-
1
-
-
0000297776
-
Familial auricular fibrillation
-
Wolff L. Familial auricular fibrillation. N Engl J Med. 1943;229:396-398.
-
(1943)
N Engl J Med
, vol.229
, pp. 396-398
-
-
Wolff, L.1
-
3
-
-
0038037760
-
Familial atrial fibrillation is a genetically heterogeneous disorder
-
Darbar D, Herron KJ, Ballew JD, Jahangir A, Gersh BJ, Shen WK, Hammill SC, Packer DL, Olson TM. Familial atrial fibrillation is a genetically heterogeneous disorder. J Am Coll Cardiol. 2003;41:2185-2192.
-
(2003)
J Am Coll Cardiol
, vol.41
, pp. 2185-2192
-
-
Darbar, D.1
Herron, K.J.2
Ballew, J.D.3
Jahangir, A.4
Gersh, B.J.5
Shen, W.K.6
Hammill, S.C.7
Packer, D.L.8
Olson, T.M.9
-
4
-
-
2942537772
-
Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring
-
Fox CS, Parise H, D'Agostino RB Sr, Lloyd-Jones DM, Vasan RS, Wang TJ, Levy D, Wolf PA, Benjamin EJ. Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring. JAMA. 2004;291:2851-2855.
-
(2004)
JAMA
, vol.291
, pp. 2851-2855
-
-
Fox, C.S.1
Parise, H.2
D'Agostino Sr., R.B.3
Lloyd-Jones, D.M.4
Vasan, R.S.5
Wang, T.J.6
Levy, D.7
Wolf, P.A.8
Benjamin, E.J.9
-
5
-
-
33644893375
-
Familial aggregation of atrial fibrillation in Iceland
-
Arnar DO, Thorvaldsson S, Manolio TA, Thorgeirsson G, Kristjansson K, Hakonarson H, Stefansson K. Familial aggregation of atrial fibrillation in Iceland. Eur Heart J. 2006;27:708-712.
-
(2006)
Eur Heart J
, vol.27
, pp. 708-712
-
-
Arnar, D.O.1
Thorvaldsson, S.2
Manolio, T.A.3
Thorgeirsson, G.4
Kristjansson, K.5
Hakonarson, H.6
Stefansson, K.7
-
6
-
-
78649455031
-
Association between familial atrial fibrillation and risk of new-onset atrial fibrillation
-
Lubitz SA, Yin X, Fontes JD, Magnani JW, Rienstra M, Pai M, Villalon ML, Vasan RS, Pencina MJ, Levy D, Larson MG, Ellinor PT, Benjamin EJ. Association between familial atrial fibrillation and risk of new-onset atrial fibrillation. JAMA. 2010;304:2263-2269.
-
(2010)
JAMA
, vol.304
, pp. 2263-2269
-
-
Lubitz, S.A.1
Yin, X.2
Fontes, J.D.3
Magnani, J.W.4
Rienstra, M.5
Pai, M.6
Villalon, M.L.7
Vasan, R.S.8
Pencina, M.J.9
Levy, D.10
Larson, M.G.11
Ellinor, P.T.12
Benjamin, E.J.13
-
7
-
-
0031004845
-
Identification of a genetic locus for familial atrial fibrillation
-
Brugada R, Tapscott T, Czernuszewicz GZ, Marian AJ, Iglesias A, Mont L, Brugada J, Girona J, Domingo A, Bachinski LL, Roberts R. Identification of a genetic locus for familial atrial fibrillation. N Engl J Med. 1997;336:905-911.
-
(1997)
N Engl J Med
, vol.336
, pp. 905-911
-
-
Brugada, R.1
Tapscott, T.2
Czernuszewicz, G.Z.3
Marian, A.J.4
Iglesias, A.5
Mont, L.6
Brugada, J.7
Girona, J.8
Domingo, A.9
Bachinski, L.L.10
Roberts, R.11
-
8
-
-
0037428218
-
KCNQ1 gain-of-function mutation in familial atrial fibrillation
-
Chen YH, Xu SJ, Bendahhou S, et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation. Science. 2003;299:251-254.
-
(2003)
Science
, vol.299
, pp. 251-254
-
-
Chen, Y.H.1
Xu, S.J.2
Bendahhou, S.3
-
9
-
-
84891500443
-
A novel KCNQ1 missense mutation identified in a patient with juvenile-onset atrial fibrillation causes constitutively open IKs channels
-
Hasegawa K, Ohno S, Ashihara T, Itoh H, Ding W-G, Toyoda F, Makiyama T, Aoki H, Nakamura Y, Delisle BP, Matsuura H, Horie M. A novel KCNQ1 missense mutation identified in a patient with juvenile-onset atrial fibrillation causes constitutively open IKs channels. Heart Rhythm. 2014;11(1):67-75.
-
(2014)
Heart Rhythm
, vol.11
, Issue.1
, pp. 67-75
-
-
Hasegawa, K.1
Ohno, S.2
Ashihara, T.3
Itoh, H.4
Ding, W.-G.5
Toyoda, F.6
Makiyama, T.7
Aoki, H.8
Nakamura, Y.9
Delisle, B.P.10
Matsuura, H.11
Horie, M.12
-
10
-
-
84896739914
-
A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation
-
Ki CS, Jung CL, Kim HJ, Baek KH, Park SJ, On YK, Kim KS, Noh SJ, Youm JB, Kim JS, Cho H. A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation. Pflugers Arch. 2014;466:529-540.
-
(2014)
Pflugers Arch
, vol.466
, pp. 529-540
-
-
Ki, C.S.1
Jung, C.L.2
Kim, H.J.3
Baek, K.H.4
Park, S.J.5
On, Y.K.6
Kim, K.S.7
Noh, S.J.8
Youm, J.B.9
Kim, J.S.10
Cho, H.11
-
11
-
-
84876933197
-
A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation
-
Bartos DC, Anderson JB, Bastiaenen R, Johnson JN, Gollob MH, Tester DJ, Burgess DE, Homfray T, Behr ER, Ackerman MJ, Guicheney P, Delisle BP. A KCNQ1 mutation causes a high penetrance for familial atrial fibrillation. J Cardiovasc Electrophysiol. 2013;24:562-569.
-
(2013)
J Cardiovasc Electrophysiol
, vol.24
, pp. 562-569
-
-
Bartos, D.C.1
Anderson, J.B.2
Bastiaenen, R.3
Johnson, J.N.4
Gollob, M.H.5
Tester, D.J.6
Bild, D.E.7
Homfray, T.8
Behr, E.R.9
Ackerman, M.J.10
Guicheney, P.11
Delisle, B.P.12
-
12
-
-
78650665141
-
R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation
-
Bartos DC, Duchatelet S, Burgess DE, Klug D, Denjoy I, Peat R, Lupoglazoff JM, Fressart V, Berthet M, Ackerman MJ, January CT, Guicheney P, Delisle BP. R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation. Heart Rhythm. 2011;8:48-55.
-
(2011)
Heart Rhythm
, vol.8
, pp. 48-55
-
-
Bartos, D.C.1
Duchatelet, S.2
Bild, D.E.3
Klug, D.4
Denjoy, I.5
Peat, R.6
Lupoglazoff, J.M.7
Fressart, V.8
Berthet, M.9
Ackerman, M.J.10
January, C.T.11
Guicheney, P.12
Delisle, B.P.13
-
13
-
-
67650738504
-
Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation
-
Das S, Makino S, Melman YF, Shea MA, Goyal SB, Rosenzweig A, Macrae CA, Ellinor PT. Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation. Heart Rhythm. 2009;6:1146-1153.
-
(2009)
Heart Rhythm
, vol.6
, pp. 1146-1153
-
-
Das, S.1
Makino, S.2
Melman, Y.F.3
Shea, M.A.4
Goyal, S.B.5
Rosenzweig, A.6
Macrae, C.A.7
Ellinor, P.T.8
-
14
-
-
36549055058
-
KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval
-
Lundby A, Ravn LS, Svendsen JH, Olesen SP, Schmitt N. KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval. Heart Rhythm. 2007;4:1532-1541.
-
(2007)
Heart Rhythm
, vol.4
, pp. 1532-1541
-
-
Lundby, A.1
Ravn, L.S.2
Svendsen, J.H.3
Olesen, S.P.4
Schmitt, N.5
-
15
-
-
33846517015
-
KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation
-
Olson TM, Alekseev AE, Moreau C, Liu XK, Zingman LV, Miki T, Seino S, Asirvatham SJ, Jahangir A, Terzic A. KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation. Nat Clin Pract Cardiovasc Med. 2007;4:110-116.
-
(2007)
Nat Clin Pract Cardiovasc Med
, vol.4
, pp. 110-116
-
-
Olson, T.M.1
Alekseev, A.E.2
Moreau, C.3
Liu, X.K.4
Zingman, L.V.5
Miki, T.6
Seino, S.7
Asirvatham, S.J.8
Jahangir, A.9
Terzic, A.10
-
16
-
-
79960637374
-
GATA4 loss-of-function mutations in familial atrial fibrillation
-
Yang YQ, Wang MY, Zhang XL, Tan HW, Shi HF, Jiang WF, Wang XH, Fang WY, Liu X. GATA4 loss-of-function mutations in familial atrial fibrillation. Clin Chim Acta. 2011;412:1825-1830.
-
(2011)
Clin Chim Acta
, vol.412
, pp. 1825-1830
-
-
Yang, Y.Q.1
Wang, M.Y.2
Zhang, X.L.3
Tan, H.W.4
Shi, H.F.5
Jiang, W.F.6
Wang, X.H.7
Fang, W.Y.8
Liu, X.9
-
17
-
-
80053514161
-
Novel GATA4 mutations in lone atrial fibrillation
-
Jiang JQ, Shen FF, Fang WY, Liu X, Yang YQ. Novel GATA4 mutations in lone atrial fibrillation. Int J Mol Med. 2011;28:1025-1032.
-
(2011)
Int J Mol Med
, vol.28
, pp. 1025-1032
-
-
Jiang, J.Q.1
Shen, F.F.2
Fang, W.Y.3
Liu, X.4
Yang, Y.Q.5
-
18
-
-
84868654770
-
Mutation spectrum of the GATA4 gene in patients with idiopathic atrial fibrillation
-
Wang J, Sun YM, Yang YQ. Mutation spectrum of the GATA4 gene in patients with idiopathic atrial fibrillation. Mol Biol Rep. 2012;39:8127-8135.
-
(2012)
Mol Biol Rep
, vol.39
, pp. 8127-8135
-
-
Wang, J.1
Sun, Y.M.2
Yang, Y.Q.3
-
19
-
-
77954385004
-
Mutations in the cardiac transcription factor GATA4 in patients with lone atrial fibrillation
-
Posch MG, Boldt LH, Polotzki M, Richter S, Rolf S, Perrot A, Dietz R, Ozcelik C, Haverkamp W. Mutations in the cardiac transcription factor GATA4 in patients with lone atrial fibrillation. Eur J Med Genet. 2010;53:201-203.
-
(2010)
Eur J Med Genet
, vol.53
, pp. 201-203
-
-
Posch, M.G.1
Boldt, L.H.2
Polotzki, M.3
Richter, S.4
Rolf, S.5
Perrot, A.6
Dietz, R.7
Ozcelik, C.8
Haverkamp, W.9
-
20
-
-
84872337181
-
Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation
-
Gu JY, Xu JH, Yu H, Yang YQ. Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation. Clinics (Sao Paulo). 2012;67:1393-1399.
-
(2012)
Clinics (Sao Paulo
, vol.67
, pp. 1393-1399
-
-
Gu, J.Y.1
Xu, J.H.2
Yu, H.3
Yang, Y.Q.4
-
21
-
-
84873203339
-
A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation
-
Wang XH, Huang CX, Wang Q, Li RG, Xu YJ, Liu X, Fang WY, Yang YQ. A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation. Int J Mol Med. 2013;31:43-50.
-
(2013)
Int J Mol Med
, vol.31
, pp. 43-50
-
-
Wang, X.H.1
Huang, C.X.2
Wang, Q.3
Li, R.G.4
Xu, Y.J.5
Liu, X.6
Fang, W.Y.7
Yang, Y.Q.8
-
22
-
-
84861093233
-
Mutational spectrum of the GATA5 gene associated with familial atrial fibrillation
-
Yang YQ, Wang J, Wang XH, Wang Q, Tan HW, Zhang M, Shen FF, Jiang JQ, Fang WY, Liu X. Mutational spectrum of the GATA5 gene associated with familial atrial fibrillation. Int J Cardiol. 2012;157:305-307.
-
(2012)
Int J Cardiol
, vol.157
, pp. 305-307
-
-
Yang, Y.Q.1
Wang, J.2
Wang, X.H.3
Wang, Q.4
Tan, H.W.5
Zhang, M.6
Shen, F.F.7
Jiang, J.Q.8
Fang, W.Y.9
Liu, X.10
-
23
-
-
84866361756
-
GATA6 loss-of-function mutation in atrial fibrillation
-
Yang YQ, Li L, Wang J, Zhang XL, Li RG, Xu YJ, Tan HW, Wang XH, Jiang JQ, Fang WY, Liu X. GATA6 loss-of-function mutation in atrial fibrillation. Eur J Med Genet. 2012;55:520-526.
-
(2012)
Eur J Med Genet
, vol.55
, pp. 520-526
-
-
Yang, Y.Q.1
Li, L.2
Wang, J.3
Zhang, X.L.4
Li, R.G.5
Xu, Y.J.6
Tan, H.W.7
Wang, X.H.8
Jiang, J.Q.9
Fang, W.Y.10
Liu, X.11
-
24
-
-
84862777261
-
Prevalence and spectrum of GATA6 mutations associated with familial atrial fibrillation
-
Yang YQ, Wang XH, Tan HW, Jiang WF, Fang WY, Liu X. Prevalence and spectrum of GATA6 mutations associated with familial atrial fibrillation. Int J Cardiol. 2012;155:494-496.
-
(2012)
Int J Cardiol
, vol.155
, pp. 494-496
-
-
Yang, Y.Q.1
Wang, X.H.2
Tan, H.W.3
Jiang, W.F.4
Fang, W.Y.5
Liu, X.6
-
25
-
-
84866520748
-
Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation
-
Li J, Liu WD, Yang ZL, Yang YQ. Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation. Int J Mol Med. 2012;30: 783-790.
-
(2012)
Int J Mol Med
, vol.30
, pp. 783-790
-
-
Li, J.1
Liu, W.D.2
Yang, Z.L.3
Yang, Y.Q.4
-
26
-
-
33745246602
-
Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation
-
Gollob MH, Jones DL, Krahn AD, et al. Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation. N Engl J Med. 2006;354:2677-2688.
-
(2006)
N Engl J Med
, vol.354
, pp. 2677-2688
-
-
Gollob, M.H.1
Jones, D.L.2
Krahn, A.D.3
-
27
-
-
84871435434
-
Rare variants in GJA5 are associated with early-onset lone atrial fibrillation
-
Christophersen IE, Holmegard HN, Jabbari J, Sajadieh A, Haunsø S, Tveit A, Svendsen JH, Olesen MS. Rare variants in GJA5 are associated with early-onset lone atrial fibrillation. Can J Cardiol. 2013;29:111-116.
-
(2013)
Can J Cardiol
, vol.29
, pp. 111-116
-
-
Christophersen, I.E.1
Holmegard, H.N.2
Jabbari, J.3
Sajadieh, A.4
Haunsø, S.5
Tveit, A.6
Svendsen, J.H.7
Olesen, M.S.8
-
28
-
-
84873141297
-
Prevalence and spectrum of GJA5 mutations associated with lone atrial fibrillation
-
Shi HF, Yang JF, Wang Q, Li RG, Xu YJ, Qu XK, Fang WY, Liu X, Yang YQ. Prevalence and spectrum of GJA5 mutations associated with lone atrial fibrillation. Mol Med Rep. 2013;7:767-774.
-
(2013)
Mol Med Rep
, vol.7
, pp. 767-774
-
-
Shi, H.F.1
Yang, J.F.2
Wang, Q.3
Li, R.G.4
Xu, Y.J.5
Qu, X.K.6
Fang, W.Y.7
Liu, X.8
Yang, Y.Q.9
-
29
-
-
84875491919
-
Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication
-
Sun Y, Yang YQ, Gong XQ, Wang XH, Li RG, Tan HW, Liu X, Fang WY, Bai D. Novel germline GJA5/connexin40 mutations associated with lone atrial fibrillation impair gap junctional intercellular communication. Hum Mutat. 2013;34:603-609.
-
(2013)
Hum Mutat
, vol.34
, pp. 603-609
-
-
Sun, Y.1
Yang, Y.Q.2
Gong, X.Q.3
Wang, X.H.4
Li, R.G.5
Tan, H.W.6
Liu, X.7
Fang, W.Y.8
Bai, D.9
-
30
-
-
77957734006
-
Novel connexin40 missense mutations in patients with familial atrial fibrillation
-
Yang YQ, Liu X, Zhang XL, Wang XH, Tan HW, Shi HF, Jiang WF, Fang WY. Novel connexin40 missense mutations in patients with familial atrial fibrillation. Europace. 2010;12:1421-1427.
-
(2010)
Europace
, vol.12
, pp. 1421-1427
-
-
Yang, Y.Q.1
Liu, X.2
Zhang, X.L.3
Wang, X.H.4
Tan, H.W.5
Shi, H.F.6
Jiang, W.F.7
Fang, W.Y.8
-
31
-
-
77957873979
-
Connexin40 nonsense mutation in familial atrial fibrillation
-
Yang YQ, Zhang XL, Wang XH, Tan HW, Shi HF, Jiang WF, Fang WY, Liu X. Connexin40 nonsense mutation in familial atrial fibrillation. Int J Mol Med. 2010;26:605-610.
-
(2010)
Int J Mol Med
, vol.26
, pp. 605-610
-
-
Yang, Y.Q.1
Zhang, X.L.2
Wang, X.H.3
Tan, H.W.4
Shi, H.F.5
Jiang, W.F.6
Fang, W.Y.7
Liu, X.8
-
32
-
-
84875156629
-
Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm
-
Müller II, Melville DB, Tanwar V, Rybski WM, Mukherjee A, Shoemaker MB, Wang WD, Schoenhard JA, Roden DM, Darbar D, Knapik EW, Hatzopoulos AK. Functional modeling in zebrafish demonstrates that the atrial-fibrillation- associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Dis Model Mech. 2013;6:332-341.
-
(2013)
Dis Model Mech
, vol.6
, pp. 332-341
-
-
Müller, I.I.1
Melville, D.B.2
Tanwar, V.3
Rybski, W.M.4
Mukherjee, A.5
Shoemaker, M.B.6
Wang, W.D.7
Schoenhard, J.A.8
Roden, D.M.9
Darbar, D.10
Knapik, E.W.11
Hatzopoulos, A.K.12
-
33
-
-
84880886873
-
Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation
-
Duhme N, Schweizer PA, Thomas D, Becker R, Schröter J, Barends TR, Schlichting I, Draguhn A, Bruehl C, Katus HA, Koenen M. Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation. Eur Heart J. 2013;34:2768-2775.
-
(2013)
Eur Heart J
, vol.34
, pp. 2768-2775
-
-
Duhme, N.1
Schweizer, P.A.2
Thomas, D.3
Becker, R.4
Schröter, J.5
Barends, T.R.6
Schlichting, I.7
Draguhn, A.8
Bruehl, C.9
Katus, H.A.10
Koenen, M.11
-
34
-
-
84888273529
-
Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization
-
Beavers DL, Wang W, Ather S, Voigt N, Garbino A, Dixit SS, Landstrom AP, Li N, Wang Q, Olivotto I, Dobrev D, Ackerman MJ, Wehrens XH. Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization. J Am Coll Cardiol. 2013;62:2010-2019.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 2010-2019
-
-
Beavers, D.L.1
Wang, W.2
Ather, S.3
Voigt, N.4
Garbino, A.5
Dixit, S.S.6
Landstrom, A.P.7
Li, N.8
Wang, Q.9
Olivotto, I.10
Dobrev, D.11
Ackerman, M.J.12
Wehrens, X.H.13
-
35
-
-
84878295837
-
Genetic variation in KCNA5: Impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation
-
Christophersen IE, Olesen MS, Liang B, Andersen MN, Larsen AP, Nielsen JB, Haunsø S, Olesen SP, Tveit A, Svendsen JH, Schmitt N. Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation. Eur Heart J. 2013;34:1517-1525.
-
(2013)
Eur Heart J
, vol.34
, pp. 1517-1525
-
-
Christophersen, I.E.1
Olesen, M.S.2
Liang, B.3
Andersen, M.N.4
Larsen, A.P.5
Nielsen, J.B.6
Haunsø, S.7
Olesen, S.P.8
Tveit, A.9
Svendsen, J.H.10
Schmitt, N.11
-
36
-
-
33745635351
-
Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation
-
Olson TM, Alekseev AE, Liu XK, Park S, Zingman LV, Bienengraeber M, Sattiraju S, Ballew JD, Jahangir A, Terzic A. Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation. Hum Mol Genet. 2006;15:2185-2191.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2185-2191
-
-
Olson, T.M.1
Alekseev, A.E.2
Liu, X.K.3
Park, S.4
Zingman, L.V.5
Bienengraeber, M.6
Sattiraju, S.7
Ballew, J.D.8
Jahangir, A.9
Terzic, A.10
-
37
-
-
67649536037
-
Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation
-
Yang YY, Li J, Lin X, et al. Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation. J Hum Genet. 2009;54:277-283.
-
(2009)
J Hum Genet
, vol.54
, pp. 277-283
-
-
Yang, Y.Y.1
Li, J.2
Lin, X.3
-
38
-
-
77956219434
-
Novel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillation
-
Yang T, Yang P, Roden DM, Darbar D. Novel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillation. Heart Rhythm. 2010;7:1246-1252.
-
(2010)
Heart Rhythm
, vol.7
, pp. 1246-1252
-
-
Yang, T.1
Yang, P.2
Roden, D.M.3
Darbar, D.4
-
39
-
-
84877958196
-
A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation
-
Olesen MS, Refsgaard L, Holst AG, Larsen AP, Grubb S, Haunsø S, Svendsen JH, Olesen SP, Schmitt N, Calloe K. A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation. Cardiovasc Res. 2013;98:488-495.
-
(2013)
Cardiovasc Res
, vol.98
, pp. 488-495
-
-
Olesen, M.S.1
Refsgaard, L.2
Holst, A.G.3
Larsen, A.P.4
Grubb, S.5
Haunsø, S.6
Svendsen, J.H.7
Olesen, S.P.8
Schmitt, N.9
Calloe, K.10
-
40
-
-
84859183376
-
Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation
-
Olesen MS, Bentzen BH, Nielsen JB, Steffensen AB, David JP, Jabbari J, Jensen HK, Haunsø S, Svendsen JH, Schmitt N. Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation. BMC Med Genet. 2012;13:24.
-
(2012)
BMC Med Genet
, vol.13
, pp. 24
-
-
Olesen, M.S.1
Bentzen, B.H.2
Nielsen, J.B.3
Steffensen, A.B.4
David, J.P.5
Jabbari, J.6
Jensen, H.K.7
Haunsø, S.8
Svendsen, J.H.9
Schmitt, N.10
-
41
-
-
6344292572
-
Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation
-
Yang Y, Xia M, Jin Q, et al. Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation. Am J Hum Genet. 2004;75:899-905.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 899-905
-
-
Yang, Y.1
Xia, M.2
Jin, Q.3
-
42
-
-
38349152549
-
KCNE3 mutation V17M identified in a patient with lone atrial fibrillation
-
Lundby A, Ravn LS, Svendsen JH, Hauns S, Olesen SP, Schmitt N. KCNE3 mutation V17M identified in a patient with lone atrial fibrillation. Cell Physiol Biochem. 2008;21:47-54.
-
(2008)
Cell Physiol Biochem
, vol.21
, pp. 47-54
-
-
Lundby, A.1
Ravn, L.S.2
Svendsen, J.H.3
Hauns, S.4
Olesen, S.P.5
Schmitt, N.6
-
43
-
-
39649099974
-
Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation
-
Ravn LS, Aizawa Y, Pollevick GD, Hofman-Bang J, Cordeiro JM, Dixen U, Jensen G, Wu Y, Burashnikov E, Haunso S, Guerchicoff A, Hu D, Svendsen JH, Christiansen M, Antzelevitch C. Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation. Heart Rhythm. 2008;5:427-435.
-
(2008)
Heart Rhythm
, vol.5
, pp. 427-435
-
-
Ravn, L.S.1
Aizawa, Y.2
Pollevick, G.D.3
Hofman-Bang, J.4
Cordeiro, J.M.5
Dixen, U.6
Jensen, G.7
Wu, Y.8
Burashnikov, E.9
Haunso, S.10
Guerchicoff, A.11
Hu, D.12
Svendsen, J.H.13
Christiansen, M.14
Antzelevitch, C.15
-
45
-
-
41849143324
-
The non-synonymous coding IKr-channel variant KCNH2-K897T is associated with atrial fibrillation: Results from a systematic candidate gene-based analysis of KCNH2 (HERG
-
Sinner MF, Pfeufer A, Akyol M, et al. The non-synonymous coding IKr-channel variant KCNH2-K897T is associated with atrial fibrillation: results from a systematic candidate gene-based analysis of KCNH2 (HERG). Eur Heart J. 2008;29:907-914.
-
(2008)
Eur Heart J
, vol.29
, pp. 907-914
-
-
Sinner, M.F.1
Pfeufer, A.2
Akyol, M.3
-
46
-
-
84875009425
-
KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia
-
Deo M, Ruan Y, Pandit SV, Shah K, Berenfeld O, Blaufox A, Cerrone M, Noujaim SF, Denegri M, Jalife J, Priori SG. KCNJ2 mutation in short QT syndrome 3 results in atrial fibrillation and ventricular proarrhythmia. Proc Natl Acad Sci U S A. 2013;110:4291-4296.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 4291-4296
-
-
Deo, M.1
Ruan, Y.2
Pandit, S.V.3
Shah, K.4
Berenfeld, O.5
Blaufox, A.6
Cerrone, M.7
Noujaim, S.F.8
Denegri, M.9
Jalife, J.10
Priori, S.G.11
-
47
-
-
20444372298
-
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation
-
Xia M, Jin Q, Bendahhou S, et al. A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun. 2005;332:1012-1019.
-
(2005)
Biochem Biophys Res Commun
, vol.332
, pp. 1012-1019
-
-
Xia, M.1
Jin, Q.2
Bendahhou, S.3
-
48
-
-
79955688385
-
Common polymorphisms in KCNJ5 [corrected] are associated with early-onset lone atrial fibrillation in Caucasians
-
Jabbari J, Olesen MS, Holst AG, Nielsen JB, Haunso S, Svendsen JH. Common polymorphisms in KCNJ5 [corrected] are associated with early-onset lone atrial fibrillation in Caucasians. Cardiology. 2011;118:116-120.
-
(2011)
Cardiology
, vol.118
, pp. 116-120
-
-
Jabbari, J.1
Olesen, M.S.2
Holst, A.G.3
Nielsen, J.B.4
Haunso, S.5
Svendsen, J.H.6
-
49
-
-
84866917269
-
A KCNJ8 mutation associated with early repolarization and atrial fibrillation
-
Delaney JT, Muhammad R, Blair MA, Kor K, Fish FA, Roden DM, Darbar D. A KCNJ8 mutation associated with early repolarization and atrial fibrillation. Europace. 2012;14:1428-1432.
-
(2012)
Europace
, vol.14
, pp. 1428-1432
-
-
Delaney, J.T.1
Muhammad, R.2
Blair, M.A.3
Kor, K.4
Fish, F.A.5
Roden, D.M.6
Darbar, D.7
-
50
-
-
65449138689
-
Comprehensive mutation scanning of LMNA in 268 patients with lone atrial fibrillation
-
Brauch KM, Chen LY, Olson TM. Comprehensive mutation scanning of LMNA in 268 patients with lone atrial fibrillation. Am J Cardiol. 2009;103:1426-1428.
-
(2009)
Am J Cardiol
, vol.103
, pp. 1426-1428
-
-
Brauch, K.M.1
Chen, L.Y.2
Olson, T.M.3
-
51
-
-
84859792490
-
Variants of the lamin A/C (LMNA) gene in non-valvular atrial fibrillation patients: A possible pathogenic role of the Thr528Met mutation
-
Saj M, Dabrowski R, Labib S, Jankowska A, Szperl M, Broda G, Szwed H, Tesson F, Bilinska ZT, Ploski R. Variants of the lamin A/C (LMNA) gene in non-valvular atrial fibrillation patients: a possible pathogenic role of the Thr528Met mutation. Mol Diagn Ther. 2012;16:99-107.
-
(2012)
Mol Diagn Ther
, vol.16
, pp. 99-107
-
-
Saj, M.1
Dabrowski, R.2
Labib, S.3
Jankowska, A.4
Szperl, M.5
Broda, G.6
Szwed, H.7
Tesson, F.8
Bilinska, Z.T.9
Ploski, R.10
-
52
-
-
84876145089
-
A novel NKX2.5 loss-of-function mutation responsible for familial atrial fibrillation
-
Huang RT, Xue S, Xu YJ, Zhou M, Yang YQ. A novel NKX2.5 loss-of-function mutation responsible for familial atrial fibrillation. Int J Mol Med. 2013;31:1119-1126.
-
(2013)
Int J Mol Med
, vol.31
, pp. 1119-1126
-
-
Huang, R.T.1
Xue, S.2
Xu, Y.J.3
Zhou, M.4
Yang, Y.Q.5
-
53
-
-
46949093558
-
Atrial natriuretic peptide frameshift mutation in familial atrial fibrillation
-
Hodgson-Zingman DM, Karst ML, Zingman LV, Heublein DM, Darbar D, Herron KJ, Ballew JD, de Andrade M, Burnett JC Jr., Olson TM. Atrial natriuretic peptide frameshift mutation in familial atrial fibrillation. N Engl J Med. 2008;359:158-165.
-
(2008)
N Engl J Med
, vol.359
, pp. 158-165
-
-
Hodgson-Zingman, D.M.1
Karst, M.L.2
Zingman, L.V.3
Heublein, D.M.4
Darbar, D.5
Herron, K.J.6
Ballew, J.D.7
De Andrade, M.8
Burnett Jr., J.C.9
Olson, T.M.10
-
54
-
-
77649181877
-
Identification of NPPA variants associated with atrial fibrillation in a Chinese GeneID population
-
Ren X, Xu C, Zhan C, et al. Identification of NPPA variants associated with atrial fibrillation in a Chinese GeneID population. Clin Chim Acta. 2010;411:481-485.
-
(2010)
Clin Chim Acta
, vol.411
, pp. 481-485
-
-
Ren, X.1
Xu, C.2
Zhan, C.3
-
55
-
-
57349179985
-
Mutation in nuclear pore component NUP155 leads to atrial fibrillation and early sudden cardiac death
-
Zhang X, Chen S, Yoo S, Chakrabarti S, Zhang T, Ke T, Oberti C, Yong SL, Fang F, Li L, de la Fuente R, Wang L, Chen Q, Wang QK. Mutation in nuclear pore component NUP155 leads to atrial fibrillation and early sudden cardiac death. Cell. 2008;135:1017-1027.
-
(2008)
Cell
, vol.135
, pp. 1017-1027
-
-
Zhang, X.1
Chen, S.2
Yoo, S.3
Chakrabarti, S.4
Zhang, T.5
Ke, T.6
Oberti, C.7
Yong, S.L.8
Fang, F.9
Li, L.10
De La Fuente, R.11
Wang, L.12
Chen, Q.13
Wang, Q.K.14
-
56
-
-
84883347914
-
A novel PITX2c loss-of-function mutation underlies lone atrial fibrillation
-
Zhou YM, Zheng PX, Yang YQ, Ge ZM, Kang WQ. A novel PITX2c loss-of-function mutation underlies lone atrial fibrillation. Int J Mol Med. 2013;32:827-834.
-
(2013)
Int J Mol Med
, vol.32
, pp. 827-834
-
-
Zhou, Y.M.1
Zheng, P.X.2
Yang, Y.Q.3
Ge, Z.M.4
Kang, W.Q.5
-
57
-
-
84881030282
-
S4153R is a gain-of-function mutation in the cardiac Ca 2+) release channel ryanodine receptor associated with catecholaminergic polymorphic ventricular tachycardia and paroxysmal atrial fibrillation
-
Zhabyeyev P, Hiess F, Wang R, Liu Y, Wayne Chen SR, Oudit GY. S4153R is a gain-of-function mutation in the cardiac Ca(2+) release channel ryanodine receptor associated with catecholaminergic polymorphic ventricular tachycardia and paroxysmal atrial fibrillation. Can J Cardiol. 2013;29:993-996.
-
(2013)
Can J Cardiol.
, Issue.29
, pp. 993-996
-
-
Zhabyeyev, P.1
Hiess, F.2
Wang, R.3
Liu, Y.4
Wayne Chen, S.R.5
Oudit, G.Y.6
-
58
-
-
84859971741
-
SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation
-
Olesen MS, Holst AG, Svendsen JH, Haunsø S, Tfelt-Hansen J. SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation. Heart Rhythm. 2012;9:770-773.
-
(2012)
Heart Rhythm
, vol.9
, pp. 770-773
-
-
Olesen, M.S.1
Holst, A.G.2
Svendsen, J.H.3
Haunsø, S.4
Tfelt-Hansen, J.5
-
59
-
-
70349451838
-
Mutations in sodium channel 1-and 2-subunits associated with atrial fibrillation
-
Watanabe H, Darbar D, Kaiser DW, Jiramongkolchai K, Chopra S, Donahue BS, Kannankeril PJ, Roden DM. Mutations in sodium channel 1-and 2-subunits associated with atrial fibrillation. Circ Arrhythm Electrophysiol. 2009;2:268-275.
-
(2009)
Circ Arrhythm Electrophysiol
, vol.2
, pp. 268-275
-
-
Watanabe, H.1
Darbar, D.2
Kaiser, D.W.3
Jiramongkolchai, K.4
Chopra, S.5
Donahue, B.S.6
Kannankeril, P.J.7
Roden, D.M.8
-
60
-
-
79951889503
-
Mutations in sodium channel -subunit SCN3B are associated with early-onset lone atrial fibrillation
-
Olesen MS, Jespersen T, Nielsen JB, Liang B, Møller DV, Hedley P, Christiansen M, Varró A, Olesen SP, Haunsø S, Schmitt N, Svendsen JH. Mutations in sodium channel -subunit SCN3B are associated with early-onset lone atrial fibrillation. Cardiovasc Res. 2011;89:786-793.
-
(2011)
Cardiovasc Res
, vol.89
, pp. 786-793
-
-
Olesen, M.S.1
Jespersen, T.2
Nielsen, J.B.3
Liang, B.4
Møller, D.V.5
Hedley, P.6
Christiansen, M.7
Varró, A.8
Olesen, S.P.9
Haunsø, S.10
Schmitt, N.11
Svendsen, J.H.12
-
61
-
-
77954761671
-
Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population
-
Wang P, Yang Q, Wu X, et al. Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population. Biochem Biophys Res Commun. 2010;398:98-104.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, pp. 98-104
-
-
Wang, P.1
Yang, Q.2
Wu, X.3
-
62
-
-
84878232651
-
Mutations of the SCN4B-encoded sodium channel 4 subunit in familial atrial fibrillation
-
Li RG, Wang Q, Xu YJ, Zhang M, Qu XK, Liu X, Fang WY, Yang YQ. Mutations of the SCN4B-encoded sodium channel 4 subunit in familial atrial fibrillation. Int J Mol Med. 2013;32:144-150.
-
(2013)
Int J Mol Med
, vol.32
, pp. 144-150
-
-
Li, R.G.1
Wang, Q.2
Xu, Y.J.3
Zhang, M.4
Qu, X.K.5
Liu, X.6
Fang, W.Y.7
Yang, Y.Q.8
-
63
-
-
42149147897
-
Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation
-
Darbar D, Kannankeril PJ, Donahue BS, Kucera G, Stubblefield T, Haines JL, George AL Jr., Roden DM. Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation. Circulation. 2008;117:1927-1935.
-
(2008)
Circulation
, vol.117
, pp. 1927-1935
-
-
Darbar, D.1
Kannankeril, P.J.2
Donahue, B.S.3
Kucera, G.4
Stubblefield, T.5
Haines, J.L.6
George Jr., A.L.7
Roden, D.M.8
-
64
-
-
37549043581
-
Cardiac sodium channel mutation in atrial fibrillation
-
Ellinor PT, Nam EG, Shea MA, Milan DJ, Ruskin JN, MacRae CA. Cardiac sodium channel mutation in atrial fibrillation. Heart Rhythm. 2008;5:99-105.
-
(2008)
Heart Rhythm
, vol.5
, pp. 99-105
-
-
Ellinor, P.T.1
Nam, E.G.2
Shea, M.A.3
Milan, D.J.4
Ruskin, J.N.5
Macrae, C.A.6
-
65
-
-
33645965922
-
SCN5A mutation associated with cardiac conduction defect and atrial arrhythmias
-
Laitinen-Forsblom PJ, Mäkynen P, Mäkynen H, Yli-Mäyry S, Virtanen V, Kontula K, Aalto-Setälä K. SCN5A mutation associated with cardiac conduction defect and atrial arrhythmias. J Cardiovasc Electrophysiol. 2006;17:480-485.
-
(2006)
J Cardiovasc Electrophysiol
, vol.17
, pp. 480-485
-
-
Laitinen-Forsblom, P.J.1
Mäkynen, P.2
Mäkynen, H.3
Yli-Mäyry, S.4
Virtanen, V.5
Kontula, K.6
Aalto-Setälä, K.7
-
66
-
-
59649130006
-
Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing
-
Li Q, Huang H, Liu G, Lam K, Rutberg J, Green MS, Birnie DH, Lemery R, Chahine M, Gollob MH. Gain-of-function mutation of Nav1.5 in atrial fibrillation enhances cellular excitability and lowers the threshold for action potential firing. Biochem Biophys Res Commun. 2009;380:132-137.
-
(2009)
Biochem Biophys Res Commun
, vol.380
, pp. 132-137
-
-
Li, Q.1
Huang, H.2
Liu, G.3
Lam, K.4
Rutberg, J.5
Green, M.S.6
Birnie, D.H.7
Lemery, R.8
Chahine, M.9
Gollob, M.H.10
-
67
-
-
53049092597
-
A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation
-
Makiyama T, Akao M, Shizuta S, Doi T, Nishiyama K, Oka Y, Ohno S, Nishio Y, Tsuji K, Itoh H, Kimura T, Kita T, Horie M. A novel SCN5A gain-of-function mutation M1875T associated with familial atrial fibrillation. J Am Coll Cardiol. 2008;52:1326-1334.
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 1326-1334
-
-
Makiyama, T.1
Akao, M.2
Shizuta, S.3
Doi, T.4
Nishiyama, K.5
Oka, Y.6
Ohno, S.7
Nishio, Y.8
Tsuji, K.9
Itoh, H.10
Kimura, T.11
Kita, T.12
Horie, M.13
-
68
-
-
84866643004
-
High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation
-
Olesen MS, Yuan L, Liang B, Holst AG, Nielsen N, Nielsen JB, Hedley PL, Christiansen M, Olesen SP, Haunsø S, Schmitt N, Jespersen T, Svendsen JH. High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation. Circ Cardiovasc Genet. 2012;5:450-459.
-
(2012)
Circ Cardiovasc Genet
, vol.5
, pp. 450-459
-
-
Olesen, M.S.1
Yuan, L.2
Liang, B.3
Holst, A.G.4
Nielsen, N.5
Nielsen, J.B.6
Hedley, P.L.7
Christiansen, M.8
Olesen, S.P.9
Haunsø, S.10
Schmitt, N.11
Jespersen, T.12
Svendsen, J.H.13
-
69
-
-
80052884048
-
Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model
-
Lemoine MD, Duverger JE, Naud P, Chartier D, Qi XY, Comtois P, Fabritz L, Kirchhof P, Nattel S. Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model. Cardiovasc Res. 2011;92:67-74.
-
(2011)
Cardiovasc Res
, vol.92
, pp. 67-74
-
-
Lemoine, M.D.1
Duverger, J.E.2
Naud, P.3
Chartier, D.4
Qi, X.Y.5
Comtois, P.6
Fabritz, L.7
Kirchhof, P.8
Nattel, S.9
-
70
-
-
67749099838
-
A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradation
-
Dickey DM, Yoder AR, Potter LR. A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradation. J Biol Chem. 2009;284:19196-19202.
-
(2009)
J Biol Chem
, vol.284
, pp. 19196-19202
-
-
Dickey, D.M.1
Yoder, A.R.2
Potter, L.R.3
-
71
-
-
0033529394
-
Promotion of atrial fibrillation by heart failure in dogs: Atrial remodeling of a different sort
-
Li D, Fareh S, Leung TK, Nattel S. Promotion of atrial fibrillation by heart failure in dogs: atrial remodeling of a different sort. Circulation. 1999;100:87-95.
-
(1999)
Circulation
, vol.100
, pp. 87-95
-
-
Li, D.1
Fareh, S.2
Leung, T.K.3
Nattel, S.4
-
72
-
-
84878024773
-
Autosomal recessive atrial dilated cardiomyopathy with standstill evolution associated with mutation of natriuretic peptide precursor A
-
Disertori M, Quintarelli S, Grasso M, et al. Autosomal recessive atrial dilated cardiomyopathy with standstill evolution associated with mutation of natriuretic peptide precursor A. Circ Cardiovasc Genet. 2013;6:27-36.
-
(2013)
Circ Cardiovasc Genet
, vol.6
, pp. 27-36
-
-
Disertori, M.1
Quintarelli, S.2
Grasso, M.3
-
73
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J. Complement factor H polymorphism in age-related macular degeneration. Science. 2005;308:385-389.
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
Sangiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
74
-
-
70749096913
-
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
-
Kathiresan S, Voight BF, Purcell S, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet. 2009;41:334-41.
-
(2009)
Nat Genet
, vol.41
, pp. 334-341
-
-
Kathiresan, S.1
Voight, B.F.2
Purcell, S.3
-
75
-
-
80053907554
-
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
-
Ehret GB, Munroe PB, Rice KM, et al. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478:103-109.
-
(2011)
Nature
, vol.478
, pp. 103-109
-
-
Ehret, G.B.1
Munroe, P.B.2
Rice, K.M.3
-
76
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
Willer CJ, Schmidt EM, Sengupta S, et al. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013;45:1274-1283.
-
(2013)
Nat Genet
, vol.45
, pp. 1274-1283
-
-
Willer, C.J.1
Schmidt, E.M.2
Sengupta, S.3
-
77
-
-
75749122164
-
Several common variants modulate heart rate PR interval and QRS duration
-
Holm H, Gudbjartsson DF, Arnar DO, et al. Several common variants modulate heart rate, PR interval and QRS duration. Nat Genet. 2010;42:117-122.
-
(2010)
Nat Genet
, vol.42
, pp. 117-122
-
-
Holm, H.1
Gudbjartsson, D.F.2
Arnar, D.O.3
-
78
-
-
84891629514
-
A common variant on chromosome 4q25 is associated with prolonged PR interval in subjects with and without atrial fibrillation
-
Kolek MJ, Parvez B, Muhammad R, Shoemaker MB, Blair MA, Stubblefield T, Kucera GA, Denny JC, Roden DM, Darbar D. A common variant on chromosome 4q25 is associated with prolonged PR interval in subjects with and without atrial fibrillation. Am J Cardiol. 2014;113:309-313.
-
(2014)
Am J Cardiol
, vol.113
, pp. 309-313
-
-
Kolek, M.J.1
Parvez, B.2
Muhammad, R.3
Shoemaker, M.B.4
Blair, M.A.5
Stubblefield, T.6
Kucera, G.A.7
Denny, J.C.8
Roden, D.M.9
Darbar, D.10
-
79
-
-
75749097235
-
Genome-wide association study of PR interval
-
Pfeufer A, van Noord C, Marciante KD, et al. Genome-wide association study of PR interval. Nat Genet. 2010;42:153-159.
-
(2010)
Nat Genet
, vol.42
, pp. 153-159
-
-
Pfeufer, A.1
Van Noord, C.2
Marciante, K.D.3
-
80
-
-
63449136073
-
Common variants at ten loci influence QT interval duration in the QTGEN Study
-
Newton-Cheh C, Eijgelsheim M, Rice KM, et al. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet. 2009;41:399-406.
-
(2009)
Nat Genet
, vol.41
, pp. 399-406
-
-
Newton-Cheh, C.1
Eijgelsheim, M.2
Rice, K.M.3
-
81
-
-
63449109595
-
Common variants at ten loci modulate the QT interval duration in the QTSCD Study
-
Pfeufer A, Sanna S, Arking DE, et al. Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat Genet. 2009;41:407-414.
-
(2009)
Nat Genet
, vol.41
, pp. 407-414
-
-
Pfeufer, A.1
Sanna, S.2
Arking, D.E.3
-
82
-
-
79952257689
-
Genome-wide association studies of the PR interval in African Americans
-
Candidate-Gene Association Resource (CARe) Consortium
-
Smith JG, Magnani JW, Palmer C, et al.; Candidate-Gene Association Resource (CARe) Consortium. Genome-wide association studies of the PR interval in African Americans. PLoS Genet. 2011;7:e1001304.
-
(2011)
PLoS Genet
, vol.7
-
-
Smith, J.G.1
Magnani, J.W.2
Palmer, C.3
-
83
-
-
34447515621
-
Variants conferring risk of atrial fibrillation on chromosome 4q25
-
Gudbjartsson DF, Arnar DO, Helgadottir A, et al. Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature. 2007;448:353-357.
-
(2007)
Nature
, vol.448
, pp. 353-357
-
-
Gudbjartsson, D.F.1
Arnar, D.O.2
Helgadottir, A.3
-
84
-
-
64849095095
-
Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation
-
Kääb S, Darbar D, van Noord C, et al. Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J. 2009;30:813-819.
-
(2009)
Eur Heart J
, vol.30
, pp. 813-819
-
-
Kääb, S.1
Darbar, D.2
Van Noord, C.3
-
85
-
-
54349123606
-
Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population
-
Viviani Anselmi C, Novelli V, Roncarati R, Malovini A, Bellazzi R, Bronzini R, Marchese G, Condorelli G, Montenero AS, Puca AA. Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population. Heart. 2008;94:1394-1396.
-
(2008)
Heart
, vol.94
, pp. 1394-1396
-
-
Viviani Anselmi, C.1
Novelli, V.2
Roncarati, R.3
Malovini, A.4
Bellazzi, R.5
Bronzini, R.6
Marchese, G.7
Condorelli, G.8
Montenero, A.S.9
Puca, A.A.10
-
86
-
-
71449120890
-
Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population
-
Shi L, Li C, Wang C, et al. Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population. Hum Genet. 2009;126:843-849.
-
(2009)
Hum Genet
, vol.126
, pp. 843-849
-
-
Shi, L.1
Li, C.2
Wang, C.3
-
87
-
-
84857512783
-
Characterization of genome-wide association-identified variants for atrial fibrillation in African Americans
-
Delaney JT, Jeff JM, Brown NJ, Pretorius M, Okafor HE, Darbar D, Roden DM, Crawford DC. Characterization of genome-wide association-identified variants for atrial fibrillation in African Americans. PLoS One. 2012;7:e32338.
-
(2012)
PLoS One
, vol.7
-
-
Delaney, J.T.1
Jeff, J.M.2
Brown, N.J.3
Pretorius, M.4
Okafor, H.E.5
Darbar, D.6
Roden, D.M.7
Crawford, D.C.8
-
88
-
-
55849100349
-
Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke
-
Gretarsdottir S, Thorleifsson G, Manolescu A, et al. Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. Ann Neurol. 2008;64:402-409.
-
(2008)
Ann Neurol
, vol.64
, pp. 402-409
-
-
Gretarsdottir, S.1
Thorleifsson, G.2
Manolescu, A.3
-
89
-
-
77956419347
-
The association of the 4q25 susceptibility variant for atrial fibrillation with stroke is limited to stroke of cardioembolic etiology
-
International Stroke Genetics Consortium
-
Lemmens R, Buysschaert I, Geelen V, et al.; International Stroke Genetics Consortium. The association of the 4q25 susceptibility variant for atrial fibrillation with stroke is limited to stroke of cardioembolic etiology. Stroke. 2010;41:1850-1857.
-
(2010)
Stroke
, vol.41
, pp. 1850-1857
-
-
Lemmens, R.1
Buysschaert, I.2
Geelen, V.3
-
90
-
-
79957965470
-
Uncovering an intermediate phenotype associated with rs2200733 at 4q25 in lone atrial fibrillation
-
Goodloe AH, Herron KJ, Olson TM. Uncovering an intermediate phenotype associated with rs2200733 at 4q25 in lone atrial fibrillation. Am J Cardiol. 2011;107:1802-1805.
-
(2011)
Am J Cardiol
, vol.107
, pp. 1802-1805
-
-
Goodloe, A.H.1
Herron, K.J.2
Olson, T.M.3
-
91
-
-
84861636519
-
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
-
Ellinor PT, Lunetta KL, Albert CM, et al. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012;44:670-675.
-
(2012)
Nat Genet
, vol.44
, pp. 670-675
-
-
Ellinor, P.T.1
Lunetta, K.L.2
Albert, C.M.3
-
92
-
-
77957270569
-
Independent susceptibility markers for atrial fibrillation on chromosome 4q25
-
Lubitz SA, Sinner MF, Lunetta KL, et al. Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation. 2010;122:976-984.
-
(2010)
Circulation
, vol.122
, pp. 976-984
-
-
Lubitz, S.A.1
Sinner, M.F.2
Lunetta, K.L.3
-
93
-
-
0032493860
-
Pitx2 participates in the late phase of the pathway controlling left-right asymmetry
-
Piedra ME, Icardo JM, Albajar M, Rodriguez-Rey JC, Ros MA. Pitx2 participates in the late phase of the pathway controlling left-right asymmetry. Cell. 1998;94:319-324.
-
(1998)
Cell
, vol.94
, pp. 319-324
-
-
Piedra, M.E.1
Icardo, J.M.2
Albajar, M.3
Rodriguez-Rey, J.C.4
Rosenberg, M.A.5
-
94
-
-
0034954830
-
Regulation of leftright asymmetry by thresholds of Pitx2c activity
-
Liu C, Liu W, Lu MF, Brown NA, Martin JF. Regulation of leftright asymmetry by thresholds of Pitx2c activity. Development. 2001;128:2039-2048.
-
(2001)
Development
, vol.128
, pp. 2039-2048
-
-
Liu, C.1
Liu, W.2
Lu, M.F.3
Brown, N.A.4
Martin, J.F.5
-
95
-
-
0033575873
-
Function of Rieger syndrome gene in left-right asymmetry and craniofacial development
-
Lu MF, Pressman C, Dyer R, Johnson RL, Martin JF. Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature. 1999;401:276-278.
-
(1999)
Nature
, vol.401
, pp. 276-278
-
-
Lu, M.F.1
Pressman, C.2
Dyer, R.3
Johnson, R.L.4
Martin, J.F.5
-
96
-
-
0033575971
-
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis
-
Lin CR, Kioussi C, O'Connell S, Briata P, Szeto D, Liu F, Izpisúa-Belmonte JC, Rosenfeld MG. Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis. Nature. 1999;401: 279-282.
-
(1999)
Nature
, vol.401
, pp. 279-282
-
-
Lin, C.R.1
Kioussi, C.2
O'Connell, S.3
Briata, P.4
Szeto, D.5
Liu, F.6
Izpisúa-Belmonte, J.C.7
Rosenfeld, M.G.8
-
97
-
-
0033387975
-
Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra-and periocular mesoderm and right pulmonary isomerism
-
Kitamura K, Miura H, Miyagawa-Tomita S, Yanazawa M, Katoh-Fukui Y, Suzuki R, Ohuchi H, Suehiro A, Motegi Y, Nakahara Y, Kondo S, YokoyaMohammed M.A. Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra-and periocular mesoderm and right pulmonary isomerism. Development. 1999;126:5749-5758.
-
(1999)
Development
, vol.126
, pp. 5749-5758
-
-
Kitamura, K.1
Miura, H.2
Miyagawa-Tomita, S.3
Yanazawa, M.4
Katoh-Fukui, Y.5
Suzuki, R.6
Ohuchi, H.7
Suehiro, A.8
Motegi, Y.9
Nakahara, Y.10
Kondo, S.11
YokoyaMohammed, M.A.12
-
98
-
-
79959714035
-
PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression
-
Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld HH, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA. PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression. Circ Cardiovasc Genet. 2011;4:123-133.
-
(2011)
Circ Cardiovasc Genet
, vol.4
, pp. 123-133
-
-
Kirchhof, P.1
Kahr, P.C.2
Kaese, S.3
Piccini, I.4
Vokshi, I.5
Scheld, H.H.6
Rotering, H.7
Fortmueller, L.8
Laakmann, S.9
Verheule, S.10
Schotten, U.11
Fabritz, L.12
Brown, N.A.13
-
99
-
-
37349083151
-
Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium
-
Mommersteeg MT, Brown NA, Prall OW, de Gier-de Vries C, Harvey RP, Moorman AF, Christoffels VM. Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium. Circ Res. 2007;101:902-909.
-
(2007)
Circ Res
, vol.101
, pp. 902-909
-
-
Mommersteeg, M.T.1
Brown, N.A.2
Prall, O.W.3
De Gier-De Vries, C.4
Harvey, R.P.5
Moorman, A.F.6
Christoffels, V.M.7
-
100
-
-
33847020703
-
Molecular pathway for the localized formation of the sinoatrial node
-
Mommersteeg MT, Hoogaars WM, Prall OW, de Gier-de Vries C, Wiese C, Clout DE, Papaioannou VE, Brown NA, Harvey RP, Moorman AF, Christoffels VM. Molecular pathway for the localized formation of the sinoatrial node. Circ Res. 2007;100:354-362.
-
(2007)
Circ Res
, vol.100
, pp. 354-362
-
-
Mommersteeg, M.T.1
Hoogaars, W.M.2
Prall, O.W.3
De Gier-De Vries, C.4
Wiese, C.5
Clout, D.E.6
Papaioannou, V.E.7
Brown, N.A.8
Harvey, R.P.9
Moorman, A.F.10
Christoffels, V.M.11
-
101
-
-
80052758502
-
PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis
-
Chinchilla A, Daimi H, Lozano-Velasco E, Dominguez JN, Caballero R, Delpón E, Tamargo J, Cinca J, Hove-Madsen L, Aranega AE, Franco D. PITX2 insufficiency leads to atrial electrical and structural remodeling linked to arrhythmogenesis. Circ Cardiovasc Genet. 2011;4:269-279.
-
(2011)
Circ Cardiovasc Genet
, vol.4
, pp. 269-279
-
-
Chinchilla, A.1
Daimi, H.2
Lozano-Velasco, E.3
Dominguez, J.N.4
Caballero, R.5
Delpón, E.6
Tamargo, J.7
Cinca, J.8
Hove-Madsen, L.9
Aranega, A.E.10
Franco, D.11
-
102
-
-
84897056784
-
Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes
-
Tao Y, Zhang M, Li L, Bai Y, Zhou Y, Moon AM, Kaminski HJ, Martin JF. Pitx2, an atrial fibrillation predisposition gene, directly regulates ion transport and intercalated disc genes. Circ Cardiovasc Genet. 2014;7(1):23-32.
-
(2014)
Circ Cardiovasc Genet
, vol.7
, Issue.1
, pp. 23-32
-
-
Tao, Y.1
Zhang, M.2
Li, L.3
Bai, Y.4
Zhou, Y.5
Moon, A.M.6
Kaminski, H.J.7
Martin, J.F.8
-
103
-
-
68149165772
-
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry
-
Benjamin EJ, Rice KM, Arking DE, et al. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009;41:879-881.
-
(2009)
Nat Genet
, vol.41
, pp. 879-881
-
-
Benjamin, E.J.1
Rice, K.M.2
Arking, D.E.3
-
104
-
-
68149137739
-
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke
-
Gudbjartsson DF, Holm H, Gretarsdottir S, et al. A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. Nat Genet. 2009;41:876-878.
-
(2009)
Nat Genet
, vol.41
, pp. 876-878
-
-
Gudbjartsson, D.F.1
Holm, H.2
Gretarsdottir, S.3
-
105
-
-
29644443953
-
Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation
-
Jung CG, Kim HJ, Kawaguchi M, Khanna KK, Hida H, Asai K, Nishino H, Miura Y. Homeotic factor ATBF1 induces the cell cycle arrest associated with neuronal differentiation. Development. 2005;132:5137-5145.
-
(2005)
Development
, vol.132
, pp. 5137-5145
-
-
Jung, C.G.1
Kim, H.J.2
Kawaguchi, M.3
Khanna, K.K.4
Hida, H.5
Asai, K.6
Nishino, H.7
Miura, Y.8
-
106
-
-
0035816607
-
Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1
-
Berry FB, Miura Y, Mihara K, Kaspar P, Sakata N, Hashimoto-Tamaoki T, Tamaoki T. Positive and negative regulation of myogenic differentiation of C2C12 cells by isoforms of the multiple homeodomain zinc finger transcription factor ATBF1. J Biol Chem. 2001;276:25057-25065.
-
(2001)
J Biol Chem
, vol.276
, pp. 25057-25065
-
-
Berry, F.B.1
Miura, Y.2
Mihara, K.3
Kaspar, P.4
Sakata, N.5
Hashimoto-Tamaoki, T.6
Tamaoki, T.7
-
107
-
-
20144389099
-
Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer
-
Sun X, Frierson HF, Chen C, Li C, Ran Q, Otto KB, Cantarel BL, Cantarel BM, Vessella RL, Gao AC, Petros J, Miura Y, Simons JW, Dong JT. Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer. Nat Genet. 2005;37:407-412.
-
(2005)
Nat Genet
, vol.37
, pp. 407-412
-
-
Sun, X.1
Frierson, H.F.2
Chen, C.3
Li, C.4
Ran, Q.5
Otto, K.B.6
Cantarel, B.L.7
Cantarel, B.M.8
Vessella, R.L.9
Gao, A.C.10
Petros, J.11
Miura, Y.12
Simons, J.W.13
Dong, J.T.14
-
108
-
-
41149083903
-
Down-regulation of ATBF1 is a major inactivating mechanism in hepatocellular carcinoma
-
Kim CJ, Song JH, Cho YG, Cao Z, Lee YS, Nam SW, Lee JY, Park WS. Down-regulation of ATBF1 is a major inactivating mechanism in hepatocellular carcinoma. Histopathology. 2008;52:552-559.
-
(2008)
Histopathology
, vol.52
, pp. 552-559
-
-
Kim, C.J.1
Song, J.H.2
Cho, Y.G.3
Cao, Z.4
Lee, Y.S.5
Nam, S.W.6
Lee, J.Y.7
Park, W.S.8
-
109
-
-
0342995754
-
Cloning of the cDNA encoding the mouse ATBF1 transcription factor
-
Ido A, Miura Y, Watanabe M, Sakai M, Inoue Y, Miki T, Hashimoto T, Morinaga T, Nishi S, Tamaoki T. Cloning of the cDNA encoding the mouse ATBF1 transcription factor. Gene. 1996;168:227-231.
-
(1996)
Gene
, vol.168
, pp. 227-231
-
-
Ido, A.1
Miura, Y.2
Watanabe, M.3
Sakai, M.4
Inoue, Y.5
Miki, T.6
Hashimoto, T.7
Morinaga, T.8
Nishi, S.9
Tamaoki, T.10
-
110
-
-
77649191092
-
Common variants in KCNN3 are associated with lone atrial fibrillation
-
Ellinor PT, Lunetta KL, Glazer NL, et al. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010;42:240-244.
-
(2010)
Nat Genet
, vol.42
, pp. 240-244
-
-
Ellinor, P.T.1
Lunetta, K.L.2
Glazer, N.L.3
-
111
-
-
0029796983
-
Small-conductance, calcium-activated potassium channels from mammalian brain
-
Köhler M, Hirschberg B, Bond CT, Kinzie JM, Marrion NV, Maylie J, Adelman JP. Small-conductance, calcium-activated potassium channels from mammalian brain. Science. 1996;273:1709-1714.
-
(1996)
Science
, vol.273
, pp. 1709-1714
-
-
Köhler, M.1
Hirschberg, B.2
Bond, C.T.3
Kinzie, J.M.4
Marrion, N.V.5
Maylie, J.6
Adelman, J.P.7
-
112
-
-
61649127297
-
Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation
-
Li N, Timofeyev V, Tuteja D, Xu D, Lu L, Zhang Q, Zhang Z, Singapuri A, Albert TR, Rajagopal AV, Bond CT, Periasamy M, Adelman J, Chiamvimonvat N. Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation. J Physiol. 2009;587:1087-1100.
-
(2009)
J Physiol
, vol.587
, pp. 1087-1100
-
-
Li, N.1
Timofeyev, V.2
Tuteja, D.3
Xu, D.4
Lu, L.5
Zhang, Q.6
Zhang, Z.7
Singapuri, A.8
Albert, T.R.9
Rajagopal, A.V.10
Bond, C.T.11
Periasamy, M.12
Adelman, J.13
Chiamvimonvat, N.14
-
113
-
-
77956662777
-
Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation
-
Diness JG, Sørensen US, Nissen JD, Al-Shahib B, Jespersen T, Grunnet M, Hansen RS. Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation. Circ Arrhythm Electrophysiol. 2010;3:380-390.
-
(2010)
Circ Arrhythm Electrophysiol
, vol.3
, pp. 380-390
-
-
Diness, J.G.1
Sørensen, U.S.2
Nissen, J.D.3
Al-Shahib, B.4
Jespersen, T.5
Grunnet, M.6
Hansen, R.S.7
-
114
-
-
84895062166
-
Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog
-
Qi XY, Diness JG, Brundel BJ, Zhou XB, Naud P, Wu CT, Huang H, Harada M, Aflaki M, Dobrev D, Grunnet M, Nattel S. Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog. Circulation. 2014;129:430-440.
-
(2014)
Circulation
, vol.129
, pp. 430-440
-
-
Qi, X.Y.1
Diness, J.G.2
Brundel, B.J.3
Zhou, X.B.4
Naud, P.5
Wu, C.T.6
Huang, H.7
Harada, M.8
Aflaki, M.9
Dobrev, D.10
Grunnet, M.11
Nattel, S.12
-
115
-
-
84893145398
-
Critical roles of a small conductance Ca+-activated K+ channel (SK3) in the repolarization process of atrial myocytes
-
Zhang XD, Timofeyev V, Li N, Myers RE, Zhang DM, Singapuri A, Lau VC, Bond CT, Adelman J, Lieu DK, Chiamvimonvat N. Critical roles of a small conductance Ca+-activated K+ channel (SK3) in the repolarization process of atrial myocytes. Cardiovasc Res. 2014;101:317-325.
-
(2014)
Cardiovasc Res
, vol.101
, pp. 317-325
-
-
Zhang, X.D.1
Timofeyev, V.2
Li, N.3
Myers, R.E.4
Zhang, D.M.5
Singapuri, A.6
Lau, V.C.7
Bond, C.T.8
Adelman, J.9
Lieu, D.K.10
Chiamvimonvat, N.11
-
116
-
-
84893040871
-
Overexpression of KCNN3 results in sudden cardiac death
-
Mahida S, Mills RW, Tucker NR, Simonson B, Macri V, Lemoine MD, Das S, Milan DJ, Ellinor PT. Overexpression of KCNN3 results in sudden cardiac death. Cardiovasc Res. 2014;101:326-334.
-
(2014)
Cardiovasc Res
, vol.101
, pp. 326-334
-
-
Mahida, S.1
Mills, R.W.2
Tucker, N.R.3
Simonson, B.4
Macri, V.5
Lemoine, M.D.6
Das, S.7
Milan, D.J.8
Ellinor, P.T.9
-
117
-
-
0036807496
-
Agnathia-otocephaly complex: Report of three cases with involvement of two different Carnegie stages
-
Schiffer C, Tariverdian G, Schiesser M, Thomas MC, Sergi C. Agnathia-otocephaly complex: report of three cases with involvement of two different Carnegie stages. Am J Med. Genet. 2002;112:203-208.
-
(2002)
Am J Med. Genet
, vol.112
, pp. 203-208
-
-
Schiffer, C.1
Tariverdian, G.2
Schiesser, M.3
Thomas, M.C.4
Sergi, C.5
-
118
-
-
84875508330
-
Recurrent agnathia-otocephaly caused by DNA replication slippage in PRRX1
-
Dasouki M, Andrews B, Parimi P, Kamnasaran D. Recurrent agnathia-otocephaly caused by DNA replication slippage in PRRX1. Am J Med. Genet A. 2013;161A:803-808.
-
(2013)
Am J Med. Genet A
, vol.161 A
, pp. 803-808
-
-
Dasouki, M.1
Andrews, B.2
Parimi, P.3
Kamnasaran, D.4
-
119
-
-
0029026227
-
The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages
-
Martin JF, Bradley A, Olson EN. The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. Genes Dev. 1995;9:1237-1249.
-
(1995)
Genes Dev
, vol.9
, pp. 1237-1249
-
-
Martin, J.F.1
Bradley, A.2
Olson, E.N.3
-
120
-
-
0034004138
-
Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus
-
Bergwerff M, Gittenberger-de Groot AC, Wisse LJ, DeRuiter MC, Wessels A, Martin JF, Olson EN, Kern MJ. Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus. Virchows Arch. 2000;436:12-19.
-
(2000)
Virchows Arch
, vol.436
, pp. 12-19
-
-
Bergwerff, M.1
Gittenberger-De Groot, A.C.2
Wisse, L.J.3
Deruiter, M.C.4
Wessels, A.5
Martin, J.F.6
Olson, E.N.7
Kern, M.J.8
-
121
-
-
2942659832
-
Paired-related homeobox gene Prx1 is required for pulmonary vascular development
-
Ihida-Stansbury K, McKean DM, Gebb SA, Martin JF, Stevens T, Nemenoff R, Akeson A, Vaughn J, Jones PL. Paired-related homeobox gene Prx1 is required for pulmonary vascular development. Circ Res. 2004;94:1507-1514.
-
(2004)
Circ Res
, vol.94
, pp. 1507-1514
-
-
Ihida-Stansbury, K.1
McKean, D.M.2
Gebb, S.A.3
Martin, J.F.4
Stevens, T.5
Nemenoff, R.6
Akeson, A.7
Vaughn, J.8
Jones, P.L.9
-
122
-
-
0037637420
-
Pacemaker channel dysfunction in a patient with sinus node disease
-
Schulze-Bahr E, Neu A, Friederich P, Kaupp UB, Breithardt G, Pongs O, Isbrandt D. Pacemaker channel dysfunction in a patient with sinus node disease. J Clin Invest. 2003;111:1537-1545.
-
(2003)
J Clin Invest
, vol.111
, pp. 1537-1545
-
-
Schulze-Bahr, E.1
Neu, A.2
FriederiPan, C.H.3
Kaupp, U.B.4
Breithardt, G.5
Pongs, O.6
Isbrandt, D.7
-
123
-
-
3042549234
-
Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia
-
Ueda K, Nakamura K, Hayashi T, et al. Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia. J Biol Chem. 2004;279:27194-27198.
-
(2004)
J Biol Chem
, vol.279
, pp. 27194-27198
-
-
Ueda, K.1
Nakamura, K.2
Hayashi, T.3
-
124
-
-
30444452695
-
Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel
-
Milanesi R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D. Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel. N Engl J Med. 2006;354:151-157.
-
(2006)
N Engl J Med
, vol.354
, pp. 151-157
-
-
Milanesi, R.1
Baruscotti, M.2
Gnecchi-Ruscone, T.3
Difrancesco, D.4
-
125
-
-
32444447144
-
Involvement of lipid rafts and caveolae in cardiac ion channel function
-
Maguy A, Hebert TE, Nattel S. Involvement of lipid rafts and caveolae in cardiac ion channel function. Cardiovasc Res. 2006;69:798-807.
-
(2006)
Cardiovasc Res
, vol.69
, pp. 798-807
-
-
Maguy, A.1
Hebert, T.E.2
Nattel, S.3
-
126
-
-
33847729462
-
Caveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries
-
Adebiyi A, Zhao G, Cheranov SY, Ahmed A, Jaggar JH. Caveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries. Am J Physiol Heart Circ Physiol. 2007;292:H1584-H1592.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Adebiyi, A.1
Zhao, G.2
Cheranov, S.Y.3
Ahmed, A.4
Jaggar, J.H.5
-
127
-
-
0037143769
-
Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice
-
Zhao YY, Liu Y, Stan RV, Fan L, Gu Y, Dalton N, Chu PH, Peterson K, Ross J Jr., Chien KR. Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci U S A. 2002;99:11375-11380.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11375-11380
-
-
Zhao, Y.Y.1
Liu, Y.2
Stan, R.V.3
Fan, L.4
Gu, Y.5
Dalton, N.6
Chu, P.H.7
Peterson, K.8
Ross Jr., J.9
Chien, K.R.10
-
128
-
-
67649844282
-
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice
-
Lei K, Zhang X, Ding X, Guo X, Chen M, Zhu B, Xu T, Zhuang Y, Xu R, Han M. SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A. 2009;106:10207-10212.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 10207-10212
-
-
Lei, K.1
Zhang, X.2
Ding, X.3
Guo, X.4
Chen, M.5
Zhu, B.6
Xu, T.7
Zhuang, Y.8
Xu, R.9
Han, M.10
-
129
-
-
46749099446
-
Nesprin-2 Giant (NUANCE maintains nuclear envelope architecture and composition in skin
-
Lüke Y, Zaim H, Karakesisoglou I, Jaeger VM, Sellin L, Lu W, Schneider M, Neumann S, Beijer A, Munck M, Padmakumar VC, Gloy J, Walz G, Noegel AA. Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci. 2008;121:1887-1898.
-
(2008)
J Cell Sci
, vol.121
, pp. 1887-1898
-
-
Lüke, Y.1
Zaim, H.2
Karakesisoglou, I.3
Jaeger, V.M.4
Sellin, L.5
Lu, W.6
Schneider, M.7
Neumann, S.8
Beijer, A.9
Munck, M.10
Padmakumar, V.C.11
Gloy, J.12
Walz, G.13
Noegel, A.A.14
-
130
-
-
70350211470
-
SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice
-
Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M. SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009;64:173-187.
-
(2009)
Neuron
, vol.64
, pp. 173-187
-
-
Zhang, X.1
Lei, K.2
Yuan, X.3
Wu, X.4
Zhuang, Y.5
Xu, T.6
Xu, R.7
Han, M.8
-
131
-
-
35748935532
-
Nesprin-1 and-2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity
-
Zhang Q, Bethmann C, Worth NF, et al. Nesprin-1 and-2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity. Hum Mol Genet. 2007;16:2816-2833.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2816-2833
-
-
Zhang, Q.1
Bethmann, C.2
Worth, N.F.3
-
132
-
-
84893068848
-
Gene expression and genetic variation in human atria
-
Lin H, Dolmatova EV, Morley MP, Lunetta KL, McManus DD, Magnani JW, Margulies KB, Hakonarson H, del Monte F, Benjamin EJ, Cappola TP, Ellinor PT. Gene expression and genetic variation in human atria. Heart Rhythm. 2014;11:266-271.
-
(2014)
Heart Rhythm
, vol.11
, pp. 266-271
-
-
Lin, H.1
Dolmatova, E.V.2
Morley, M.P.3
Lunetta, K.L.4
McManus, D.D.5
Magnani, J.W.6
Margulies, K.B.7
Hakonarson, H.8
Del Monte, F.9
Benjamin, E.J.10
Cappola, T.P.11
Ellinor, P.T.12
-
133
-
-
0035852783
-
Myozenin: An alpha-actinin-and gamma-filamin-binding protein of skeletal muscle Z lines
-
Takada F, Vander Woude DL, Tong HQ, Thompson TG, Watkins SC, Kunkel LM, Beggs AH. Myozenin: an alpha-actinin-and gamma-filamin-binding protein of skeletal muscle Z lines. Proc Natl Acad Sci U S A. 2001;98:1595-1600.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1595-1600
-
-
Takada, F.1
Vander WouDavison, D.E.L.2
Tong, H.Q.3
Thompson, T.G.4
Watkins, S.C.5
Kunkel, L.M.6
Beggs, A.H.7
-
134
-
-
34147182155
-
Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy
-
Osio A, Tan L, Chen SN, Lombardi R, Nagueh SF, Shete S, Roberts R, Willerson JT, Marian AJ. Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy. Circ Res. 2007;100:766-768.
-
(2007)
Circ Res
, vol.100
, pp. 766-768
-
-
Osio, A.1
Tan, L.2
Chen, S.N.3
Lombardi, R.4
Nagueh, S.F.5
Shete, S.6
Roberts, R.7
Willerson, J.T.8
Marian, A.J.9
-
135
-
-
19944423058
-
Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress
-
Frey N, Barrientos T, Shelton JM, Frank D, Rütten H, Gehring D, Kuhn C, Lutz M, Rothermel B, Bassel-Duby R, Richardson JA, Katus HA, Hill JA, Olson EN. Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress. Nat Med. 2004;10:1336-1343.
-
(2004)
Nat Med
, vol.10
, pp. 1336-1343
-
-
Frey, N.1
Barrientos, T.2
Shelton, J.M.3
Frank, D.4
Rütten, H.5
Gehring, D.6
Kuhn, C.7
Lutz, M.8
Rothermel, B.9
Bassel-Duby, R.10
Richardson, J.A.11
Katus, H.A.12
Hill, J.A.13
Olson, E.N.14
-
136
-
-
84881257862
-
Novel genetic markers improve measures of atrial fibrillation risk prediction
-
Everett BM, Cook NR, Conen D, Chasman DI, Ridker PM, Albert CM. Novel genetic markers improve measures of atrial fibrillation risk prediction. Eur Heart J. 2013;34:2243-2251.
-
(2013)
Eur Heart J
, vol.34
, pp. 2243-2251
-
-
Everett, B.M.1
Cook, N.R.2
Conen, D.3
Chasman, D.I.4
Ridker, P.M.5
Albert, C.M.6
-
137
-
-
84896908605
-
Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese
-
Lubitz SA, Lunetta KL, Lin H, et al. Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. J Am Coll Cardiol. 2014;63(12):1200-1210.
-
(2014)
J Am Coll Cardiol
, vol.63
, Issue.12
, pp. 1200-1210
-
-
Lubitz, S.A.1
Lunetta, K.L.2
Lin, H.3
-
138
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
Musunuru K, Strong A, Frank-Kamenetsky M, et al. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature. 2010;466:714-719.
-
(2010)
Nature
, vol.466
, pp. 714-719
-
-
Musunuru, K.1
Strong, A.2
Frank-Kamenetsky, M.3
-
139
-
-
42649125570
-
Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass
-
Petretto E, Sarwar R, Grieve I, et al. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet. 2008;40:546-552.
-
(2008)
Nat Genet
, vol.40
, pp. 546-552
-
-
Petretto, E.1
Sarwar, R.2
Grieve, I.3
-
140
-
-
42649105447
-
Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease
-
Monti J, Fischer J, Paskas S, et al. Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. Nat Genet. 2008;40:529-537.
-
(2008)
Nat Genet
, vol.40
, pp. 529-537
-
-
Monti, J.1
Fischer, J.2
Paskas, S.3
-
141
-
-
84878682420
-
The Genotype-Tissue Expression (GTEx) project
-
The Genotype-Tissue Expression (GTEx) project. Nat Genet. 2013; 45:580-585.
-
(2013)
Nat Genet
, vol.45
, pp. 580-585
-
-
-
142
-
-
80051710052
-
HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: This document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA
-
Heart Rhythm Society (HRS); European Heart Rhythm Association (EHRA
-
Ackerman MJ, Priori SG, Willems S, et al.; Heart Rhythm Society (HRS); European Heart Rhythm Association (EHRA). HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA). Europace. 2011; 13:1077-1109.
-
(2011)
Europace
, vol.13
, pp. 1077-1109
-
-
Ackerman, M.J.1
Priori, S.G.2
Willems, S.3
-
143
-
-
79957589237
-
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations
-
O'Roak BJ, Deriziotis P, Lee C, et al. Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations. Nat Genet. 2011;43:585-589.
-
(2011)
Nat Genet
, vol.43
, pp. 585-589
-
-
O'Roak, B.J.1
Deriziotis, P.2
Lee, C.3
-
144
-
-
84883541181
-
Common genetic polymorphism at 4q25 locus predicts atrial fibrillation recurrence after successful cardioversion
-
Parvez B, Shoemaker MB, Muhammad R, Richardson R, Jiang L, Blair MA, Roden DM, Darbar D. Common genetic polymorphism at 4q25 locus predicts atrial fibrillation recurrence after successful cardioversion. Heart Rhythm. 2013;10:849-855.
-
(2013)
Heart Rhythm
, vol.10
, pp. 849-855
-
-
Parvez, B.1
Shoemaker, M.B.2
Muhammad, R.3
Richardson, R.4
Jiang, L.5
Blair, M.A.6
Roden, D.M.7
Darbar, D.8
-
145
-
-
76449100572
-
Chromosome 4q25 variants and atrial fibrillation recurrence after catheter ablation
-
Husser D, Adams V, Piorkowski C, Hindricks G, Bollmann A. Chromosome 4q25 variants and atrial fibrillation recurrence after catheter ablation. J Am Coll Cardiol. 2010;55:747-753.
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 747-753
-
-
Husser, D.1
Adams, V.2
Piorkowski, C.3
Hindricks, G.4
Bollmann, A.5
-
146
-
-
84875368330
-
Common atrial fibrillation risk alleles at 4q25 predict recurrence after catheter-based atrial fibrillation ablation
-
Benjamin Shoemaker M, Muhammad R, Parvez B, et al. Common atrial fibrillation risk alleles at 4q25 predict recurrence after catheter-based atrial fibrillation ablation. Heart Rhythm. 2013;10:394-400.
-
(2013)
Heart Rhythm
, vol.10
, pp. 394-400
-
-
Benjamin Shoemaker, M.1
Muhammad, R.2
Parvez, B.3
-
147
-
-
84864763384
-
Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation
-
Parvez B, Vaglio J, Rowan S, Muhammad R, Kucera G, Stubblefield T, Carter S, Roden D, Darbar D. Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation. J Am Coll Cardiol. 2012;60:539-545.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 539-545
-
-
Parvez, B.1
Vaglio, J.2
Rowan, S.3
Muhammad, R.4
Kucera, G.5
Stubblefield, T.6
Carter, S.7
Roden, D.8
Darbar, D.9
-
148
-
-
60649118584
-
Development of a risk score for atrial fibrillation (Framingham Heart Study): A community-based cohort study
-
Schnabel RB, Sullivan LM, Levy D, et al. Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study. Lancet. 2009;373:739-745.
-
(2009)
Lancet
, vol.373
, pp. 739-745
-
-
Schnabel, R.B.1
Sullivan, L.M.2
Levy, D.3
-
149
-
-
70449337406
-
N-terminal pro-B-type natriuretic peptide is a major predictor of the development of atrial fibrillation: The Cardiovascular Health Study
-
Patton KK, Ellinor PT, Heckbert SR, Christenson RH, DeFilippi C, Gottdiener JS, Kronmal RA. N-terminal pro-B-type natriuretic peptide is a major predictor of the development of atrial fibrillation: the Cardiovascular Health Study. Circulation. 2009;120:1768-1774.
-
(2009)
Circulation
, vol.120
, pp. 1768-1774
-
-
Patton, K.K.1
Ellinor, P.T.2
Heckbert, S.R.3
Christenson, R.H.4
Defilippi, C.5
Gottdiener, J.S.6
Kronmal, R.A.7
|