Glutamate receptor anchoring proteins and the molecular organization of excitatory synapses

Annals of the New York Academy of Sciences

Volumn 868, Issue , 1999, Pages 483-493

  Sheng, Morgan ^a   Pak, Daniel T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; GLUTAMATE RECEPTOR; IONOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN; RECEPTOR SUBUNIT;

CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; CYTOPLASM; DENSITY; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SYNAPSE;

EID: 0033047398     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb11317.x     Document Type: Conference Paper

References (60)

1. Sheng, M. & E. Kim. 1996. Ion channel associated proteins. Curr. Opin. Neurobiol. 6: 602-608.
2. Kornau, H.-C., L.T. Schenker, M.B. Kennedy & P.H. Seeburg. 1995. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269: 1737-1740.
3. Niethammer, M., E. Kim & M. Sheng. 1996. Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases. J. Neurosci. 16: 2157-2163.
4. + channels by interaction with a family of membrane-associated guanylate kinases. Nature 378: 85-88.
5. Sheng, M. 1996. PDZs and receptor/channel clustering: Rounding up the latest suspects. Neuron 17: 575-578.
6. Doyle, D.A., A. Lee, J. Lewis, E. Kim, M. Sheng & R. MacKinnon. 1996. Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ. Cell 85: 1067-1076.
7. Cho, K.-O., C.A. Hunt & M.B. Kennedy. 1992. The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein. Neuron 9: 929-942.
8. Kistner, U., B.M. Wenzel, R.W. Veh, C. Cases-Langhoff, A.M. Garner, U. Appeltauer, B. Voss, E.D. Gundelfinger & C.C. Garner. 1993. SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A. J. Biol. Chem. 268: 4580-4583.
9. Wyszynski, M., J. Lin, A. Rao, E. Nigh, A.H. Beggs, A.M. Craig & M. Sheng. 1997. Competitive binding of α-actinin and calmodulin to the NMDA receptor. Nature 385: 439-442.
10. Rao, A., E. Kim, M. Sheng & A.M. Craig. 1998. Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture. J. Neurosci. 18: 1217-1229.
11. Hunt, C.A., L.J. Schenker & M.B. Kennedy. 1996. PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses. J. Neurosci. 16: 1380-1388.
12. Niethammer, M., J.G. Valtschanoff, T.M. Kapoor, D.W. Allison, R.J. Weinberg, A.M. Craig & M. Sheng. 1998. CRlPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90. Neuron 20: 693-707.
13. Rao, A. & A.M. Craig. 1997. Activity regulates the synaptic localization of the NMDA receptor in hippocampal neurons. Neuron 19: 801-812.
14. Muller, B.M., U. Kistner, S. Kindler, W.J. Chung, S. Kuhlendahl, L.F. Lau, R.W. Veh, R.L. Huganir, E.D. Gundelfinger & C.C. Garner. 1996. SAP102, a novel postsynaptic protein that interacts with the cytoplasmic tail of the NMDA receptor subunit NR2B. Neuron 17: 255-265.
15. Muller, B.M., U. Kistner, R.W. Veh, C. Cases-Langhoff, B. Becker, E.D. Gundelfinger & C.C. Garner. 1995. Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein. J. Neurosci. 15: 2354-2366.
16. Brenman, J.E., K.S. Christopherson, S.E. Craven, A.W. McGee & D.S. Bredt. 1996. Cloning and characterization of postsynaptic density 93, a nitric oxide synthase interacting protein. J. Neurosci. 16: 7407-7415.
17. + channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases. Neuropharmacology. 35: 993-1000.
18. Hsueh, Y.-P., E. Kim & M. Sheng. 1997. Disulfide-linked head-to-head multimerization in the mechanism of ion channel clustering by PSD-95. Neuron 18: 803-814.
19. Phillips, W.D., C. Kopta, P. Blount, P.D. Gardner, J.H. Steinbach & J.P. Merlie. 1991. ACh receptor-rich membrane domains organized in fibroblasts by recombinant 43-kildalton protein. Science 251: 568-570.
20. Kim, E., K.-O. Cho, A. Rothschild & M. Sheng. 1996. Heteromultimerization and NMDA receptor-clustering activity of chapsyn-110, a member of the PSD-95 family of proteins. Neuron 17: 103-113.
21. Topinka, J.R. & D.S. Bredt. 1998. N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4. Neuron 20: 125-134.
22. Woods, D.F. & P.J. Bryant. 1991. The discs-large tumor suppressor gene of drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell 66: 451-464.
23. + channels in vivo. J. Neurosci. 17: 152-159.
24. Zrro, K., R.D. Fetter, C.S. Goodman & E.Y. Isacoff. 1997. Synaptic clustering of fasciclin II and shaker: Essential targeting sequences and role of dlg. Neuron 19: 1007-1016.
25. Lahey, T., M. Gorczyca, X.-X. Jia & V. Budnik. 1994. The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure. Neuron 13: 823-835.
26. Brenman, J.E., D.S. Chao, S.H. Gee, A.W. McGee, S.E. Craven, D.R. Santillano, Z. Wu, F. Huang, H. Xia, M.F. Peters, S.C. Froehner & D.S. Bredt. 1996. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and αI-syntrophin mediated by PDZ domains. Cell 84: 757-767.
27. Schuman, E.M. & D.V. Madison. 1994. Nitric oxide and synaptic function. Annu. Rev. Neurosci. 17: 153-183.
28. Jaffrey, S.R. & S.H. Snyder. 1995. Nitric oxide: A neural messenger. Annu. Rev. Cell Dev. Biol. 11: 417-440.
29. Kim, J.H., D. Liao, L.-F. Lau & R.L. Huganir. 1998. SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron 20: 683-691.
30. Chen, H.J., M. Rojas-Sota, A. Oguni & M.B. Kennedy. 1998. A synaptic RasGTPase activating protein inhibited by CaM Kinase II. Neuron 20: 895-904.
31. Matsumine, A., A. Ogai, T. Senda, N. Okumura, K. Satoh, G.-H. Baeg, T. Kawahara, S. Kobayashi, M. Okada, K. Toyoshima & T. Akiyama. 1996. Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein. Science 272: 1020-1023.
32. Willert, K. & R. Nusse. 1998. β-catenin: A key mediator of Wnt signaling. Curr. Opin. Genet. Dev. 8: 95-102.
33. Pawson, T. 1995. Protein modules and signalling networks. Nature 373: 573-580.
34. Kim, E., S. Naisbitt, Y.-P. Hsueh, A. Rao, A. Rothschild, A.M. Craig & M. Sheng. 1997. GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules. J. Cell Biol. 136: 669-678.
35. Naisbitt, S., E. Kim, R.J. Weinberg, A. Rao, F.-C. Yang, A.M. Craig & M. Sheng. 1997. Characterization of guanylate kinase-associated protein, a postsynaptic density protein at excitatory synapses that interacts directly with posysynaptic density-95/synapse-associated protein 90. J. Neurosci. 17: 5687-5696.
36. Takeuchi, M., Y. Hata, K. Hirao, A. Toyoda, M. Irie & Y. Takai. 1997. SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. J. Biol. Chem. 272: 11943-11951.
37. Kistner, U., C.C. Garner & M. Linial. 1995. Nucleotide binding by the synapse associated protein SAP90. FEBS Lett. 359: 159-163.
38. Sprengel, R., B. Suchanek, C. Amico, R. Brusa, N. Burnasheve, A. Rozov, O. Hvalby, V. Jensen, O. Paulsen, P. Andersen, J.J. Kim, R.F. Thompson, W. Sun, L.C. Webster, S.G.N. Grant, J. Eilers, A. Konnerth, J. Li, J.O. McNamara & P.H. Seeburg. 1998. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 92: 279-289.
39. + channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation. Neuron 17: 759-767.
40. Horio, Y., H. Hibino, A. Inanobe, M. Yamada, M. Ishii, Y. Tada, E. Satoh, Y. Hata, Y. Takai & Y. Kurachi. 1997. Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90. J. Biol. Chem. 272: 12885-12888.
41. Kim, E., S.J. DeMarco, S.M. Marfatia, A.H. Chishti, M. Sheng & E.E. Strehler. 1998. Plasma membrane Ca2+ ATPase isoform 4b binds to membrane-associated guanylate kinase (MAGUK) proteins via their PDZ (PSD-95/Dlg/ZO-1) domains. J. Biol. Chem. 273: 1591-1595.
42. Thomas, U., E. Kim, S. Kuhlendahl, Y. Ho Koh, E.D. Gundelfinger, M. Sheng, C.C. Garner & V. Budnik. 1997. Synaptic clustering of the cell adhesion molecule fasciclin II by discs-large and its role in the regulation of presynaptic structure. Neuron 19: 787-799.
43. Irie, M., Y. Hata, M. Takeuchi, K. Ichtchenko, A. Toyoda, K. Hirao, Y. Takai, T.W. Rosahl & T.C. Südhof. 1997. Binding of neuroligins to PSD-95. Science 277: 1511-1515.
44. Lue, R.A., E. Brandin, E.P. Chan & D. Branton. 1996. Two independent domains of hDlg are sufficient for subcellular targeting: The PDZ1-2 conformational unit and an alternatively spliced domain. J. Cell Biol. 135: 1125-1137.
45. Marfatia, S.M., J.H.M. Cabral, L. Lin, C. Hough, P.J. Bryant, L. Stolz & A.H. Chishti. 1996. Modular organization of the PDZ domains in the human discs-large protein suggests a mechanism for coupling PDZ domain-binding proteins to ATP and the membrane cytoskeleton. J. Cell Biol. 135: 753-766.
46. Kaech, S., M. Fischer, T. Doll & A. Matus. 1997. Isoform specificity in the relationship of actin to dendritic spines. J. Neurosci. 17: 9565-9572.
47. Wyszynski, M., V. Kharazia, R. Shanghvi, A. Rao, A.H. Beggs, A.M. Craig, R. Weinberg & M. Sheng. 1998. Differential regional expression and ultrastructural localization of α-actinin-2, a putative NMDA receptor-anchoring protein, in rat brain. J. Neurosci. 18: 1383-1392.
48. Ehlers, M.D., S. Zhang, J.P. Bernhardt & R.L. Huganir. 1996. Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell 84: 745-755.
49. Rosenmund, C. & G.L. Westbrook. 1993. Calcium-induced actin depolymerization reduces NMDA channel activity. Neuron 10: 805-814.
50. Tingley, W.G., K.W. Roche, A.K. Thompson & R.L. Huganir. 1993. Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain. Nature 364: 70-73.
51. Ehlers, M.D., W.G. Tingley & R.L. Huganir. 1995. Regulated subcellular distribution of the NR1 subunit of the NMDA receptor. Science 269: 1734-1737.
52. Ehlers, M.D., E.T. Fung, R.J. O'Brien & R.L. Huganir. 1998. Splice variant-specific interaction of the NMDA receptor subunit NR1 with neuronal intermediate filaments. J. Neurosci. 18: 720-730.
53. Lin, J.W., M. Wyszynski, R. Madhavan, R. Sealock, J.U. Kim & M. Sheng. 1998. Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1. J. Neurosci. 18: 2017-2027.
54. Dong, H., R.J., O'Brien, E.T. Fung, A.A. Lanahan, P.F. Worley & R.L. Huganir. 1997. GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature 386: 279-284.
55. Sheng, M. 1997. Glutamate receptors put in their place. Nature 386: 221-223.
56. Kharazia, V.N., K.D. Phend, A. Rustione & R.J. Weinberg. 1996. EM colocalization of AMPA and NMDA receptor subunits at synapses in rat cerebral cortex. Neurosci. Lett. 210: 37-40.
57. Bernard, V., P. Somogyi & J.P. Bolam. 1997. Cellular, subcellular, and subsynaptic distribution of AMPA-type glutamate receptor subunits in the neostriatum of the rat. J. Neurosci. 17: 819-833.
58. Kim, S.K. 1995. Tight junctions, membrane-associated guanylate kinases and cell signaling. Curr. Opin. Cell Biol. 7: 641-649.
59. Anderson, J.M., M.S. Balda & A.S. Fanning. 1993. The structure and regulation of tight junctions. Curr. Opin. Cell Biol. 5: 772-778.
60. Tsunoda, S., J. Sierralta, Y. Sun, R. Bodner, E. Suzuki, A. Becker, M. Socolich & C.S. Zuker. 1997. A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade. Nature 388: 243-249.