The flavonoid-enriched fraction AF4 suppresses neuroinflammation and promotes restorative gene expression in a mouse model of experimental autoimmune encephalomyelitis

Journal of Neuroimmunology

Volumn 268, Issue 1-2, 2014, Pages 71-83

  Warford, Jordan ^a   Jones, Quinton R D ^a   Nichols, Matthew ^a   Sullivan, Victoria ^a   Rupasinghe, H P Vasantha ^b   Robertson, George S ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Chemokine; Cytokine; Multiple sclerosis; Polyphenolic; Remyelination

Indexed keywords

ACYL COENZYME A DESATURASE 1; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; CXCL9 CHEMOKINE; HERBACEOUS AGENT; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELIN BASIC PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; QUERCETIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CEREBELLUM DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; EXPERIMENTAL MODEL; FEMALE; GENE EXPRESSION; GLIOSIS; MBP GENE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PGC 1ALPHA GENE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REMYELINIZATION; SCD 1 GENE; SIGNAL TRANSDUCTION; SPINAL CORD DISEASE;

CHEMOKINE; CYTOKINE; MULTIPLE SCLEROSIS; POLYPHENOLIC; REMYELINATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRAIN; CHROMATOGRAPHY, LIQUID; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLAVONOIDS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALUS; MICE; MICE, INBRED C57BL; PLANT EXTRACTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPINAL CORD; TANDEM MASS SPECTROMETRY;

EID: 84896730154     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2014.01.007     Document Type: Article

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