Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89

Journal of Biological Chemistry

Volumn 271, Issue 42, 1996, Pages 26157-26164

  Engh, Richard A ^a   Girod, Andreas ^b   Kinzel, Volker ^b   Huber, Robert ^a   Bossemeyer, Dirk ^b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN KINASE C INHIBITOR;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; X RAY DIFFRACTION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; BINDING SITES; CASEIN KINASE II; CASEIN KINASES; CATTLE; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; GLYCINE; ISOQUINOLINES; MYOSIN-LIGHT-CHAIN KINASE; PROTEIN CONFORMATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; SULFONAMIDES;

EID: 0029860018     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.42.26157     Document Type: Article

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