메뉴 건너뛰기




Volumn 54, Issue 5, 2012, Pages 421-429

Morphological and functional abnormalities in neuromuscular junctions of drosoph1la melanogaster induced by the expression of human app gene

Author keywords

Alzheimer disease; APP; Drosophila melanogaster; Neuromuscular junctions

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; FLUORESCENT DYE; FM 4 64; FM 4-64; PYRIDINIUM DERIVATIVE; QUATERNARY AMMONIUM DERIVATIVE; SECRETASE;

EID: 84864547092     PISSN: 00413771     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (31)
  • 1
    • 35948969760 scopus 로고    scopus 로고
    • Amyloid precursor protein and mitochondrial dysfunction in Alzheimer's disease
    • Anandatheerthavarada H. K., Devi L. 2007. Amyloid precursor protein and mitochondrial dysfunction in Alzheimer's disease. Neuroscientist. 13 :626-638.
    • (2007) Neuroscientist. , vol.13 , pp. 626-638
    • Anandatheerthavarada, H.K.1    Devi, L.2
  • 3
    • 0042035602 scopus 로고    scopus 로고
    • Human neurodegenerative disease modeling using Drosophila
    • Bonini N. M., Fortini M. E. 2003. Human neurodegenerative disease modeling using Drosophila. Annu. Rev. Neurosci. 26 : 627-56.
    • (2003) Annu. Rev. Neurosci. , vol.26 , pp. 627-656
    • Bonini, N.M.1    Fortini, M.E.2
  • 4
    • 84874287087 scopus 로고    scopus 로고
    • The fly neuromuscular junction: Structure and function. Second edition
    • San Diego: Acad. Press.
    • Budnik V, Ruiz-Canada C. 2006. The fly neuromuscular junction: structure and function. Second edition. Int. Rev. Neurobiol. V. 75. San Diego: Acad. Press. 425 p.
    • (2006) Int. Rev. Neurobiol. V. , vol.75 , pp. 425
    • Budnik, V.1    Ruiz-Canada, C.2
  • 5
    • 0035829720 scopus 로고    scopus 로고
    • Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
    • Gunawardena S., Goldstein L. S. 2001. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron. 32 : 389-401.
    • (2001) Neuron. , vol.32 , pp. 389-401
    • Gunawardena, S.1    Goldstein, L.S.2
  • 6
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J., Selkoe D. J. 2002. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. An updated summary of the amyloid hypothesis Science. 297 : 353-356.
    • (2002) An Updated Summary of the Amyloid Hypothesis Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 7
    • 23044503665 scopus 로고    scopus 로고
    • Mitochondria and neurotransmission: Evacuating the synapse
    • Hollenbeck P. J. 2005. Mitochondria and neurotransmission: evacuating the synapse. Neuron. 47 : 331-333.
    • (2005) Neuron. , vol.47 , pp. 331-333
    • Hollenbeck, P.J.1
  • 8
    • 0028136865 scopus 로고
    • Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension
    • Jin L. W., Ninomiya H, Roch J. M., Schubert D., Masliah E., Otero D. A., Saitoh T. 1994. Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension. J. Neurosci. 14 : 5461-5470.
    • (1994) J. Neurosci. , vol.14 , pp. 5461-5470
    • Jin, L.W.1    Ninomiya, H.2    Roch, J.M.3    Schubert, D.4    Masliah, E.5    Otero, D.A.6    Saitoh, T.7
  • 9
    • 0032077286 scopus 로고    scopus 로고
    • Two distinct pools of synaptic vesicles in single presynaptic boutons in a temperature-sensitive Drosophila mutant, shibre
    • Kuromi H, Kidokoro Y. 1998. Two distinct pools of synaptic vesicles in single presynaptic boutons in a temperature-sensitive Drosophila mutant, shibre. Neuron. 20 : 917-925.
    • (1998) Neuron. , vol.20 , pp. 917-925
    • Kuromi, H.1    Kidokoro, Y.2
  • 10
    • 28644449284 scopus 로고    scopus 로고
    • Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain
    • Leyssen M., Ayaz D., Hebert S. S., Reeve S., De Strooper B., Hassan B. A. 2005. Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain. EMBO J. 24:2944-2955.
    • (2005) EMBO J. , vol.24 , pp. 2944-2955
    • Leyssen, M.1    Ayaz, D.2    Hebert, S.S.3    Reeve, S.4    De Strooper, B.5    Hassan, B.A.6
  • 13
  • 16
    • 33847194657 scopus 로고    scopus 로고
    • Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity
    • Rusu P., Jansen A., Soba P., Kirsch J., Lower A., Merdes G., Kuan Y. H, Jung A., Beyreuther K., Kjaerulff O., Kins S. 2007. Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity. Eur. J. Neurosci. 25 : 1079-1086.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 1079-1086
    • Rusu, P.1    Jansen, A.2    Soba, P.3    Kirsch, J.4    Lower, A.5    Merdes, G.6    Kuan, Y.H.7    Jung, A.8    Beyreuther, K.9    Kjaerulff, O.10    Kins, S.11
  • 17
    • 77949510114 scopus 로고    scopus 로고
    • Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease
    • Sarantseva S., Timoshenko S., Bolshakova O., Karaseva E., Rodin D., Schwarzman A. L.,Vitek M. P. 2009. Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease. PIos One. 4:e8191.
    • (2009) PIos One. , vol.4
    • Sarantseva, S.1    Timoshenko, S.2    Bolshakova, O.3    Karaseva, E.4    Rodin, D.5    Schwarzman, A.L.6    Vitek, M.P.7
  • 19
    • 67349127728 scopus 로고    scopus 로고
    • FAD-mutation of APP is associated with a loss of its synaptotrop-hic activity
    • Seeger G., Gartner E., Ueberham U., Rohn S., Arendt T. 2009. FAD-mutation of APP is associated with a loss of its synaptotrop-hic activity. Neurobiol. Dis. 35 : 258-263.
    • (2009) Neurobiol. Dis. , vol.35 , pp. 258-263
    • Seeger, G.1    Gartner, E.2    Ueberham, U.3    Rohn, S.4    Arendt, T.5
  • 20
    • 0035081475 scopus 로고    scopus 로고
    • Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein
    • Selkoe D. J. 2001. Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. J. Alzhe-imers Dis. 3 : 75-80.
    • (2001) J. Alzhe-imers Dis. , vol.3 , pp. 75-80
    • Selkoe, D.J.1
  • 21
    • 33748426487 scopus 로고    scopus 로고
    • Unraveling in vivo functions of amyloid precursor protein: Insights from knockout and knockdown studies
    • Senechal Y., Larmet Y., Dev K K. 2006. Unraveling in vivo functions of amyloid precursor protein: insights from knockout and knockdown studies. Neurodegenerative Dis. 3 : 134-147.
    • (2006) Neurodegenerative Dis. , vol.3 , pp. 134-147
    • Senechal, Y.1    Larmet, Y.2    Dev, K.K.3
  • 23
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • Terry R. D., Masliah E., Salmon D. P., Butters N., DeTeresa R., Hill A., Hansen L. A., Katzman R. 1991. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann. Neurol. 30 : 572- 580.
    • (1991) Ann. Neurol. , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    DeTeresa, R.5    Hill, A.6    Hansen, L.A.7    Katzman, R.8
  • 24
    • 33846068084 scopus 로고    scopus 로고
    • Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms
    • Ting J. T, Kelley B. G., Lambert T. J. Cook D. G., Sullivan J. M. 2007. Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms. Proc. Nat. Acad. Sci. USA. 104 : 353- 358.
    • (2007) Proc. Nat. Acad. Sci. USA. , vol.104 , pp. 353-358
    • Ting, J.T.1    Kelley, B.G.2    Lambert, T.J.3    Cook, D.G.4    Sullivan, J.M.5
  • 25
    • 0033529031 scopus 로고    scopus 로고
    • Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport
    • Torroja L., Chu H, Kotovsky I., White K. 1999a. Neuronal overexpression of APPL, the Drosophila homologue of the amyloid precursor protein (APP), disrupts axonal transport. Curr. Biol. 9 :489-492.
    • (1999) Curr. Biol. , vol.9 , pp. 489-492
    • Torroja, L.1    Chu, H.2    Kotovsky, I.3    White, K.4
  • 26
    • 0033568874 scopus 로고    scopus 로고
    • The Drosophila P-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction
    • Torroja L., Packard M., Gorczyca M., White K, Budnik V. 1999b. The Drosophila P-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction. J. Neurosci. 15 : 7793-7803.
    • (1999) J. Neurosci. , vol.15 , pp. 7793-7803
    • Torroja, L.1    Packard, M.2    Gorczyca, M.3    White, K.4    Budnik, V.5
  • 27
    • 84934441648 scopus 로고    scopus 로고
    • FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction
    • Verstreken P., Ohyama T, Bellen H. J. 2008. FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction. Methods Mol. Biol. 440 : 349-369.
    • (2008) Methods Mol. Biol. , vol.440 , pp. 349-369
    • Verstreken, P.1    Ohyama, T.2    Bellen, H.J.3
  • 28
    • 5344277556 scopus 로고    scopus 로고
    • Deciphering the molecular basis of memory failure in Alzheimer's disease
    • Walsh D. M., Selkoe D. J. 2004. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron. 44 : 181- 193.
    • (2004) Neuron. , vol.44 , pp. 181-193
    • Walsh, D.M.1    Selkoe, D.J.2
  • 30
    • 0034025298 scopus 로고    scopus 로고
    • The role of mitochondria in presynaptic calcium handling at a ribbon synapse
    • Zenisek D., Matthews G. 2000. The role of mitochondria in presynaptic calcium handling at a ribbon synapse. Neuron. 25 : 229-237.
    • (2000) Neuron. , vol.25 , pp. 229-237
    • Zenisek, D.1    Matthews, G.2
  • 31
    • 0036743680 scopus 로고    scopus 로고
    • Living synaptic vesicle marker: Synaptotagmin - GFP
    • Zhang Y. Q., Rodesch C. K., Broadie K. 2002. Living synaptic vesicle marker: synaptotagmin - GFP. Genesis. 34 : 142-145.
    • (2002) Genesis. , vol.34 , pp. 142-145
    • Zhang, Y.Q.1    Rodesch, C.K.2    Broadie, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.