5′-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity

Nucleic Acids Research

Volumn 40, Issue 6, 2012, Pages 2724-2733

  Hwang, Sun Young ^a   Sun, Hwa Young ^a   Lee, Kwang Hoon ^b   Oh, Byung Ha ^b   Cha, Yu Jin ^a   Kim, Byeang Hyean ^a   Yoo, Joo Yeon ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; APTAMER; BETA INTERFERON; HELICASE; POLYURIDYLIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I; ANTIVIRUS AGENT; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; POLYPHOSPHATE; RNA; TRIPHOSPHORIC ACID;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG SCREENING; GENETIC SCREENING; INFLUENZA VIRUS; NEWCASTLE DISEASE PARAMYXOVIRUS; NONHUMAN; NUCLEOTIDE MOTIF; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; VESICULAR STOMATITIS VIRUS; VIRAL GENE THERAPY; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS REPLICATION; BIOSYNTHESIS; CELL LINE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG EFFECT; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

NEWCASTLE DISEASE VIRUS; ORTHOMYXOVIRIDAE; VESICULAR STOMATITIS VIRUS;

ANTIVIRAL AGENTS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CELL LINE; DEAD-BOX RNA HELICASES; HUMANS; INTERFERON-BETA; MOLECULAR SEQUENCE DATA; POLY U; POLYPHOSPHATES; RNA; SELEX APTAMER TECHNIQUE; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84859336804     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr1098     Document Type: Article

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