메뉴 건너뛰기




Volumn 34, Issue 11, 2014, Pages 2062-2074

USP28 is recruited to sites of DNA damage by the tandem BRCT domains of 53BP1 but plays a minor role in double-strand break metabolism

Author keywords

[No Author keywords available]

Indexed keywords

DEUBIQUITINASE; DNA BINDING PROTEIN; P53 BINDING PROTEIN; SMALL INTERFERING RNA; UBIQUITIN SPECIFIC PROTEASE 28; UNCLASSIFIED DRUG;

EID: 84899880562     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00197-14     Document Type: Article
Times cited : (47)

References (71)
  • 1
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson SP, Bartek J. 2009. The DNA-damage response in human biology and disease. Nature 461:1071-1078. http://dx.doi.org/10.1038/nature 08467.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 2
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: making it safe to play with knives
    • Ciccia A, Elledge SJ. 2010. The DNA damage response: making it safe to play with knives. Mol. Cell 40:179-204. http://dx.doi.org/10.1016/j.molcel.2010.09.019.
    • (2010) Mol. Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 3
    • 78951474460 scopus 로고    scopus 로고
    • The MRE11 complex: starting from the ends
    • Stracker TH, Petrini JH. 2011. The MRE11 complex: starting from the ends. Nat. Rev. Mol. Cell Biol. 12:90-103. http://dx.doi.org/10.1038/nrm3047.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 90-103
    • Stracker, T.H.1    Petrini, J.H.2
  • 4
    • 84876174441 scopus 로고    scopus 로고
    • The ATM signaling network in development and disease
    • Stracker TH, Roig I, Knobel PA, Marjanovic M. 2013. The ATM signaling network in development and disease. Front Genet. 4:37. http://dx.doi.org/10.3389/fgene.2013.00037.
    • (2013) Front Genet , vol.4 , pp. 37
    • Stracker, T.H.1    Roig, I.2    Knobel, P.A.3    Marjanovic, M.4
  • 5
    • 84876886904 scopus 로고    scopus 로고
    • Regulation of DNA damage responses by ubiquitin and SUMO
    • Jackson SP, Durocher D. 2013. Regulation of DNA damage responses by ubiquitin and SUMO. Mol. Cell 49:795-807. http://dx.doi.org/10.1016/j.molcel.2013.01.017.
    • (2013) Mol. Cell , vol.49 , pp. 795-807
    • Jackson, S.P.1    Durocher, D.2
  • 6
    • 79251473377 scopus 로고    scopus 로고
    • Will the ubiquitin system furnish as many drug targets as protein kinases?
    • Cohen P, Tcherpakov M. 2010. Will the ubiquitin system furnish as many drug targets as protein kinases? Cell 143:686-693. http://dx.doi.org/10.1016/j.cell.2010.11.016.
    • (2010) Cell , vol.143 , pp. 686-693
    • Cohen, P.1    Tcherpakov, M.2
  • 7
    • 0035942190 scopus 로고    scopus 로고
    • Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
    • Ruffner H, Joazeiro CA, Hemmati D, Hunter T, Verma IM. 2001. Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc. Natl. Acad. Sci. U. S. A. 98:5134-5139. http://dx.doi.org/10.1073/pnas.081068398.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 5134-5139
    • Ruffner, H.1    Joazeiro, C.A.2    Hemmati, D.3    Hunter, T.4    Verma, I.M.5
  • 8
    • 0038237514 scopus 로고    scopus 로고
    • Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein
    • Xia Y, Pao GM, Chen HW, Verma IM, Hunter T. 2003. Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein. J. Biol. Chem. 278:5255-5263. http://dx.doi.org/10.1074/jbc. M204591200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5255-5263
    • Xia, Y.1    Pao, G.M.2    Chen, H.W.3    Verma, I.M.4    Hunter, T.5
  • 9
    • 59449094470 scopus 로고    scopus 로고
    • An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks
    • Zgheib O, Pataky K, Brugger J, Halazonetis TD. 2009. An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks. Mol. Cell. Biol. 29:1050-1058. http://dx.doi.org/10.1128/MCB.01011-08.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 1050-1058
    • Zgheib, O.1    Pataky, K.2    Brugger, J.3    Halazonetis, T.D.4
  • 11
    • 33845666681 scopus 로고    scopus 로고
    • Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
    • Botuyan MV, Lee J, Ward IM, Kim JE, Thompson JR, Chen J, Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127:1361-1373. http://dx.doi.org/10.1016/j.cell.2006.10.043.
    • Cell , vol.127 , pp. 1361-1373
    • Botuyan, M.V.1    Lee, J.2    Ward, I.M.3    Kim, J.E.4    Thompson, J.R.5    Chen, J.6    Mer, G.7
  • 13
    • 57049132043 scopus 로고    scopus 로고
    • 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
    • Dimitrova N, Chen YC, Spector DL, de Lange T. 2008. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 456:524-528. http://dx.doi.org/10.1038/nature07433.
    • (2008) Nature , vol.456 , pp. 524-528
    • Dimitrova, N.1    Chen, Y.C.2    Spector, D.L.3    de Lange, T.4
  • 14
    • 2442707746 scopus 로고    scopus 로고
    • 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
    • Manis JP, Morales JC, Xia Z, Kutok JL, Alt FW, Carpenter PB. 2004. 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat. Immunol. 5:481-487. http://dx.doi.org/10.1038/ni1067.
    • (2004) Nat. Immunol. , vol.5 , pp. 481-487
    • Manis, J.P.1    Morales, J.C.2    Xia, Z.3    Kutok, J.L.4    Alt, F.W.5    Carpenter, P.B.6
  • 17
    • 0037378527 scopus 로고    scopus 로고
    • p53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice
    • Ward IM, Minn K, van Deursen J, Chen J. 2003. p53 binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice. Mol. Cell. Biol. 23:2556-2563. http://dx.doi.org/10.1128/MCB.23.7.2556-2563.2003.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2556-2563
    • Ward, I.M.1    Minn, K.2    van Deursen, J.3    Chen, J.4
  • 22
    • 84883458147 scopus 로고    scopus 로고
    • Deubiquitylating enzymes and DNA damage response pathways
    • Jacq X, Kemp M, Martin NM, Jackson SP. 2013. Deubiquitylating enzymes and DNA damage response pathways. Cell Biochem. Biophys. 67:25-43. http://dx.doi.org/10.1007/s12013-013-9635-3.
    • (2013) Cell Biochem. Biophys. , vol.67 , pp. 25-43
    • Jacq, X.1    Kemp, M.2    Martin, N.M.3    Jackson, S.P.4
  • 23
    • 33746766974 scopus 로고    scopus 로고
    • A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response
    • Zhang D, Zaugg K, Mak TW, Elledge SJ. 2006. A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell 126:529-542. http://dx.doi.org/10.1016/j.cell.2006.06.039.
    • (2006) Cell , vol.126 , pp. 529-542
    • Zhang, D.1    Zaugg, K.2    Mak, T.W.3    Elledge, S.J.4
  • 24
    • 47549098471 scopus 로고    scopus 로고
    • The Cdc14B-Cdh1-Plk1 axis controls the G2 DNAdamage- response checkpoint
    • Bassermann F, Frescas D, Guardavaccaro D, Busino L, Peschiaroli A, Pagano M. 2008. The Cdc14B-Cdh1-Plk1 axis controls the G2 DNAdamage- response checkpoint. Cell 134:256-267. http://dx.doi.org/10.1016/j.cell.2008.05.043.
    • (2008) Cell , vol.134 , pp. 256-267
    • Bassermann, F.1    Frescas, D.2    Guardavaccaro, D.3    Busino, L.4    Peschiaroli, A.5    Pagano, M.6
  • 27
    • 84857391512 scopus 로고    scopus 로고
    • Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance
    • Campaner S, Amati B. 2012. Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance. Cell Div. 7:6. http://dx.doi.org/10.1186/1747-1028-7-6.
    • (2012) Cell Div. , vol.7 , pp. 6
    • Campaner, S.1    Amati, B.2
  • 28
    • 35848942129 scopus 로고    scopus 로고
    • Fbw7 and Usp28 regulate myc protein stability in response toDNAdamage
    • Popov N, Herold S, Llamazares M, Schulein C, Eilers M. 2007. Fbw7 and Usp28 regulate myc protein stability in response toDNAdamage. Cell Cycle 6:2327-2331. http://dx.doi.org/10.4161/cc.6.19.4804.
    • (2007) Cell Cycle , vol.6 , pp. 2327-2331
    • Popov, N.1    Herold, S.2    Llamazares, M.3    Schulein, C.4    Eilers, M.5
  • 29
    • 2942650133 scopus 로고    scopus 로고
    • The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
    • Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE. 2004. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc. Natl. Acad. Sci. U. S. A. 101:9085-9090. http://dx.doi.org/10.1073/pnas.0402770101.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 9085-9090
    • Welcker, M.1    Orian, A.2    Jin, J.3    Grim, J.E.4    Harper, J.W.5    Eisenman, R.N.6    Clurman, B.E.7
  • 31
    • 72449175818 scopus 로고    scopus 로고
    • MammalianSUMOE3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
    • Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP. MammalianSUMOE3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature 462:935-939. http://dx.doi.org/10.1038/nature08657.
    • Nature , vol.462 , pp. 935-939
    • Galanty, Y.1    Belotserkovskaya, R.2    Coates, J.3    Polo, S.4    Miller, K.M.5    Jackson, S.P.6
  • 32
    • 0027190834 scopus 로고
    • A new method for introducing double-strand breaks into cellular DNA
    • Limoli CL, Ward JF. 1993. A new method for introducing double-strand breaks into cellular DNA. Radiat Res. 134:160-169.
    • (1993) Radiat Res. , vol.134 , pp. 160-169
    • Limoli, C.L.1    Ward, J.F.2
  • 33
    • 78149284014 scopus 로고    scopus 로고
    • TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint
    • Cescutti R, Negrini S, Kohzaki M, Halazonetis TD. 2010. TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint. EMBO J. 39: 3723-3732. http://dx.doi.org/10.1038/emboj.2010.238.
    • (2010) EMBO J. , vol.39 , pp. 3723-3732
    • Cescutti, R.1    Negrini, S.2    Kohzaki, M.3    Halazonetis, T.D.4
  • 35
    • 0030874643 scopus 로고    scopus 로고
    • The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: a severe combined immune deficiency (SCID) murine model
    • Lista F, Bertness V, Guidos CJ, Danska JS, Kirsch IR. 1997. The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: a severe combined immune deficiency (SCID) murine model. Cancer Res. 57:4408-4413.
    • (1997) Cancer Res. , vol.57 , pp. 4408-4413
    • Lista, F.1    Bertness, V.2    Guidos, C.J.3    Danska, J.S.4    Kirsch, I.R.5
  • 37
    • 0038143321 scopus 로고    scopus 로고
    • Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
    • Ward IM, Minn K, Jorda KG, Chen J. 2003. Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J. Biol. Chem. 278:19579-19582. http://dx.doi.org/10.1074/jbc. C300117200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 19579-19582
    • Ward, I.M.1    Minn, K.2    Jorda, K.G.3    Chen, J.4
  • 38
    • 79952235291 scopus 로고    scopus 로고
    • Dynamics of DNA damage response proteins atDNAbreaks: a focus on protein modifications
    • Polo SE, Jackson SP. 2011. Dynamics of DNA damage response proteins atDNAbreaks: a focus on protein modifications. Genes Dev. 25:409-433. http://dx.doi.org/10.1101/gad.2021311.
    • (2011) Genes Dev. , vol.25 , pp. 409-433
    • Polo, S.E.1    Jackson, S.P.2
  • 39
    • 77949708459 scopus 로고    scopus 로고
    • Regulation of chromatin architecture by the PWWP domain- containing DNA damage-responsive factor EXPAND1/MUM1
    • Huen MS, Huang J, Leung JW, Sy SM, Leung KM, Ching YP, Tsao SW, Chen J. 2010. Regulation of chromatin architecture by the PWWP domain- containing DNA damage-responsive factor EXPAND1/MUM1. Mol. Cell 37:854-864. http://dx.doi.org/10.1016/j.molcel.2009.12.040.
    • (2010) Mol. Cell , vol.37 , pp. 854-864
    • Huen, M.S.1    Huang, J.2    Leung, J.W.3    Sy, S.M.4    Leung, K.M.5    Ching, Y.P.6    Tsao, S.W.7    Chen, J.8
  • 41
    • 0025954329 scopus 로고
    • Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia
    • Kobayashi Y, Tycko B, Soreng AL, Sklar J. 1991. Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia. J. Immunol. 147:3201-3209.
    • (1991) J. Immunol. , vol.147 , pp. 3201-3209
    • Kobayashi, Y.1    Tycko, B.2    Soreng, A.L.3    Sklar, J.4
  • 43
    • 46149124528 scopus 로고    scopus 로고
    • Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage
    • Stracker TH, Couto SS, Cordon-Cardo C, Matos T, Petrini JH. 2008. Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage. Mol. Cell 31:21-32. http://dx.doi.org/10.1016/j.molcel.2008.04.028.
    • (2008) Mol. Cell , vol.31 , pp. 21-32
    • Stracker, T.H.1    Couto, S.S.2    Cordon-Cardo, C.3    Matos, T.4    Petrini, J.H.5
  • 45
    • 84865364870 scopus 로고    scopus 로고
    • Playing the end game: DNA double-strand break repair pathway choice
    • Chapman JR, Taylor MR, Boulton SJ. 2012. Playing the end game: DNA double-strand break repair pathway choice. Mol. Cell 47:497-510. http://dx.doi.org/10.1016/j.molcel.2012.07.029.
    • (2012) Mol. Cell , vol.47 , pp. 497-510
    • Chapman, J.R.1    Taylor, M.R.2    Boulton, S.J.3
  • 51
    • 84873488846 scopus 로고    scopus 로고
    • 53BP1 regulates DSB repair using Rif1 to control 5= end resection
    • Zimmermann M, Lottersberger F, Buonomo SB, Sfeir A, de Lange T.53BP1 regulates DSB repair using Rif1 to control 5= end resection. Science 339:700-704. http://dx.doi.org/10.1126/science.1231573.
    • Science; , vol.339 , pp. 700-704
    • Zimmermann, M.1    Lottersberger, F.2    Buonomo, S.B.3    Sfeir, A.4    de Lange, T.5
  • 54
    • 0036500691 scopus 로고    scopus 로고
    • Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure
    • Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP. 2002. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev. 16:583-593. http://dx.doi.org/10.1101/gad.959202.
    • (2002) Genes Dev. , vol.16 , pp. 583-593
    • Joo, W.S.1    Jeffrey, P.D.2    Cantor, S.B.3    Finnin, M.S.4    Livingston, D.M.5    Pavletich, N.P.6
  • 57
    • 0142147272 scopus 로고    scopus 로고
    • The BRCT domain is a phospho-protein binding domain
    • Yu X, Chini CC, He M, Mer G, Chen J. 2003. The BRCT domain is a phospho-protein binding domain. Science 302:639-642. http://dx.doi.org/10.1126/science.1088753.
    • (2003) Science; , vol.302 , pp. 639-642
    • Yu, X.1    Chini, C.C.2    He, M.3    Mer, G.4    Chen, J.5
  • 58
    • 0142240342 scopus 로고    scopus 로고
    • BRCT repeats as phosphopeptide-binding modules involved in protein targeting
    • Manke IA, Lowery DM, Nguyen A, Yaffe MB. 2003. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 302:636-639. http://dx.doi.org/10.1126/science.1088877.
    • (2003) Science; , vol.302 , pp. 636-639
    • Manke, I.A.1    Lowery, D.M.2    Nguyen, A.3    Yaffe, M.B.4
  • 59
    • 84861189396 scopus 로고    scopus 로고
    • Tumor suppressor functions of FBW7 in cancer development and progression
    • Wang Z, Inuzuka H, Zhong J, Wan L, Fukushima H, Sarkar FH, Wei W. 2012. Tumor suppressor functions of FBW7 in cancer development and progression. FEBS Lett. 586:1409-1418. http://dx.doi.org/10.1016/j.febslet.2012.03.017.
    • (2012) FEBS Lett.; , vol.586 , pp. 1409-1418
    • Wang, Z.1    Inuzuka, H.2    Zhong, J.3    Wan, L.4    Fukushima, H.5    Sarkar, F.H.6    Wei, W.7
  • 60
    • 38549086019 scopus 로고    scopus 로고
    • FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
    • Welcker M, Clurman BE. 2008. FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat. Rev. Cancer. 8:83-93. http://dx.doi.org/10.1038/nrc2290.
    • (2008) Nat. Rev. Cancer.; , vol.8 , pp. 83-93
    • Welcker, M.1    Clurman, B.E.2
  • 63
    • 84883590611 scopus 로고    scopus 로고
    • Pirh2: an E3 ligase with central roles in the regulation of cell cycle, DNA damage response, and differentiation
    • Halaby MJ, Hakem R, Hakem A. 2013. Pirh2: an E3 ligase with central roles in the regulation of cell cycle, DNA damage response, and differentiation. Cell Cycle 12:2733-2737. http://dx.doi.org/10.4161/cc.25785.
    • (2013) Cell Cycle , vol.12 , pp. 2733-2737
    • Halaby, M.J.1    Hakem, R.2    Hakem, A.3
  • 65
    • 84885868036 scopus 로고    scopus 로고
    • The deubiquitinase USP28 stabilizes LSD1 and confers stemcell- like traits to breast cancer cells
    • Wu Y, Wang Y, Yang XH, Kang T, Zhao Y, Wang C, Evers BM, Zhou BP. 2013. The deubiquitinase USP28 stabilizes LSD1 and confers stemcell- like traits to breast cancer cells. Cell Rep. 5:224-236. http://dx.doi.org/10.1016/j.celrep.2013.08.030.
    • (2013) Cell Rep.; , vol.5 , pp. 224-236
    • Wu, Y.1    Wang, Y.2    Yang, X.H.3    Kang, T.4    Zhao, Y.5    Wang, C.6    Evers, B.M.7    Zhou, B.P.8
  • 70
    • 84856604061 scopus 로고    scopus 로고
    • GSK-3 regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1
    • Flugel D, Gorlach A, Kietzmann T. 2012. GSK-3 regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1. Blood 119:1292-1301. http://dx.doi.org/10.1182/blood-2011-08-375014.
    • (2012) Blood; , vol.119 , pp. 1292-1301
    • Flugel, D.1    Gorlach, A.2    Kietzmann, T.3
  • 71
    • 33745186920 scopus 로고    scopus 로고
    • Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells
    • Biton S, Dar I, Mittelman L, Pereg Y, Barzilai A, Shiloh Y. 2006. Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells. J. Biol. Chem. 281:17482-17491. http://dx.doi.org/10.1074/jbc. M601895200.
    • (2006) J. Biol. Chem.; , vol.281 , pp. 17482-17491
    • Biton, S.1    Dar, I.2    Mittelman, L.3    Pereg, Y.4    Barzilai, A.5    Shiloh, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.