Synaptic abnormalities in a Drosophila model of Alzheimer's disease

DMM Disease Models and Mechanisms

Volumn 7, Issue 3, 2014, Pages 373-385

  Mhatre, Siddhita D ^a   Satyasi, Vivek ^a   Killen, Mark ^a   Paddock, Brie E ^b   Moir, Robert D ^c   Saunders, Aleister J ^a,d   Marenda, Daniel R ^a,d  

^a DREXEL UNIVERSITY   (United States)

^b ARCADIA UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; APP; BACE; Drosophila; NMJ; Synapse

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE INHIBITOR; L 685458; UNCLASSIFIED DRUG; APP PROTEIN, HUMAN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; DROSOPHILA PROTEIN; ENZYME INHIBITOR; SECRETASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; BRAIN DISEASE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FRUIT FLY MODEL; GENETIC ANALYSIS; LARVA; LOCOMOTION; MITOCHONDRION; MOTONEURON; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPSE; SYNAPTIC ABNORMALITY; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; DROSOPHILA MELANOGASTER; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; PROTEIN TRANSPORT; TRANSGENE; TRANSGENIC ANIMAL;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ASPARTIC ACID ENDOPEPTIDASES; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENZYME INHIBITORS; HUMANS; LARVA; MITOCHONDRIA; MOTOR NEURONS; PHENOTYPE; PROTEIN TRANSPORT; SYNAPSES; TRANSGENES;

EID: 84897147375     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.012104     Document Type: Article

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