-
3
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
Hogan, P. G., L. Chen, J. Nardone, and A. Rao. 2003. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev. 17: 2205-2232.
-
(2003)
Genes Dev.
, vol.17
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
4
-
-
0036234543
-
NFAT signaling: Choreographing the social lives of cells
-
Crabtree, G. R., and E. N. Olson. 2002. NFAT signaling: choreographing the social lives of cells. Cell 109: S67-S79.
-
(2002)
Cell
, vol.109
-
-
Crabtree, G.R.1
Olson, E.N.2
-
5
-
-
0034693087
-
The role of NF-AT transcription factors in T cell activation and differentiation
-
Serfling, E., F. Berberich-Siebelt, S. Chuvpilo, E. Jankevics, S. Klein-Hessling, T. Twardzik, and A. Avots. 2000. The role of NF-AT transcription factors in T cell activation and differentiation. Biochim. Biophys. Acta 1498: 1-18.
-
(2000)
Biochim. Biophys. Acta
, vol.1498
, pp. 1-18
-
-
Serfling, E.1
Berberich-Siebelt, F.2
Chuvpilo, S.3
Jankevics, E.4
Klein-Hessling, S.5
Twardzik, T.6
Avots, A.7
-
6
-
-
18444365894
-
Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis
-
Chuvpilo, S., E. Jankevics, D. Tyrsin, A. Akimzhanov, D. Moroz, M. K. Jha, J. Schulze-Luehrmann, B. Santner-Nanan, E. Feoktistova, T. König, et al. 2002. Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis. Immunity 16: 881-895.
-
(2002)
Immunity
, vol.16
, pp. 881-895
-
-
Chuvpilo, S.1
Jankevics, E.2
Tyrsin, D.3
Akimzhanov, A.4
Moroz, D.5
Jha, M.K.6
Schulze-Luehrmann, J.7
Santner-Nanan, B.8
Feoktistova, E.9
König, T.10
-
7
-
-
67449102913
-
Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin- 2 repression by histone deacetylase
-
Nayak, A., J. Glöckner-Pagel, M. Vaeth, J. E. Schumann, M. Buttmann, T. Bopp, E. Schmitt, E. Serfling, and F. Berberich-Siebelt. 2009. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin- 2 repression by histone deacetylase. J. Biol. Chem. 284: 10935-10946.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 10935-10946
-
-
Nayak, A.1
Glöckner-Pagel, J.2
Vaeth, M.3
Schumann, J.E.4
Buttmann, M.5
Bopp, T.6
Schmitt, E.7
Serfling, E.8
Berberich-Siebelt, F.9
-
8
-
-
3142544806
-
Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1
-
Terui, Y., N. Saad, S. Jia, F. McKeon, and J. Yuan. 2004. Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1. J. Biol. Chem. 279: 28257-28265.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28257-28265
-
-
Terui, Y.1
Saad, N.2
Jia, S.3
McKeon, F.4
Yuan, J.5
-
9
-
-
0029767664
-
Hepatic specification of the gut endoderm in vitro: Cell signaling and transcriptional control
-
Gualdi, R., P. Bossard, M. Zheng, Y. Hamada, J. R. Coleman, and K. S. Zaret. 1996. Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control. Genes Dev. 10: 1670-1682.
-
(1996)
Genes Dev.
, vol.10
, pp. 1670-1682
-
-
Gualdi, R.1
Bossard, P.2
Zheng, M.3
Hamada, Y.4
Coleman, J.R.5
Zaret, K.S.6
-
10
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti, S., I. Barozzi, F. Mietton, S. Polletti, F. De Santa, E. Venturini, L. Gregory, L. Lonie, A. Chew, C. L. Wei, et al. 2010. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32: 317-328.
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
Barozzi, I.2
Mietton, F.3
Polletti, S.4
De Santa, F.5
Venturini, E.6
Gregory, L.7
Lonie, L.8
Chew, A.9
Wei, C.L.10
-
11
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
-
Wei, G., L. Wei, J. Zhu, C. Zang, J. Hu-Li, Z. Yao, K. Cui, Y. Kanno, T. Y. Roh, W. T. Watford, et al. 2009. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 30: 155-167.
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
Zang, C.4
Hu-Li, J.5
Yao, Z.6
Cui, K.7
Kanno, Y.8
Roh, T.Y.9
Watford, W.T.10
-
12
-
-
0242401835
-
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
-
Gong, S., C. Zheng, M. L. Doughty, K. Losos, N. Didkovsky, U. B. Schambra, N. J. Nowak, A. Joyner, G. Leblanc, M. E. Hatten, and N. Heintz. 2003. A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425: 917-925.
-
(2003)
Nature
, vol.425
, pp. 917-925
-
-
Gong, S.1
Zheng, C.2
Doughty, M.L.3
Losos, K.4
Didkovsky, N.5
Schambra, U.B.6
Nowak, N.J.7
Joyner, A.8
Leblanc, G.9
Hatten, M.E.10
Heintz, N.11
-
13
-
-
0030842624
-
Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome
-
Yang, X. W., P. Model, and N. Heintz. 1997. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nat. Biotechnol. 15: 859-865.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 859-865
-
-
Yang, X.W.1
Model, P.2
Heintz, N.3
-
14
-
-
79955731369
-
NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network
-
Bhattacharyya, S., J. Deb, A. K. Patra, D. A. Thuy Pham, W. Chen, M. Vaeth, F. Berberich-Siebelt, S. Klein-Hessling, E. D. Lamperti, K. Reifenberg, et al. 2011. NFATc1 affects mouse splenic B cell function by controlling the calcineurin-NFAT signaling network. J. Exp. Med. 208: 823-839.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 823-839
-
-
Bhattacharyya, S.1
Deb, J.2
Patra, A.K.3
Thuy Pham, D.A.4
Chen, W.5
Vaeth, M.6
Berberich-Siebelt, F.7
Klein-Hessling, S.8
Lamperti, E.D.9
Reifenberg, K.10
-
15
-
-
33748454137
-
NFATc1 autoregulation: A crucial step for cell-fate determination
-
Serfling, E., S. Chuvpilo, J. Liu, T. Höfer, and A. Palmetshofer. 2006. NFATc1 autoregulation: a crucial step for cell-fate determination. Trends Immunol. 27: 461-469.
-
(2006)
Trends Immunol.
, vol.27
, pp. 461-469
-
-
Serfling, E.1
Chuvpilo, S.2
Liu, J.3
Höfer, T.4
Palmetshofer, A.5
-
16
-
-
84872685452
-
An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development
-
DOI: 10.1038/ni.2507
-
Patra, A. K., A. Avots, R. P. Zahedi, T. Schuler, A. Sickmann, U. Bommhardt, and E. Serfling. 2012. An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development. Nat. Immunol. DOI: 10.1038/ni.2507.
-
(2012)
Nat. Immunol.
-
-
Patra, A.K.1
Avots, A.2
Zahedi, R.P.3
Schuler, T.4
Sickmann, A.5
Bommhardt, U.6
Serfling, E.7
-
17
-
-
38349095578
-
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
-
Tone, Y., K. Furuuchi, Y. Kojima, M. L. Tykocinski, M. I. Greene, and M. Tone. 2008. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat. Immunol. 9: 194-202.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 194-202
-
-
Tone, Y.1
Furuuchi, K.2
Kojima, Y.3
Tykocinski, M.L.4
Greene, M.I.5
Tone, M.6
-
18
-
-
0033564299
-
Multiple NF-ATc isoforms with individual transcriptional properties are synthesized in T lymphocytes
-
Chuvpilo, S., A. Avots, F. Berberich-Siebelt, J. Glöckner, C. Fischer, A. Kerstan, C. Escher, I. Inashkina, F. Hlubek, E. Jankevics, et al. 1999. Multiple NF-ATc isoforms with individual transcriptional properties are synthesized in T lymphocytes. J. Immunol. 162: 7294-7301.
-
(1999)
J. Immunol.
, vol.162
, pp. 7294-7301
-
-
Chuvpilo, S.1
Avots, A.2
Berberich-Siebelt, F.3
Glöckner, J.4
Fischer, C.5
Kerstan, A.6
Escher, C.7
Inashkina, I.8
Hlubek, F.9
Jankevics, E.10
-
19
-
-
33751239778
-
Re-evaluating cell-cycle regulation by E2Fs
-
Rowland, B. D., and R. Bernards. 2006. Re-evaluating cell-cycle regulation by E2Fs. Cell 127: 871-874.
-
(2006)
Cell
, vol.127
, pp. 871-874
-
-
Rowland, B.D.1
Bernards, R.2
-
20
-
-
42649120075
-
Regulation and functions of Blimp-1 in T and B lymphocytes
-
Martins, G., and K. Calame. 2008. Regulation and functions of Blimp-1 in T and B lymphocytes. Annu. Rev. Immunol. 26: 133-169.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 133-169
-
-
Martins, G.1
Calame, K.2
-
21
-
-
0029012409
-
Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells
-
Fruman, D. A., S. Y. Pai, S. J. Burakoff, and B. E. Bierer. 1995. Characterization of a mutant calcineurin A alpha gene expressed by EL4 lymphoma cells. Mol. Cell. Biol. 15: 3857-3863.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3857-3863
-
-
Fruman, D.A.1
Pai, S.Y.2
Burakoff, S.J.3
Bierer, B.E.4
-
22
-
-
38749141374
-
Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling
-
Akimzhanov, A., L. Krenacs, T. Schlegel, S. Klein-Hessling, E. Bagdi, E. Stelkovics, E. Kondo, S. Chuvpilo, P. Wilke, A. Avots, et al. 2008. Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling. Am. J. Pathol. 172: 215-224.
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 215-224
-
-
Akimzhanov, A.1
Krenacs, L.2
Schlegel, T.3
Klein-Hessling, S.4
Bagdi, E.5
Stelkovics, E.6
Kondo, E.7
Chuvpilo, S.8
Wilke, P.9
Avots, A.10
-
23
-
-
0027714991
-
Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter
-
Chuvpilo, S., C. Schomberg, R. Gerwig, A. Heinfling, R. Reeves, F. Grummt, and E. Serfling. 1993. Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter. Nucleic Acids Res. 21: 5694-5704.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 5694-5704
-
-
Chuvpilo, S.1
Schomberg, C.2
Gerwig, R.3
Heinfling, A.4
Reeves, R.5
Grummt, F.6
Serfling, E.7
-
24
-
-
0028229065
-
Calcineurin mediates human tumor necrosis factor alpha gene induction in stimulated T and B cells
-
Goldfeld, A. E., E. Tsai, R. Kincaid, P. J. Belshaw, S. L. Schrieber, J. L. Strominger, and A. Rao. 1994. Calcineurin mediates human tumor necrosis factor alpha gene induction in stimulated T and B cells. J. Exp. Med. 180: 763-768.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 763-768
-
-
Goldfeld, A.E.1
Tsai, E.2
Kincaid, R.3
Belshaw, P.J.4
Schrieber, S.L.5
Strominger, J.L.6
Rao, A.7
-
25
-
-
0034663805
-
Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis
-
Youn, H. D., T. A. Chatila, and J. O. Liu. 2000. Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis. EMBO J. 19: 4323-4331.
-
(2000)
EMBO J.
, vol.19
, pp. 4323-4331
-
-
Youn, H.D.1
Chatila, T.A.2
Liu, J.O.3
-
26
-
-
42449121864
-
NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells
-
Ullerås, E., M. Karlberg, C. Mö ller Westerberg, J. Alfredsson, S. Gerondakis, A. Strasser, and G. Nilsson. 2008. NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells. Blood 111: 3081-3089.
-
(2008)
Blood
, vol.111
, pp. 3081-3089
-
-
Ullerås, E.1
Karlberg, M.2
Möller Westerberg, C.3
Alfredsson, J.4
Gerondakis, S.5
Strasser, A.6
Nilsson, G.7
-
27
-
-
0037155830
-
Regulation of the murine Nfatc1 gene by NFATc2
-
Zhou, B., R. Q. Cron, B. Wu, A. Genin, Z. Wang, S. Liu, P. Robson, and H. S. Baldwin. 2002. Regulation of the murine Nfatc1 gene by NFATc2. J. Biol. Chem. 277: 10704-10711.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10704-10711
-
-
Zhou, B.1
Cron, R.Q.2
Wu, B.3
Genin, A.4
Wang, Z.5
Liu, S.6
Robson, P.7
Baldwin, H.S.8
-
28
-
-
17044439536
-
B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice
-
Samanta, D. N., A. Palmetshofer, D. Marinkovic, T. Wirth, E. Serfling, and L. Nitschke. 2005. B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice. J. Immunol. 174: 4797-4802.
-
(2005)
J. Immunol.
, vol.174
, pp. 4797-4802
-
-
Samanta, D.N.1
Palmetshofer, A.2
Marinkovic, D.3
Wirth, T.4
Serfling, E.5
Nitschke, L.6
-
29
-
-
0034129629
-
Signaling and transcription in T helper development
-
Murphy, K. M., W. Ouyang, J. D. Farrar, J. Yang, S. Ranganath, H. Asnagli, M. Afkarian, and T. L. Murphy. 2000. Signaling and transcription in T helper development. Annu. Rev. Immunol. 18: 451-494.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 451-494
-
-
Murphy, K.M.1
Ouyang, W.2
Farrar, J.D.3
Yang, J.4
Ranganath, S.5
Asnagli, H.6
Afkarian, M.7
Murphy, T.L.8
-
30
-
-
0036305450
-
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
Avni, O., D. Lee, F. Macian, S. J. Szabo, L. H. Glimcher, and A. Rao. 2002. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat. Immunol. 3: 643-651.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 643-651
-
-
Avni, O.1
Lee, D.2
MacIan, F.3
Szabo, S.J.4
Glimcher, L.H.5
Rao, A.6
-
31
-
-
77957940722
-
The NIH roadmap epigenomics mapping consortium
-
Bernstein, B. E., J. A. Stamatoyannopoulos, J. F. Costello, B. Ren, A. Milosavljevic, A. Meissner, M. Kellis, M. A. Marra, A. L. Beaudet, J. R. Ecker, et al. 2010. The NIH Roadmap Epigenomics Mapping Consortium. Nat. Biotechnol. 28: 1045-1048.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 1045-1048
-
-
Bernstein, B.E.1
Stamatoyannopoulos, J.A.2
Costello, J.F.3
Ren, B.4
Milosavljevic, A.5
Meissner, A.6
Kellis, M.7
Marra, M.A.8
Beaudet, A.L.9
Ecker, J.R.10
-
32
-
-
0037179716
-
Active genes are tri-methylated at K4 of histone H3
-
Santos-Rosa, H., R. Schneider, A. J. Bannister, J. Sherriff, B. E. Bernstein, N. C. Emre, S. L. Schreiber, J. Mellor, and T. Kouzarides. 2002. Active genes are tri-methylated at K4 of histone H3. Nature 419: 407-411.
-
(2002)
Nature
, vol.419
, pp. 407-411
-
-
Santos-Rosa, H.1
Schneider, R.2
Bannister, A.J.3
Sherriff, J.4
Bernstein, B.E.5
Emre, N.C.6
Schreiber, S.L.7
Mellor, J.8
Kouzarides, T.9
-
33
-
-
33746256850
-
Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression
-
Rasheed, A. U., H. P. Rahn, F. Sallusto, M. Lipp, and G. Mü ller. 2006. Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expression. Eur. J. Immunol. 36: 1892-1903.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 1892-1903
-
-
Rasheed, A.U.1
Rahn, H.P.2
Sallusto, F.3
Lipp, M.4
Müller, G.5
-
34
-
-
67649669255
-
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
-
Ramirez-Carrozzi, V. R., D. Braas, D. M. Bhatt, C. S. Cheng, C. Hong, K. R. Doty, J. C. Black, A. Hoffmann, M. Carey, and S. T. Smale. 2009. A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell 138: 114-128.
-
(2009)
Cell
, vol.138
, pp. 114-128
-
-
Ramirez-Carrozzi, V.R.1
Braas, D.2
Bhatt, D.M.3
Cheng, C.S.4
Hong, C.5
Doty, K.R.6
Black, J.C.7
Hoffmann, A.8
Carey, M.9
Smale, S.T.10
-
35
-
-
80555135917
-
Regulation of primary response genes
-
Fowler, T., R. Sen, and A. L. Roy. 2011. Regulation of primary response genes. Mol. Cell 44: 348-360.
-
(2011)
Mol. Cell
, vol.44
, pp. 348-360
-
-
Fowler, T.1
Sen, R.2
Roy, A.L.3
-
36
-
-
84857052421
-
Transcriptional regulation in the innate immune system
-
Smale, S. T. 2012. Transcriptional regulation in the innate immune system. Curr. Opin. Immunol. 24: 51-57.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 51-57
-
-
Smale, S.T.1
-
37
-
-
84864251757
-
Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions
-
Bhatt, D. M., A. Pandya-Jones, A. J. Tong, I. Barozzi, M. M. Lissner, G. Natoli, D. L. Black, and S. T. Smale. 2012. Transcript dynamics of proinflammatory genes revealed by sequence analysis of subcellular RNA fractions. Cell 150: 279-290.
-
(2012)
Cell
, vol.150
, pp. 279-290
-
-
Bhatt, D.M.1
Pandya-Jones, A.2
Tong, A.J.3
Barozzi, I.4
Lissner, M.M.5
Natoli, G.6
Black, D.L.7
Smale, S.T.8
-
38
-
-
33846228444
-
Antigen-receptor signaling to nuclear factor kappa B
-
Schulze-Luehrmann, J., and S. Ghosh. 2006. Antigen-receptor signaling to nuclear factor kappa B. Immunity 25: 701-715.
-
(2006)
Immunity
, vol.25
, pp. 701-715
-
-
Schulze-Luehrmann, J.1
Ghosh, S.2
|