High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation

Circulation: Cardiovascular Genetics

Volumn 5, Issue 4, 2012, Pages 450-459

  Olesen, Morten S ^a,b   Yuan, Lei ^a,c   Liang, Bo ^a,c   Hols, Anders G ^a,b   Nielsen, Nikolaj ^a,c   Nielsen, Jonas B ^a,b   Hedley, Paula L ^c   Christiansen, Michael ^c   Olesen, Søren Peter ^a,c   Haunsø, Stig ^a,b,d   Schmitt, Nicole ^a,c   Jespersen, Thomas ^a,c   Svendsen, Jesper H ^a,b,d  

^a DANISH NATIONAL RESEARCH FOUNDATION   (Denmark)

^b University of Copenhagen   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Atrial fibrillation; Genes; Long QT syndrome; QT interval electrocardiography; SCN5A

Indexed keywords

COMPLEMENTARY DNA; GENOMIC DNA; SODIUM CHANNEL NAV1.5;

ADULT; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; ECHOCARDIOGRAPHY; FEMALE; GENE MUTATION; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART CONDUCTION; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HUMAN; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; ONSET AGE; PATCH CLAMP; PREVALENCE; PRIORITY JOURNAL; QT INTERVAL; SINGLE NUCLEOTIDE POLYMORPHISM; SODIUM CURRENT;

AGE OF ONSET; AMINO ACID SEQUENCE; ATRIAL FIBRILLATION; BASE SEQUENCE; COHORT STUDIES; COMPUTATIONAL BIOLOGY; DENMARK; DNA MUTATIONAL ANALYSIS; FAMILY; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HUMANS; LONG QT SYNDROME; MOLECULAR SEQUENCE DATA; MUTATION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL;

EID: 84866643004     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.111.962597     Document Type: Article

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