-
1
-
-
0036359548
-
Hypoxia-a key regulatory factor in tumour growth
-
Harris AL (2002) Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
2
-
-
19544391973
-
The 'danger' sensors that STOP the immune response: the A2 adenosine receptors?
-
Sitkovsky MV, Ohta A (2005) The 'danger' sensors that STOP the immune response: the A2 adenosine receptors? Trends Immunol 26: 299-304.
-
(2005)
Trends Immunol
, vol.26
, pp. 299-304
-
-
Sitkovsky, M.V.1
Ohta, A.2
-
3
-
-
22144483402
-
Control of adenosine transport by hypoxia
-
Gorlach A (2005) Control of adenosine transport by hypoxia. Circ Res 97: 1-3.
-
(2005)
Circ Res
, vol.97
, pp. 1-3
-
-
Gorlach, A.1
-
4
-
-
0035209620
-
International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
-
Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J (2001) International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53: 527-552.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 527-552
-
-
Fredholm, B.B.1
IJzerman, A.P.2
Jacobson, K.A.3
Klotz, K.N.4
Linden, J.5
-
5
-
-
25444454359
-
Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors
-
Sitkovsky M, Lukashev D (2005) Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors. Nat Rev Immunol 5: 712-721.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 712-721
-
-
Sitkovsky, M.1
Lukashev, D.2
-
6
-
-
68849095740
-
The adenosinergic immunomodulatory drugs
-
Ohta A, Sitkovsky M (2009) The adenosinergic immunomodulatory drugs. Curr Opin Pharmacol 9: 501-506.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 501-506
-
-
Ohta, A.1
Sitkovsky, M.2
-
7
-
-
0033954723
-
Chronic hypoxia enhances adenosine release in rat PC12 cells by altering adenosine metabolism and membrane transport
-
Kobayashi S, Zimmermann H, Millhorn DE (2000) Chronic hypoxia enhances adenosine release in rat PC12 cells by altering adenosine metabolism and membrane transport. J Neurochem 74: 621-632.
-
(2000)
J Neurochem
, vol.74
, pp. 621-632
-
-
Kobayashi, S.1
Zimmermann, H.2
Millhorn, D.E.3
-
8
-
-
34250351459
-
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
-
Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC (2007) Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 204: 1257-1265.
-
(2007)
J Exp Med
, vol.204
, pp. 1257-1265
-
-
Deaglio, S.1
Dwyer, K.M.2
Gao, W.3
Friedman, D.4
Usheva, A.5
Erat, A.6
Chen, J.F.7
Enjyoji, K.8
Linden, J.9
Oukka, M.10
Kuchroo, V.K.11
Strom, T.B.12
Robson, S.C.13
-
9
-
-
77957751748
-
Monoclonal antibody-assisted stimulation of adenosine A2A receptors induces simultaneous downregulation of CXCR4 and CCR5 on CD4+ T-cells
-
By Y, Durand-Gorde JM, Condo J, Lejeune PJ, Fenouillet E, Guieu R, Ruf J (2010) Monoclonal antibody-assisted stimulation of adenosine A2A receptors induces simultaneous downregulation of CXCR4 and CCR5 on CD4+ T-cells. Hum Immunol 71: 1073-1076.
-
(2010)
Hum Immunol
, vol.71
, pp. 1073-1076
-
-
By, Y.1
Durand-Gorde, J.M.2
Condo, J.3
Lejeune, P.J.4
Fenouillet, E.5
Guieu, R.6
Ruf, J.7
-
10
-
-
0033065317
-
Development of an HPLC/diode array detector method for the determination of human plasma adenosine concentrations
-
Guieu R, Sampieri F, Bechis G, Halimi G, Dussol B, Berland Y, Sampol J, Rochat H (1999) Development of an HPLC/diode array detector method for the determination of human plasma adenosine concentrations. J Liq Chromatogr 22: 1829-1841.
-
(1999)
J Liq Chromatogr
, vol.22
, pp. 1829-1841
-
-
Guieu, R.1
Sampieri, F.2
Bechis, G.3
Halimi, G.4
Dussol, B.5
Berland, Y.6
Sampol, J.7
Rochat, H.8
-
11
-
-
4644276771
-
Kinetic study of adenosine concentrations and the expression of adenosine deaminase in mononuclear cells during hemodialysis
-
Dussol B, Fenouillet E, Brunet P, Purgus R, Sauze N, Carrega L, Mercier L, Zouher I, Bechis G, Berland Y, Guieu R (2004) Kinetic study of adenosine concentrations and the expression of adenosine deaminase in mononuclear cells during hemodialysis. Kidney Int 66: 1640-1646.
-
(2004)
Kidney Int
, vol.66
, pp. 1640-1646
-
-
Dussol, B.1
Fenouillet, E.2
Brunet, P.3
Purgus, R.4
Sauze, N.5
Carrega, L.6
Mercier, L.7
Zouher, I.8
Bechis, G.9
Berland, Y.10
Guieu, R.11
-
12
-
-
57749106226
-
Production of an agonist-like monoclonal antibody to the human A2A receptor of adenosine for clinical use
-
By Y, Durand-Gorde JM, Condo J, Lejeune PJ, Mallet B, Carayon P, Guieu R, Ruf J (2009) Production of an agonist-like monoclonal antibody to the human A2A receptor of adenosine for clinical use. Mol Immunol 46: 400-405.
-
(2009)
Mol Immunol
, vol.46
, pp. 400-405
-
-
By, Y.1
Durand-Gorde, J.M.2
Condo, J.3
Lejeune, P.J.4
Mallet, B.5
Carayon, P.6
Guieu, R.7
Ruf, J.8
-
13
-
-
34248364002
-
Importance of culturing primary lymphocytes at physiological oxygen levels
-
Atkuri KR, Herzenberg LA, Niemi AK, Cowan T, Herzenberg LA (2007) Importance of culturing primary lymphocytes at physiological oxygen levels. Proc Natl Acad Sci U S A 104: 4547-4552.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4547-4552
-
-
Atkuri, K.R.1
Herzenberg, L.A.2
Niemi, A.K.3
Cowan, T.4
Herzenberg, L.A.5
-
14
-
-
0035575975
-
Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
-
Caldwell CC, Kojima H, Lukashev D, Armstrong J, Farber M, Apasov SG, Sitkovsky MV (2001) Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions. J Immunol 167: 6140-6149.
-
(2001)
J Immunol
, vol.167
, pp. 6140-6149
-
-
Caldwell, C.C.1
Kojima, H.2
Lukashev, D.3
Armstrong, J.4
Farber, M.5
Apasov, S.G.6
Sitkovsky, M.V.7
-
15
-
-
0033525924
-
Oxidative phosphorylation at the fin de siecle
-
Saraste M (1999) Oxidative phosphorylation at the fin de siecle. Science 283: 1488-1493.
-
(1999)
Science
, vol.283
, pp. 1488-1493
-
-
Saraste, M.1
-
16
-
-
0027960973
-
Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production
-
Greiner EF, Guppy M, Brand K (1994) Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production. J Biol Chem 269: 31484-31490.
-
(1994)
J Biol Chem
, vol.269
, pp. 31484-31490
-
-
Greiner, E.F.1
Guppy, M.2
Brand, K.3
-
17
-
-
0017652941
-
Influence of inhibitors of cellular function on chemotactic factor-induced neutrophil aggregation
-
O'Flaherty JT, Kreutzer DL, Showell HJ, Ward PA (1977) Influence of inhibitors of cellular function on chemotactic factor-induced neutrophil aggregation. J Immunol 119: 1751-1756.
-
(1977)
J Immunol
, vol.119
, pp. 1751-1756
-
-
O'Flaherty, J.T.1
Kreutzer, D.L.2
Showell, H.J.3
Ward, P.A.4
-
18
-
-
0018578988
-
Chemotactic factor-induced generation of superoxide radicals by human neutrophils: effect of metabolic inhibitors and antiinflammatory drugs
-
Simchowitz L, Mehta J, Spilberg I (1979) Chemotactic factor-induced generation of superoxide radicals by human neutrophils: effect of metabolic inhibitors and antiinflammatory drugs. Arthritis Rheum 22: 755-763.
-
(1979)
Arthritis Rheum
, vol.22
, pp. 755-763
-
-
Simchowitz, L.1
Mehta, J.2
Spilberg, I.3
-
19
-
-
0017717843
-
Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis
-
MacDonald HR, Koch CJ (1977) Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis. J Exp Med 146: 698-709.
-
(1977)
J Exp Med
, vol.146
, pp. 698-709
-
-
MacDonald, H.R.1
Koch, C.J.2
-
20
-
-
64149086386
-
Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep
-
Maeda T, Koos BJ (2009) Adenosine A1 and A2a receptors modulate insulinemia, glycemia, and lactatemia in fetal sheep. Am J Physiol Regul Integr Comp Physiol 296: R693-R701.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.296
-
-
Maeda, T.1
Koos, B.J.2
-
21
-
-
70349658872
-
Adenosine: an old drug newly discovered
-
Eltzschig HK (2009) Adenosine: an old drug newly discovered. Anesthesiology 111: 904-915.
-
(2009)
Anesthesiology
, vol.111
, pp. 904-915
-
-
Eltzschig, H.K.1
-
22
-
-
47049088629
-
HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak
-
Morote-Garcia JC, Rosenberger P, Kuhlicke J, Eltzschig HK (2008) HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak. Blood 111: 5571-5580.
-
(2008)
Blood
, vol.111
, pp. 5571-5580
-
-
Morote-Garcia, J.C.1
Rosenberger, P.2
Kuhlicke, J.3
Eltzschig, H.K.4
-
23
-
-
0344305461
-
Differential requirement for A2a and A3 adenosine receptors for the protective effect of inosine in vivo
-
Gomez G, Sitkovsky MV (2003) Differential requirement for A2a and A3 adenosine receptors for the protective effect of inosine in vivo. Blood 102: 4472-4478.
-
(2003)
Blood
, vol.102
, pp. 4472-4478
-
-
Gomez, G.1
Sitkovsky, M.V.2
-
24
-
-
33748149076
-
Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26
-
Eltzschig HK, Faigle M, Knapp S, Karhausen J, Ibla J, Rosenberger P, Odegard KC, Laussen PC, Thompson LF, Colgan SP (2006) Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26. Blood 108: 1602-1610.
-
(2006)
Blood
, vol.108
, pp. 1602-1610
-
-
Eltzschig, H.K.1
Faigle, M.2
Knapp, S.3
Karhausen, J.4
Ibla, J.5
Rosenberger, P.6
Odegard, K.C.7
Laussen, P.C.8
Thompson, L.F.9
Colgan, S.P.10
-
25
-
-
0030878807
-
Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion
-
Huang S, Apasov S, Koshiba M, Sitkovsky M (1997) Role of A2a extracellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion. Blood 90: 1600-1610.
-
(1997)
Blood
, vol.90
, pp. 1600-1610
-
-
Huang, S.1
Apasov, S.2
Koshiba, M.3
Sitkovsky, M.4
-
26
-
-
61349158530
-
T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
-
Sitkovsky MV (2009) T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response. Trends Immunol 30: 102-108.
-
(2009)
Trends Immunol
, vol.30
, pp. 102-108
-
-
Sitkovsky, M.V.1
-
27
-
-
0032586888
-
Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies
-
Koshiba M, Rosin DL, Hayashi N, Linden J, Sitkovsky MV (1999) Patterns of A2A extracellular adenosine receptor expression in different functional subsets of human peripheral T cells. Flow cytometry studies with anti-A2A receptor monoclonal antibodies. Mol Pharmacol 55: 614-624.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 614-624
-
-
Koshiba, M.1
Rosin, D.L.2
Hayashi, N.3
Linden, J.4
Sitkovsky, M.V.5
-
28
-
-
51049101334
-
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
-
Hasko G, Linden J, Cronstein B, Pacher P (2008) Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 7: 759-770.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 759-770
-
-
Hasko, G.1
Linden, J.2
Cronstein, B.3
Pacher, P.4
-
29
-
-
0035924320
-
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
-
Ohta A, Sitkovsky M (2001) Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 414: 916-920.
-
(2001)
Nature
, vol.414
, pp. 916-920
-
-
Ohta, A.1
Sitkovsky, M.2
-
30
-
-
41649119553
-
Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway
-
Chouker A, Thiel M, Lukashev D, Ward JM, Kaufmann I, Apasov S, Sitkovsky MV, Ohta A (2008) Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway. Mol Med 14: 116-123.
-
(2008)
Mol Med
, vol.14
, pp. 116-123
-
-
Chouker, A.1
Thiel, M.2
Lukashev, D.3
Ward, J.M.4
Kaufmann, I.5
Apasov, S.6
Sitkovsky, M.V.7
Ohta, A.8
-
31
-
-
22744450934
-
Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury
-
Thiel M, Chouker A, Ohta A, Jackson E, Caldwell C, Smith P, Lukashev D, Bittmann I, Sitkovsky MV (2005) Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury. PLoS Biol 3: e174.
-
(2005)
PLoS Biol
, vol.3
-
-
Thiel, M.1
Chouker, A.2
Ohta, A.3
Jackson, E.4
Caldwell, C.5
Smith, P.6
Lukashev, D.7
Bittmann, I.8
Sitkovsky, M.V.9
-
32
-
-
55249095393
-
Hypoxia controls CD4 + CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha
-
Ben-Shoshan J, Maysel-Auslender S, Mor A, Keren G, George J (2008) Hypoxia controls CD4 + CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1alpha. Eur J Immunol 38: 2412-2418.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2412-2418
-
-
Ben-Shoshan, J.1
Maysel-Auslender, S.2
Mor, A.3
Keren, G.4
George, J.5
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