Epimedium flavonoids ameliorate experimental autoimmune encephalomyelitis in rats by modulating neuroinflammatory and neurotrophic responses

Neuropharmacology

Volumn 63, Issue 5, 2012, Pages 851-862

  Yin, Lin Lin ^a   Lin, Li Li ^a   Zhang, Lan ^a   Li, Lin ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Epimedium flavonoids; Experimental autoimmune encephalomyelitis; Multiple sclerosis; Myelination; Neuroinflammation; Neurotrophin

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; FLAVONOID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MYELIN BASIC PROTEIN; NERVE GROWTH FACTOR; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; DRUG EFFECT; EPIMEDIUM; EPIMEDIUM SAGITTATUM; FEMALE; GUINEA PIG; INFLAMMATION; INFLAMMATORY INFILTRATE; MYELIN SHEATH; NERVE FIBER; NEUROTROPISM; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASTROCYTES; AXONS; CENTRAL NERVOUS SYSTEM; DEMYELINATING DISEASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EPIMEDIUM; FEMALE; FLAVONOIDS; MYELIN SHEATH; NERVE GROWTH FACTORS; NEUROIMMUNOMODULATION; OLIGODENDROGLIA; RANDOM ALLOCATION; RATS; RATS, INBRED LEW; SEVERITY OF ILLNESS INDEX; SPINAL CORD; T-LYMPHOCYTES;

EID: 84864484217     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.06.025     Document Type: Article

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