Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in hacat cells through inhibition of ROS/NF-κB/COX-2 pathway

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Yang, Chuntao ^a   Yang, Zhanli ^a   Zhang, Meifen ^b   Dong, Qi ^c   Wang, Xiuyu ^a   Lan, Aiping ^a   Zeng, Fanqin ^b   Chen, Peixi ^a   Wang, Chuhuai ^b   Feng, Jianqiang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT CHLORIDE; CYCLOOXYGENASE 2; HYDROGEN SULFIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; SODIUM HYDROSULFIDE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; COBALT; DRUG DERIVATIVE; N-(2-CYCLOHEXYLOXY-4-NITROPHENYL)METHANESULFONAMIDE; NITROBENZENE DERIVATIVE; PROLINE; PROLINEDITHIOCARBAMATE; PROSTAGLANDIN SYNTHASE INHIBITOR; PTGS2 PROTEIN, HUMAN; SULFONAMIDE; THIOCARBAMIC ACID DERIVATIVE;

ARTICLE; CELL HYPOXIA; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFLAMMATION; PROTEIN EXPRESSION; PROTEIN SECRETION; ANOXIA; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANOXIA; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; COBALT; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYDROGEN SULFIDE; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKIN-8; NF-KAPPA B; NITROBENZENES; PROLINE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SULFONAMIDES; THIOCARBAMATES;

EID: 79960320543     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021971     Document Type: Article

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