820 scopus 로고
    • Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site
    • Baniahmad A., Steiner C., Kohne A.C., and Renkawitz R. Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site. Cell 61 (1990) 505-514
    • (1990) Cell , vol.61 , pp. 505-514
    • Baniahmad, A.1    Steiner, C.2    Kohne, A.C.3    Renkawitz, R.4
  • 3
    • 0034713375 scopus 로고    scopus 로고
    • Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
    • Bell A.C., and Felsenfeld G. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 405 (2000) 482-485
    • (2000) Nature , vol.405 , pp. 482-485
    • Bell, A.C.1    Felsenfeld, G.2
  • 4
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
    • Bell A.C., West A.G., and Felsenfeld G. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98 (1999) 387-396
    • (1999) Cell , vol.98 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 6
    • 0033215443 scopus 로고    scopus 로고
    • Looping versus linking: toward a model for long-distance gene activation
    • Bulger M., and Groudine M. Looping versus linking: toward a model for long-distance gene activation. Genes Dev. 13 (1999) 2465-2477
    • (1999) Genes Dev. , vol.13 , pp. 2465-2477
    • Bulger, M.1    Groudine, M.2
  • 7
    • 0031029141 scopus 로고    scopus 로고
    • Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF
    • Burcin M., Arnold R., Lutz M., Kaiser B., Runge D., Lottspeich F., Filippova G.N., Lobanenkov V.V., and Renkawitz R. Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF. Mol. Cell. Biol. 17 (1997) 1281-1288
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1281-1288
    • Burcin, M.1    Arnold, R.2    Lutz, M.3    Kaiser, B.4    Runge, D.5    Lottspeich, F.6    Filippova, G.N.7    Lobanenkov, V.V.8    Renkawitz, R.9
  • 10
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • Carrel L., and Willard H.F. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434 (2005) 400-404
    • (2005) Nature , vol.434 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 12
  • 13
    • 7444260846 scopus 로고    scopus 로고
    • The ENCODE (ENCyclopedia Of DNA Elements) Project
    • Consortium T.E.P. The ENCODE (ENCyclopedia Of DNA Elements) Project. Science 306 (2004) 636-640
    • (2004) Science , vol.306 , pp. 636-640
    • Consortium, T.E.P.1
  • 14
    • 0041828248 scopus 로고    scopus 로고
    • The many roles of the transcriptional regulator CTCF
    • Dunn K.L., and Davie J.R. The many roles of the transcriptional regulator CTCF. Biochem. Cell Biol. 81 (2003) 161-167
    • (2003) Biochem. Cell Biol. , vol.81 , pp. 161-167
    • Dunn, K.L.1    Davie, J.R.2
  • 15
    • 0347986844 scopus 로고    scopus 로고
    • Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting
    • Fedoriw A.M., Stein P., Svoboda P., Schultz R.M., and Bartolomei M.S. Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science 303 (2004) 238-240
    • (2004) Science , vol.303 , pp. 238-240
    • Fedoriw, A.M.1    Stein, P.2    Svoboda, P.3    Schultz, R.M.4    Bartolomei, M.S.5
  • 17
    • 0029929793 scopus 로고    scopus 로고
    • An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes
    • Filippova G.N., Fagerlie S., Klenova E.M., Myers C., Dehner Y., Goodwin G., Neiman P.E., Collins S.J., and Lobanenkov V.V. An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol. Cell. Biol. 16 (1996) 2802-2813
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2802-2813
    • Filippova, G.N.1    Fagerlie, S.2    Klenova, E.M.3    Myers, C.4    Dehner, Y.5    Goodwin, G.6    Neiman, P.E.7    Collins, S.J.8    Lobanenkov, V.V.9
  • 18
    • 0031977285 scopus 로고    scopus 로고
    • A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers
    • Filippova G.N., Lindblom A., Meincke L.J., Klenova E.M., Neiman P.E., Collins S.J., Doggett N.A., and Lobanenkov V.V. A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers. Genes Chromosomes Cancer 22 (1998) 26-36
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 26-36
    • Filippova, G.N.1    Lindblom, A.2    Meincke, L.J.3    Klenova, E.M.4    Neiman, P.E.5    Collins, S.J.6    Doggett, N.A.7    Lobanenkov, V.V.8
  • 20
    • 11244258156 scopus 로고    scopus 로고
    • Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development
    • Filippova G.N., Cheng M.K., Moore J.M., Truong J.P., Hu Y.J., Nguyen D.K., Tsuchiya K.D., and Disteche C.M. Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development. Dev. Cell 8 (2005) 31-42
    • (2005) Dev. Cell , vol.8 , pp. 31-42
    • Filippova, G.N.1    Cheng, M.K.2    Moore, J.M.3    Truong, J.P.4    Hu, Y.J.5    Nguyen, D.K.6    Tsuchiya, K.D.7    Disteche, C.M.8
  • 21
    • 0035671406 scopus 로고    scopus 로고
    • Chromatin insulators and boundaries: effects on transcription and nuclear organization
    • Gerasimova T.I., and Corces V.G. Chromatin insulators and boundaries: effects on transcription and nuclear organization. Annu. Rev. Genet. 35 (2001) 193-208
    • (2001) Annu. Rev. Genet. , vol.35 , pp. 193-208
    • Gerasimova, T.I.1    Corces, V.G.2
  • 22
    • 0034713275 scopus 로고    scopus 로고
    • CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
    • Hark A.T., Schoenherr C.J., Katz D.J., Ingram R.S., Levorse J.M., and Tilghman S.M. CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature 405 (2000) 486-489
    • (2000) Nature , vol.405 , pp. 486-489
    • Hark, A.T.1    Schoenherr, C.J.2    Katz, D.J.3    Ingram, R.S.4    Levorse, J.M.5    Tilghman, S.M.6
  • 23
    • 6944250434 scopus 로고    scopus 로고
    • Shifting insulator boundaries
    • Jeong S., and Pfeifer K. Shifting insulator boundaries. Nat. Genet. 36 (2004) 1036-1037
    • (2004) Nat. Genet. , vol.36 , pp. 1036-1037
    • Jeong, S.1    Pfeifer, K.2
  • 24
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P.A., and Baylin S.B. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3 (2002) 415-428
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 25
    • 0842265974 scopus 로고    scopus 로고
    • Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors
    • Kadonaga J.T. Regulation of RNA polymerase II transcription by sequence-specific DNA binding factors. Cell 116 (2004) 247-257
    • (2004) Cell , vol.116 , pp. 247-257
    • Kadonaga, J.T.1
  • 26
    • 0034644120 scopus 로고    scopus 로고
    • Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
    • Kanduri C., Pant V., Loukinov D., Pugacheva E., Qi C.F., Wolffe A., Ohlsson R., and Lobanenkov V.V. Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive. Curr. Biol. 10 (2000) 853-856
    • (2000) Curr. Biol. , vol.10 , pp. 853-856
    • Kanduri, C.1    Pant, V.2    Loukinov, D.3    Pugacheva, E.4    Qi, C.F.5    Wolffe, A.6    Ohlsson, R.7    Lobanenkov, V.V.8
  • 28
    • 33646510364 scopus 로고    scopus 로고
    • Genome-wide analysis of protein-DNA interactions
    • Kim T.H., and Ren B. Genome-wide analysis of protein-DNA interactions. Annu. Rev. Genomics Hum. Genet. 7 (2006) 81-102
    • (2006) Annu. Rev. Genomics Hum. Genet. , vol.7 , pp. 81-102
    • Kim, T.H.1    Ren, B.2
  • 31
    • 30044442791 scopus 로고    scopus 로고
    • Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes
    • Kimura K., Wakamatsu A., Suzuki Y., Ota T., Nishikawa T., Yamashita R., Yamamoto J., Sekine M., Tsuritani K., Wakaguri H., et al. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Genome Res. 16 (2006) 55-65
    • (2006) Genome Res. , vol.16 , pp. 55-65
    • Kimura, K.1    Wakamatsu, A.2    Suzuki, Y.3    Ota, T.4    Nishikawa, T.5    Yamashita, R.6    Yamamoto, J.7    Sekine, M.8    Tsuritani, K.9    Wakaguri, H.10
  • 32
    • 0027362621 scopus 로고
    • CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms
    • Klenova E.M., Nicolas R.H., Paterson H.F., Carne A.F., Heath C.M., Goodwin G.H., Neiman P.E., and Lobanenkov V.V. CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms. Mol. Cell. Biol. 13 (1993) 7612-7624
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7612-7624
    • Klenova, E.M.1    Nicolas, R.H.2    Paterson, H.F.3    Carne, A.F.4    Heath, C.M.5    Goodwin, G.H.6    Neiman, P.E.7    Lobanenkov, V.V.8
  • 33
    • 0036781505 scopus 로고    scopus 로고
    • The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer
    • Klenova E.M., Morse III H.C., Ohlsson R., and Lobanenkov V.V. The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer. Semin. Cancer Biol. 12 (2002) 399-414
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 399-414
    • Klenova, E.M.1    Morse III, H.C.2    Ohlsson, R.3    Lobanenkov, V.V.4
  • 34
    • 33746063711 scopus 로고    scopus 로고
    • CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
    • Kurukuti S., Tiwari V.K., Tavoosidana G., Pugacheva E., Murrell A., Zhao Z.H., Lobanenkov V., Reik W., and Ohlsson R. CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc. Natl. Acad. Sci. USA 103 (2006) 10684-10689
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 10684-10689
    • Kurukuti, S.1    Tiwari, V.K.2    Tavoosidana, G.3    Pugacheva, E.4    Murrell, A.5    Zhao, Z.H.6    Lobanenkov, V.7    Reik, W.8    Ohlsson, R.9
  • 35
    • 0037453015 scopus 로고    scopus 로고
    • Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting?
    • Lee J.T. Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting?. Curr. Biol. 13 (2003) R242-R254
    • (2003) Curr. Biol. , vol.13
    • Lee, J.T.1
  • 37
    • 0025675441 scopus 로고
    • A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5′-flanking sequence of the chicken c-myc gene
    • Lobanenkov V.V., Nicolas R.H., Adler V.V., Paterson H., Klenova E.M., Polotskaja A.V., and Goodwin G.H. A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5′-flanking sequence of the chicken c-myc gene. Oncogene 5 (1990) 1743-1753
    • (1990) Oncogene , vol.5 , pp. 1743-1753
    • Lobanenkov, V.V.1    Nicolas, R.H.2    Adler, V.V.3    Paterson, H.4    Klenova, E.M.5    Polotskaja, A.V.6    Goodwin, G.H.7
  • 41
    • 0035451090 scopus 로고    scopus 로고
    • CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease
    • Ohlsson R., Renkawitz R., and Lobanenkov V. CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet. 17 (2001) 520-527
    • (2001) Trends Genet. , vol.17 , pp. 520-527
    • Ohlsson, R.1    Renkawitz, R.2    Lobanenkov, V.3
  • 42
    • 0034923498 scopus 로고    scopus 로고
    • Design and selection of novel Cys2His2 zinc finger proteins
    • Pabo C.O., Peisach E., and Grant R.A. Design and selection of novel Cys2His2 zinc finger proteins. Annu. Rev. Biochem. 70 (2001) 313-340
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 313-340
    • Pabo, C.O.1    Peisach, E.2    Grant, R.A.3
  • 44
    • 0025145277 scopus 로고
    • 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes
    • Rideout III W.M., Coetzee G.A., Olumi A.F., and Jones P.A. 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249 (1990) 1288-1290
    • (1990) Science , vol.249 , pp. 1288-1290
    • Rideout III, W.M.1    Coetzee, G.A.2    Olumi, A.F.3    Jones, P.A.4
  • 46
    • 84860506529 scopus 로고    scopus 로고
    • Mining ChIP-chip data for transcription factor and cofactor binding sites
    • Smith A.D., Sumazin P., Das D., and Zhang M.Q. Mining ChIP-chip data for transcription factor and cofactor binding sites. Bioinformatics 21 Suppl 1 (2005) i403-i412
    • (2005) Bioinformatics , vol.21 , Issue.SUPPL. 1
    • Smith, A.D.1    Sumazin, P.2    Das, D.3    Zhang, M.Q.4
  • 47
    • 13444273342 scopus 로고    scopus 로고
    • Identifying tissue-selective transcription factor binding sites in vertebrate promoters
    • Smith A.D., Sumazin P., and Zhang M.Q. Identifying tissue-selective transcription factor binding sites in vertebrate promoters. Proc. Natl. Acad. Sci. USA 102 (2005) 1560-1565
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 1560-1565
    • Smith, A.D.1    Sumazin, P.2    Zhang, M.Q.3
  • 48
    • 25844496592 scopus 로고    scopus 로고
    • The role of chromatin structure in regulating the expression of clustered genes
    • Sproul D., Gilbert N., and Bickmore W.A. The role of chromatin structure in regulating the expression of clustered genes. Nat. Rev. Genet. 6 (2005) 775-781
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 775-781
    • Sproul, D.1    Gilbert, N.2    Bickmore, W.A.3
  • 49
    • 0022178109 scopus 로고
    • The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains
    • Udvardy A., Maine E., and Schedl P. The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains. J. Mol. Biol. 185 (1985) 341-358
    • (1985) J. Mol. Biol. , vol.185 , pp. 341-358
    • Udvardy, A.1    Maine, E.2    Schedl, P.3
  • 50
    • 0031468080 scopus 로고    scopus 로고
    • The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation
    • Vostrov A.A., and Quitschke W.W. The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation. J. Biol. Chem. 272 (1997) 33353-33359
    • (1997) J. Biol. Chem. , vol.272 , pp. 33353-33359
    • Vostrov, A.A.1    Quitschke, W.W.2
  • 53
    • 0842310349 scopus 로고    scopus 로고
    • CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species
    • Yusufzai T.M., Tagami H., Nakatani Y., and Felsenfeld G. CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species. Mol. Cell 13 (2004) 291-298
    • (2004) Mol. Cell , vol.13 , pp. 291-298
    • Yusufzai, T.M.1    Tagami, H.2    Nakatani, Y.3    Felsenfeld, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.