Camalexin induces apoptosis in T-leukemia Jurkat cells by increased concentration of reactive oxygen species and activation of caspase-8 and caspase-9

Journal of Natural Medicines

Volumn 65, Issue 3-4, 2011, Pages 488-499

  Mezencev, Roman ^a   Updegrove, Taylor ^a   Kutschy, Peter ^b   Repovská, Mária ^b   McDonald, John F ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b P J AFÁRIK UNIVERSITY   (Slovakia)

Author keywords

Apoptosis; Camalexin; Leukemia; Phytoalexin; Reactive oxygen species; ROS

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BUTHIONINE SULFOXIMINE; CAMALEXIN; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; DICHLORODIHYDROFLUORESCEIN DIACETATE; GLUTATHIONE; HYDROETHIDINE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL SUBPOPULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOCHEMISTRY; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG POTENCY; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME ACTIVATION; FIBROBLAST; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOBLAST; MITOCHONDRIAL MEMBRANE POTENTIAL; PHYTOCHEMISTRY; T CELL LEUKEMIA; TIME;

APOPTOSIS; CASPASE 8; CASPASE 9; CELL CYCLE; CELLS, CULTURED; ENZYME ACTIVATION; GLUTATHIONE; HUMANS; INDOLES; JURKAT CELLS; LEUKEMIA, T-CELL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR STRUCTURE; REACTIVE OXYGEN SPECIES; SUPEROXIDES; THIAZOLES;

EID: 79960440317     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-011-0526-x     Document Type: Article

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