-
1
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi, S., Yamaguchi, T., Nomura, T. and Ono, M., Regulatory T cells and immune tolerance. Cell 2008. 133: 775-787.
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
2
-
-
25844504653
-
Developmental regulation of Foxp3 expression during ontogeny
-
Fontenot, J. D., Dooley, J. L., Farr, A. G. and Rudensky, A. Y., Developmental regulation of Foxp3 expression during ontogeny. J. Exp. Med. 2005. 202: 901-906.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 901-906
-
-
Fontenot, J.D.1
Dooley, J.L.2
Farr, A.G.3
Rudensky, A.Y.4
-
3
-
-
84859416933
-
Regulatory T cells: mechanisms of differentiation and function
-
Josefowicz, S. Z., Lu, L-F. and Rudensky, A. Y., Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 2012. 30: 531-564.
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.-F.2
Rudensky, A.Y.3
-
4
-
-
0030007975
-
cAMP inducibility of transcriptional repressor ICER in developing and mature human T lymphocytes
-
Bodor, J., Spetz, A. L., Strominger, J. L. and Habener, J. F., cAMP inducibility of transcriptional repressor ICER in developing and mature human T lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 1996. 93: 3536-3541.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 3536-3541
-
-
Bodor, J.1
Spetz, A.L.2
Strominger, J.L.3
Habener, J.F.4
-
6
-
-
0026494982
-
Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression
-
Nabavi, N., Freeman, G. J., Gault, A., Godfrey, D., Nadler, L. M. and Glimcher, L. H., Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression. Nature 1992. 360: 266-268.
-
(1992)
Nature
, vol.360
, pp. 266-268
-
-
Nabavi, N.1
Freeman, G.J.2
Gault, A.3
Godfrey, D.4
Nadler, L.M.5
Glimcher, L.H.6
-
7
-
-
39449126502
-
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
-
Tang, Q. and Bluestone, J. A., The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 2008. 9: 239-244.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 239-244
-
-
Tang, Q.1
Bluestone, J.A.2
-
8
-
-
0027741257
-
Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor
-
Molina, C. A., Foulkes, N. S., Lalli, E. and Sassone-Corsi, P., Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell 1993. 75: 875-886.
-
(1993)
Cell
, vol.75
, pp. 875-886
-
-
Molina, C.A.1
Foulkes, N.S.2
Lalli, E.3
Sassone-Corsi, P.4
-
9
-
-
34250376423
-
Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression
-
Bopp, T., Becker, C., Klein, M., Klein-Hessling, S., Palmetshofer, A., Serfling, E., Heib, V. et al., Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression. J. Exp. Med. 2007. 204: 1303-1310.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1303-1310
-
-
Bopp, T.1
Becker, C.2
Klein, M.3
Klein-Hessling, S.4
Palmetshofer, A.5
Serfling, E.6
Heib, V.7
-
11
-
-
0033840025
-
Suppression of T cell function: a potential role for transcriptional repressor ICER
-
Bodor, J., Bodorova, J. and Gress, R., Suppression of T cell function: a potential role for transcriptional repressor ICER. J. Leukoc. Biol. 2000. 67: 774-779.
-
(2000)
J. Leukoc. Biol.
, vol.67
, pp. 774-779
-
-
Bodor, J.1
Bodorova, J.2
Gress, R.3
-
12
-
-
34249701932
-
ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells
-
Bodor, J., Fehervari, Z., Diamond, B. and Sakaguchi, S., ICER/CREM-mediated transcriptional attenuation of IL-2 and its role in suppression by regulatory T cells. Eur. J. Immunol. 2007. 37: 884-895.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 884-895
-
-
Bodor, J.1
Fehervari, Z.2
Diamond, B.3
Sakaguchi, S.4
-
13
-
-
0034978987
-
Suppression of T-cell responsiveness by inducible cAMP early repressor (ICER)
-
Bodor, J., Feigenbaum, L., Bodorova, J., Bare, C., Reitz, M. and Gress, R., Suppression of T-cell responsiveness by inducible cAMP early repressor (ICER). J. Leukoc. Biol. 2001 69: 1053-1059.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 1053-1059
-
-
Bodor, J.1
Feigenbaum, L.2
Bodorova, J.3
Bare, C.4
Reitz, M.5
Gress, R.6
-
14
-
-
0030043836
-
Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB
-
Barton, K., Muthusamy, N., Chanyangam, M., Fischer, C., Clendenin, C. and Leiden, J. M., Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature 1996. 379: 81-85.
-
(1996)
Nature
, vol.379
, pp. 81-85
-
-
Barton, K.1
Muthusamy, N.2
Chanyangam, M.3
Fischer, C.4
Clendenin, C.5
Leiden, J.M.6
-
16
-
-
46249101518
-
How regulatory T cells work
-
Vignali, D. A., Collison, L. W. and Workman, C. J., How regulatory T cells work. Nat. Rev. Immunol. 2008. 8: 523-532.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 523-532
-
-
Vignali, D.A.1
Collison, L.W.2
Workman, C.J.3
-
17
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 1998. 188: 287-296.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.1
Shevach, E.2
-
18
-
-
33847153417
-
Foxp3-dependent programme of regulatory T-cell differentiation
-
Gavin, M. A., Rasmussen, J. P., Fontenot, J. D., Vasta, V., Manganiello, V. C., Beavo, J. A. and Rudensky, A. Y., Foxp3-dependent programme of regulatory T-cell differentiation. Nature 2007. 445: 771-775.
-
(2007)
Nature
, vol.445
, pp. 771-775
-
-
Gavin, M.A.1
Rasmussen, J.P.2
Fontenot, J.D.3
Vasta, V.4
Manganiello, V.C.5
Beavo, J.A.6
Rudensky, A.Y.7
-
19
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
-
Zheng, Y., Josefowicz, S., Chaudhry, A., Peng, X. P., Forbush, K. and Rudensky, A. Y., Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010. 463: 808-812.
-
(2010)
Nature
, vol.463
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
21
-
-
58149263148
-
T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3′,5′-cyclic monophosphate
-
Conche, C., Boulla, G., Trautmann, A. and Randriamampita, C., T cell adhesion primes antigen receptor-induced calcium responses through a transient rise in adenosine 3′, 5′-cyclic monophosphate. Immunity 2009. 30: 33-43.
-
(2009)
Immunity
, vol.30
, pp. 33-43
-
-
Conche, C.1
Boulla, G.2
Trautmann, A.3
Randriamampita, C.4
-
23
-
-
70449464560
-
Waking up regulatory T cells
-
Taskén, K., Waking up regulatory T cells. Blood 2009. 114: 1136-1137.
-
(2009)
Blood
, vol.114
, pp. 1136-1137
-
-
Taskén, K.1
-
24
-
-
10344258606
-
The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes
-
Mehlmann, L. M., Saeki, Y., Tanaka, S., Brennan, T. J., Evsikov, A. V., Pendola, F. L., Knowles, B. B. et al., The Gs-linked receptor GPR3 maintains meiotic arrest in mammalian oocytes. Science 2004. 306: 1947-1950.
-
(2004)
Science
, vol.306
, pp. 1947-1950
-
-
Mehlmann, L.M.1
Saeki, Y.2
Tanaka, S.3
Brennan, T.J.4
Evsikov, A.V.5
Pendola, F.L.6
Knowles, B.B.7
-
26
-
-
34447265236
-
CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation
-
Kim, H. P. and Leonard, W. J., CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J. Exp. Med. 2007. 204: 1543-1551.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1543-1551
-
-
Kim, H.P.1
Leonard, W.J.2
-
27
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. and Sakaguchi, S., Control of regulatory T cell development by the transcription factor Foxp3. Science 2003. 299: 1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
28
-
-
79952291184
-
Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)
-
Vaeth, M., Gogishvili, T., Bopp, T., Klein, M., Berberich-Siebelt, F., Gattenloehner, S., Avots, A. et al., Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1). Proc. Natl. Acad. Sci. U.S.A. 2011. 108: 2480-2485.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 2480-2485
-
-
Vaeth, M.1
Gogishvili, T.2
Bopp, T.3
Klein, M.4
Berberich-Siebelt, F.5
Gattenloehner, S.6
Avots, A.7
-
29
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Zheng, Y., Josefowicz, S. Z., Kas, A., Chu, T.-T., Gavin, M. A. and Rudensky, A. Y., Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 2007. 445: 936-940.
-
(2007)
Nature
, vol.445
, pp. 936-940
-
-
Zheng, Y.1
Josefowicz, S.Z.2
Kas, A.3
Chu, T.-T.4
Gavin, M.A.5
Rudensky, A.Y.6
-
30
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
Marson, A., Kretschmer, K., Frampton, G. M., Jacobsen, E. S., Polansky, J. K., MacIsaac, K. D., Levine, S. S. et al., Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature 2007. 445: 931-935.
-
(2007)
Nature
, vol.445
, pp. 931-935
-
-
Marson, A.1
Kretschmer, K.2
Frampton, G.M.3
Jacobsen, E.S.4
Polansky, J.K.5
MacIsaac, K.D.6
Levine, S.S.7
-
31
-
-
42149169184
-
Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target
-
Sojka, D. K., Huang, Y.-H. and Fowell, D. J., Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target. Immunology 2008. 124: 13-22.
-
(2008)
Immunology
, vol.124
, pp. 13-22
-
-
Sojka, D.K.1
Huang, Y.-H.2
Fowell, D.J.3
-
32
-
-
77955876612
-
Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells
-
Cardone, J., Le Friec, G., Vantourout, P., Roberts, A., Fuchs, A., Jackson, I., Suddason, T. et al., Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells. Nat. Immunol. 2010. 9: 862-871.
-
(2010)
Nat. Immunol.
, vol.9
, pp. 862-871
-
-
Cardone, J.1
Le Friec, G.2
Vantourout, P.3
Roberts, A.4
Fuchs, A.5
Jackson, I.6
Suddason, T.7
-
33
-
-
0034978987
-
Suppression of T cell-responsiveness by inducible cAMP early repressor (ICER)
-
Bodor, J., Feigenbaum, L., Bodorova, J., Bare, C., Reitz, M. S. and Gress, R. E., Suppression of T cell-responsiveness by inducible cAMP early repressor (ICER). J. Leukoc. Biol. 2001. 69: 1053-1059.
-
(2001)
J. Leukoc. Biol.
, vol.69
, pp. 1053-1059
-
-
Bodor, J.1
Feigenbaum, L.2
Bodorova, J.3
Bare, C.4
Reitz, M.S.5
Gress, R.E.6
-
34
-
-
77954166341
-
Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice
-
Lahl, K., Mayer, C. T., Bopp, T., Huehn, J., Loddenkemper, C., Eberl, G., Wirnsberger, G. et al., Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice. J. Immunol. 2009. 183: 5662-5672.
-
(2009)
J. Immunol.
, vol.183
, pp. 5662-5672
-
-
Lahl, K.1
Mayer, C.T.2
Bopp, T.3
Huehn, J.4
Loddenkemper, C.5
Eberl, G.6
Wirnsberger, G.7
-
35
-
-
33846423147
-
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
-
Lahl, K., Loddenkemper, C., Drouin, C., Freyer, J., Arnason, J., Eberl, G., Hamann, A. et al., Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J. Exp. Med. 2007. 204: 57-63.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 57-63
-
-
Lahl, K.1
Loddenkemper, C.2
Drouin, C.3
Freyer, J.4
Arnason, J.5
Eberl, G.6
Hamann, A.7
-
36
-
-
84864279250
-
Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice
-
Gogishvili, T., Langenhorst, D., Lühder, F., Elias, F., Elflein, K., Dennehy, K. M., Gold, R. et al., Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice. PLoS One 2009. 4: e4643.
-
(2009)
PLoS One
, vol.4
-
-
Gogishvili, T.1
Langenhorst, D.2
Lühder, F.3
Elias, F.4
Elflein, K.5
Dennehy, K.M.6
Gold, R.7
-
37
-
-
0035929676
-
Mitogen-activated protein kinase phosphorylates and targets inducible cAMP early repressor to ubiquitin-mediated destruction
-
Yehia, G., Schlotter, F., Razavi, R., Alessandrini, A. and Molina, C. A., Mitogen-activated protein kinase phosphorylates and targets inducible cAMP early repressor to ubiquitin-mediated destruction. J. Biol. Chem. 2001. 276: 35272-35279.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35272-35279
-
-
Yehia, G.1
Schlotter, F.2
Razavi, R.3
Alessandrini, A.4
Molina, C.A.5
-
38
-
-
80052619768
-
Evidence that phosphorylation by the mitotic kinase Cdk1 promotes ICER monoubiquitination and nuclear delocalization
-
Memin, E., Genzale, M., Crow, M. and Molina, C. A. Evidence that phosphorylation by the mitotic kinase Cdk1 promotes ICER monoubiquitination and nuclear delocalization. Exp. Cell. Res. 2011. 317: 2490-2502.
-
(2011)
Exp. Cell. Res.
, vol.317
, pp. 2490-2502
-
-
Memin, E.1
Genzale, M.2
Crow, M.3
Molina, C.A.4
-
39
-
-
6344233216
-
TCR-and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling 1
-
Abrahamsen, H., Baillie, G., Ngai, J., Vang, T., Nika, K., Ruppelt, A., Mustelin, T. et al., TCR-and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling 1. J. Immunol. 2004. 173: 4847-4858.
-
(2004)
J. Immunol.
, vol.173
, pp. 4847-4858
-
-
Abrahamsen, H.1
Baillie, G.2
Ngai, J.3
Vang, T.4
Nika, K.5
Ruppelt, A.6
Mustelin, T.7
-
40
-
-
84856574460
-
Repression of cyclic adenosine monophosphate upregulation disarms and expands human regulatory T cells
-
Klein, M., Vaeth, M., Scheel, T., Grabbe, S., Baumgrass, R., Berberich-Siebelt, F., Bopp, T. et al., Repression of cyclic adenosine monophosphate upregulation disarms and expands human regulatory T cells. J. Immunol. 2012. 188: 1091-1097.
-
(2012)
J. Immunol.
, vol.188
, pp. 1091-1097
-
-
Klein, M.1
Vaeth, M.2
Scheel, T.3
Grabbe, S.4
Baumgrass, R.5
Berberich-Siebelt, F.6
Bopp, T.7
-
42
-
-
33746228122
-
FOXP3 controls regulatory T cell function through cooperation with NFAT
-
Wu, Y., Borde, M., Heissmeyer, V., Feuerer, M., Lapan, A. D., Stroud, J. C., Bates, D. L. et al., FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 2006. 126: 375-387.
-
(2006)
Cell
, vol.126
, pp. 375-387
-
-
Wu, Y.1
Borde, M.2
Heissmeyer, V.3
Feuerer, M.4
Lapan, A.D.5
Stroud, J.C.6
Bates, D.L.7
-
43
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
Hogan, P. G., Chen, L., Nardone, J. and Rao, A., Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 2003. 17: 2205-2232.
-
(2003)
Genes Dev.
, vol.17
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
44
-
-
0032540278
-
Role of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytes
-
Bodor, J. and Habener, J. F., Role of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytes. J. Biol. Chem. 1998. 273: 9544-9551.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9544-9551
-
-
Bodor, J.1
Habener, J.F.2
-
46
-
-
4344718846
-
Cyclic adenosine 5′-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus
-
Kyttaris, V. C., Juang, Y.-T., Tenbrock, K., Weinstein, A. and Tsokos, G. C., Cyclic adenosine 5′-monophosphate response element modulator is responsible for the decreased expression of c-fos and activator protein-1 binding in T cells from patients with systemic lupus erythematosus. J. Immunol. 2004. 173: 3557-3563.
-
(2004)
J. Immunol.
, vol.173
, pp. 3557-3563
-
-
Kyttaris, V.C.1
Juang, Y.-T.2
Tenbrock, K.3
Weinstein, A.4
Tsokos, G.C.5
-
47
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
Wing, K., Onishi, Y., Prieto-Martin, P., Yamaguchi, T., Miyara, M., Fehervari, Z., Nomura, T. et al., CTLA-4 control over Foxp3+ regulatory T cell function. Science 2008. 322: 271-275.
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
Nomura, T.7
-
48
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read, S., Malmstrom, V. and Powrie, F., Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. 2000. 192: 295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
49
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
Takahashi, T., Tagami, T., Yamazaki, S., Uede, T., Shimizu, J., Sakaguchi, N., Mak, T. W. et al., Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J. Exp. Med. 2000. 192: 303-310.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
Mak, T.W.7
-
50
-
-
68149155982
-
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
-
Peggs, K. S., Quezada, S. A., Chambers, C. A., Korman, A. J. and Allison, J. P., Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J. Exp. Med. 2009. 206: 1717-1725.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1717-1725
-
-
Peggs, K.S.1
Quezada, S.A.2
Chambers, C.A.3
Korman, A.J.4
Allison, J.P.5
-
51
-
-
3142708571
-
Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
-
Paust, S., Lu, L., McCarty, N. and Cantor, H., Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease. Proc. Natl. Acad. Sci. U.S.A. 2004. 101: 10398-10403.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10398-10403
-
-
Paust, S.1
Lu, L.2
McCarty, N.3
Cantor, H.4
-
52
-
-
16244390854
-
Regulatory T cells and autoimmune disease
-
Paust, S. and Cantor, H., Regulatory T cells and autoimmune disease. Immunol. Rev. 2005. 204: 195-207.
-
(2005)
Immunol. Rev.
, vol.204
, pp. 195-207
-
-
Paust, S.1
Cantor, H.2
-
53
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
Tang, Q., Adams, J. Y., Tooley, A. J., Bi, M., Fife, B. T., Serra, P., Santamaria, P. et al., Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat. Immunol. 2006. 7: 83-92.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 83-92
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
Bi, M.4
Fife, B.T.5
Serra, P.6
Santamaria, P.7
-
54
-
-
0346119234
-
Modulation of tryptophan catabolism by regulatory T cells
-
Fallarino, F., Grohmann, U., Hwang, K. W., Orabona, C., Vacca, C., Bianchi, R., Belladonna, M. L. et al., Modulation of tryptophan catabolism by regulatory T cells. Nat. Immunol. 2003. 4: 1206-1212.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1206-1212
-
-
Fallarino, F.1
Grohmann, U.2
Hwang, K.W.3
Orabona, C.4
Vacca, C.5
Bianchi, R.6
Belladonna, M.L.7
-
55
-
-
77957019251
-
Cyclic adenosine monophosphate and IL-10 coordinately contribute to nTreg cell-mediated suppression of dendritic cell activation
-
Fassbender, M., Gerlitzki, B., Ullrich, N., Lupp, C., Klein, M., Radsak, M. P., Schmitt, E. et al., Cyclic adenosine monophosphate and IL-10 coordinately contribute to nTreg cell-mediated suppression of dendritic cell activation. Cell Immunol. 2010. 265: 91-96.
-
(2010)
Cell Immunol.
, vol.265
, pp. 91-96
-
-
Fassbender, M.1
Gerlitzki, B.2
Ullrich, N.3
Lupp, C.4
Klein, M.5
Radsak, M.P.6
Schmitt, E.7
-
56
-
-
64249090036
-
The cyclic AMP response element modulator [1] suppresses CD86 expression and APC function
-
Ahlmann, M., Varga, G., Sturm, K., Lippe, R., Benedyk, K., Viemann, D., Scholzen, T. et al., The cyclic AMP response element modulator [1] suppresses CD86 expression and APC function. J. Immunol. 2009. 182: 4167-4174.
-
(2009)
J. Immunol.
, vol.182
, pp. 4167-4174
-
-
Ahlmann, M.1
Varga, G.2
Sturm, K.3
Lippe, R.4
Benedyk, K.5
Viemann, D.6
Scholzen, T.7
-
57
-
-
79955529454
-
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4
-
Qureshi, O. S., Zheng, Y., Nakamura, K., Attridge, K., Manzotti, C., Schmidt, E. M., Baker, J. et al., Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science 2011. 332: 600-603.
-
(2011)
Science
, vol.332
, pp. 600-603
-
-
Qureshi, O.S.1
Zheng, Y.2
Nakamura, K.3
Attridge, K.4
Manzotti, C.5
Schmidt, E.M.6
Baker, J.7
-
58
-
-
80053078419
-
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation
-
Mendoza-Naranjo, A., Bouma, G., Pereda, C., Ramirez, M., Webb, K. F., Tittarelli, A., Lopez, M. N. et al. Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation. J. Immunol. 2011. 187: 3121-3132.
-
(2011)
J. Immunol.
, vol.187
, pp. 3121-3132
-
-
Mendoza-Naranjo, A.1
Bouma, G.2
Pereda, C.3
Ramirez, M.4
Webb, K.F.5
Tittarelli, A.6
Lopez, M.N.7
-
59
-
-
65349151316
-
Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells
-
Bour-Jordan, H. and Bluestone, J. A., Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells. Immunol. Rev. 2009. 229: 41-66.
-
(2009)
Immunol. Rev.
, vol.229
, pp. 41-66
-
-
Bour-Jordan, H.1
Bluestone, J.A.2
-
60
-
-
13944260538
-
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
-
Tai, X., Cowan, M., Feigenbaum, L. and Singer, A., CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. Nat. Immunol. 2005. 6: 152-162.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 152-162
-
-
Tai, X.1
Cowan, M.2
Feigenbaum, L.3
Singer, A.4
-
61
-
-
4544241811
-
Tolerance, not immunity, crucially depends on IL-2
-
Malek, T. R. and Bayer, A. L., Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. 2004. 4: 665-674.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 665-674
-
-
Malek, T.R.1
Bayer, A.L.2
-
62
-
-
23744517125
-
Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis
-
Beyersdorf, N., Gaupp, S., Balbach, K., Schmidt, J., Toyka, K. V., Lin, C.-H., Hanke, T. et al., Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. J. Exp. Med. 2005. 202: 445-455.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 445-455
-
-
Beyersdorf, N.1
Gaupp, S.2
Balbach, K.3
Schmidt, J.4
Toyka, K.V.5
Lin, C.-H.6
Hanke, T.7
-
63
-
-
33748416499
-
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412
-
Suntharalingam, G., Perry, M. R., Ward, S., Brett, S. J., Castello-Cortes, A., Brunner, M. D. and Panoskaltsis, N., Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N. Eng. J. Med. 2006. 355: 1018-1028.
-
(2006)
N. Eng. J. Med.
, vol.355
, pp. 1018-1028
-
-
Suntharalingam, G.1
Perry, M.R.2
Ward, S.3
Brett, S.J.4
Castello-Cortes, A.5
Brunner, M.D.6
Panoskaltsis, N.7
-
64
-
-
33750608522
-
Lessons from TGN1412
-
author reply 1570.
-
Hanke, T., Lessons from TGN1412. Lancet 2006. 368: 1569-1570; author reply 1570.
-
(2006)
Lancet
, vol.368
, pp. 1569-1570
-
-
Hanke, T.1
-
65
-
-
77956304908
-
Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells
-
Eastwood, D., Findlay, L., Poole, S., Bird, C., Wadhwa, M., Moore, M., Burns, C. et al., Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells. Br. J. Pharmacol. 2010. 161: 512-526.
-
(2010)
Br. J. Pharmacol.
, vol.161
, pp. 512-526
-
-
Eastwood, D.1
Findlay, L.2
Poole, S.3
Bird, C.4
Wadhwa, M.5
Moore, M.6
Burns, C.7
-
66
-
-
64249083235
-
Inhibition of cAMP degradation improves regulatory T cell-mediated suppression
-
Bopp, T., Dehzad, N., Reuter, S., Klein, M., Ullrich, N., Stassen, M., Schild, H. et al., Inhibition of cAMP degradation improves regulatory T cell-mediated suppression. J. Immunol. 2009. 182: 4017-4024.
-
(2009)
J. Immunol.
, vol.182
, pp. 4017-4024
-
-
Bopp, T.1
Dehzad, N.2
Reuter, S.3
Klein, M.4
Ullrich, N.5
Stassen, M.6
Schild, H.7
-
67
-
-
78751691629
-
Can Treg therapy prevent GVHD?
-
Komanduri, K. V. andChamplin, R. E., Can Treg therapy prevent GVHD? Blood 2011. 117: 751-752.
-
(2011)
Blood
, vol.117
, pp. 751-752
-
-
Komanduri, K.V.1
Champlin, R.E.2
-
68
-
-
25444454359
-
Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors
-
Sitkovsky, M. and Lukashev, D., Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors. Nat. Rev. Immunol. 2005. 5: 712-721.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 712-721
-
-
Sitkovsky, M.1
Lukashev, D.2
-
69
-
-
0035575975
-
Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
-
Caldwell, C. C., Kojima, H., Lukashev, D., Armstrong, J., Farber, M., Apasov, S. G. and Sitkovsky, M. V., Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions. J. Immunol. 2001. 167: 6140-6149.
-
(2001)
J. Immunol.
, vol.167
, pp. 6140-6149
-
-
Caldwell, C.C.1
Kojima, H.2
Lukashev, D.3
Armstrong, J.4
Farber, M.5
Apasov, S.G.6
Sitkovsky, M.V.7
-
70
-
-
61349158530
-
T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
-
Sitkovsky, M. V., T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response. Trends Immunol. 2009. 30: 102-108.
-
(2009)
Trends Immunol.
, vol.30
, pp. 102-108
-
-
Sitkovsky, M.V.1
-
71
-
-
33750832563
-
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine
-
Kobie, J. J., Shah, P. R., Yang, L., Rebhahn, J. A., Fowell, D. J. and Mosmann, T. R., T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine. J. Immunol. 2006. 177: 6780-6786.
-
(2006)
J. Immunol.
, vol.177
, pp. 6780-6786
-
-
Kobie, J.J.1
Shah, P.R.2
Yang, L.3
Rebhahn, J.A.4
Fowell, D.J.5
Mosmann, T.R.6
-
72
-
-
34250351459
-
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
-
Deaglio, S., Dwyer, K. M., Gao, W., Friedman, D., Usheva, A., Erat, A., Chen, J. F. et al., Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J. Exp. Med. 2007. 204: 1257-1265.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1257-1265
-
-
Deaglio, S.1
Dwyer, K.M.2
Gao, W.3
Friedman, D.4
Usheva, A.5
Erat, A.6
Chen, J.F.7
-
73
-
-
79960418125
-
Connexin 43 signaling enhances the generation of Foxp3+ regulatory T cells
-
Kuczma, M., Lee, J. R. and Kraj, P., Connexin 43 signaling enhances the generation of Foxp3+ regulatory T cells. J. Immunol. 2011. 187: 248-257.
-
(2011)
J. Immunol.
, vol.187
, pp. 248-257
-
-
Kuczma, M.1
Lee, J.R.2
Kraj, P.3
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