The phytoalexin camalexin mediates cytotoxicity towards aggressive prostate cancer cells via reactive oxygen species

Journal of Natural Medicines

Volumn 67, Issue 3, 2013, Pages 607-618

  Smith, Basil A ^a   Neal, Corey L ^a   Chetram, Mahandranauth ^a   Vo, Baohan ^a   Mezencev, Roman ^b   Hinton, Cimona ^a   Odero Marah, Valerie A ^a  

^a CLARK ATLANTA UNIVERSITY   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Apoptosis; Camalexin; Prostate cancer; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CAMALEXIN; CASPASE 3; CASPASE 7; COMPLEMENTARY DNA; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR SNAIL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CELL MIGRATION; CELL SPECIFICITY; CELL STRAIN ARCAP; CELL STRAIN C4 2; CELL STRAIN LNCAP; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; EPITHELIAL MESENCHYMAL TRANSITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MALE; OXIDATIVE STRESS; PROSTATE CANCER; STABLE TRANSFECTION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; INDOLES; MALE; NEOPLASM INVASIVENESS; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SESQUITERPENES; THIAZOLES; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 84879244516     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-012-0722-3     Document Type: Article

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