SCOPUS 정보 검색 플랫폼

Volumn 88, Issue 8, 2014, Pages 4180-4194

Inhibition of dengue and chikungunya virus infections by RIG-I-mediated type I interferon-independent stimulation of the innate antiviral response

(10) Olagnier, David a Scholte, Florine E M b Chiang, Cindy a Albulescu, Irina C b Nichols, Carmen b He, Zhong a Lin, Rongtuan c Snijder, Eric J b van Hemert, Martijn J b Hiscott, John a

a Vaccine and Gene Therapy Institute of Florida (United States)

b LEIDEN UNIVERSITY MEDICAL CENTER (Netherlands)

c MCGILL UNIVERSITY (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5' TRIPHOSPHORYLATED RNA; ALPHA INTERFERON RECEPTOR; ANTIVIRUS AGENT; INTERFERON; INTERFERON REGULATORY FACTOR 3; PEPTIDES AND PROTEINS; PROTEIN MAVS; PROTEIN TBK1; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHIKUNGUNYA; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; DRUG EFFICACY; DRUG SCREENING; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; IN VITRO STUDY; INFECTION PREVENTION; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; RETINOIC ACID INDUCIBLE GENE I; VIRUS REPLICATION;

ALPHAVIRUS INFECTIONS; ANIMALS; CELL LINE; CHIKUNGUNYA VIRUS; DEAD-BOX RNA HELICASES; DENGUE; DENGUE VIRUS; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; MICE; VIRUS REPLICATION;

EID: 84896993674 PISSN: 0022538X EISSN: 10985514 Source Type: Journal
DOI: 10.1128/JVI.03114-13 Document Type: Article

Times cited : (107)

References (68)

1
- 84878173821
- Cytosolic sensing of viruses
- Goubau D, Deddouche S, Reis ESC. 2013. Cytosolic sensing of viruses. Immunity 38:855-869. http://dx.doi.org/10.1016/j.immuni.2013.05.007.
- (2013) Immunity , vol.38 , pp. 855-869
- Goubau, D.¹ Deddouche, S.² Reis, E.S.C.³

2
- 32944464648
- Pathogen recognition and innate immunity
- Akira S, Uematsu S, Takeuchi O. 2006. Pathogen recognition and innate immunity. Cell 124:783-801. http://dx.doi.org/10.1016/j.cell.2006.02.015.
- (2006) Cell , vol.124 , pp. 783-801
- Akira, S.¹ Uematsu, S.² Takeuchi, O.³

3
- 79951671973
- New developments in the induction and antiviral effectors of type I interferon
- Liu SY, Sanchez DJ, Cheng G. 2011. New developments in the induction and antiviral effectors of type I interferon. Curr. Opin. Immunol. 23:57-64. http://dx.doi.org/10.1016/j.coi.2010.11.003.
- (2011) Curr. Opin. Immunol. , vol.23 , pp. 57-64
- Liu, S.Y.¹ Sanchez, D.J.² Cheng, G.³

4
- 77950343791
- Pattern recognition receptors and inflammation
- Takeuchi O, Akira S. 2010. Pattern recognition receptors and inflammation. Cell 140:805-820. http://dx.doi.org/10.1016/j.cell.2010.01.022.
- (2010) Cell , vol.140 , pp. 805-820
- Takeuchi, O.¹ Akira, S.²

5
- 80053590435
- Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter
- Belgnaoui SM, Paz S, Hiscott J. 2011. Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter. Curr. Opin. Immunol. 23:564-572. http://dx.doi.org/10.1016/j.coi.2011.08.001.
- (2011) Curr. Opin. Immunol. , vol.23 , pp. 564-572
- Belgnaoui, S.M.¹ Paz, S.² Hiscott, J.³

6
- 78751560494
- Pathogen recognition by the innate immune system
- Kumar H, Kawai T, Akira S. 2011. Pathogen recognition by the innate immune system. Int. Rev. Immunol. 30:16-34. http://dx.doi.org/10.3109/08830185.2010.529976.
- (2011) Int. Rev. Immunol. , vol.30 , pp. 16-34
- Kumar, H.¹ Kawai, T.² Akira, S.³

7
- 79956314622
- Immune signaling by RIG-I-like receptors
- Loo YM, Gale M, Jr. 2011. Immune signaling by RIG-I-like receptors. Immunity 34:680-692. http://dx.doi.org/10.1016/j.immuni.2011.05.003.
- (2011) Immunity , vol.34 , pp. 680-692
- Loo, Y.M.¹ Gale Jr., M.²

8
- 77249132637
- Recognition of viruses by cytoplasmic sensors
- Wilkins C, Gale M, Jr. 2010. Recognition of viruses by cytoplasmic sensors. Curr. Opin. Immunol. 22:41-47. http://dx.doi.org/10.1016/j.coi.2009.12.003.
- (2010) Curr. Opin. Immunol. , vol.22 , pp. 41-47
- Wilkins, C.¹ Gale Jr., M.²

9
- 74549175680
- RIGorous detection: exposing virus through RNA sensing
- Rehwinkel J, Reis e Sousa C. 2010. RIGorous detection: exposing virus through RNA sensing. Science 327:284-286. http://dx.doi.org/10.1126/science.1185068.
- (2010) Science , vol.327 , pp. 284-286
- Rehwinkel, J.¹ Reis e Sousa, C.²

10
- 75749140581
- RIG-I detects viral genomic RNA during negative-strand RNA virus infection
- Rehwinkel J, Tan CP, Goubau D, Schulz O, Pichlmair A, Bier K, Robb N, Vreede F, Barclay W, Fodor E, Reis e Sousa C. 2010. RIG-I detects viral genomic RNA during negative-strand RNA virus infection. Cell 140: 397-408. http://dx.doi.org/10.1016/j.cell.2010.01.020.
- (2010) Cell , vol.140 , pp. 397-408
- Rehwinkel, J.¹ Tan, C.P.² Goubau, D.³ Schulz, O.⁴ Pichlmair, A.⁵ Bier, K.⁶ Robb, N.⁷ Vreede, F.⁸ Barclay, W.⁹ Fodor, E.¹⁰ Reis e Sousa, C.¹¹

11
- 33750976374
- 5'-Triphosphate RNA is the ligand for RIG-I
- Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G. 2006. 5'-Triphosphate RNA is the ligand for RIG-I. Science 314:994-997. http://dx.doi.org/10.1126/science.1132505.
- (2006) Science , vol.314 , pp. 994-997
- Hornung, V.¹ Ellegast, J.² Kim, S.³ Brzozka, K.⁴ Jung, A.⁵ Kato, H.⁶ Poeck, H.⁷ Akira, S.⁸ Conzelmann, K.K.⁹ Schlee, M.¹⁰ Endres, S.¹¹ Hartmann, G.¹²

12
- 33750984771
- RIG-I-mediated antiviral responses to singlestranded RNA bearing 5'-phosphates
- Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, Weber F, Reis e Sousa C. 2006. RIG-I-mediated antiviral responses to singlestranded RNA bearing 5'-phosphates. Science 314:997-1001. http://dx.doi.org/10.1126/science.1132998.
- (2006) Science , vol.314 , pp. 997-1001
- Pichlmair, A.¹ Schulz, O.² Tan, C.P.³ Naslund, T.I.⁴ Liljestrom, P.⁵ Weber, F.⁶ Reis e Sousa, C.⁷

13
- 46949097299
- Length-dependent recognition of double-stranded ribonucleic acids by retinoic acidinducible gene-I and melanoma differentiation-associated gene 5
- Kato H, Takeuchi O, Mikamo-Satoh E, Hirai R, Kawai T, Matsushita K, Hiiragi A, Dermody TS, Fujita T, Akira S. 2008. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acidinducible gene-I and melanoma differentiation-associated gene 5. J. Exp. Med. 205:1601-1610. http://dx.doi.org/10.1084/jem.20080091.
- (2008) J. Exp. Med. , vol.205 , pp. 1601-1610
- Kato, H.¹ Takeuchi, O.² Mikamo-Satoh, E.³ Hirai, R.⁴ Kawai, T.⁵ Matsushita, K.⁶ Hiiragi, A.⁷ Dermody, T.S.⁸ Fujita, T.⁹ Akira, S.¹⁰

14
- 84859336804
- 5'-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity
- Hwang SY, Sun HY, Lee KH, Oh BH, Cha YJ, Kim BH, Yoo JY. 2012. 5'-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity. Nucleic Acids Res. 40:2724-2733. http://dx.doi.org/10.1093/nar/gkr1098.
- (2012) Nucleic Acids Res. , vol.40 , pp. 2724-2733
- Hwang, S.Y.¹ Sun, H.Y.² Lee, K.H.³ Oh, B.H.⁴ Cha, Y.J.⁵ Kim, B.H.⁶ Yoo, J.Y.⁷

15
- 68049089651
- Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus
- Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, Takeuchi O, Akira S, Tuschl T, Latz E, Ludwig J, Hartmann G. 2009. Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. Immunity 31:25-34. http://dx.doi.org/10.1016/j.immuni.2009.05.008.
- (2009) Immunity , vol.31 , pp. 25-34
- Schlee, M.¹ Roth, A.² Hornung, V.³ Hagmann, C.A.⁴ Wimmenauer, V.⁵ Barchet, W.⁶ Coch, C.⁷ Janke, M.⁸ Mihailovic, A.⁹ Wardle, G.¹⁰ Juranek, S.¹¹ Kato, H.¹² Kawai, T.¹³ Poeck, H.¹⁴ Fitzgerald, K.A.¹⁵ Takeuchi, O.¹⁶ Akira, S.¹⁷ Tuschl, T.¹⁸ Latz, E.¹⁹ Ludwig, J.²⁰ Hartmann, G.²¹ more..

16
- 3242813113
- The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
- Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5:730-737. http://dx.doi.org/10.1038/ni1087.
- (2004) Nat. Immunol. , vol.5 , pp. 730-737
- Yoneyama, M.¹ Kikuchi, M.² Natsukawa, T.³ Shinobu, N.⁴ Imaizumi, T.⁵ Miyagishi, M.⁶ Taira, K.⁷ Akira, S.⁸ Fujita, T.⁹

17
- 80054703126
- Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA
- Kowalinski E, Lunardi T, McCarthy AA, Louber J, Brunel J, Grigorov B, Gerlier D, Cusack S. 2011. Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell 147:423-435. http://dx.doi.org/10.1016/j.cell.2011.09.039.
- (2011) Cell , vol.147 , pp. 423-435
- Kowalinski, E.¹ Lunardi, T.² McCarthy, A.A.³ Louber, J.⁴ Brunel, J.⁵ Grigorov, B.⁶ Gerlier, D.⁷ Cusack, S.⁸

18
- 60749124538
- Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA
- Myong S, Cui S, Cornish PV, Kirchhofer A, Gack MU, Jung JU, Hopfner KP, Ha T. 2009. Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA. Science 323:1070-1074. http://dx.doi.org/10.1126/science.1168352.
- (2009) Science , vol.323 , pp. 1070-1074
- Myong, S.¹ Cui, S.² Cornish, P.V.³ Kirchhofer, A.⁴ Gack, M.U.⁵ Jung, J.U.⁶ Hopfner, K.P.⁷ Ha, T.⁸

19
- 84883487585
- ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon
- Patel JR, Jain A, Chou YY, Baum A, Ha T, Garcia-Sastre A. 2013. ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon. EMBO Rep. 14:780-787. http://dx.doi.org/10.1038/embor.2013.102.
- (2013) EMBO Rep. , vol.14 , pp. 780-787
- Patel, J.R.¹ Jain, A.² Chou, Y.Y.³ Baum, A.⁴ Ha, T.⁵ Garcia-Sastre, A.⁶

20
- 0036092049
- Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes
- Grandvaux N, Servant MJ, ten Oever B, Sen GC, Balachandran S, Barber GN, Lin R, Hiscott J. 2002. Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes. J. Virol. 76:5532-5539. http://dx.doi.org/10.1128/JVI.76.11.5532-5539.2002.
- (2002) J. Virol. , vol.76 , pp. 5532-5539
- Grandvaux, N.¹ Servant, M.J.² ten Oever, B.³ Sen, G.C.⁴ Balachandran, S.⁵ Barber, G.N.⁶ Lin, R.⁷ Hiscott, J.⁸

21
- 34249067693
- SnapShot: pattern-recognition receptors
- Kawai T, Akira S. 2007. SnapShot: pattern-recognition receptors. Cell 129:1024. http://dx.doi.org/10.1016/j.cell.2007.05.017.
- (2007) Cell , vol.129 , pp. 1024
- Kawai, T.¹ Akira, S.²

22
- 79956300649
- Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
- Kawai T, Akira S. 2011. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34:637-650. http://dx.doi.org/10.1016/j.immuni.2011.05.006.
- (2011) Immunity , vol.34 , pp. 637-650
- Kawai, T.¹ Akira, S.²

23
- 46249115827
- Interferon-inducible antiviral effectors
- Sadler AJ, Williams BR. 2008. Interferon-inducible antiviral effectors. Nat. Rev. Immunol. 8:559-568. http://dx.doi.org/10.1038/nri2314.
- (2008) Nat. Rev. Immunol. , vol.8 , pp. 559-568
- Sadler, A.J.¹ Williams, B.R.²

24
- 79955542915
- A diverse range of gene products are effectors of the type I interferon antiviral response
- Schoggins JW, Wilson SJ, Panis M, Murphy MY, Jones CT, Bieniasz P, Rice CM. 2011. A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472:481-485. http://dx.doi.org/10.1038/nature09907.
- (2011) Nature , vol.472 , pp. 481-485
- Schoggins, J.W.¹ Wilson, S.J.² Panis, M.³ Murphy, M.Y.⁴ Jones, C.T.⁵ Bieniasz, P.⁶ Rice, C.M.⁷

25
- 37749050365
- Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice
- Wu J, Lu M, Meng Z, Trippler M, Broering R, Szczeponek A, Krux F, Dittmer U, Roggendorf M, Gerken G, Schlaak JF. 2007. Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice. Hepatology 46:1769-1778. http://dx.doi.org/10.1002/hep.21897.
- (2007) Hepatology , vol.46 , pp. 1769-1778
- Wu, J.¹ Lu, M.² Meng, Z.³ Trippler, M.⁴ Broering, R.⁵ Szczeponek, A.⁶ Krux, F.⁷ Dittmer, U.⁸ Roggendorf, M.⁹ Gerken, G.¹⁰ Schlaak, J.F.¹¹

26
- 18744399291
- Toll-like receptor signaling inhibits hepatitis B virus replication in vivo
- Isogawa M, Robek MD, Furuichi Y, Chisari FV. 2005. Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. J. Virol. 79:7269-7272. http://dx.doi.org/10.1128/JVI.79.11.7269-7272.2005.
- (2005) J. Virol. , vol.79 , pp. 7269-7272
- Isogawa, M.¹ Robek, M.D.² Furuichi, Y.³ Chisari, F.V.⁴

27
- 34247619680
- Role of IFNalpha/beta signaling in the prevention of genital herpes virus type 2 infection
- Svensson A, Bellner L, Magnusson M, Eriksson K. 2007. Role of IFNalpha/beta signaling in the prevention of genital herpes virus type 2 infection. J. Reprod. Immunol. 74:114-123. http://dx.doi.org/10.1016/j.jri.2006.09.002.
- (2007) J. Reprod. Immunol. , vol.74 , pp. 114-123
- Svensson, A.¹ Bellner, L.² Magnusson, M.³ Eriksson, K.⁴

28
- 77952534501
- Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model
- Boukhvalova MS, Sotomayor TB, Point RC, Pletneva LM, Prince GA, Blanco JC. 2010. Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model. J. Interferon Cytokine Res. 30:229-242. http://dx.doi.org/10.1089/jir.2009.0025.
- (2010) J. Interferon Cytokine Res. , vol.30 , pp. 229-242
- Boukhvalova, M.S.¹ Sotomayor, T.B.² Point, R.C.³ Pletneva, L.M.⁴ Prince, G.A.⁵ Blanco, J.C.⁶

29
- 77956181076
- Activation of the innate immune system provides broad-spectrum protection against influenza A viruses with pandemic potential in mice
- Lau YF, Tang LH, Ooi EE, Subbarao K. 2010. Activation of the innate immune system provides broad-spectrum protection against influenza A viruses with pandemic potential in mice. Virology 406:80-87. http://dx.doi.org/10.1016/j.virol.2010.07.008.
- (2010) Virology , vol.406 , pp. 80-87
- Lau, Y.F.¹ Tang, L.H.² Ooi, E.E.³ Subbarao, K.⁴

30
- 84862181693
- Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the chikungunya virus in BEAS-2B cells
- Li YG, Siripanyaphinyo U, Tumkosit U, Noranate N, A-Nuegoonpipat A, Pan Y, Kameoka M, Kurosu T, Ikuta K, Takeda N, Anantapreecha S. 2012. Poly (I:C), an agonist of toll-like receptor-3, inhibits replication of the chikungunya virus in BEAS-2B cells. Virol. J. 9:114. http://dx.doi.org/10.1186/1743-422X-9-114.
- (2012) Virol. J. , vol.9 , pp. 114
- Li, Y.G.¹ Siripanyaphinyo, U.² Tumkosit, U.³ Noranate, N.⁴ A-Nuegoonpipat, A.⁵ Pan, Y.⁶ Kameoka, M.⁷ Kurosu, T.⁸ Ikuta, K.⁹ Takeda, N.¹⁰ Anantapreecha, S.¹¹

31
- 79961140354
- Activation of Toll-like receptor 3 impairs the dengue virus serotype 2 replication through induction of IFN-beta in cultured hepatoma cells
- Liang Z, Wu S, Li Y, He L, Wu M, Jiang L, Feng L, Zhang P, Huang X. 2011. Activation of Toll-like receptor 3 impairs the dengue virus serotype 2 replication through induction of IFN-beta in cultured hepatoma cells. PLoS One 6:e23346. http://dx.doi.org/10.1371/journal.pone.0023346.
- (2011) PLoS One , vol.6
- Liang, Z.¹ Wu, S.² Li, Y.³ He, L.⁴ Wu, M.⁵ Jiang, L.⁶ Feng, L.⁷ Zhang, P.⁸ Huang, X.⁹

32
- 58149502601
- Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G
- Trapp S, Derby NR, Singer R, Shaw A, Williams VG, Turville SG, Bess JW, Jr, Lifson JD, Robbiani M. 2009. Double-stranded RNA analog poly(I:C) inhibits human immunodeficiency virus amplification in dendritic cells via type I interferon-mediated activation of APOBEC3G. J. Virol. 83:884-895. http://dx.doi.org/10.1128/JVI.00023-08.
- (2009) J. Virol. , vol.83 , pp. 884-895
- Trapp, S.¹ Derby, N.R.² Singer, R.³ Shaw, A.⁴ Williams, V.G.⁵ Turville, S.G.⁶ Bess Jr., J.W.⁷ Lifson, J.D.⁸ Robbiani, M.⁹

33
- 70349278409
- Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells
- Wang N, Liang Y, Devaraj S, Wang J, Lemon SM, Li K. 2009. Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells. J. Virol. 83:9824-9834. http://dx.doi.org/10.1128/JVI.01125-09.
- (2009) J. Virol. , vol.83 , pp. 9824-9834
- Wang, N.¹ Liang, Y.² Devaraj, S.³ Wang, J.⁴ Lemon, S.M.⁵ Li, K.⁶

34
- 77955136134
- A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages
- Zhou Y, Wang X, Liu M, Hu Q, Song L, Ye L, Zhou D, Ho W. 2010. A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages. Immunology 131:40-49. http://dx.doi.org/10.1111/j.1365-2567.2010.03270.x.
- (2010) Immunology , vol.131 , pp. 40-49
- Zhou, Y.¹ Wang, X.² Liu, M.³ Hu, Q.⁴ Song, L.⁵ Ye, L.⁶ Zhou, D.⁷ Ho, W.⁸

35
- 84876854916
- Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity
- Goulet ML, Olagnier D, Xu Z, Paz S, Belgnaoui SM, Lafferty EI, Janelle V, Arguello M, Paquet M, Ghneim K, Richards S, Smith A, Wilkinson P, Cameron M, Kalinke U, Qureshi S, Lamarre A, Haddad EK, Sekaly RP, Peri S, Balachandran S, Lin R, Hiscott J. 2013. Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity. PLoS Pathog. 9:e1003298. http://dx.doi.org/10.1371/journal.ppat.1003 298.
- (2013) PLoS Pathog. , vol.9
- Goulet, M.L.¹ Olagnier, D.² Xu, Z.³ Paz, S.⁴ Belgnaoui, S.M.⁵ Lafferty, E.I.⁶ Janelle, V.⁷ Arguello, M.⁸ Paquet, M.⁹ Ghneim, K.¹⁰ Richards, S.¹¹ Smith, A.¹² Wilkinson, P.¹³ Cameron, M.¹⁴ Kalinke, U.¹⁵ Qureshi, S.¹⁶ Lamarre, A.¹⁷ Haddad, E.K.¹⁸ Sekaly, R.P.¹⁹ Peri, S.²⁰ more..

36
- 35748929379
- Dengue
- Halstead SB. 2007. Dengue. Lancet 370:1644-1652. http://dx.doi.org/10.1016/S0140-6736(07)61687-0.
- (2007) Lancet , vol.370 , pp. 1644-1652
- Halstead, S.B.¹

37
- 34247374654
- The burden of dengue infection
- Halstead SB, Suaya JA, Shepard DS. 2007. The burden of dengue infection. Lancet 369:1410-1411. http://dx.doi.org/10.1016/S0140-6736(07)6 0645-X.
- (2007) Lancet , vol.369 , pp. 1410-1411
- Halstead, S.B.¹ Suaya, J.A.² Shepard, D.S.³

38
- 79960835805
- Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms
- Rothman AL. 2011. Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms. Nat. Rev. Immunol. 11:532-543. http://dx.doi.org/10.1038/nri3014.
- (2011) Nat. Rev. Immunol. , vol.11 , pp. 532-543
- Rothman, A.L.¹

39
- 77953552629
- Biology and pathogenesis of chikungunya virus
- Schwartz O, Albert ML. 2010. Biology and pathogenesis of chikungunya virus. Nat. Rev. Microbiol. 8:491-500. http://dx.doi.org/10.1038/nrmicro 2368.
- (2010) Nat. Rev. Microbiol. , vol.8 , pp. 491-500
- Schwartz, O.¹ Albert, M.L.²

40
- 71949104808
- Chikungunya: a bending reality
- Her Z, Kam YW, Lin RT, Ng LF. 2009. Chikungunya: a bending reality. Microbes Infect. 11:1165-1176. http://dx.doi.org/10.1016/j.micinf.2009.09.004.
- (2009) Microbes Infect. , vol.11 , pp. 1165-1176
- Her, Z.¹ Kam, Y.W.² Lin, R.T.³ Ng, L.F.⁴

41
- 34548241400
- Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus
- Powers AM, Logue CH. 2007. Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus. J. Gen. Virol. 88:2363-2377. http://dx.doi.org/10.1099/vir.0.82858-0.
- (2007) J. Gen. Virol. , vol.88 , pp. 2363-2377
- Powers, A.M.¹ Logue, C.H.²

42
- 84880970577
- Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates
- Scholte FE, Tas A, Martina BE, Cordioli P, Narayanan K, Makino S, Snijder EJ, van Hemert MJ. 2013. Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates. PLoS One 8:e71047. http://dx.doi.org/10.1371/journal.pone.0071047.
- (2013) PLoS One , vol.8
- Scholte, F.E.¹ Tas, A.² Martina, B.E.³ Cordioli, P.⁴ Narayanan, K.⁵ Makino, S.⁶ Snijder, E.J.⁷ van Hemert, M.J.⁸

43
- 79960561094
- Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells
- Metz SW, Geertsema C, Martina BE, Andrade P, Heldens JG, van Oers MM, Goldbach RW, Vlak JM, Pijlman GP. 2011. Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells. Virol. J. 8:353. http://dx.doi.org/10.1186/1743-422X-8-353.
- (2011) Virol. J. , vol.8 , pp. 353
- Metz, S.W.¹ Geertsema, C.² Martina, B.E.³ Andrade, P.⁴ Heldens, J.G.⁵ van Oers, M.M.⁶ Goldbach, R.W.⁷ Vlak, J.M.⁸ Pijlman, G.P.⁹

44
- 84868102239
- DENV inhibits type I IFN production in infected cells by cleaving human STING
- Aguirre S, Maestre AM, Pagni S, Patel JR, Savage T, Gutman D, Maringer K, Bernal-Rubio D, Shabman RS, Simon V, Rodriguez-Madoz JR, Mulder LC, Barber GN, Fernandez-Sesma A. 2012. DENV inhibits type I IFN production in infected cells by cleaving human STING. PLoS Pathog. 8:e1002934. http://dx.doi.org/10.1371/journal.ppat.1002 934.
- (2012) PLoS Pathog. , vol.8
- Aguirre, S.¹ Maestre, A.M.² Pagni, S.³ Patel, J.R.⁴ Savage, T.⁵ Gutman, D.⁶ Maringer, K.⁷ Bernal-Rubio, D.⁸ Shabman, R.S.⁹ Simon, V.¹⁰ Rodriguez-Madoz, J.R.¹¹ Mulder, L.C.¹² Barber, G.N.¹³ Fernandez-Sesma, A.¹⁴

45
- 84858989721
- Innate immunity evasion by dengue virus
- Morrison J, Aguirre S, Fernandez-Sesma A. 2012. Innate immunity evasion by dengue virus. Viruses 4:397-413. http://dx.doi.org/10.3390/v4030397.
- (2012) Viruses , vol.4 , pp. 397-413
- Morrison, J.¹ Aguirre, S.² Fernandez-Sesma, A.³

46
- 77956859036
- Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex
- Rodriguez-Madoz JR, Belicha-Villanueva A, Bernal-Rubio D, Ashour J, Ayllon J, Fernandez-Sesma A. 2010. Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex. J. Virol. 84:9760-9774. http://dx.doi.org/10.1128/JVI.01051-10.
- (2010) J. Virol. , vol.84 , pp. 9760-9774
- Rodriguez-Madoz, J.R.¹ Belicha-Villanueva, A.² Bernal-Rubio, D.³ Ashour, J.⁴ Ayllon, J.⁵ Fernandez-Sesma, A.⁶

47
- 37049009945
- Primary human splenic macrophages, but not T or B cells, are the principal target cells for dengue virus infection in vitro
- Blackley S, Kou Z, Chen H, Quinn M, Rose RC, Schlesinger JJ, Coppage M, Jin X. 2007. Primary human splenic macrophages, but not T or B cells, are the principal target cells for dengue virus infection in vitro. J. Virol. 81:13325-13334. http://dx.doi.org/10.1128/JVI.01568-07.
- (2007) J. Virol. , vol.81 , pp. 13325-13334
- Blackley, S.¹ Kou, Z.² Chen, H.³ Quinn, M.⁴ Rose, R.C.⁵ Schlesinger, J.J.⁶ Coppage, M.⁷ Jin, X.⁸

48
- 36849074407
- Monocytes, but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells
- Kou Z, Quinn M, Chen H, Rodrigo WW, Rose RC, Schlesinger JJ, Jin X. 2008. Monocytes, but not T or B cells, are the principal target cells for dengue virus (DV) infection among human peripheral blood mononuclear cells. J. Med. Virol. 80:134-146. http://dx.doi.org/10.1002/jmv.21051.
- (2008) J. Med. Virol. , vol.80 , pp. 134-146
- Kou, Z.¹ Quinn, M.² Chen, H.³ Rodrigo, W.W.⁴ Rose, R.C.⁵ Schlesinger, J.J.⁶ Jin, X.⁷

49
- 0033881444
- Infection of human cells by dengue virus is modulated by different cell types and viral strains
- Diamond MS, Edgil D, Roberts TG, Lu B, Harris E. 2000. Infection of human cells by dengue virus is modulated by different cell types and viral strains. J. Virol. 74:7814-7823. http://dx.doi.org/10.1128/JVI.74.17.7814-7823.2000.
- (2000) J. Virol. , vol.74 , pp. 7814-7823
- Diamond, M.S.¹ Edgil, D.² Roberts, T.G.³ Lu, B.⁴ Harris, E.⁵

50
- 34347342849
- Characterization of reemerging chikungunya virus
- Sourisseau M, Schilte C, Casartelli N, Trouillet C, Guivel-Benhassine F, Rudnicka D, Sol-Foulon N, Le Roux K, Prevost MC, Fsihi H, Frenkiel MP, Blanchet F, Afonso PV, Ceccaldi PE, Ozden S, Gessain A, Schuffenecker I, Verhasselt B, Zamborlini A, Saib A, Rey FA, Arenzana-Seisdedos F, Despres P, Michault A, Albert ML, Schwartz O. 2007. Characterization of reemerging chikungunya virus. PLoS Pathog. 3:e89. http://dx.doi.org/10.1371/journal.ppat.0030089.
- (2007) PLoS Pathog. , vol.3
- Sourisseau, M.¹ Schilte, C.² Casartelli, N.³ Trouillet, C.⁴ Guivel-Benhassine, F.⁵ Rudnicka, D.⁶ Sol-Foulon, N.⁷ Le Roux, K.⁸ Prevost, M.C.⁹ Fsihi, H.¹⁰ Frenkiel, M.P.¹¹ Blanchet, F.¹² Afonso, P.V.¹³ Ceccaldi, P.E.¹⁴ Ozden, S.¹⁵ Gessain, A.¹⁶ Schuffenecker, I.¹⁷ Verhasselt, B.¹⁸ Zamborlini, A.¹⁹ Saib, A.²⁰ more..

51
- 0032889018
- New mouse model for dengue virus vaccine testing
- Johnson AJ, Roehrig JT. 1999. New mouse model for dengue virus vaccine testing. J. Virol. 73:783-786.
- (1999) J. Virol. , vol.73 , pp. 783-786
- Johnson, A.J.¹ Roehrig, J.T.²

52
- 40349087268
- A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease
- Couderc T, Chretien F, Schilte C, Disson O, Brigitte M, Guivel-Benhassine F, Touret Y, Barau G, Cayet N, Schuffenecker I, Despres P, Arenzana-Seisdedos F, Michault A, Albert ML, Lecuit M. 2008. A mouse model for Chikungunya: young age and inefficient type-I interferon signaling are risk factors for severe disease. PLoS Pathog. 4:e29. http://dx.doi.org/10.1371/journal.ppat.0040029.
- (2008) PLoS Pathog. , vol.4
- Couderc, T.¹ Chretien, F.² Schilte, C.³ Disson, O.⁴ Brigitte, M.⁵ Guivel-Benhassine, F.⁶ Touret, Y.⁷ Barau, G.⁸ Cayet, N.⁹ Schuffenecker, I.¹⁰ Despres, P.¹¹ Arenzana-Seisdedos, F.¹² Michault, A.¹³ Albert, M.L.¹⁴ Lecuit, M.¹⁵

53
- 77149120482
- Type I IFN controls chikungunya virus via its action on nonhematopoietic cells
- Schilte C, Couderc T, Chretien F, Sourisseau M, Gangneux N, Guivel-Benhassine F, Kraxner A, Tschopp J, Higgs S, Michault A, Arenzana-Seisdedos F, Colonna M, Peduto L, Schwartz O, Lecuit M, Albert ML. 2010. Type I IFN controls chikungunya virus via its action on nonhematopoietic cells. J. Exp. Med. 207:429-442. http://dx.doi.org/10.1084/jem.20090851.
- (2010) J. Exp. Med. , vol.207 , pp. 429-442
- Schilte, C.¹ Couderc, T.² Chretien, F.³ Sourisseau, M.⁴ Gangneux, N.⁵ Guivel-Benhassine, F.⁶ Kraxner, A.⁷ Tschopp, J.⁸ Higgs, S.⁹ Michault, A.¹⁰ Arenzana-Seisdedos, F.¹¹ Colonna, M.¹² Peduto, L.¹³ Schwartz, O.¹⁴ Lecuit, M.¹⁵ Albert, M.L.¹⁶

54
- 79851492362
- RIG-I, MDA5 and TLR3 synergistically play an important role in restric-tion of dengue virus infection
- Nasirudeen AM, Wong HH, Thien P, Xu S, Lam KP, Liu DX. 2011. RIG-I, MDA5 and TLR3 synergistically play an important role in restric-tion of dengue virus infection. PLoS Negl. Trop. Dis. 5:e926. http://dx.doi.org/10.1371/journal.pntd.0000926.
- (2011) PLoS Negl. Trop. Dis. , vol.5
- Nasirudeen, A.M.¹ Wong, H.H.² Thien, P.³ Xu, S.⁴ Lam, K.P.⁵ Liu, D.X.⁶

55
- 72549116887
- The IFITM proteins mediate cellular resistance to influenzaAH1N1 virus, West Nile virus, and dengue virus
- Brass AL, Huang IC, Benita Y, John SP, Krishnan MN, Feeley EM, Ryan BJ, Weyer JL, van der Weyden L, Fikrig E, Adams DJ, Xavier RJ, Farzan M, Elledge SJ. 2009. The IFITM proteins mediate cellular resistance to influenzaAH1N1 virus, West Nile virus, and dengue virus. Cell 139:1243-1254. http://dx.doi.org/10.1016/j.cell.2009.12.017.
- (2009) Cell , vol.139 , pp. 1243-1254
- Brass, A.L.¹ Huang, I.C.² Benita, Y.³ John, S.P.⁴ Krishnan, M.N.⁵ Feeley, E.M.⁶ Ryan, B.J.⁷ Weyer, J.L.⁸ van der Weyden, L.⁹ Fikrig, E.¹⁰ Adams, D.J.¹¹ Xavier, R.J.¹² Farzan, M.¹³ Elledge, S.J.¹⁴

56
- 84870518676
- Viperin restricts chikungunya virus replication and pathology
- Teng TS, Foo SS, Simamarta D, Lum FM, Teo TH, Lulla A, Yeo NK, Koh EG, Chow A, Leo YS, Merits A, Chin KC, Ng LF. 2012. Viperin restricts chikungunya virus replication and pathology. J. Clin. Investig. 122:4447-4460. http://dx.doi.org/10.1172/JCI63120.
- (2012) J. Clin. Investig. , vol.122 , pp. 4447-4460
- Teng, T.S.¹ Foo, S.S.² Simamarta, D.³ Lum, F.M.⁴ Teo, T.H.⁵ Lulla, A.⁶ Yeo, N.K.⁷ Koh, E.G.⁸ Chow, A.⁹ Leo, Y.S.¹⁰ Merits, A.¹¹ Chin, K.C.¹² Ng, L.F.¹³

57
- 84876848344
- Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin
- Helbig KJ, Carr JM, Calvert JK, Wati S, Clarke JN, Eyre NS, Narayana SK, Fiches GN, McCartney EM, Beard MR. 2013. Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin. PLoS Negl. Trop. Dis. 7:e2178. http://dx.doi.org/10.1371/journal.pntd.0002178.
- (2013) PLoS Negl. Trop. Dis. , vol.7
- Helbig, K.J.¹ Carr, J.M.² Calvert, J.K.³ Wati, S.⁴ Clarke, J.N.⁵ Eyre, N.S.⁶ Narayana, S.K.⁷ Fiches, G.N.⁸ McCartney, E.M.⁹ Beard, M.R.¹⁰

58
- 84355162855
- CpG and poly(I:C) stimulation of dendritic cells and fibroblasts limits herpes simplex virus type 1 infection in an IFNbeta-dependent and-independent way
- Gaajetaan GR, Geelen TH, Grauls GE, Bruggeman CA, Stassen FR. 2012. CpG and poly(I:C) stimulation of dendritic cells and fibroblasts limits herpes simplex virus type 1 infection in an IFNbeta-dependent and-independent way. Antiviral Res. 93:39-47. http://dx.doi.org/10.1016/j.antiviral.2011.10.015.
- (2012) Antiviral Res. , vol.93 , pp. 39-47
- Gaajetaan, G.R.¹ Geelen, T.H.² Grauls, G.E.³ Bruggeman, C.A.⁴ Stassen, F.R.⁵

59
- 84861541638
- Protective role of Toll-like receptor 3-induced type I interferon in murine coronavirus infection of macrophages
- Mazaleuskaya L, Veltrop R, Ikpeze N, Martin-Garcia J, Navas-Martin S. 2012. Protective role of Toll-like receptor 3-induced type I interferon in murine coronavirus infection of macrophages. Viruses 4:901-923. http://dx.doi.org/10.3390/v4050901.
- (2012) Viruses , vol.4 , pp. 901-923
- Mazaleuskaya, L.¹ Veltrop, R.² Ikpeze, N.³ Martin-Garcia, J.⁴ Navas-Martin, S.⁵

60
- 79955784340
- Decreased dengue replication and an increased anti-viral humoral response with the use of combined Toll-like receptor 3 and 7/8 agonists in macaques
- Sariol CA, Martinez MI, Rivera F, Rodriguez IV, Pantoja P, Abel K, Arana T, Giavedoni L, Hodara V, White LJ, Anglero YI, Montaner LJ, Kraiselburd EN. 2011. Decreased dengue replication and an increased anti-viral humoral response with the use of combined Toll-like receptor 3 and 7/8 agonists in macaques. PLoS One 6:e19323. http://dx.doi.org/10.1371/journal.pone.0019323.
- (2011) PLoS One , vol.6
- Sariol, C.A.¹ Martinez, M.I.² Rivera, F.³ Rodriguez, I.V.⁴ Pantoja, P.⁵ Abel, K.⁶ Arana, T.⁷ Giavedoni, L.⁸ Hodara, V.⁹ White, L.J.¹⁰ Anglero, Y.I.¹¹ Montaner, L.J.¹² Kraiselburd, E.N.¹³

61
- 84869023304
- Intranasal treatment with poly(I · C) protects aged mice from lethal respiratory virus infections
- Zhao J, Wohlford-Lenane C, Zhao J, Fleming E, Lane TE, McCray PB, Jr, Perlman S. 2012. Intranasal treatment with poly(I · C) protects aged mice from lethal respiratory virus infections. J. Virol. 86:11416-11424. http://dx.doi.org/10.1128/JVI.01410-12.
- (2012) J. Virol. , vol.86 , pp. 11416-11424
- Zhao, J.¹ Wohlford-Lenane, C.² Zhao, J.³ Fleming, E.⁴ Lane, T.E.⁵ McCray Jr., P.B.⁶ Perlman, S.⁷

62
- 84855486511
- Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
- Caskey M, Lefebvre F, Filali-Mouhim A, Cameron MJ, Goulet JP, Haddad EK, Breton G, Trumpfheller C, Pollak S, Shimeliovich I, Duque-Alarcon A, Pan L, Nelkenbaum A, Salazar AM, Schlesinger SJ, Steinman RM, Sekaly RP. 2011. Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans. J. Exp. Med. 208:2357-2366. http://dx.doi.org/10.1084/jem.20111171.
- (2011) J. Exp. Med. , vol.208 , pp. 2357-2366
- Caskey, M.¹ Lefebvre, F.² Filali-Mouhim, A.³ Cameron, M.J.⁴ Goulet, J.P.⁵ Haddad, E.K.⁶ Breton, G.⁷ Trumpfheller, C.⁸ Pollak, S.⁹ Shimeliovich, I.¹⁰ Duque-Alarcon, A.¹¹ Pan, L.¹² Nelkenbaum, A.¹³ Salazar, A.M.¹⁴ Schlesinger, S.J.¹⁵ Steinman, R.M.¹⁶ Sekaly, R.P.¹⁷

63
- 35148824709
- Intranasal immunization with H5N1 vaccine plus poly I:poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge
- Ichinohe T, Kawaguchi A, Tamura S, Takahashi H, Sawa H, Ninomiya A, Imai M, Itamura S, Odagiri T, Tashiro M, Chiba J, Sata T, Kurata T, Hasegawa H. 2007. Intranasal immunization with H5N1 vaccine plus poly I:poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge. Microbes Infect. 9:1333-1340. http://dx.doi.org/10.1016/j.micinf.2007.06.007.
- (2007) Microbes Infect. , vol.9 , pp. 1333-1340
- Ichinohe, T.¹ Kawaguchi, A.² Tamura, S.³ Takahashi, H.⁴ Sawa, H.⁵ Ninomiya, A.⁶ Imai, M.⁷ Itamura, S.⁸ Odagiri, T.⁹ Tashiro, M.¹⁰ Chiba, J.¹¹ Sata, T.¹² Kurata, T.¹³ Hasegawa, H.¹⁴

64
- 13944257660
- Synthetic double-stranded RNA poly(I:C) combined with mucosal vaccine protects against influenza virus infection
- Ichinohe T, Watanabe I, Ito S, Fujii H, Moriyama M, Tamura S, Takahashi H, Sawa H, Chiba J, Kurata T, Sata T, Hasegawa H. 2005. Synthetic double-stranded RNA poly(I:C) combined with mucosal vaccine protects against influenza virus infection. J. Virol. 79:2910-2919. http://dx.doi.org/10.1128/JVI.79.5.2910-2919.2005.
- (2005) J. Virol. , vol.79 , pp. 2910-2919
- Ichinohe, T.¹ Watanabe, I.² Ito, S.³ Fujii, H.⁴ Moriyama, M.⁵ Tamura, S.⁶ Takahashi, H.⁷ Sawa, H.⁸ Chiba, J.⁹ Kurata, T.¹⁰ Sata, T.¹¹ Hasegawa, H.¹²

65
- 84873046317
- A Sendai virus-derived RNA agonist of RIG-I as a virus vaccine adjuvant
- Martinez-Gil L, GoffPH, Hai R, Garcia-Sastre A, Shaw ML, Palese P. 2013. A Sendai virus-derived RNA agonist of RIG-I as a virus vaccine adjuvant. J. Virol. 87:1290-1300. http://dx.doi.org/10.1128/JVI.02338-12.
- (2013) J. Virol. , vol.87 , pp. 1290-1300
- Martinez-Gil, L.¹ Goff, P.H.² Hai, R.³ Garcia-Sastre, A.⁴ Shaw, M.L.⁵ Palese, P.⁶

66
- 65249155463
- Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells
- Dejean AS, Beisner DR, Ch'en IL, Kerdiles YM, Babour A, Arden KC, Castrillon DH, DePinho RA, Hedrick SM. 2009. Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nat. Immunol. 10:504-513. http://dx.doi.org/10.1038/ni.1729.
- (2009) Nat. Immunol. , vol.10 , pp. 504-513
- Dejean, A.S.¹ Beisner, D.R.² Ch'en, I.L.³ Kerdiles, Y.M.⁴ Babour, A.⁵ Arden, K.C.⁶ Castrillon, D.H.⁷ DePinho, R.A.⁸ Hedrick, S.M.⁹

67
- 47949127385
- IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity
- Maher SG, Sheikh F, Scarzello AJ, Romero-Weaver AL, Baker DP, Donnelly RP, Gamero AM. 2008. IFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activity. Cancer Biol. Ther. 7:1109-1115. http://dx.doi.org/10.4161/cbt.7.7.6192.
- (2008) Cancer Biol. Ther. , vol.7 , pp. 1109-1115
- Maher, S.G.¹ Sheikh, F.² Scarzello, A.J.³ Romero-Weaver, A.L.⁴ Baker, D.P.⁵ Donnelly, R.P.⁶ Gamero, A.M.⁷

68
- 20044384901
- Murine interferon lambdas (type III interferons) exhibit potent antiviral activity in vivo in a poxvirus infection model
- Bartlett NW, Buttigieg K, Kotenko SV, Smith GL. 2005. Murine interferon lambdas (type III interferons) exhibit potent antiviral activity in vivo in a poxvirus infection model. J. Gen. Virol. 86:1589-1596. http://dx.doi.org/10.1099/vir.0.80904-0.
- (2005) J. Gen. Virol. , vol.86 , pp. 1589-1596
- Bartlett, N.W.¹ Buttigieg, K.² Kotenko, S.V.³ Smith, G.L.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.