Camalexin-induced apoptosis in prostate cancer cells involves alterations of expression and activity of lysosomal protease cathepsin d

Molecules

Volumn 19, Issue 4, 2014, Pages 3988-4005

  Smith, Basil ^a   Randle, Diandra ^a   Mezencev, Roman ^b   Thomas, LeeShawn ^c   Hinton, Cimona ^a   Odero Marah, Valerie ^a  

^a CLARK ATLANTA UNIVERSITY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c FLORIDA A AND M UNIVERSITY   (United States)

Author keywords

Camalexin; Cathepsin D; Lysosomes; Phytoalexins; Prostate cancer

Indexed keywords

ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; CAMALEXIN; CATHEPSIN D; CTSD PROTEIN, HUMAN; INDOLE DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PLANT EXTRACT; PROTEIN BAX; PROTEIN P53; THIAZOLE DERIVATIVE;

ANTIBODY SPECIFICITY; APOPTOSIS; ARABIDOPSIS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; LYSOSOME; MALE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PROSTATE; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ARABIDOPSIS; BCL-2-ASSOCIATED X PROTEIN; CATHEPSIN D; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; INDOLES; LYSOSOMES; MALE; ORGAN SPECIFICITY; OXIDATIVE STRESS; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; PROSTATE; SIGNAL TRANSDUCTION; THIAZOLES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84899509608     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19043988     Document Type: Article

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