-
1
-
-
79959905757
-
T regulatory cells participate in the control of germinal centre reactions
-
Alexander, C.M., L.T. Tygrett, A.W. Boyden, K.L. Wolniak, K.L. Legge, and T.J. Waldschmidt. 2011. T regulatory cells participate in the control of germinal centre reactions. Immunology. 133:452-468. http://dx.doi.org/10.1111/j.1365-2567.2011.03456.x
-
(2011)
Immunology
, vol.133
, pp. 452-468
-
-
Alexander, C.M.1
Tygrett, L.T.2
Boyden, A.W.3
Wolniak, K.L.4
Legge, K.L.5
Waldschmidt, T.J.6
-
2
-
-
84861423126
-
Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
-
Ballesteros-Tato, A., B. León, B.A. Graf, A. Moquin, P.S. Adams, F.E. Lund, and T.D. Randall. 2012. Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation. Immunity. 36:847-856. http://dx.doi.org/10.1016/j.immuni.2012.02.012
-
(2012)
Immunity
, vol.36
, pp. 847-856
-
-
Ballesteros-tato, A.1
León, B.2
Graf, B.A.3
Moquin, A.4
Adams, P.S.5
Lund, F.E.6
Randall, T.D.7
-
3
-
-
0031897801
-
Defective TCR expression in transgenic mice constructed using cDNA-based alphaand beta-chain genes under the control of heterologous regulatory elements
-
Barnden, M.J., J. Allison, W.R. Heath, and F.R. Carbone. 1998. Defective TCR expression in transgenic mice constructed using cDNA-based alphaand beta-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76:34-40. http://dx.doi.org/10.1046/j.1440-1711.1998.00709.x
-
(1998)
Immunol. Cell Biol
, vol.76
, pp. 34-40
-
-
Barnden, M.J.1
Allison, J.2
Heath, W.R.3
Carbone, F.R.4
-
4
-
-
58449124804
-
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
-
Bauquet, A.T., H. Jin, A.M. Paterson, M. Mitsdoerffer, I.C. Ho, A.H. Sharpe, and V.K. Kuchroo. 2009. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat. Immunol. 10:167-175. http://dx.doi.org/10.1038/ni.1690
-
(2009)
Nat. Immunol
, vol.10
, pp. 167-175
-
-
Bauquet, A.T.1
Jin, H.2
Paterson, A.M.3
Mitsdoerffer, M.4
Ho, I.C.5
Sharpe, A.H.6
Kuchroo, V.K.7
-
5
-
-
79955731369
-
NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network
-
Bhattacharyya, S., J. Deb, A.K. Patra, D.A. Thuy Pham, W. Chen, M. Vaeth, F. Berberich-Siebelt, S. Klein-Hessling, E.D. Lamperti, K. Reifenberg, et al. 2011. NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network. J. Exp. Med. 208:823-839. http://dx.doi.org/10.1084/jem.20100945
-
(2011)
J. Exp. Med
, vol.208
, pp. 823-839
-
-
Bhattacharyya, S.1
Deb, J.2
Patra, A.K.3
Thuy Pham, D.A.4
Chen, W.5
Vaeth, M.6
Berberich-siebelt, F.7
Klein-hessling, S.8
Lamperti, E.D.9
Reifenberg, K.10
-
6
-
-
84862143798
-
Cyclic AMP underpins suppression by regulatory T cells
-
Bodor, J., T. Bopp, M. Vaeth, M. Klein, E. Serfling, T. Hünig, C. Becker, H. Schild, and E. Schmitt. 2012. Cyclic AMP underpins suppression by regulatory T cells. Eur. J. Immunol. 42:1375-1384. http://dx.doi.org/10.1002/eji.201141578
-
(2012)
Eur. J. Immunol
, vol.42
, pp. 1375-1384
-
-
Bodor, J.1
Bopp, T.2
Vaeth, M.3
Klein, M.4
Serfling, E.5
Hünig, T.6
Becker, C.7
Schild, H.8
Schmitt, E.9
-
7
-
-
84861872906
-
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation
-
Bollig, N., A. Brüstle, K. Kellner, W. Ackermann, E. Abass, H. Raifer, B. Camara, C. Brendel, G. Giel, E. Bothur, et al. 2012. Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation. Proc. Natl. Acad. Sci. USA. 109:8664-8669. http://dx.doi.org/10.1073/pnas.1205834109
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 8664-8669
-
-
Bollig, N.1
Brüstle, A.2
Kellner, K.3
Ackermann, W.4
Abass, E.5
Raifer, H.6
Camara, B.7
Brendel, C.8
Giel, G.9
Bothur, E.10
-
8
-
-
45849145442
-
Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)
-
Bonelli, M., A. Savitskaya, K. von Dalwigk, C.W. Steiner, D. Aletaha, J.S. Smolen, and C. Scheinecker. 2008. Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE). Int. Immunol. 20:861-868. http://dx.doi.org/10.1093/intimm/dxn044
-
(2008)
Int. Immunol
, vol.20
, pp. 861-868
-
-
Bonelli, M.1
Savitskaya, A.2
Von Dalwigk, K.3
Steiner, C.W.4
Aletaha, D.5
Smolen, J.S.6
Scheinecker, C.7
-
10
-
-
34250376423
-
Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression
-
Bopp, T., C. Becker, M. Klein, S. Klein-Hessling, A. Palmetshofer, E. Serfling, V. Heib, M. Becker, J. Kubach, S. Schmitt, et al. 2007. Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression. J. Exp. Med. 204:1303-1310. http://dx.doi.org/10.1084/jem.20062129
-
(2007)
J. Exp. Med
, vol.204
, pp. 1303-1310
-
-
Bopp, T.1
Becker, C.2
Klein, M.3
Klein-hessling, S.4
Palmetshofer, A.5
Serfling, E.6
Heib, V.7
Becker, M.8
Kubach, J.9
Schmitt, S.10
-
11
-
-
70049113279
-
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner
-
Chaudhry, A., D. Rudra, P. Treuting, R.M. Samstein, Y. Liang, A. Kas, and A.Y. Rudensky. 2009. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. Science. 326:986-991. http://dx.doi.org/10.1126/science.1172702
-
(2009)
Science
, vol.326
, pp. 986-991
-
-
Chaudhry, A.1
Rudra, D.2
Treuting, P.3
Samstein, R.M.4
Liang, Y.5
Kas, A.6
Rudensky, A.Y.7
-
12
-
-
2942755979
-
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
-
Chtanova, T., S.G. Tangye, R. Newton, N. Frank, M.R. Hodge, M.S. Rolph, and C.R. Mackay. 2004. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J. Immunol. 173:68-78.
-
(2004)
J. Immunol
, vol.173
, pp. 68-78
-
-
Chtanova, T.1
Tangye, S.G.2
Newton, R.3
Frank, N.4
Hodge, M.R.5
Rolph, M.S.6
Mackay, C.R.7
-
13
-
-
79961158055
-
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
-
Chung, Y., S. Tanaka, F. Chu, R.I. Nurieva, G.J. Martinez, S. Rawal, Y.H. Wang, H. Lim, J.M. Reynolds, X.H. Zhou, et al. 2011. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat. Med. 17:983-988. http://dx.doi.org/10.1038/nm.2426
-
(2011)
Nat. Med
, vol.17
, pp. 983-988
-
-
Chung, Y.1
Tanaka, S.2
Chu, F.3
Nurieva, R.I.4
Martinez, G.J.5
Rawal, S.6
Wang, Y.H.7
Lim, H.8
Reynolds, J.M.9
Zhou, X.H.10
-
14
-
-
18444365894
-
Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis
-
Chuvpilo, S., E. Jankevics, D. Tyrsin, A. Akimzhanov, D. Moroz, M.K. Jha, J. Schulze-Luehrmann, B. Santner-Nanan, E. Feoktistova, T. König, et al. 2002. Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis. Immunity. 16:881-895. http://dx.doi.org/10.1016/S1074-7613(02)00329-1
-
(2002)
Immunity
, vol.16
, pp. 881-895
-
-
Chuvpilo, S.1
Jankevics, E.2
Tyrsin, D.3
Akimzhanov, A.4
Moroz, D.5
Jha, M.K.6
Schulze-luehrmann, J.7
Santner-nanan, B.8
Feoktistova, E.9
König, T.10
-
15
-
-
79952955744
-
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
-
Cretney, E., A. Xin, W. Shi, M. Minnich, F. Masson, M. Miasari, G.T. Belz, G.K. Smyth, M. Busslinger, S.L. Nutt, and A. Kallies. 2011. The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat. Immunol. 12:304- 311. http://dx.doi.org/10.1038/ni.2006
-
(2011)
Nat. Immunol
, vol.12
, pp. 304-311
-
-
Cretney, E.1
Xin, A.2
Shi, W.3
Minnich, M.4
Masson, F.5
Miasari, M.6
Belz, G.T.7
Smyth, G.K.8
Busslinger, M.9
Nutt, S.L.10
Kallies, A.11
-
16
-
-
84873160951
-
Differentiation and function of Foxp3(+) effector regulatory T cells
-
Cretney, E., A. Kallies, and S.L. Nutt. 2013. Differentiation and function of Foxp3(+) effector regulatory T cells. Trends Immunol. 34:74-80. http://dx.doi.org/10.1016/j.it.2012.11.002
-
(2013)
Trends Immunol
, vol.34
, pp. 74-80
-
-
Cretney, E.1
Kallies, A.2
Nutt, S.L.3
-
17
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty, S. 2011. Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29:621- 663. http://dx.doi.org/10.1146/annurev-immunol-031210-101400
-
(2011)
Annu. Rev. Immunol
, vol.29
-
-
Crotty, S.1
-
18
-
-
78951473630
-
NFAT and IRF proteins regulate transcription of the anti-HIV gene, APOBEC3G
-
Farrow, M.A., E.Y. Kim, S.M. Wolinsky, and A.M. Sheehy. 2011. NFAT and IRF proteins regulate transcription of the anti-HIV gene, APOBEC3G. J. Biol. Chem. 286:2567-2577. http://dx.doi.org/10.1074/jbc.M110.154377
-
(2011)
J. Biol. Chem
, vol.286
, pp. 2567-2577
-
-
Farrow, M.A.1
Kim, E.Y.2
Wolinsky, S.M.3
Sheehy, A.M.4
-
19
-
-
36048978911
-
Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature
-
Hill, J.A., M. Feuerer, K. Tash, S. Haxhinasto, J. Perez, R. Melamed, D. Mathis, and C. Benoist. 2007. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity. 27:786-800. http://dx.doi.org/10.1016/j.immuni.2007.09.010
-
(2007)
Immunity
, vol.27
, pp. 786-800
-
-
Hill, J.A.1
Feuerer, M.2
Tash, K.3
Haxhinasto, S.4
Perez, J.5
Melamed, R.6
Mathis, D.7
Benoist, C.8
-
20
-
-
0030604714
-
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
-
Ho, I.C., M.R. Hodge, J.W. Rooney, and L.H. Glimcher. 1996. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell. 85:973-983. http://dx.doi.org/10.1016/S0092-8674(00)81299-4
-
(1996)
Cell
, vol.85
, pp. 973-983
-
-
Ho, I.C.1
Hodge, M.R.2
Rooney, J.W.3
Glimcher, L.H.4
-
21
-
-
84874254070
-
NFATc1 induction in peripheral T and B lymphocytes
-
Hock, M., M. Vaeth, R. Rudolf, A.K. Patra, D.A.T. Pham, K. Muhammad, T. Pusch, T. Bopp, E. Schmitt, R. Rost, et al. 2013. NFATc1 induction in peripheral T and B lymphocytes. J. Immunol. 190:2345-2353.
-
(2013)
J. Immunol
, vol.190
, pp. 2345-2353
-
-
Hock, M.1
Vaeth, M.2
Rudolf, R.3
Patra, A.K.4
Pham, D.A.T.5
Muhammad, K.6
Pusch, T.7
Bopp, T.8
Schmitt, E.9
Rost, R.10
-
22
-
-
79956081339
-
The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells
-
Ise, W., M. Kohyama, B.U. Schraml, T. Zhang, B. Schwer, U. Basu, F.W. Alt, J. Tang, E.M. Oltz, T.L. Murphy, and K.M. Murphy. 2011. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells. Nat. Immunol. 12:536-543.
-
(2011)
Nat. Immunol
, vol.12
, pp. 536-543
-
-
Ise, W.1
Kohyama, M.2
Schraml, B.U.3
Zhang, T.4
Schwer, B.5
Basu, U.6
Alt, F.W.7
Tang, J.8
Oltz, E.M.9
Murphy, T.L.10
Murphy, K.M.11
-
23
-
-
33747067459
-
Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout
-
Jasinski, J.M., L. Yu, M. Nakayama, M.M. Li, M.A. Lipes, G.S. Eisenbarth, and E. Liu. 2006. Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout. Diabetes. 55:1978-1984. http://dx.doi.org/10.2337/db06-0058
-
(2006)
Diabetes
, vol.55
, pp. 1978-1984
-
-
Jasinski, J.M.1
Yu, L.2
Nakayama, M.3
Li, M.M.4
Lipes, M.A.5
Eisenbarth, G.S.6
Liu, E.7
-
24
-
-
69249109601
-
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
-
Johnston, R.J., A.C. Poholek, D. DiToro, I. Yusuf, D. Eto, B. Barnett, A.L. Dent, J. Craft, and S. Crotty. 2009. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science. 325:1006-1010. http://dx.doi.org/10.1126/science.1175870
-
(2009)
Science
, vol.325
, pp. 1006-1010
-
-
Johnston, R.J.1
Poholek, A.C.2
DiToro, D.3
Yusuf, I.4
Eto, D.5
Barnett, B.6
Dent, A.L.7
Craft, J.8
Crotty, S.9
-
25
-
-
84863116170
-
STAT5 is a potent negative regulator of TFH cell differentiation
-
Johnston, R.J., Y.S. Choi, J.A. Diamond, J.A. Yang, and S. Crotty. 2012. STAT5 is a potent negative regulator of TFH cell differentiation. J. Exp. Med. 209:243-250. http://dx.doi.org/10.1084/jem.20111174
-
(2012)
J. Exp. Med
, vol.209
, pp. 243-250
-
-
Johnston, R.J.1
Choi, Y.S.2
Diamond, J.A.3
Yang, J.A.4
Crotty, S.5
-
26
-
-
84859416933
-
Regulatory T cells: mechanisms of differentiation and function
-
Josefowicz, S.Z., L.F. Lu, and A.Y. Rudensky. 2012. Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 30:531-564. http://dx.doi.org/10.1146/annurev.immunol.25.022106.141623
-
(2012)
Annu. Rev. Immunol
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
-
27
-
-
0037443487
-
Protein kinase A regulates GATA-3-dependent activation of IL-5 gene expression in Th2 cells
-
Klein-Hessling, S., M.K. Jha, B. Santner-Nanan, F. Berberich-Siebelt, T. Baumruker, A. Schimpl, and E. Serfling. 2003. Protein kinase A regulates GATA-3-dependent activation of IL-5 gene expression in Th2 cells. J. Immunol. 170:2956-2961.
-
(2003)
J. Immunol
, vol.170
, pp. 2956-2961
-
-
Klein-hessling, S.1
Jha, M.K.2
Santner-nanan, B.3
Berberich-siebelt, F.4
Baumruker, T.5
Schimpl, A.6
Serfling, E.7
-
28
-
-
57649217417
-
Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter
-
Klein-Hessling, S., T. Bopp, M.K. Jha, A. Schmidt, S. Miyatake, E. Schmitt, and E. Serfling. 2008. Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter. J. Biol. Chem. 283:31030-31037. http://dx.doi.org/10.1074/jbc.M805929200
-
(2008)
J. Biol. Chem
, vol.283
, pp. 31030-31037
-
-
Klein-hessling, S.1
Bopp, T.2
Jha, M.K.3
Schmidt, A.4
Miyatake, S.5
Schmitt, E.6
Serfling, E.7
-
29
-
-
65749103365
-
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
-
Koch, M.A., G. Tucker-Heard, N.R. Perdue, J.R. Killebrew, K.B. Urdahl, and D.J. Campbell. 2009. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat. Immunol. 10:595-602. http://dx.doi.org/10.1038/ni.1731
-
(2009)
Nat. Immunol
, vol.10
, pp. 595-602
-
-
Koch, M.A.1
Tucker-heard, G.2
Perdue, N.R.3
Killebrew, J.R.4
Urdahl, K.B.5
Campbell, D.J.6
-
30
-
-
84859711533
-
Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation
-
Kroenke, M.A., D. Eto, M. Locci, M. Cho, T. Davidson, E.K. Haddad, and S. Crotty. 2012. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J. Immunol. 188:3734-3744. http://dx.doi.org/10.4049/jimmunol.1103246
-
(2012)
J. Immunol
, vol.188
, pp. 3734-3744
-
-
Kroenke, M.A.1
Eto, D.2
Locci, M.3
Cho, M.4
Davidson, T.5
Haddad, E.K.6
Crotty, S.7
-
31
-
-
6344272894
-
B lymphocyte-induced maturation protein (Blimp)-1, IFN regulatory factor (IRF)-1, and IRF-2 can bind to the same regulatory sites
-
Kuo, T.C., and K.L. Calame. 2004. B lymphocyte-induced maturation protein (Blimp)-1, IFN regulatory factor (IRF)-1, and IRF-2 can bind to the same regulatory sites. J. Immunol. 173:5556-5563.
-
(2004)
J. Immunol
, vol.173
, pp. 5556-5563
-
-
Kuo, T.C.1
Calame, K.L.2
-
32
-
-
0345505646
-
Inhibition of Th2 differentiation and GATA-3 expression by BCL-6
-
Kusam, S., L.M. Toney, H. Sato, and A.L. Dent. 2003. Inhibition of Th2 differentiation and GATA-3 expression by BCL-6. J. Immunol. 170: 2435-2441.
-
(2003)
J. Immunol
, vol.170
, pp. 2435-2441
-
-
Kusam, S.1
Toney, L.M.2
Sato, H.3
Dent, A.L.4
-
33
-
-
71749089605
-
Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors
-
Kwon, H., D. Thierry-Mieg, J. Thierry-Mieg, H.P. Kim, J. Oh, C. Tunyaplin, S. Carotta, C.E. Donovan, M.L. Goldman, P. Tailor, et al. 2009. Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. Immunity. 31:941-952. http://dx.doi.org/10.1016/j.immuni.2009.10.008
-
(2009)
Immunity
, vol.31
, pp. 941-952
-
-
Kwon, H.1
Thierry-mieg, D.2
Thierry-mieg, J.3
Kim, H.P.4
Oh, J.5
Tunyaplin, C.6
Carotta, S.7
Donovan, C.E.8
Goldman, M.L.9
Tailor, P.10
-
34
-
-
33846423147
-
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
-
Lahl, K., C. Loddenkemper, C. Drouin, J. Freyer, J. Arnason, G. Eberl, A. Hamann, H. Wagner, J. Huehn, and T. Sparwasser. 2007. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J. Exp. Med. 204:57-63. http://dx.doi.org/10.1084/jem.20061852
-
(2007)
J. Exp. Med
, vol.204
, pp. 57-63
-
-
Lahl, K.1
Loddenkemper, C.2
Drouin, C.3
Freyer, J.4
Arnason, J.5
Eberl, G.6
Hamann, A.7
Wagner, H.8
Huehn, J.9
Sparwasser, T.10
-
35
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee, P.P., D.R. Fitzpatrick, C. Beard, H.K. Jessup, S. Lehar, K.W. Makar, M. Pérez-Melgosa, M.T. Sweetser, M.S. Schlissel, S. Nguyen, et al. 2001. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity. 15:763-774. http://dx.doi.org/10.1016/S1074-7613(01)00227-8
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
Pérez-melgosa, M.7
Sweetser, M.T.8
Schlissel, M.S.9
Nguyen, S.10
-
36
-
-
2942598529
-
Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin
-
Li, H., Y.Y. Zhang, Y.N. Sun, X.Y. Huang, Y.F. Jia, and D. Li. 2004. Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin. Acta Pharmacol. Sin. 25:807-811.
-
(2004)
Acta Pharmacol. Sin
, vol.25
, pp. 807-811
-
-
Li, H.1
Zhang, Y.Y.2
Sun, Y.N.3
Huang, X.Y.4
Jia, Y.F.5
Li, D.6
-
37
-
-
25444497719
-
Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells
-
Lim, H.W., P. Hillsamer, A.H. Banham, and C.H. Kim. 2005. Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells. J. Immunol. 175:4180-4183.
-
(2005)
J. Immunol
, vol.175
, pp. 4180-4183
-
-
Lim, H.W.1
Hillsamer, P.2
Banham, A.H.3
Kim, C.H.4
-
38
-
-
79961151137
-
Foxp3+ follicular regulatory T cells control the germinal center response
-
Linterman, M.A., W. Pierson, S.K. Lee, A. Kallies, S. Kawamoto, T.F. Rayner, M. Srivastava, D.P. Divekar, L. Beaton, J.J. Hogan, et al. 2011. Foxp3+ follicular regulatory T cells control the germinal center response. Nat. Med. 17:975-982. http://dx.doi.org/10.1038/nm.2425
-
(2011)
Nat. Med
, vol.17
, pp. 975-982
-
-
Linterman, M.A.1
Pierson, W.2
Lee, S.K.3
Kallies, A.4
Kawamoto, S.5
Rayner, T.F.6
Srivastava, M.7
Divekar, D.P.8
Beaton, L.9
Hogan, J.J.10
-
39
-
-
84870285173
-
Bcl6 expression specifies the T follicular helper cell program in vivo
-
S1-S24
-
Liu, X., X. Yan, B. Zhong, R.I. Nurieva, A. Wang, X. Wang, N. Martin- Orozco, Y. Wang, S.H. Chang, E. Esplugues, et al. 2012. Bcl6 expression specifies the T follicular helper cell program in vivo. J. Exp. Med. 209:1841-1852: S1-S24. http://dx.doi.org/10.1084/jem.20120219
-
(2012)
J. Exp. Med
, vol.209
, pp. 1841-1852
-
-
Liu, X.1
Yan, X.2
Zhong, B.3
Nurieva, R.I.4
Wang, A.5
Wang, X.6
Martin-orozco, N.7
Wang, Y.8
Chang, S.H.9
Esplugues, E.10
-
40
-
-
84864303294
-
The origins, function, and regulation of T follicular helper cells
-
Ma, C.S., E.K. Deenick, M. Batten, and S.G. Tangye. 2012. The origins, function, and regulation of T follicular helper cells. J. Exp. Med. 209:1241-1253. http://dx.doi.org/10.1084/jem.20120994
-
(2012)
J. Exp. Med
, vol.209
, pp. 1241-1253
-
-
Ma, C.S.1
Deenick, E.K.2
Batten, M.3
Tangye, S.G.4
-
41
-
-
0028176488
-
Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells
-
McCaffrey, P.G., P.K. Kim, V.E. Valge-Archer, R. Sen, and A. Rao. 1994. Cyclosporin A sensitivity of the NF-kappa B site of the IL2R alpha promoter in untransformed murine T cells. Nucleic Acids Res. 22:2134-2142. http://dx.doi.org/10.1093/nar/22.11.2134
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 2134-2142
-
-
McCaffrey, P.G.1
Kim, P.K.2
Valge-archer, V.E.3
Sen, R.4
Rao, A.5
-
42
-
-
77956175013
-
NFAT, immunity and cancer: a transcription factor comes of age
-
Müller, M.R., and A. Rao. 2010. NFAT, immunity and cancer: a transcription factor comes of age. Nat. Rev. Immunol. 10:645-656. http://dx.doi.org/10.1038/nri2818
-
(2010)
Nat. Rev. Immunol
, vol.10
, pp. 645-656
-
-
Müller, M.R.1
Rao, A.2
-
43
-
-
67449102913
-
Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase
-
Nayak, A., J. Glöckner-Pagel, M. Vaeth, J.E. Schumann, M. Buttmann, T. Bopp, E. Schmitt, E. Serfling, and F. Berberich-Siebelt. 2009. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J. Biol. Chem. 284:10935-10946. http://dx.doi.org/10.1074/jbc.M900465200
-
(2009)
J. Biol. Chem
, vol.284
, pp. 10935-10946
-
-
Nayak, A.1
Glöckner-pagel, J.2
Vaeth, M.3
Schumann, J.E.4
Buttmann, M.5
Bopp, T.6
Schmitt, E.7
Serfling, E.8
Berberich-siebelt, F.9
-
44
-
-
84858706847
-
Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
-
Oestreich, K.J., S.E. Mohn, and A.S. Weinmann. 2012. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat. Immunol. 13:405- 411. http://dx.doi.org/10.1038/ni.2242
-
(2012)
Nat. Immunol
, vol.13
, pp. 405-411
-
-
Oestreich, K.J.1
Mohn, S.E.2
Weinmann, A.S.3
-
45
-
-
0035129248
-
NFATc1 and NFATc2 together control both T and B cell activation and differentiation
-
Peng, S.L., A.J. Gerth, A.M. Ranger, and L.H. Glimcher. 2001. NFATc1 and NFATc2 together control both T and B cell activation and differentiation. Immunity. 14:13-20. http://dx.doi.org/10.1016/S1074-7613(01)00085-1
-
(2001)
Immunity
, vol.14
, pp. 13-20
-
-
Peng, S.L.1
Gerth, A.J.2
Ranger, A.M.3
Glimcher, L.H.4
-
46
-
-
24144442910
-
Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA
-
Qiao, B., J. Wu, Y.W. Chu, Y. Wang, D.P. Wang, H.S. Wu, and S.D. Xiong. 2005. Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA. Rheumatology (Oxford). 44:1108-1114. http://dx.doi.org/10.1093/rheumatology/keh656
-
(2005)
Rheumatology (Oxford
, vol.44
, pp. 1108-1114
-
-
Qiao, B.1
Wu, J.2
Chu, Y.W.3
Wang, Y.4
Wang, D.P.5
Wu, H.S.6
Xiong, S.D.7
-
47
-
-
0031933037
-
Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc
-
Ranger, A.M., M.R. Hodge, E.M. Gravallese, M. Oukka, L. Davidson, F.W. Alt, F.C. de la Brousse, T. Hoey, M. Grusby, and L.H. Glimcher. 1998. Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc. Immunity. 8:125-134. http://dx.doi.org/10.1016/S1074-7613(00)80465-3
-
(1998)
Immunity
, vol.8
, pp. 125-134
-
-
Ranger, A.M.1
Hodge, M.R.2
Gravallese, E.M.3
Oukka, M.4
Davidson, L.5
Alt, F.W.6
De la Brousse, F.C.7
Hoey, T.8
Grusby, M.9
Glimcher, L.H.10
-
48
-
-
33746256850
-
Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression
-
Rasheed, A.U., H.P. Rahn, F. Sallusto, M. Lipp, and G. Müller. 2006. Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression. Eur. J. Immunol. 36:1892-1903. http://dx.doi.org/10.1002/eji.200636136
-
(2006)
Eur. J. Immunol
, vol.36
, pp. 1892-1903
-
-
Rasheed, A.U.1
Rahn, H.P.2
Sallusto, F.3
Lipp, M.4
Müller, G.5
-
49
-
-
0037089575
-
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
-
Rengarajan, J., K.A. Mowen, K.D. McBride, E.D. Smith, H. Singh, and L.H. Glimcher. 2002a. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J. Exp. Med. 195:1003-1012. http://dx.doi.org/10.1084/jem.20011128
-
(2002)
J. Exp. Med
, vol.195
, pp. 1003-1012
-
-
Rengarajan, J.1
Mowen, K.A.2
McBride, K.D.3
Smith, E.D.4
Singh, H.5
Glimcher, L.H.6
-
50
-
-
0036144744
-
NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells
-
Rengarajan, J., B. Tang, and L.H. Glimcher. 2002b. NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells. Nat. Immunol. 3:48-54. http://dx.doi.org/10.1038/ni744
-
(2002)
Nat. Immunol
, vol.3
, pp. 48-54
-
-
Rengarajan, J.1
Tang, B.2
Glimcher, L.H.3
-
51
-
-
84872685720
-
The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood
-
Sage, P.T., L.M. Francisco, C.V. Carman, and A.H. Sharpe. 2013. The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood. Nat. Immunol. 14:152-161. http://dx.doi.org/10.1038/ni.2496
-
(2013)
Nat. Immunol
, vol.14
, pp. 152-161
-
-
Sage, P.T.1
Francisco, L.M.2
Carman, C.V.3
Sharpe, A.H.4
-
52
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi, S., T. Yamaguchi, T. Nomura, and M. Ono. 2008. Regulatory T cells and immune tolerance. Cell. 133:775-787. http://dx.doi.org/10.1016/j.cell.2008.05.009
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
53
-
-
56249125984
-
Blimp-1Deltaexon7: a naturally occurring Blimp-1 deletion mutant with auto-regulatory potential
-
Schmidt, D., A. Nayak, J.E. Schumann, A. Schimpl, I. Berberich, and F. Berberich-Siebelt. 2008. Blimp-1Deltaexon7: a naturally occurring Blimp-1 deletion mutant with auto-regulatory potential. Exp. Cell Res. 314:3614-3627. http://dx.doi.org/10.1016/j.yexcr.2008.09.008
-
(2008)
Exp. Cell Res
, vol.314
, pp. 3614-3627
-
-
Schmidt, D.1
Nayak, A.2
Schumann, J.E.3
Schimpl, A.4
Berberich, I.5
Berberich-siebelt, F.6
-
54
-
-
0034693087
-
-
Biochim. Biophys. Acta
-
Serfling, E., F. Berberich-Siebelt, S. Chuvpilo, E. Jankevics, S. Klein- Hessling, T. Twardzik, and A. Avots. 2000. The role of NF-AT transcription factors in T cell activation and differentiation. Biochim. Biophys. Acta. 1498:1-18. http://dx.doi.org/10.1016/S0167-4889(00)00082-3
-
(2000)
The role of NF-AT transcription factors in T cell activation and differentiation
-
-
Serfling, E.1
Berberich-siebelt, F.2
Chuvpilo, S.3
Jankevics, E.4
Klein-hessling, S.5
Twardzik, T.6
Avots, A.7
-
55
-
-
84865267868
-
NFATc1/αA: The other Face of NFAT Factors in Lymphocytes
-
Serfling, E., A. Avots, S. Klein-Hessling, R. Rudolf, M. Vaeth, and F. Berberich-Siebelt. 2012. NFATc1/αA: The other Face of NFAT Factors in Lymphocytes. Cell Commun. Signal. 10:16. http://dx.doi.org/10.1186/1478-811X-10-16
-
(2012)
Cell Commun. Signal
, vol.10
, pp. 16
-
-
Serfling, E.1
Avots, A.2
Klein-hessling, S.3
Rudolf, R.4
Vaeth, M.5
Berberich-siebelt, F.6
-
56
-
-
18444395232
-
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
-
Shaffer, A.L., K.I. Lin, T.C. Kuo, X. Yu, E.M. Hurt, A. Rosenwald, J.M. Giltnane, L. Yang, H. Zhao, K. Calame, and L.M. Staudt. 2002. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity. 17:51-62. http://dx.doi.org/10.1016/S1074-7613(02)00335-7
-
(2002)
Immunity
, vol.17
, pp. 51-62
-
-
Shaffer, A.L.1
Lin, K.I.2
Kuo, T.C.3
Yu, X.4
Hurt, E.M.5
Rosenwald, A.6
Giltnane, J.M.7
Yang, L.8
Zhao, H.9
Calame, K.10
Staudt, L.M.11
-
57
-
-
74849138095
-
Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
-
Simpson, N., P.A. Gatenby, A. Wilson, S. Malik, D.A. Fulcher, S.G. Tangye, H. Manku, T.J. Vyse, G. Roncador, G.A. Huttley, et al. 2010. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum. 62:234-244. http://dx.doi.org/10.1002/art.25032
-
(2010)
Arthritis Rheum
, vol.62
, pp. 234-244
-
-
Simpson, N.1
Gatenby, P.A.2
Wilson, A.3
Malik, S.4
Fulcher, D.A.5
Tangye, S.G.6
Manku, H.7
Vyse, T.J.8
Roncador, G.9
Huttley, G.A.10
-
58
-
-
79952291184
-
Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)
-
Vaeth, M., T. Gogishvili, T. Bopp, M. Klein, F. Berberich-Siebelt, S. Gattenloehner, A. Avots, T. Sparwasser, N. Grebe, E. Schmitt, et al. 2011. Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1). Proc. Natl. Acad. Sci. USA. 108:2480-2485. http://dx.doi.org/10.1073/pnas.1009463108
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 2480-2485
-
-
Vaeth, M.1
Gogishvili, T.2
Bopp, T.3
Klein, M.4
Berberich-siebelt, F.5
Gattenloehner, S.6
Avots, A.7
Sparwasser, T.8
Grebe, N.9
Schmitt, E.10
-
59
-
-
84867088968
-
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells
-
Vaeth, M., U. Schliesser, G. Müller, S. Reissig, K. Satoh, A. Tuettenberg, H. Jonuleit, A. Waisman, M.R. Müller, E. Serfling, et al. 2012. Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells. Proc. Natl. Acad. Sci. USA. 109:16258-16263. http://dx.doi.org/10.1073/pnas.1203870109
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 16258-16263
-
-
Vaeth, M.1
Schliesser, U.2
Müller, G.3
Reissig, S.4
Satoh, K.5
Tuettenberg, A.6
Jonuleit, H.7
Waisman, A.8
Müller, M.R.9
Serfling, E.10
-
60
-
-
33846900430
-
Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus
-
Valencia, X., C. Yarboro, G. Illei, and P.E. Lipsky. 2007. Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus. J. Immunol. 178:2579-2588.
-
(2007)
J. Immunol
, vol.178
, pp. 2579-2588
-
-
Valencia, X.1
Yarboro, C.2
Illei, G.3
Lipsky, P.E.4
-
61
-
-
1542314250
-
A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression
-
Wang, J., and A. Yen. 2004. A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression. Mol. Cell. Biol. 24:2423- 2443. http://dx.doi.org/10.1128/MCB.24.6.2423-2443.2004
-
(2004)
Mol. Cell. Biol
, vol.24
-
-
Wang, J.1
Yen, A.2
-
62
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
Wing, K., Y. Onishi, P. Prieto-Martin, T. Yamaguchi, M. Miyara, Z. Fehervari, T. Nomura, and S. Sakaguchi. 2008. CTLA-4 control over Foxp3+ regulatory T cell function. Science. 322:271-275. http://dx.doi.org/10.1126/science.1160062
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
Nomura, T.7
Sakaguchi, S.8
-
63
-
-
0032582656
-
Downstream activation of a TATA-less promoter by Oct-2, Bob1, and NF-kappaB directs expression of the homing receptor BLR1 to mature B cells
-
Wolf, I., V. Pevzner, E. Kaiser, G. Bernhardt, E. Claudio, U. Siebenlist, R. Förster, and M. Lipp. 1998. Downstream activation of a TATA-less promoter by Oct-2, Bob1, and NF-kappaB directs expression of the homing receptor BLR1 to mature B cells. J. Biol. Chem. 273:28831- 28836. http://dx.doi.org/10.1074/jbc.273.44.28831
-
(1998)
J. Biol. Chem
, vol.273
, pp. 28831-28836
-
-
Wolf, I.1
Pevzner, V.2
Kaiser, E.3
Bernhardt, G.4
Claudio, E.5
Siebenlist, U.6
Förster, R.7
Lipp, M.8
-
64
-
-
80555133319
-
Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells
-
Wollenberg, I., A. Agua-Doce, A. Hernández, C. Almeida, V.G. Oliveira, J. Faro, and L. Graca. 2011. Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells. J. Immunol. 187:4553-4560. http://dx.doi.org/10.4049/jimmunol.1101328
-
(2011)
J. Immunol
, vol.187
, pp. 4553-4560
-
-
Wollenberg, I.1
Agua-doce, A.2
Hernández, A.3
Almeida, C.4
Oliveira, V.G.5
Faro, J.6
Graca, L.7
-
65
-
-
70049101558
-
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
-
Yu, D., S. Rao, L.M. Tsai, S.K. Lee, Y. He, E.L. Sutcliffe, M. Srivastava, M. Linterman, L. Zheng, N. Simpson, et al. 2009. The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity. 31:457-468. http://dx.doi.org/10.1016/j.immuni.2009.07.002
-
(2009)
Immunity
, vol.31
, pp. 457-468
-
-
Yu, D.1
Rao, S.2
Tsai, L.M.3
Lee, S.K.4
He, Y.5
Sutcliffe, E.L.6
Srivastava, M.7
Linterman, M.8
Zheng, L.9
Simpson, N.10
-
66
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Zheng, Y., S.Z. Josefowicz, A. Kas, T.T. Chu, M.A. Gavin, and A.Y. Rudensky. 2007. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature. 445:936-940. http://dx.doi.org/10.1038/nature05563
-
(2007)
Nature
, vol.445
, pp. 936-940
-
-
Zheng, Y.1
Josefowicz, S.Z.2
Kas, A.3
Chu, T.T.4
Gavin, M.A.5
Rudensky, A.Y.6
|