TGF-β1 induces COX-2 expression and PGE2 synthesis through MAPK and PI3K pathways in human mesangial cells

Kidney International

Volumn 70, Issue 5, 2006, Pages 901-909

  Rodriguez Barbero A ^a   Dorado, F ^a   Velasco, S ^a   Pandiella, A ^b   Banas, B ^c   Lopez Novoa J M ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b Salamanca Spain   (Spain)

^c UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

Cyclooxygenase; Mesangial cells; Mitogen activated protein kinase; Phosphatidylinositol 3 kinase; Prostaglandin E 2; Transforming growth factor 1

Indexed keywords

CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; TRANSFORMING GROWTH FACTOR BETA1; COLLAGEN TYPE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL CULTURE; CELL IMMORTALIZATION; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME REGULATION; GLOMERULOPATHY; HUMAN; HUMAN CELL; HUMAN TISSUE; MESANGIUM CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL PROLIFERATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE I; CYCLOOXYGENASE 2; DINOPROSTONE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MESANGIAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33747854099     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5001626     Document Type: Article

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