-
1
-
-
33645774635
-
Nodal dissection for patients with gastric cancer: A randomised controlled trial
-
[PMID: 16574546 DOI: 10.1016/ S1470-2045(06)70623-4]
-
Wu CW, Hsiung CA, Lo SS, Hsieh MC, Chen JH, Li AF, Lui WY, Whang-Peng J. Nodal dissection for patients with gastric cancer: a randomised controlled trial. Lancet Oncol 2006; 7: 309-315 [PMID: 16574546 DOI: 10.1016/ S1470-2045(06)70623-4]
-
(2006)
Lancet Oncol
, vol.7
, pp. 309-315
-
-
Wu, C.W.1
Hsiung, C.A.2
Lo, S.S.3
Hsieh, M.C.4
Chen, J.H.5
Li, A.F.6
Lui, W.Y.7
Whang-Peng, J.8
-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
[PMID: 21376230 DOI: 10.1016/j.cell.2011.02.013]
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674 [PMID: 21376230 DOI: 10.1016/j.cell.2011.02.013]
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
35448961939
-
The Warburg effect and its cancer therapeutic implications
-
[PMID: 17551814 DOI: 10.1007/ s10863-007-9086-x]
-
Chen Z, Lu W, Garcia-Prieto C, Huang P. The Warburg effect and its cancer therapeutic implications. J Bioenerg Biomembr 2007; 39: 267-274 [PMID: 17551814 DOI: 10.1007/ s10863-007-9086-x]
-
(2007)
J Bioenerg Biomembr
, vol.39
, pp. 267-274
-
-
Chen, Z.1
Lu, W.2
Garcia-Prieto, C.3
Huang, P.4
-
6
-
-
84874118537
-
The Warburg effect: Insights from the past decade
-
[PMID: 23159371 DOI: 10.1016/j.pharmthera.2012.11.003]
-
Upadhyay M, Samal J, Kandpal M, Singh OV, Vivekanandan P. The Warburg effect: insights from the past decade. Pharmacol Ther 2013; 137: 318-330 [PMID: 23159371 DOI: 10.1016/j.pharmthera.2012.11.003]
-
(2013)
Pharmacol Ther
, vol.137
, pp. 318-330
-
-
Upadhyay, M.1
Samal, J.2
Kandpal, M.3
Singh, O.V.4
Vivekanandan, P.5
-
7
-
-
22044442733
-
Mitochondrial genome instability and mtDNA depletion in human cancers
-
[PMID: 15965052 DOI: 10.1196/annals. 1338.011]
-
Lee HC, Yin PH, Lin JC, Wu CC, Chen CY, Wu CW, Chi CW, Tam TN, Wei YH. Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci 2005; 1042: 109-122 [PMID: 15965052 DOI: 10.1196/annals. 1338.011]
-
(2005)
Ann N Y Acad Sci
, vol.1042
, pp. 109-122
-
-
Lee, H.C.1
Yin, P.H.2
Lin, J.C.3
Wu, C.C.4
Chen, C.Y.5
Wu, C.W.6
Chi, C.W.7
Tam, T.N.8
Wei, Y.H.9
-
8
-
-
61449091362
-
Mitochondrial DNA instability and metabolic shift in human cancers
-
[PMID: 19333428 DOI: 10.3390/ijms10020674]
-
Lee HC, Wei YH. Mitochondrial DNA instability and metabolic shift in human cancers. Int J Mol Sci 2009; 10: 674-701 [PMID: 19333428 DOI: 10.3390/ijms10020674]
-
(2009)
Int J Mol Sci
, vol.10
, pp. 674-701
-
-
Lee, H.C.1
Wei, Y.H.2
-
9
-
-
77957938682
-
Somatic mutations of mitochondrial DNA in aging and cancer progression
-
[PMID: 20816876 DOI: 10.1016/ j.arr.2010.08.009]
-
Lee HC, Chang CM, Chi CW. Somatic mutations of mitochondrial DNA in aging and cancer progression. Ageing Res Rev 2010; 9 Suppl 1: S47-S58 [PMID: 20816876 DOI: 10.1016/ j.arr.2010.08.009]
-
(2010)
Ageing Res Rev
, vol.9
, Issue.SUPPL. 1
-
-
Lee, H.C.1
Chang, C.M.2
Chi, C.W.3
-
10
-
-
84866665390
-
Mitochondria and cancer
-
[PMID: 23001348 DOI: 10.1038/nrc3365]
-
Wallace DC. Mitochondria and cancer. Nat Rev Cancer 2012; 12: 685-698 [PMID: 23001348 DOI: 10.1038/nrc3365]
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 685-698
-
-
Wallace, D.C.1
-
11
-
-
84875868055
-
A mitochondrial bioenergetic etiology of disease
-
[PMID: 23543062 DOI: 10.1172/JCI61398]
-
Wallace DC. A mitochondrial bioenergetic etiology of disease. J Clin Invest 2013; 123: 1405-1412 [PMID: 23543062 DOI: 10.1172/JCI61398]
-
(2013)
J Clin Invest
, vol.123
, pp. 1405-1412
-
-
Wallace, D.C.1
-
12
-
-
84869397441
-
Human mitochondrial DNA: Roles of inherited and somatic mutations
-
[PMID: 23154810 DOI: 10.1038/ nrg3275]
-
Schon EA, DiMauro S, Hirano M. Human mitochondrial DNA: roles of inherited and somatic mutations. Nat Rev Genet 2012; 13: 878-890 [PMID: 23154810 DOI: 10.1038/ nrg3275]
-
(2012)
Nat Rev Genet
, vol.13
, pp. 878-890
-
-
Schon, E.A.1
Dimauro, S.2
Hirano, M.3
-
13
-
-
23044514580
-
Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer
-
[PMID: 15892105 DOI: 10.1002/gcc.20213]
-
Wu CW, Yin PH, Hung WY, Li AF, Li SH, Chi CW, Wei YH, Lee HC. Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer. Genes Chromosomes Cancer 2005; 44: 19-28 [PMID: 15892105 DOI: 10.1002/gcc.20213]
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 19-28
-
-
Wu, C.W.1
Yin, P.H.2
Hung, W.Y.3
Li, A.F.4
Li, S.H.5
Chi, C.W.6
Wei, Y.H.7
Lee, H.C.8
-
14
-
-
41449085168
-
Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region
-
[PMID: 18252697 DOI: 10.1093/mutage/gen002]
-
Hung WY, Lin JC, Lee LM, Wu CW, Tseng LM, Yin PH, Chi CW, Lee HC. Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region. Mutagenesis 2008; 23: 137-142 [PMID: 18252697 DOI: 10.1093/mutage/gen002]
-
(2008)
Mutagenesis
, vol.23
, pp. 137-142
-
-
Hung, W.Y.1
Lin, J.C.2
Lee, L.M.3
Wu, C.W.4
Tseng, L.M.5
Yin, P.H.6
Chi, C.W.7
Lee, H.C.8
-
15
-
-
76749101102
-
Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer
-
[PMID: 19527772 DOI: 10.1016/j.bbagen.2009.06.006]
-
Hung WY, Wu CW, Yin PH, Chang CJ, Li AF, Chi CW, Wei YH, Lee HC. Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer. Biochim Biophys Acta 2010; 1800: 264-270 [PMID: 19527772 DOI: 10.1016/j.bbagen.2009.06.006]
-
(2010)
Biochim Biophys Acta
, vol.1800
, pp. 264-270
-
-
Hung, W.Y.1
Wu, C.W.2
Yin, P.H.3
Chang, C.J.4
Li, A.F.5
Chi, C.W.6
Wei, Y.H.7
Lee, H.C.8
-
16
-
-
0347286859
-
Somatic mitochondrial DNA mutations in adult-onset leukaemia
-
[PMID: 14523470 DOI: 10.1038/sj.leu.2403146]
-
He L, Luo L, Proctor SJ, Middleton PG, Blakely EL, Taylor RW, Turnbull DM. Somatic mitochondrial DNA mutations in adult-onset leukaemia. Leukemia 2003; 17: 2487-2491 [PMID: 14523470 DOI: 10.1038/sj.leu.2403146]
-
(2003)
Leukemia
, vol.17
, pp. 2487-2491
-
-
He, L.1
Luo, L.2
Proctor, S.J.3
Middleton, P.G.4
Blakely, E.L.5
Taylor, R.W.6
Turnbull, D.M.7
-
17
-
-
0039250954
-
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
-
[PMID: 10720328 DOI: 10.1126/science. 287.5460.2017]
-
Fliss MS, Usadel H, Caballero OL, Wu L, Buta MR, Eleff SM, Jen J, Sidransky D. Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 2000; 287: 2017-2019 [PMID: 10720328 DOI: 10.1126/science. 287.5460.2017]
-
(2000)
Science
, vol.287
, pp. 2017-2019
-
-
Fliss, M.S.1
Usadel, H.2
Caballero, O.L.3
Wu, L.4
Buta, M.R.5
Eleff, S.M.6
Jen, J.7
Sidransky, D.8
-
18
-
-
0035886843
-
Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates
-
[PMID: 11606403]
-
Parrella P, Xiao Y, Fliss M, Sanchez-Cespedes M, Mazzarelli P, Rinaldi M, Nicol T, Gabrielson E, Cuomo C, Cohen D, Pandit S, Spencer M, Rabitti C, Fazio VM, Sidransky D. Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. Cancer Res 2001; 61: 7623-7626 [PMID: 11606403]
-
(2001)
Cancer Res
, vol.61
, pp. 7623-7626
-
-
Parrella, P.1
Xiao, Y.2
Fliss, M.3
Sanchez-Cespedes, M.4
Mazzarelli, P.5
Rinaldi, M.6
Nicol, T.7
Gabrielson, E.8
Cuomo, C.9
Cohen, D.10
Pandit, S.11
Spencer, M.12
Rabitti, C.13
Fazio, V.M.14
Sidransky, D.15
-
19
-
-
0036170578
-
Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer
-
[PMID: 11861366]
-
Tan DJ, Bai RK, Wong LJ. Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res 2002; 62: 972-976 [PMID: 11861366]
-
(2002)
Cancer Res
, vol.62
, pp. 972-976
-
-
Tan, D.J.1
Bai, R.K.2
Wong, L.J.3
-
20
-
-
13444283964
-
Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid
-
[PMID: 15375011 DOI: 10.1093/carcin/bgh282]
-
Zhu W, Qin W, Bradley P, Wessel A, Puckett CL, Sauter ER. Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid. Carcinogenesis 2005; 26: 145-152 [PMID: 15375011 DOI: 10.1093/carcin/bgh282]
-
(2005)
Carcinogenesis
, vol.26
, pp. 145-152
-
-
Zhu, W.1
Qin, W.2
Bradley, P.3
Wessel, A.4
Puckett, C.L.5
Sauter, E.R.6
-
21
-
-
80051570214
-
Somatic mutations of the mitochondrial genome in human breast cancers
-
[PMID: 21748819 DOI: 10.1002/gcc.20901]
-
Tseng LM, Yin PH, Yang CW, Tsai YF, Hsu CY, Chi CW, Lee HC. Somatic mutations of the mitochondrial genome in human breast cancers. Genes Chromosomes Cancer 2011; 50: 800-811 [PMID: 21748819 DOI: 10.1002/gcc.20901]
-
(2011)
Genes Chromosomes Cancer
, vol.50
, pp. 800-811
-
-
Tseng, L.M.1
Yin, P.H.2
Yang, C.W.3
Tsai, Y.F.4
Hsu, C.Y.5
Chi, C.W.6
Lee, H.C.7
-
22
-
-
33646559185
-
Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer
-
[PMID: 16620376 DOI: 10.1186/1471-2407-6-93]
-
Tan DJ, Chang J, Liu LL, Bai RK, Wang YF, Yeh KT, Wong LJ. Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer. BMC Cancer 2006; 6: 93 [PMID: 16620376 DOI: 10.1186/1471-2407-6-93]
-
(2006)
BMC Cancer
, vol.6
, pp. 93
-
-
Tan, D.J.1
Chang, J.2
Liu, L.L.3
Bai, R.K.4
Wang, Y.F.5
Yeh, K.T.6
Wong, L.J.7
-
23
-
-
33846144801
-
Mitochondrial DNA mutations in differentiated thyroid cancer with respect to the age factor
-
[PMID: 17171498 DOI: 10.1007/s00268-005-0447-5]
-
Witte J, Lehmann S, Wulfert M, Yang Q, Röher HD. Mitochondrial DNA mutations in differentiated thyroid cancer with respect to the age factor. World J Surg 2007; 31: 51-59 [PMID: 17171498 DOI: 10.1007/s00268-005-0447-5]
-
(2007)
World J Surg
, vol.31
, pp. 51-59
-
-
Witte, J.1
Lehmann, S.2
Wulfert, M.3
Yang, Q.4
Röher, H.D.5
-
24
-
-
3042766311
-
Molecular alterations in mitochondrial DNA of hepatocellular carcinomas: Is there a correlation with clinicopathological profile?
-
[PMID: 15121793 DOI: 10.1136/ jmg.2003.013532]
-
Wong LJ, Tan DJ, Bai RK, Yeh KT, Chang J. Molecular alterations in mitochondrial DNA of hepatocellular carcinomas: is there a correlation with clinicopathological profile? J Med Genet 2004; 41: e65 [PMID: 15121793 DOI: 10.1136/ jmg.2003.013532]
-
(2004)
J Med Genet
, vol.e65
, pp. 41
-
-
Wong, L.J.1
Tan, D.J.2
Bai, R.K.3
Yeh, K.T.4
Chang, J.5
-
25
-
-
76349101416
-
Somatic mutations of mitochondrial genome in hepatocellular carcinoma
-
[PMID: 20006738 DOI: 10.1016/j.mito.2009.12.147]
-
Yin PH, Wu CC, Lin JC, Chi CW, Wei YH, Lee HC. Somatic mutations of mitochondrial genome in hepatocellular carcinoma. Mitochondrion 2010; 10: 174-182 [PMID: 20006738 DOI: 10.1016/j.mito.2009.12.147]
-
(2010)
Mitochondrion
, vol.10
, pp. 174-182
-
-
Yin, P.H.1
Wu, C.C.2
Lin, J.C.3
Chi, C.W.4
Wei, Y.H.5
Lee, H.C.6
-
26
-
-
34548127859
-
Relationship between mitochondrial DNA mutations and clinical characteristics in human lung cancer
-
[PMID: 17707697 DOI: 10.1016/ j.mito.2007.06.003]
-
Jin X, Zhang J, Gao Y, Ding K, Wang N, Zhou D, Jen J, Cheng S. Relationship between mitochondrial DNA mutations and clinical characteristics in human lung cancer. Mitochondrion 2007; 7: 347-353 [PMID: 17707697 DOI: 10.1016/ j.mito.2007.06.003]
-
(2007)
Mitochondrion
, vol.7
, pp. 347-353
-
-
Jin, X.1
Zhang, J.2
Gao, Y.3
Ding, K.4
Wang, N.5
Zhou, D.6
Jen, J.7
Cheng, S.8
-
27
-
-
0041742269
-
Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients
-
[PMID: 12873974]
-
Wong LJ, Lueth M, Li XN, Lau CC, Vogel H. Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients. Cancer Res 2003; 63: 3866-3871 [PMID: 12873974]
-
(2003)
Cancer Res
, vol.63
, pp. 3866-3871
-
-
Wong, L.J.1
Lueth, M.2
Li, X.N.3
Lau, C.C.4
Vogel, H.5
-
28
-
-
77950679964
-
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization
-
[PMID: 20028790 DOI: 10.1093/hmg/ddp566]
-
Porcelli AM, Ghelli A, Ceccarelli C, Lang M, Cenacchi G, Capristo M, Pennisi LF, Morra I, Ciccarelli E, Melcarne A, Bartoletti-Stella A, Salfi N, Tallini G, Martinuzzi A, Carelli V, Attimonelli M, Rugolo M, Romeo G, Gasparre G. The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization. Hum Mol Genet 2010; 19: 1019-1032 [PMID: 20028790 DOI: 10.1093/hmg/ddp566]
-
(2010)
Hum Mol Genet
, vol.19
, pp. 1019-1032
-
-
Porcelli, A.M.1
Ghelli, A.2
Ceccarelli, C.3
Lang, M.4
Cenacchi, G.5
Capristo, M.6
Pennisi, L.F.7
Morra, I.8
Ciccarelli, E.9
Melcarne, A.10
Bartoletti-Stella, A.11
Salfi, N.12
Tallini, G.13
Martinuzzi, A.14
Carelli, V.15
Attimonelli, M.16
Rugolo, M.17
Romeo, G.18
Gasparre, G.19
-
29
-
-
34547480470
-
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors
-
[PMID: 17517629 DOI: 10.1073/pnas]
-
Gasparre G, Porcelli AM, Bonora E, Pennisi LF, Toller M, Iommarini L, Ghelli A, Moretti M, Betts CM, Martinelli GN, Ceroni AR, Curcio F, Carelli V, Rugolo M, Tallini G, Romeo G. Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors. Proc Natl Acad Sci USA 2007; 104: 9001-9006 [PMID: 17517629 DOI: 10.1073/pnas]
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 9001-9006
-
-
Gasparre, G.1
Porcelli, A.M.2
Bonora, E.3
Pennisi, L.F.4
Toller, M.5
Iommarini, L.6
Ghelli, A.7
Moretti, M.8
Betts, C.M.9
Martinelli, G.N.10
Ceroni, A.R.11
Curcio, F.12
Carelli, V.13
Rugolo, M.14
Tallini, G.15
Romeo, G.16
-
30
-
-
2342481620
-
Somatic mitochondrial DNA mutations in oral cancer of betel quid chewers
-
[PMID: 15126307 DOI: 10.1196/annals.1293.030]
-
Tan DJ, Chang J, Chen WL, Agress LJ, Yeh KT, Wang B, Wong LJ. Somatic mitochondrial DNA mutations in oral cancer of betel quid chewers. Ann N Y Acad Sci 2004; 1011: 310-316 [PMID: 15126307 DOI: 10.1196/annals.1293.030]
-
(2004)
Ann N Y Acad Sci
, vol.1011
, pp. 310-316
-
-
Tan, D.J.1
Chang, J.2
Chen, W.L.3
Agress, L.J.4
Yeh, K.T.5
Wang, B.6
Wong, L.J.7
-
31
-
-
84879047947
-
Clinical significance in oral cavity squamous cell carcinoma of pathogenic somatic mitochondrial mutations
-
[PMID: 23799027 DOI: 10.1371/journal. pone.0065578]
-
Lai CH, Huang SF, Liao CT, Chen IH, Wang HM, Hsieh LL. Clinical significance in oral cavity squamous cell carcinoma of pathogenic somatic mitochondrial mutations. PLoS One 2013; 8: e65578 [PMID: 23799027 DOI: 10.1371/journal. pone.0065578]
-
(2013)
PLoS One
, vol.e65578
, pp. 8
-
-
Lai, C.H.1
Huang, S.F.2
Liao, C.T.3
Chen, I.H.4
Wang, H.M.5
Hsieh, L.L.6
-
32
-
-
0035882029
-
High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas
-
[PMID: 11507041]
-
Liu VW, Shi HH, Cheung AN, Chiu PM, Leung TW, Nagley P, Wong LC, Ngan HY. High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas. Cancer Res 2001; 61: 5998-6001 [PMID: 11507041]
-
(2001)
Cancer Res
, vol.61
, pp. 5998-6001
-
-
Liu, V.W.1
Shi, H.H.2
Cheung, A.N.3
Chiu, P.M.4
Leung, T.W.5
Nagley, P.6
Wong, L.C.7
Ngan, H.Y.8
-
33
-
-
0035866352
-
Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations
-
[PMID: 11245424]
-
Jones JB, Song JJ, Hempen PM, Parmigiani G, Hruban RH, Kern SE. Detection of mitochondrial DNA mutations in pancreatic cancer offers a "mass"-ive advantage over detection of nuclear DNA mutations. Cancer Res 2001; 61: 1299-1304 [PMID: 11245424]
-
(2001)
Cancer Res
, vol.61
, pp. 1299-1304
-
-
Jones, J.B.1
Song, J.J.2
Hempen, P.M.3
Parmigiani, G.4
Hruban, R.H.5
Kern, S.E.6
-
34
-
-
36849054642
-
Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomas
-
[PMID: 17916247 DOI: 10.1186/1472-6823-7-8]
-
Costa-Guda J, Tokura T, Roth SI, Arnold A. Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomas. BMC Endocr Disord 2007; 7: 8 [PMID: 17916247 DOI: 10.1186/1472-6823-7-8]
-
(2007)
BMC Endocr Disord
, vol.7
, pp. 8
-
-
Costa-Guda, J.1
Tokura, T.2
Roth, S.I.3
Arnold, A.4
-
35
-
-
0036836501
-
Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas
-
[PMID: 12353267 DOI: 10.1002/gcc.10118]
-
Nagy A, Wilhelm M, Sükösd F, Ljungberg B, Kovacs G. Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas. Genes Chromosomes Cancer 2002; 35: 256-260 [PMID: 12353267 DOI: 10.1002/gcc.10118]
-
(2002)
Genes Chromosomes Cancer
, vol.35
, pp. 256-260
-
-
Nagy, A.1
Wilhelm, M.2
Sükösd, F.3
Ljungberg, B.4
Kovacs, G.5
-
36
-
-
0037314430
-
Mutations of mtDNA in renal cell tumours arising in end-stage renal disease
-
[PMID: 12533837 DOI: 10.1002/path.1273]
-
Nagy A, Wilhelm M, Kovacs G. Mutations of mtDNA in renal cell tumours arising in end-stage renal disease. J Pathol 2003; 199: 237-242 [PMID: 12533837 DOI: 10.1002/path.1273]
-
(2003)
J Pathol
, vol.199
, pp. 237-242
-
-
Nagy, A.1
Wilhelm, M.2
Kovacs, G.3
-
37
-
-
31444443859
-
Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism
-
[PMID: 16404428 DOI: 10.1038/
-
Meierhofer D, Mayr JA, Fink K, Schmeller N, Kofler B, Sperl W. Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism. Br J Cancer 2006; 94: 268-274 [PMID: 16404428 DOI: 10.1038/
-
(2006)
Br J Cancer
, vol.94
, pp. 268-274
-
-
Meierhofer, D.1
Mayr, J.A.2
Fink, K.3
Schmeller, N.4
Kofler, B.5
Sperl, W.6
-
38
-
-
41149143265
-
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma
-
[PMID: 18156159 DOI: 10.1093/ hmg/ddm371]
-
Gasparre G, Hervouet E, de Laplanche E, Demont J, Pennisi LF, Colombel M, Mège-Lechevallier F, Scoazec JY, Bonora E, Smeets R, Smeitink J, Lazar V, Lespinasse J, Giraud S, Godinot C, Romeo G, Simonnet H. Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Hum Mol Genet 2008; 17: 986-995 [PMID: 18156159 DOI: 10.1093/ hmg/ddm371]
-
(2008)
Hum Mol Genet
, vol.17
, pp. 986-995
-
-
Gasparre, G.1
Hervouet, E.2
de Laplanche, E.3
Demont, J.4
Pennisi, L.F.5
Colombel, M.6
Mège-Lechevallier, F.7
Scoazec, J.Y.8
Bonora, E.9
Smeets, R.10
Smeitink, J.11
Lazar, V.12
Lespinasse, J.13
Giraud, S.14
Godinot, C.15
Romeo, G.16
Simonnet, H.17
-
39
-
-
0030925951
-
Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis
-
[PMID: 9194590 DOI: 10.1002/elps.1150180504]
-
Alonso A, Martin P, Albarran C, Aquilera B, Garcia O, Guzman A, Oliva H, Sancho M. Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis. Electrophoresis 1997; 18: 682-685 [PMID: 9194590 DOI: 10.1002/elps.1150180504]
-
(1997)
Electrophoresis
, vol.18
, pp. 682-685
-
-
Alonso, A.1
Martin, P.2
Albarran, C.3
Aquilera, B.4
Garcia, O.5
Guzman, A.6
Oliva, H.7
Sancho, M.8
-
40
-
-
0033083094
-
Mutations in mitochondrial control region DNA in gastric tumours of Japanese patients
-
[PMID: 10448277 DOI: 10.1016/S0959-8049(98)00360-8]
-
Tamura G, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Sakata K, Endoh Y, Motoyama T. Mutations in mitochondrial control region DNA in gastric tumours of Japanese patients. Eur J Cancer 1999; 35: 316-319 [PMID: 10448277 DOI: 10.1016/S0959-8049(98)00360-8]
-
(1999)
Eur J Cancer
, vol.35
, pp. 316-319
-
-
Tamura, G.1
Nishizuka, S.2
Maesawa, C.3
Suzuki, Y.4
Iwaya, T.5
Sakata, K.6
Endoh, Y.7
Motoyama, T.8
-
41
-
-
0141718471
-
Variations of mitochondrial D-loop region plus downstream gene 1 2S rRNA-tRNA(phe) and gastric carcinomas
-
[PMID: 12970877]
-
Han CB, Li F, Zhao YJ, Ma JM, Wu DY, Zhang YK, Xin Y. Variations of mitochondrial D-loop region plus downstream gene 1 2S rRNA-tRNA(phe) and gastric carcinomas. World J Gastroenterol 2003; 9: 1925-1929 [PMID: 12970877]
-
(2003)
World J Gastroenterol
, vol.9
, pp. 1925-1929
-
-
Han, C.B.1
Li, F.2
Zhao, Y.J.3
Ma, J.M.4
Wu, D.Y.5
Zhang, Y.K.6
Xin, Y.7
-
42
-
-
33644808576
-
Somatic mutations of mitochondrial DNA in digestive tract cancers
-
[PMID: 16246185 DOI: 10.1111/j.1440-1746.2005.04015.x]
-
Kose K, Hiyama T, Tanaka S, Yoshihara M, Yasui W, Chayama K. Somatic mutations of mitochondrial DNA in digestive tract cancers. J Gastroenterol Hepatol 2005; 20: 1679-1684 [PMID: 16246185 DOI: 10.1111/j.1440-1746.2005.04015.x]
-
(2005)
J Gastroenterol Hepatol
, vol.20
, pp. 1679-1684
-
-
Kose, K.1
Hiyama, T.2
Tanaka, S.3
Yoshihara, M.4
Yasui, W.5
Chayama, K.6
-
43
-
-
22144472961
-
Mutation in D-loop region of mitochondrial DNA in gastric cancer and its significance
-
[PMID: 15929189]
-
Zhao YB, Yang HY, Zhang XW, Chen GY. Mutation in D-loop region of mitochondrial DNA in gastric cancer and its significance. World J Gastroenterol 2005; 11: 3304-3306 [PMID: 15929189]
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3304-3306
-
-
Zhao, Y.B.1
Yang, H.Y.2
Zhang, X.W.3
Chen, G.Y.4
-
44
-
-
0028095263
-
mtDNA and the origin of Caucasians: Identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region
-
[PMID: 7942855]
-
Torroni A, Lott MT, Cabell MF, Chen YS, Lavergne L, Wallace DC. mtDNA and the origin of Caucasians: identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region. Am J Hum Genet 1994; 55: 760-776 [PMID: 7942855]
-
(1994)
Am J Hum Genet
, vol.55
, pp. 760-776
-
-
Torroni, A.1
Lott, M.T.2
Cabell, M.F.3
Chen, Y.S.4
Lavergne, L.5
Wallace, D.C.6
-
45
-
-
70350519645
-
Heteroplasmy of mitochondrial D310 mononucleotide repeat region in the blood of patients with Alzheimer's disease
-
[PMID: 19584455 DOI: 10.3233/JAD-2009-1156]
-
Wang PN, Lee HC, Wang CH, Ping YH, Liu TY, Chi CW, Lin KN, Liu HC. Heteroplasmy of mitochondrial D310 mononucleotide repeat region in the blood of patients with Alzheimer's disease. J Alzheimers Dis 2009; 18: 345-353 [PMID: 19584455 DOI: 10.3233/JAD-2009-1156]
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 345-353
-
-
Wang, P.N.1
Lee, H.C.2
Wang, C.H.3
Ping, Y.H.4
Liu, T.Y.5
Chi, C.W.6
Lin, K.N.7
Liu, H.C.8
-
46
-
-
16644383274
-
Less DeltamtDNA4977 than normal in various types of tumors suggests that cancer cells are essentially free of this mutation
-
[PMID: 15614730]
-
Dani MA, Dani SU, Lima SP, Martinez A, Rossi BM, Soares F, Zago MA, Simpson AJ. Less DeltamtDNA4977 than normal in various types of tumors suggests that cancer cells are essentially free of this mutation. Genet Mol Res 2004; 3: 395-409 [PMID: 15614730]
-
(2004)
Genet Mol Res
, vol.3
, pp. 395-409
-
-
Dani, M.A.1
Dani, S.U.2
Lima, S.P.3
Martinez, A.4
Rossi, B.M.5
Soares, F.6
Zago, M.A.7
Simpson, A.J.8
-
47
-
-
33745669304
-
Delta mtDNA4977 is more common in non-tumoral cells from gastric cancer sample
-
[PMID: 16824932 DOI: 10.1016/ j.arcmed.2006.02.005]
-
Kamalidehghan B, Houshmand M, Ismail P, Panahi MS, Akbari MH. Delta mtDNA4977 is more common in non-tumoral cells from gastric cancer sample. Arch Med Res 2006; 37: 730-735 [PMID: 16824932 DOI: 10.1016/ j.arcmed.2006.02.005]
-
(2006)
Arch Med Res
, vol.37
, pp. 730-735
-
-
Kamalidehghan, B.1
Houshmand, M.2
Ismail, P.3
Panahi, M.S.4
Akbari, M.H.5
-
48
-
-
0028871590
-
Somatic mitochondrial mutation in gastric cancer
-
[PMID: 7573355]
-
Burgart LJ, Zheng J, Shu Q, Strickler JG, Shibata D. Somatic mitochondrial mutation in gastric cancer. Am J Pathol 1995; 147: 1105-1111 [PMID: 7573355]
-
(1995)
Am J Pathol
, vol.147
, pp. 1105-1111
-
-
Burgart, L.J.1
Zheng, J.2
Shu, Q.3
Strickler, J.G.4
Shibata, D.5
-
49
-
-
1542345767
-
Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma
-
[PMID: 15013701 DOI: 10.1016/ j.mrfmmm.2003.12.011]
-
Lee HC, Li SH, Lin JC, Wu CC, Yeh DC, Wei YH. Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma. Mutat Res 2004; 547: 71-78 [PMID: 15013701 DOI: 10.1016/ j.mrfmmm.2003.12.011]
-
(2004)
Mutat Res
, vol.547
, pp. 71-78
-
-
Lee, H.C.1
Li, S.H.2
Lin, J.C.3
Wu, C.C.4
Yeh, D.C.5
Wei, Y.H.6
-
50
-
-
0027230737
-
A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies
-
[PMID: 8513327 DOI: 10.1038/ng0593-67]
-
Brockington M, Sweeney MG, Hammans SR, Morgan- Hughes JA, Harding AE. A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies. Nat Genet 1993; 4: 67-71 [PMID: 8513327 DOI: 10.1038/ng0593-67]
-
(1993)
Nat Genet
, vol.4
, pp. 67-71
-
-
Brockington, M.1
Sweeney, M.G.2
Hammans, S.R.3
Morgan-Hughes, J.A.4
Harding, A.E.5
-
51
-
-
0028061412
-
Ageing-associated tandem duplications in the D-loop of mitochondrial DNA of human muscle
-
[PMID: 7957906 DOI: 10.1016/0014-5793(94)01063-3]
-
Lee HC, Pang CY, Hsu HS, Wei YH. Ageing-associated tandem duplications in the D-loop of mitochondrial DNA of human muscle. FEBS Lett 1994; 354: 79-83 [PMID: 7957906 DOI: 10.1016/0014-5793(94)01063-3]
-
(1994)
FEBS Lett
, vol.354
, pp. 79-83
-
-
Lee, H.C.1
Pang, C.Y.2
Hsu, H.S.3
Wei, Y.H.4
-
52
-
-
0028948888
-
High levels of mitochondrial DNA with an unstable 260-bp duplication in a patient with a mitochondrial myopathy
-
[PMID: 7723967 DOI: 10.1212/WNL.45.4.762]
-
Manfredi G, Servidei S, Bonilla E, Shanske S, Schon EA, DiMauro S, Moraes CT. High levels of mitochondrial DNA with an unstable 260-bp duplication in a patient with a mitochondrial myopathy. Neurology 1995; 45: 762-768 [PMID: 7723967 DOI: 10.1212/WNL.45.4.762]
-
(1995)
Neurology
, vol.45
, pp. 762-768
-
-
Manfredi, G.1
Servidei, S.2
Bonilla, E.3
Shanske, S.4
Schon, E.A.5
Dimauro, S.6
Moraes, C.T.7
-
54
-
-
23944480315
-
Tumor-specific changes in mtDNA content in human cancer
-
[PMID: 15856456 DOI: 10.1002/ijc.21110]
-
Mambo E, Chatterjee A, Xing M, Tallini G, Haugen BR, Yeung SC, Sukumar S, Sidransky D. Tumor-specific changes in mtDNA content in human cancer. Int J Cancer 2005; 116: 920-924 [PMID: 15856456 DOI: 10.1002/ijc.21110]
-
(2005)
Int J Cancer
, vol.116
, pp. 920-924
-
-
Mambo, E.1
Chatterjee, A.2
Xing, M.3
Tallini, G.4
Haugen, B.R.5
Yeung, S.C.6
Sukumar, S.7
Sidransky, D.8
-
55
-
-
33646595697
-
Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer
-
[PMID: 16568452 DOI: 10.1002/ gcc.20326]
-
Tseng LM, Yin PH, Chi CW, Hsu CY, Wu CW, Lee LM, Wei YH, Lee HC. Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer. Genes Chromosomes Cancer 2006; 45: 629-638 [PMID: 16568452 DOI: 10.1002/ gcc.20326]
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 629-638
-
-
Tseng, L.M.1
Yin, P.H.2
Chi, C.W.3
Hsu, C.Y.4
Wu, C.W.5
Lee, L.M.6
Wei, Y.H.7
Lee, H.C.8
-
56
-
-
0032565577
-
Mutagenicity and repair of oxidative DNA damage: Insights from studies using defined lesions
-
[PMID: 9685598 DOI: 10.1016/S0027-5107(98)00066-9]
-
Wang D, Kreutzer DA, Essigmann JM. Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions. Mutat Res 1998; 400: 99-115 [PMID: 9685598 DOI: 10.1016/S0027-5107(98)00066-9]
-
(1998)
Mutat Res
, vol.400
, pp. 99-115
-
-
Wang, D.1
Kreutzer, D.A.2
Essigmann, J.M.3
-
57
-
-
0036570012
-
Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells
-
[PMID: 11978482 DOI: 10.1016/S0891-5849(02)00787-6]
-
Bohr VA. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 2002; 32: 804-812 [PMID: 11978482 DOI: 10.1016/S0891-5849(02)00787-6]
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 804-812
-
-
Bohr, V.A.1
-
58
-
-
0242331221
-
Mechanisms of human DNA repair: An update
-
[PMID: 14599765 DOI: 10.1016/S0300-483X(03)00287-7]
-
Christmann M, Tomicic MT, Roos WP, Kaina B. Mechanisms of human DNA repair: an update. Toxicology 2003; 193: 3-34 [PMID: 14599765 DOI: 10.1016/S0300-483X(03)00287-7]
-
(2003)
Toxicology
, vol.193
, pp. 3-34
-
-
Christmann, M.1
Tomicic, M.T.2
Roos, W.P.3
Kaina, B.4
-
59
-
-
2942523593
-
Endogenous DNA damage in humans: A review of quantitative data
-
[PMID: 15123782 DOI: 10.1093/mutage/geh025]
-
De Bont R, van Larebeke N. Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis 2004; 19: 169-185 [PMID: 15123782 DOI: 10.1093/mutage/geh025]
-
(2004)
Mutagenesis
, vol.19
, pp. 169-185
-
-
de Bont, R.1
van Larebeke, N.2
-
60
-
-
33846011884
-
Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase
-
[PMID: 17005553 DOI: 10.1074/jbc.M607965200]
-
Hanes JW, Thal DM, Johnson KA. Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase. J Biol Chem 2006; 281: 36241-36248 [PMID: 17005553 DOI: 10.1074/jbc.M607965200]
-
(2006)
J Biol Chem
, vol.281
, pp. 36241-36248
-
-
Hanes, J.W.1
Thal, D.M.2
Johnson, K.A.3
-
61
-
-
70349515574
-
Is there more to aging than mitochondrial DNA and reactive oxygen species?
-
[PMID: 19796285 DOI: 10.1111/j.1742-4658.2009.07269.x]
-
Alexeyev MF. Is there more to aging than mitochondrial DNA and reactive oxygen species? FEBS J 2009; 276: 5768-5787 [PMID: 19796285 DOI: 10.1111/j.1742-4658.2009.07269.x]
-
(2009)
FEBS J
, vol.276
, pp. 5768-5787
-
-
Alexeyev, M.F.1
-
62
-
-
4444339833
-
Oxidative DNA damage and disease: Induction, repair and significance
-
[PMID: 15341901 DOI: 10.1016/ j.mrrev.2003.11.001]
-
Evans MD, Dizdaroglu M, Cooke MS. Oxidative DNA damage and disease: induction, repair and significance. Mutat Res 2004; 567: 1-61 [PMID: 15341901 DOI: 10.1016/ j.mrrev.2003.11.001]
-
(2004)
Mutat Res
, vol.567
, pp. 1-61
-
-
Evans, M.D.1
Dizdaroglu, M.2
Cooke, M.S.3
-
64
-
-
0033565994
-
Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: Measurement, mechanism and the effects of nutrition
-
[PMID: 10415430 DOI: 10.1016/S1383-5742(99)00009-5]
-
Halliwell B. Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: measurement, mechanism and the effects of nutrition. Mutat Res 1999; 443: 37-52 [PMID: 10415430 DOI: 10.1016/S1383-5742(99)00009-5]
-
(1999)
Mutat Res
, vol.443
, pp. 37-52
-
-
Halliwell, B.1
-
65
-
-
34248174044
-
DNA repair pathways and mitochondrial DNA mutations in gastrointestinal carcinogenesis
-
[PMID: 17397816 DOI: 10.1016/j.cca.2007.02.020]
-
Basso D, Navaglia F, Fogar P, Zambon CF, Greco E, Schiavon S, Fasolo M, Stranges A, Falda A, Padoan A, Fadi E, Pedrazzoli S, Plebani M. DNA repair pathways and mitochondrial DNA mutations in gastrointestinal carcinogenesis. Clin Chim Acta 2007; 381: 50-55 [PMID: 17397816 DOI: 10.1016/j.cca.2007.02.020]
-
(2007)
Clin Chim Acta
, vol.381
, pp. 50-55
-
-
Basso, D.1
Navaglia, F.2
Fogar, P.3
Zambon, C.F.4
Greco, E.5
Schiavon, S.6
Fasolo, M.7
Stranges, A.8
Falda, A.9
Padoan, A.10
Fadi, E.11
Pedrazzoli, S.12
Plebani, M.13
-
66
-
-
0037452679
-
Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations
-
[PMID: 12578990 DOI: 10.1073/pnas.0437910100]
-
Mambo E, Gao X, Cohen Y, Guo Z, Talalay P, Sidransky D. Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations. Proc Natl Acad Sci USA 2003; 100: 1838-1843 [PMID: 12578990 DOI: 10.1073/pnas.0437910100]
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1838-1843
-
-
Mambo, E.1
Gao, X.2
Cohen, Y.3
Guo, Z.4
Talalay, P.5
Sidransky, D.6
-
67
-
-
0036639779
-
The mitochondrial DNA polymerase as a target of oxidative damage
-
[PMID: 12087165 DOI: 10.1093/nar/gkf392]
-
Graziewicz MA, Day BJ, Copeland WC. The mitochondrial DNA polymerase as a target of oxidative damage. Nucleic Acids Res 2002; 30: 2817-2824 [PMID: 12087165 DOI: 10.1093/nar/gkf392]
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2817-2824
-
-
Graziewicz, M.A.1
Day, B.J.2
Copeland, W.C.3
-
68
-
-
70349606857
-
Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis
-
[PMID: 19629138 DOI: 10.1038/jhg.2009.71]
-
Singh KK, Ayyasamy V, Owens KM, Koul MS, Vujcic M. Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis. J Hum Genet 2009; 54: 516-524 [PMID: 19629138 DOI: 10.1038/jhg.2009.71]
-
(2009)
J Hum Genet
, vol.54
, pp. 516-524
-
-
Singh, K.K.1
Ayyasamy, V.2
Owens, K.M.3
Koul, M.S.4
Vujcic, M.5
-
69
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
[PMID: 15164064 DOI: 10.1038/nature02517]
-
Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, Bruder CE, Bohlooly Y M, Gidlöf S, Oldfors A, Wibom R, Törnell J, Jacobs HT, Larsson NG. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 2004; 429: 417-423 [PMID: 15164064 DOI: 10.1038/nature02517]
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlöf, S.8
Oldfors, A.9
Wibom, R.10
Törnell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
70
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
[PMID: 16020738]
-
Kujoth GC, Hiona A, Pugh TD, Someya S, Panzer K, Wohlgemuth SE, Hofer T, Seo AY, Sullivan R, Jobling WA, Morrow JD, Van Remmen H, Sedivy JM, Yamasoba T, Tanokura M, Weindruch R, Leeuwenburgh C, Prolla TA. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 2005; 309: 481-484 [PMID: 16020738]
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
Morrow, J.D.11
van Remmen, H.12
Sedivy, J.M.13
Yamasoba, T.14
Tanokura, M.15
Weindruch, R.16
Leeuwenburgh, C.17
Prolla, T.A.18
-
71
-
-
65649154690
-
Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in gastric cells
-
[PMID: 19383819 DOI: 10.1158/1078-0432.CCR-08-2686]
-
Machado AM, Figueiredo C, Touati E, Máximo V, Sousa S, Michel V, Carneiro F, Nielsen FC, Seruca R, Rasmussen LJ. Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in gastric cells. Clin Cancer Res 2009; 15: 2995-3002 [PMID: 19383819 DOI: 10.1158/1078-0432.CCR-08-2686]
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2995-3002
-
-
Machado, A.M.1
Figueiredo, C.2
Touati, E.3
Máximo, V.4
Sousa, S.5
Michel, V.6
Carneiro, F.7
Nielsen, F.C.8
Seruca, R.9
Rasmussen, L.J.10
-
72
-
-
77953718630
-
Helicobacter pylori infection generates genetic instability in gastric cells
-
[PMID: 20122996 DOI: 10.1016/j.bbcan.2010.01.007]
-
Machado AM, Figueiredo C, Seruca R, Rasmussen LJ. Helicobacter pylori infection generates genetic instability in gastric cells. Biochim Biophys Acta 2010; 1806: 58-65 [PMID: 20122996 DOI: 10.1016/j.bbcan.2010.01.007]
-
(2010)
Biochim Biophys Acta
, vol.1806
, pp. 58-65
-
-
Machado, A.M.1
Figueiredo, C.2
Seruca, R.3
Rasmussen, L.J.4
-
73
-
-
84888138484
-
Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells
-
[PMID: 24012633 DOI: 10.1016/j.mad.2013]
-
Machado AM, Desler C, Bøggild S, Strickertsson JA, Friis- Hansen L, Figueiredo C, Seruca R, Rasmussen LJ. Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells. Mech Ageing Dev 2013; 134: 460-466 [PMID: 24012633 DOI: 10.1016/j.mad.2013]
-
(2013)
Mech Ageing Dev
, vol.134
, pp. 460-466
-
-
Machado, A.M.1
Desler, C.2
Bøggild, S.3
Strickertsson, J.A.4
Friis-Hansen, L.5
Figueiredo, C.6
Seruca, R.7
Rasmussen, L.J.8
-
74
-
-
3042699833
-
Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma
-
[PMID: 15150555 DOI: 10.1038/sj.bjc.6601838]
-
Yin PH, Lee HC, Chau GY, Wu YT, Li SH, Lui WY, Wei YH, Liu TY, Chi CW. Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma. Br J Cancer 2004; 90: 2390-2396 [PMID: 15150555 DOI: 10.1038/sj.bjc.6601838]
-
(2004)
Br J Cancer
, vol.90
, pp. 2390-2396
-
-
Yin, P.H.1
Lee, H.C.2
Chau, G.Y.3
Wu, Y.T.4
Li, S.H.5
Lui, W.Y.6
Wei, Y.H.7
Liu, T.Y.8
Chi, C.W.9
-
75
-
-
56749091977
-
Expression of beta-F1-ATPase and mitochondrial transcription factor A and the change in mitochondrial DNA content in colorectal cancer: Clinical data analysis and evidence from an in vitro study
-
[PMID: 18769884 DOI: 10.1007/s00384-008-0539-4]
-
Lin PC, Lin JK, Yang SH, Wang HS, Li AF, Chang SC. Expression of beta-F1-ATPase and mitochondrial transcription factor A and the change in mitochondrial DNA content in colorectal cancer: clinical data analysis and evidence from an in vitro study. Int J Colorectal Dis 2008; 23: 1223-1232 [PMID: 18769884 DOI: 10.1007/s00384-008-0539-4]
-
(2008)
Int J Colorectal Dis
, vol.23
, pp. 1223-1232
-
-
Lin, P.C.1
Lin, J.K.2
Yang, S.H.3
Wang, H.S.4
Li, A.F.5
Chang, S.C.6
-
76
-
-
27144488229
-
Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma
-
[PMID: 16163384 DOI: 10.1038/sj.emboj.7600819]
-
Achanta G, Sasaki R, Feng L, Carew JS, Lu W, Pelicano H, Keating MJ, Huang P. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. EMBO J 2005; 24: 3482-3492 [PMID: 16163384 DOI: 10.1038/sj.emboj.7600819]
-
(2005)
EMBO J
, vol.24
, pp. 3482-3492
-
-
Achanta, G.1
Sasaki, R.2
Feng, L.3
Carew, J.S.4
Lu, W.5
Pelicano, H.6
Keating, M.J.7
Huang, P.8
-
77
-
-
74049094817
-
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
-
[PMID: 20129246 DOI: 10.1016/j.ccr.2009.11.023]
-
Kim HS, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JD, van der Meer R, Nguyen P, Savage J, Owens KM, Vassilopoulos A, Ozden O, Park SH, Singh KK, Abdulkadir SA, Spitz DR, Deng CX, Gius D. SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell 2010; 17: 41-52 [PMID: 20129246 DOI: 10.1016/j.ccr.2009.11.023]
-
(2010)
Cancer Cell
, vol.17
, pp. 41-52
-
-
Kim, H.S.1
Patel, K.2
Muldoon-Jacobs, K.3
Bisht, K.S.4
Aykin-Burns, N.5
Pennington, J.D.6
van der Meer, R.7
Nguyen, P.8
Savage, J.9
Owens, K.M.10
Vassilopoulos, A.11
Ozden, O.12
Park, S.H.13
Singh, K.K.14
Abdulkadir, S.A.15
Spitz, D.R.16
Deng, C.X.17
Gius, D.18
-
78
-
-
84897108383
-
SIRT3 Expression as a Biomarker for Better Prognosis in Gastric Cancer
-
[PMID: 24322174 DOI: 10.1007/ s00268-013-2359-0]
-
Huang KH, Hsu CC, Fang WL, Chi CW, Sung MT, Kao HL, Li AF, Yin PH, Yang MH, Lee HC. SIRT3 Expression as a Biomarker for Better Prognosis in Gastric Cancer. World J Surg 2014; 38: 910-917 [PMID: 24322174 DOI: 10.1007/ s00268-013-2359-0]
-
(2014)
World J Surg
, vol.38
, pp. 910-917
-
-
Huang, K.H.1
Hsu, C.C.2
Fang, W.L.3
Chi, C.W.4
Sung, M.T.5
Kao, H.L.6
Li, A.F.7
Yin, P.H.8
Yang, M.H.9
Lee, H.C.10
-
79
-
-
84890858374
-
Aberrant expression of SIRT3 is conversely correlated with the progression and prognosis of human gastric cancer
-
[PMID: 24287180 DOI: 10.1016/ j.bbrc.2013.11.068]
-
Yang B, Fu X, Shao L, Ding Y, Zeng D. Aberrant expression of SIRT3 is conversely correlated with the progression and prognosis of human gastric cancer. Biochem Biophys Res Commun 2014; 443: 156-160 [PMID: 24287180 DOI: 10.1016/ j.bbrc.2013.11.068]
-
(2014)
Biochem Biophys Res Commun
, vol.443
, pp. 156-160
-
-
Yang, B.1
Fu, X.2
Shao, L.3
Ding, Y.4
Zeng, D.5
-
80
-
-
2342551462
-
Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer
-
[PMID: 14534705]
-
Hiyama T, Tanaka S, Shima H, Kose K, Tuncel H, Ito M, Kitadai Y, Sumii M, Yoshihara M, Shimamoto F, Haruma K, Chayama K. Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer. Oncol Rep 2003; 10: 1837-1841 [PMID: 14534705]
-
(2003)
Oncol Rep
, vol.10
, pp. 1837-1841
-
-
Hiyama, T.1
Tanaka, S.2
Shima, H.3
Kose, K.4
Tuncel, H.5
Ito, M.6
Kitadai, Y.7
Sumii, M.8
Yoshihara, M.9
Shimamoto, F.10
Haruma, K.11
Chayama, K.12
-
81
-
-
0141976372
-
Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer
-
[PMID: 12851712]
-
Hiyama T, Tanaka S, Shima H, Kose K, Kitadai Y, Ito M, Sumii M, Yoshihara M, Shimamoto F, Haruma K, Chayama K. Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer. Int J Mol Med 2003; 12: 169-174 [PMID: 12851712]
-
(2003)
Int J Mol Med
, vol.12
, pp. 169-174
-
-
Hiyama, T.1
Tanaka, S.2
Shima, H.3
Kose, K.4
Kitadai, Y.5
Ito, M.6
Sumii, M.7
Yoshihara, M.8
Shimamoto, F.9
Haruma, K.10
Chayama, K.11
-
82
-
-
84867334412
-
Deficiency of the complex I of the mitochondrial respiratory chain but improved adenylate control over succinate-dependent respiration are human gastric cancer-specific phenomena
-
[PMID: 22821176 DOI: 10.1007/ s11010-012-1399-3]
-
Puurand M, Peet N, Piirsoo A, Peetsalu M, Soplepmann J, Sirotkina M, Peetsalu A, Hemminki A, Seppet E. Deficiency of the complex I of the mitochondrial respiratory chain but improved adenylate control over succinate-dependent respiration are human gastric cancer-specific phenomena. Mol Cell Biochem 2012; 370: 69-78 [PMID: 22821176 DOI: 10.1007/ s11010-012-1399-3]
-
(2012)
Mol Cell Biochem
, vol.370
, pp. 69-78
-
-
Puurand, M.1
Peet, N.2
Piirsoo, A.3
Peetsalu, M.4
Soplepmann, J.5
Sirotkina, M.6
Peetsalu, A.7
Hemminki, A.8
Seppet, E.9
-
83
-
-
84879378746
-
Decreased expression of the mitochondrial metabolic enzyme aconitase (ACO2) is associated with poor prognosis in gastric cancer
-
[PMID: 23550275 DOI: 10.1007/s12032-013-0552-5]
-
Wang P, Mai C, Wei YL, Zhao JJ, Hu YM, Zeng ZL, Yang J, Lu WH, Xu RH, Huang P. Decreased expression of the mitochondrial metabolic enzyme aconitase (ACO2) is associated with poor prognosis in gastric cancer. Med Oncol 2013; 30: 552 [PMID: 23550275 DOI: 10.1007/s12032-013-0552-5]
-
(2013)
Med Oncol
, vol.30
, pp. 552
-
-
Wang, P.1
Mai, C.2
Wei, Y.L.3
Zhao, J.J.4
Hu, Y.M.5
Zeng, Z.L.6
Yang, J.7
Lu, W.H.8
Xu, R.H.9
Huang, P.10
-
84
-
-
64549098628
-
A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis
-
[PMID: 19208652 DOI: 10.1093/hmg/ddp069]
-
Park JS, Sharma LK, Li H, Xiang R, Holstein D, Wu J, Lechleiter J, Naylor SL, Deng JJ, Lu J, Bai Y. A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis. Hum Mol Genet 2009; 18: 1578-1589 [PMID: 19208652 DOI: 10.1093/hmg/ddp069]
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1578-1589
-
-
Park, J.S.1
Sharma, L.K.2
Li, H.3
Xiang, R.4
Holstein, D.5
Wu, J.6
Lechleiter, J.7
Naylor, S.L.8
Deng, J.J.9
Lu, J.10
Bai, Y.11
-
85
-
-
0028889974
-
Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase
-
[PMID: 7823960]
-
Hofhaus G, Attardi G. Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase. Mol Cell Biol 1995; 15: 964-974 [PMID: 7823960]
-
(1995)
Mol Cell Biol
, vol.15
, pp. 964-974
-
-
Hofhaus, G.1
Attardi, G.2
-
86
-
-
0031736203
-
Somatic mutations of the mitochondrial genome in human colorectal tumours
-
[PMID: 9806551 DOI: 10.1038/3108]
-
Polyak K, Li Y, Zhu H, Lengauer C, Willson JK, Markowitz SD, Trush MA, Kinzler KW, Vogelstein B. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat Genet 1998; 20: 291-293 [PMID: 9806551 DOI: 10.1038/3108]
-
(1998)
Nat Genet
, vol.20
, pp. 291-293
-
-
Polyak, K.1
Li, Y.2
Zhu, H.3
Lengauer, C.4
Willson, J.K.5
Markowitz, S.D.6
Trush, M.A.7
Kinzler, K.W.8
Vogelstein, B.9
-
87
-
-
84860803392
-
Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced β5-integrin expression in human gastric cancer SC-M1 cells
-
[PMID: 22561002 DOI: 10.1016/j.bbagen.2012.04.016]
-
Hung WY, Huang KH, Wu CW, Chi CW, Kao HL, Li AF, Yin PH, Lee HC. Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced β5-integrin expression in human gastric cancer SC-M1 cells. Biochim Biophys Acta 2012; 1820: 1102-1110 [PMID: 22561002 DOI: 10.1016/j.bbagen.2012.04.016]
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 1102-1110
-
-
Hung, W.Y.1
Huang, K.H.2
Wu, C.W.3
Chi, C.W.4
Kao, H.L.5
Li, A.F.6
Yin, P.H.7
Lee, H.C.8
-
88
-
-
20044364344
-
mtDNA mutations increase tumorigenicity in prostate cancer
-
[PMID: 15647368 DOI: 10.1073/pnas.0408894102]
-
Petros JA, Baumann AK, Ruiz-Pesini E, Amin MB, Sun CQ, Hall J, Lim S, Issa MM, Flanders WD, Hosseini SH, Marshall FF, Wallace DC. mtDNA mutations increase tumorigenicity in prostate cancer. Proc Natl Acad Sci USA 2005; 102: 719-724 [PMID: 15647368 DOI: 10.1073/pnas.0408894102]
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 719-724
-
-
Petros, J.A.1
Baumann, A.K.2
Ruiz-Pesini, E.3
Amin, M.B.4
Sun, C.Q.5
Hall, J.6
Lim, S.7
Issa, M.M.8
Flanders, W.D.9
Hosseini, S.H.10
Marshall, F.F.11
Wallace, D.C.12
-
89
-
-
16444386967
-
Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis
-
[PMID: 15753359 DOI: 10.1158/0008-5472.CAN-04-2012]
-
Shidara Y, Yamagata K, Kanamori T, Nakano K, Kwong JQ, Manfredi G, Oda H, Ohta S. Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Res 2005; 65: 1655-1663 [PMID: 15753359 DOI: 10.1158/0008-5472.CAN-04-2012]
-
(2005)
Cancer Res
, vol.65
, pp. 1655-1663
-
-
Shidara, Y.1
Yamagata, K.2
Kanamori, T.3
Nakano, K.4
Kwong, J.Q.5
Manfredi, G.6
Oda, H.7
Ohta, S.8
-
90
-
-
33746877057
-
Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs
-
[PMID: 16892089 DOI: 10.1038/sj.onc.1209602]
-
Ohta S. Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs. Oncogene 2006; 25: 4768-4776 [PMID: 16892089 DOI: 10.1038/sj.onc.1209602]
-
(2006)
Oncogene
, vol.25
, pp. 4768-4776
-
-
Ohta, S.1
-
91
-
-
43249112094
-
ROSgenerating mitochondrial DNA mutations can regulate tumor cell metastasis
-
[PMID: 18388260 DOI: 10.1126/science.1156906]
-
Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J. ROSgenerating mitochondrial DNA mutations can regulate tumor cell metastasis. Science 2008; 320: 661-664 [PMID: 18388260 DOI: 10.1126/science.1156906]
-
(2008)
Science
, vol.320
, pp. 661-664
-
-
Ishikawa, K.1
Takenaga, K.2
Akimoto, M.3
Koshikawa, N.4
Yamaguchi, A.5
Imanishi, H.6
Nakada, K.7
Honma, Y.8
Hayashi, J.9
-
92
-
-
0035901495
-
Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion
-
[PMID: 11296224 DOI: 10.1093/emboj/20.8.1910]
-
Amuthan G, Biswas G, Zhang SY, Klein-Szanto A, Vijayasarathy C, Avadhani NG. Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion. EMBO J 2001; 20: 1910-1920 [PMID: 11296224 DOI: 10.1093/emboj/20.8.1910]
-
(2001)
EMBO J
, vol.20
, pp. 1910-1920
-
-
Amuthan, G.1
Biswas, G.2
Zhang, S.Y.3
Klein-Szanto, A.4
Vijayasarathy, C.5
Avadhani, N.G.6
-
93
-
-
0037038669
-
Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
-
[PMID: 12420221 DOI: 10.1038/ sj.onc.1205983]
-
Amuthan G, Biswas G, Ananadatheerthavarada HK, Vijayasarathy C, Shephard HM, Avadhani NG. Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene 2002; 21: 7839-7849 [PMID: 12420221 DOI: 10.1038/ sj.onc.1205983]
-
(2002)
Oncogene
, vol.21
, pp. 7839-7849
-
-
Amuthan, G.1
Biswas, G.2
Ananadatheerthavarada, H.K.3
Vijayasarathy, C.4
Shephard, H.M.5
Avadhani, N.G.6
-
94
-
-
33644870379
-
Oxidative phosphorylation dysfunction modulates expression of extracellular matrix--remodeling genes and invasion
-
[PMID: 16221732 DOI: 10.1093/car-
-
van Waveren C, Sun Y, Cheung HS, Moraes CT. Oxidative phosphorylation dysfunction modulates expression of extracellular matrix--remodeling genes and invasion. Carcinogenesis 2006; 27: 409-418 [PMID: 16221732 DOI: 10.1093/car-
-
(2006)
Carcinogenesis
, vol.27
, pp. 409-418
-
-
van Waveren, C.1
Sun, Y.2
Cheung, H.S.3
Moraes, C.T.4
-
95
-
-
23644436504
-
Mitochondria-to-nucleus stress signaling in mammalian cells: Nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis
-
[PMID: 15978749 DOI: 10.1016/j.gene.2005.03.028]
-
Biswas G, Guha M, Avadhani NG. Mitochondria-to-nucleus stress signaling in mammalian cells: nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis. Gene 2005; 354: 132-139 [PMID: 15978749 DOI: 10.1016/j.gene.2005.03.028]
-
(2005)
Gene
, vol.354
, pp. 132-139
-
-
Biswas, G.1
Guha, M.2
Avadhani, N.G.3
-
96
-
-
84890937655
-
Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma
-
[PMID: 24379611 DOI: 10.3748/wjg.v19.i47.8880]
-
Hsu CC, Lee HC, Wei YH. Mitochondrial DNA alterations and mitochondrial dysfunction in the progression of hepatocellular carcinoma. World J Gastroenterol 2013; 19: 8880-8886 [PMID: 24379611 DOI: 10.3748/wjg.v19.i47.8880]
-
(2013)
World J Gastroenterol
, vol.19
, pp. 8880-8886
-
-
Hsu, C.C.1
Lee, H.C.2
Wei, Y.H.3
-
97
-
-
1842665662
-
Mitochondrial signaling: The retrograde response
-
[PMID: 15068799 DOI: 10.1016/S1097-2765(04)00179-0]
-
Butow RA, Avadhani NG. Mitochondrial signaling: the retrograde response. Mol Cell 2004; 14: 1-15 [PMID: 15068799 DOI: 10.1016/S1097-2765(04)00179-0]
-
(2004)
Mol Cell
, vol.14
, pp. 1-15
-
-
Butow, R.A.1
Avadhani, N.G.2
-
98
-
-
33845656956
-
Mitochondrial retrograde signaling
-
[PMID: 16771627 DOI: 10.1146/ annurev.genet.40.110405]
-
Liu Z, Butow RA. Mitochondrial retrograde signaling. Annu Rev Genet 2006; 40: 159-185 [PMID: 16771627 DOI: 10.1146/ annurev.genet.40.110405]
-
(2006)
Annu Rev Genet
, vol.40
, pp. 159-185
-
-
Liu, Z.1
Butow, R.A.2
|