Human mitochondrial DNA: Roles of inherited and somatic mutations

Nature Reviews Genetics

Volumn 13, Issue 12, 2012, Pages 878-890

  Schon, Eric A ^a   Dimauro, Salvatore ^a   Hirano, Michio ^a  

^a New York Presbyterian Morgan Stanley Children's Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; FUMARATE HYDRATASE; HYPOXIA INDUCIBLE FACTOR 1; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RIBOSOME RNA; RNA 16S; SUCCINATE DEHYDROGENASE; TRANSFER RNA; UBIQUINOL CYTOCHROME C REDUCTASE; VOLTAGE DEPENDENT ANION CHANNEL 1;

AGING; CELL DEATH; CHROMOSOMAL INSTABILITY; GENE MUTATION; GENE PRODUCT; GENETIC SUSCEPTIBILITY; HUMAN; KEARNS SAYRE SYNDROME; LEBER HEREDITARY OPTIC NEUROPATHY; MELAS SYNDROME; MEMBRANE POTENTIAL; MERRF SYNDROME; NARP SYNDROME; NERVE DEGENERATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SOMATIC MUTATION;

AGING; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; GENOME, MITOCHONDRIAL; GERM-LINE MUTATION; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; MITOCHONDRIAL DISEASES; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NEOPLASMS; OXIDATIVE PHOSPHORYLATION;

EID: 84869397441     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg3275     Document Type: Review

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