Identification of a genetic locus for familial atrial fibrillation

New England Journal of Medicine

Volumn 336, Issue 13, 1997, Pages 905-911

  Brugada, Ramon ^a   Tapscott, Terry ^a   Czernuszewicz, Grazyna Z ^a   Marian, A J ^a   Iglesias, Anna ^a   Mont, Lluis ^b   Brugada, Josep ^b   Girona, Josep ^c   Domingo, Anna ^c   Bachinski, Linda L ^a   Roberts, Robert ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF BARCELONA   (Spain)

^c HOSPITAL MATERNO INFANTIL VALL D HEBRON   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHROMOSOME 10Q; CLINICAL ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; ELECTROCARDIOGRAPHY; FAMILIAL DISEASE; FEMALE; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; HAPLOTYPE; HEART ATRIUM FIBRILLATION; HUMAN; MALE; PRIORITY JOURNAL; SPAIN;

ADULT; ATRIAL FIBRILLATION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 10; DINUCLEOTIDE REPEATS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENE AMPLIFICATION; GENES, DOMINANT; GENETIC MARKERS; HUMANS; LINKAGE (GENETICS); LOD SCORE; MALE; MUTATION; PEDIGREE;

EID: 0031004845     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199703273361302     Document Type: Article

References (15)

1. The National Heart, Lung, and Blood Institute Working Group on Atrial Fibrillation. Atrial fibrillation: current understandings and research imperatives. J Am Coll Cardiol 1993;22:1830-4.
2. Feinberg WM, Blackshear JL, Laupacis A, Kronmal R, Hart RG. Prevalence, age distribution, and gender of patients with atrial fibrillation: analysis and implications. Arch Intern Med 1995;155:469-73.
3. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation: a major contributor to stroke in the elderly: the Framingham Study. Arch Intern Med 1987; 147:1561-4.
4. Albers GW. Atrial fibrillation and stroke: three new studies, three remaining questions. Arch Intern Med 1994;154:1443-8.
5. Beyer F, Paul T, Luhmer I, Bertram H, Kallfelz HC. Familiäres idiopathisches Vorhofflimmern mit Bradyarrhythmie. Z Kardiol 1993;82:674-7.
6. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16: 1215.
7. Neitzel H. A routine method for the establishment of permanent growing lymphoblastoid cell lines. Hum Genet 1986;73:320-6.
8. Weissenbach J, Gyapay G, Dib C, et al. A second-generation linkage map of the human genome. Nature 1992;359:794-801.
9. NIH/CEPH Collaborative Mapping Group. A comprehensive genetic linkage map of the human genome. Science 1992;258:67-86.
10. Durand JB, Bachinski LL, Bieling LC, et al. Localization of a gene responsible for familial dilated cardiomyopathy to chromosome lq32. Circulation 1995;92:3387-9.
11. Ott J. Analysis of human genetic linkage. Rev. ed. Baltimore: Johns Hopkins University Press, 1991.
12. Scott DA, Carmi R, Elbedour K, Yosefsberg S, Stone EM, Sheffield VC. An autosomal recessive nonsyndromic-hearing-loss locus identified by DNA pooling using two inbred Bedouin kindreds. Am J Hum Genet 1996;59:385-91.
13. Hoehe M, Berrettini W, Leppert M, et al. Genetic mapping of adrenergic receptor genes. Am J Hum Genet 1989;45:Suppl:A143. abstract.
14. Yang-Feng TL, Xue FY, Zhong WW, et al. Chromosomal organization of adrenergic receptor genes. Proc Natl Acad Sci U S A 1990;87:1516-20.
15. Bullrich F, Druck T, Kunapuli P, et al. Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRKS and GRK6. Cytogenet Cell Genet 1995;70:250-4.