Characterization of a drosophila Alzheimer's disease model: Pharmacological rescue of cognitive defects

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Chakraborty, Ranjita ^a   Vepuri, Vidya ^a,b   Mhatre, Siddhita D ^a   Paddock, Brie E ^a   Miller, Sean ^a   Michelson, Sarah J ^a   Delvadia, Radha ^a   Desai, Arkit ^a   Vinokur, Marianna ^a   Melicharek, David J ^a   Utreja, Suruchi ^a   Khandelwal, Preeti ^a   Ansaloni, Sara ^a   Goldstein, Lee E ^c   Moir, Robert D ^d   Lee, Jeremy C ^e   Tabb, Loni P ^a   Saunders, Aleister J ^a,f   Marenda, Daniel R ^a,f  

^a DREXEL UNIVERSITY   (United States)

^b UNIVERSITY OF THE SCIENCES   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GAMMA SECRETASE INHIBITOR; L 685458; UNCLASSIFIED DRUG; CARBAMIC ACID DERIVATIVE; DIPEPTIDE; PROTEINASE INHIBITOR; SECRETASE;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BRAIN TISSUE; CELL STRAIN HEK293; CENTRAL NERVOUS SYSTEM; COGNITIVE DEFECT; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MALE; MEMORY DISORDER; MOTOR DYSFUNCTION; NEUROCHEMISTRY; NEUROPATHOLOGY; NONHUMAN; PHENOTYPE; PROTEIN AGGREGATION; SYMPTOMATOLOGY; TRANSGENICS; ANIMAL; BRAIN; COGNITION; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOTOR ACTIVITY; PATHOPHYSIOLOGY; PHYSIOLOGY; REFLEX; TIME;

DROSOPHILA MELANOGASTER;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CARBAMATES; COGNITION; DIPEPTIDES; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DRUG EVALUATION, PRECLINICAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MOTOR ACTIVITY; PHENOTYPE; PROTEASE INHIBITORS; REFLEX; TIME FACTORS;

EID: 79958171117     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020799     Document Type: Article

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