NF-κB enhances hypoxia-driven T-cell immunosuppression via upregulation of adenosine A2A receptors

Cellular Signalling

Volumn 26, Issue 5, 2014, Pages 1060-1067

  Bruzzese, Laurie ^a   Fromonot, Julien ^a   By, Youlet ^a   Durand Gorde, Josée Martine ^a   Condo, Jocelyne ^a   Kipson, Nathalie ^a   Guieu, Régis ^a   Fenouillet, Emmanuel ^a,b   Ruf, Jean ^a,c  

^a AIX MARSEILLE UNIVERSITY   (France)

^b CNRS   (France)

^c INSERM   (France)

Author keywords

Adenosine; Adenosine A2A receptor; Cell viability; Chemical hypoxia; Hydrogen sulfide

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 4 [2 [7 AMINO 2 (2 FURYL) 1,2,4 TRIAZOLO[2,3 A][1,3,5]TRIAZIN 5 YLAMINO]ETHYL]PHENOL; 8 BROMO CYCLIC GMP; ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE DEAMINASE; CELL PROTEIN; COBALT CHLORIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHODIESTERASE IV; PHYTOHEMAGGLUTININ; PROTEIN H2S; ROLIPRAM; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; HYDROGEN SULFIDE; PHORBOL 13 ACETATE 12 MYRISTATE;

ARTICLE; CELL HYPOXIA; CELL PROTECTION; CELL STIMULATION; CELL VIABILITY; DOWN REGULATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HYPOXIC CELL; IMMUNOMODULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; CD4+ T LYMPHOCYTE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; INFLAMMATION; PERIPHERAL LYMPHOCYTE; T LYMPHOCYTE;

ADENOSINE; ADENOSINE A(2A) RECEPTOR; CELL VIABILITY; CHEMICAL HYPOXIA; HYDROGEN SULFIDE;

ADENOSINE A2 RECEPTOR AGONISTS; ADENOSINE A2 RECEPTOR ANTAGONISTS; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; COBALT; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOSUPPRESSION; ISOQUINOLINES; NF-KAPPA B; RECEPTOR, ADENOSINE A2A; SIGNAL TRANSDUCTION; SULFITES; SULFONAMIDES; T-LYMPHOCYTES; TRIAZINES; TRIAZOLES; UP-REGULATION;

EID: 84896708815     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.01.024     Document Type: Article

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