메뉴 건너뛰기




Volumn 86, Issue 18, 2012, Pages 10211-10217

The NS1 protein of influenza A virus blocks RIG-I-Mediated activation of the noncanonical NF-κB pathway and p52/RelB-dependent gene expression in lung epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; PROTEIN P52; RETINOIC ACID INDUCIBLE PROTEIN I; TRANSCRIPTION FACTOR RELB;

EID: 84866156494     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00323-12     Document Type: Article
Times cited : (61)

References (37)
  • 1
    • 9144275033 scopus 로고    scopus 로고
    • Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers
    • Bonizzi G, et al. 2004. Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers. EMBO J. 23:4202-4210.
    • (2004) EMBO J. , vol.23 , pp. 4202-4210
    • Bonizzi, G.1
  • 2
    • 0037107399 scopus 로고    scopus 로고
    • CD40 regulates the processing of NF-kappaB2 p100 to p52
    • Coope HJ, et al. 2002. CD40 regulates the processing of NF-kappaB2 p100 to p52. EMBO J. 21:5375-5385.
    • (2002) EMBO J. , vol.21 , pp. 5375-5385
    • Coope, H.J.1
  • 3
    • 0032797272 scopus 로고    scopus 로고
    • Chemokines and cell migration in secondary lymphoid organs
    • Cyster JG. 1999. Chemokines and cell migration in secondary lymphoid organs. Science 286:2098-2102.
    • (1999) Science , vol.286 , pp. 2098-2102
    • Cyster, J.G.1
  • 4
    • 33749265867 scopus 로고    scopus 로고
    • The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development
    • Dejardin E. 2006. The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development. Biochem. Pharmacol. 72:1161-1179.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1161-1179
    • Dejardin, E.1
  • 5
    • 0345167006 scopus 로고    scopus 로고
    • A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice
    • Donelan NR, Basler CF, García-Sastre A. 2003. A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice. J. Virol. 77:13257-13266.
    • (2003) J. Virol. , vol.77 , pp. 13257-13266
    • Donelan, N.R.1    Basler, C.F.2    García-Sastre, A.3
  • 6
    • 77954171692 scopus 로고    scopus 로고
    • The alternative NF-kappaB signalling pathway is a prerequisite for an appropriate immune response against lymphocytic choriomeningitis virus infection
    • Droebner K, et al. 2010. The alternative NF-kappaB signalling pathway is a prerequisite for an appropriate immune response against lymphocytic choriomeningitis virus infection. Viral Immunol. 23:295-308.
    • (2010) Viral Immunol. , vol.23 , pp. 295-308
    • Droebner, K.1
  • 7
    • 80051929271 scopus 로고    scopus 로고
    • Expression of duck CCL19 and CCL21 and CCR7 receptor in lymphoid and influenza-infected tissues
    • Fleming-Canepa X, et al. 2011. Expression of duck CCL19 and CCL21 and CCR7 receptor in lymphoid and influenza-infected tissues. Mol. Immunol. 48:1950-1957.
    • (2011) Mol. Immunol. , vol.48 , pp. 1950-1957
    • Fleming-Canepa, X.1
  • 8
    • 0031964855 scopus 로고    scopus 로고
    • Mice deficient in nuclear factor (NF)-κB/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
    • Franzoso G, et al. 1998. Mice deficient in nuclear factor (NF)-κB/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture. J. Exp. Med. 187:147-159.
    • (1998) J. Exp. Med. , vol.187 , pp. 147-159
    • Franzoso, G.1
  • 9
    • 65549164536 scopus 로고    scopus 로고
    • Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I
    • Gack MU, et al. 2009. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe 5:439-449.
    • (2009) Cell Host Microbe. , vol.5 , pp. 439-449
    • Gack, M.U.1
  • 10
    • 0345004816 scopus 로고    scopus 로고
    • Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems
    • García-Sastre A, et al. 1998. Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. Virology 252:324-330.
    • (1998) Virology , vol.252 , pp. 324-330
    • García-Sastre, A.1
  • 11
    • 33847670199 scopus 로고    scopus 로고
    • NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I
    • Guo Z, et al. 2007. NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I. Am. J. Respir. Cell Mol. Biol. 36:263-269.
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.36 , pp. 263-269
    • Guo, Z.1
  • 12
    • 53749106185 scopus 로고    scopus 로고
    • NF-κB signaling differentially regulates influenza virus RNA synthesis
    • Kumar N, Xin Z-T, Liang Y, Ly H, Liang Y. 2008. NF-κB signaling differentially regulates influenza virus RNA synthesis. J. Virol. 82:9880-9889.
    • (2008) J. Virol. , vol.82 , pp. 9880-9889
    • Kumar, N.1    Xin, Z.-T.2    Liang, Y.3    Ly, H.4    Liang, Y.5
  • 13
    • 53149137461 scopus 로고    scopus 로고
    • Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kappa B2 complexes via a novel retinoic acid-inducible gene-I{middle dot}NF-kappa B-inducing kinase signaling pathway
    • Liu P, Li K, Garofalo RP, Brasier AR. 2008. Respiratory syncytial virus induces RelA release from cytoplasmic 100-kDa NF-kappa B2 complexes via a novel retinoic acid-inducible gene-I{middle dot}NF-kappa B-inducing kinase signaling pathway. J. Biol. Chem. 283:23169-23178.
    • (2008) J. Biol. Chem. , vol.283 , pp. 23169-23178
    • Liu, P.1    Li, K.2    Garofalo, R.P.3    Brasier, A.R.4
  • 14
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 15
    • 80052755593 scopus 로고    scopus 로고
    • Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections
    • Ludwig S. 2011. Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections. Biol. Chem. 392:837-847.
    • (2011) Biol. Chem. , vol.392 , pp. 837-847
    • Ludwig, S.1
  • 16
    • 54049111798 scopus 로고    scopus 로고
    • Influenza viruses and the NF-κB signaling pathway-towards a novel concept of antiviral therapy
    • Ludwig S, Planz O. 2008. Influenza viruses and the NF-κB signaling pathway-towards a novel concept of antiviral therapy. Biol. Chem. 389:1307-1312.
    • (2008) Biol. Chem. , vol.389 , pp. 1307-1312
    • Ludwig, S.1    Planz, O.2
  • 17
    • 0035809310 scopus 로고    scopus 로고
    • Essential role of nuclear factor (NF)-κB-inducing kinase and inhibitor of κB (IκB) kinase α in Nf-κB activation through lymphotoxin β receptor, but not through tumor necrosis factor receptor I
    • Matsushima A, et al. 2001. Essential role of nuclear factor (NF)-κB-inducing kinase and inhibitor of κB (IκB) kinase α in Nf-κB activation through lymphotoxin β receptor, but not through tumor necrosis factor receptor I. J. Exp. Med. 193:631-636.
    • (2001) J. Exp. Med. , vol.193 , pp. 631-636
    • Matsushima, A.1
  • 18
    • 34250783318 scopus 로고    scopus 로고
    • Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity
    • Mazur I, et al. 2007. Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity. Cell. Microbiol. 9:1683-1694.
    • (2007) Cell. Microbiol. , vol.9 , pp. 1683-1694
    • Mazur, I.1
  • 19
    • 33846061693 scopus 로고    scopus 로고
    • Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus
    • Mibayashi M, et al. 2007. Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J. Virol. 81:514-524.
    • (2007) J. Virol. , vol.81 , pp. 514-524
    • Mibayashi, M.1
  • 20
    • 0347927258 scopus 로고    scopus 로고
    • Lymphotoxin and lipopolysaccharide induce NF-κB-p52 generation by a co-translational mechanism
    • Mordmüller B, Krappmann D, Esen M, Wegener E, Scheidereit C. 2003. Lymphotoxin and lipopolysaccharide induce NF-κB-p52 generation by a co-translational mechanism. EMBO Rep. 4:82-87.
    • (2003) EMBO Rep. , vol.4 , pp. 82-87
    • Mordmüller, B.1    Krappmann, D.2    Esen, M.3    Wegener, E.4    Scheidereit, C.5
  • 21
    • 79960889928 scopus 로고    scopus 로고
    • Non-structural protein 1 of avian influenza A viruses differentially inhibit NF-κB promoter activation
    • M, Zohari S, Berg M. 2011. Non-structural protein 1 of avian influenza A viruses differentially inhibit NF-κB promoter activation. Virol. J. 8:383.
    • (2011) Virol. J. , vol.8 , pp. 383
    • Zohari, M.S.1    Berg, M.2
  • 22
    • 4043118343 scopus 로고    scopus 로고
    • Active NF-kappaB signalling is a prerequisite for influenza virus infection
    • Nimmerjahn F, et al. 2004. Active NF-kappaB signalling is a prerequisite for influenza virus infection. J. Gen. Virol. 85:2347-2356.
    • (2004) J. Gen. Virol. , vol.85 , pp. 2347-2356
    • Nimmerjahn, F.1
  • 23
    • 33947171000 scopus 로고    scopus 로고
    • IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein
    • Opitz B, et al. 2007. IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein. Cell. Microbiol. 9:930-938.
    • (2007) Cell. Microbiol. , vol.9 , pp. 930-938
    • Opitz, B.1
  • 24
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl HL. 1999. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18:6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 25
    • 57149092384 scopus 로고    scopus 로고
    • Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression
    • doi:10.1371/journal.ppat.1000196
    • Pauli E-K, et al. 2008. Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression. PLoS Pathog. 4:e1000196. doi:10.1371/journal.ppat.1000196.
    • (2008) PLoS Pathog. , vol.4
    • Pauli, E.-K.1
  • 26
    • 33845930736 scopus 로고    scopus 로고
    • Multiple NF-κB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells
    • Pietilä TE, et al. 2007. Multiple NF-κB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells. J. Immunol. 178:253-261.
    • (2007) J. Immunol. , vol.178 , pp. 253-261
    • Pietilä, T.E.1
  • 27
    • 34347376776 scopus 로고    scopus 로고
    • Role of lymphotoxin and homeostatic chemokines in the development and function of local lymphoid tissues in the respiratory tract
    • Rangel-Moreno J, Carragher D, Randall TD. 2007. Role of lymphotoxin and homeostatic chemokines in the development and function of local lymphoid tissues in the respiratory tract. Inmunologia 26:13-28.
    • (2007) Inmunologia , vol.26 , pp. 13-28
    • Rangel-Moreno, J.1    Carragher, D.2    Randall, T.D.3
  • 28
    • 77954124395 scopus 로고    scopus 로고
    • Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome
    • Schmolke M, Viemann D, Roth J, Ludwig S. 2009. Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome. J. Immunol. 183:5180-5189.
    • (2009) J. Immunol. , vol.183 , pp. 5180-5189
    • Schmolke, M.1    Viemann, D.2    Roth, J.3    Ludwig, S.4
  • 29
    • 17944378526 scopus 로고    scopus 로고
    • Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway
    • Senftleben U, et al. 2001. Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway. Science 293:1495-1499.
    • (2001) Science , vol.293 , pp. 1495-1499
    • Senftleben, U.1
  • 31
    • 0034466776 scopus 로고    scopus 로고
    • Influenza A virus NS1 protein prevents activation of NF-κB and induction of alpha/beta interferon
    • Wang X, et al. 2000. Influenza A virus NS1 protein prevents activation of NF-κB and induction of alpha/beta interferon. J. Virol. 74:11566-11573.
    • (2000) J. Virol. , vol.74 , pp. 11566-11573
    • Wang, X.1
  • 32
    • 33744961633 scopus 로고    scopus 로고
    • NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity
    • Wei L, et al. 2006. NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity. J. Biol. Chem. 281:11678-11684.
    • (2006) J. Biol. Chem. , vol.281 , pp. 11678-11684
    • Wei, L.1
  • 33
    • 3843130838 scopus 로고    scopus 로고
    • NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation
    • Wurzer WJ, et al. 2004. NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation. J. Biol. Chem. 279:30931-30937.
    • (2004) J. Biol. Chem. , vol.279 , pp. 30931-30937
    • Wurzer, W.J.1
  • 34
    • 0038521274 scopus 로고    scopus 로고
    • Caspase 3 activation is essential for efficient influenza virus propagation
    • Wurzer WJ, et al. 2003. Caspase 3 activation is essential for efficient influenza virus propagation. EMBO J. 22:2717-2728.
    • (2003) EMBO J. , vol.22 , pp. 2717-2728
    • Wurzer, W.J.1
  • 35
    • 3142663912 scopus 로고    scopus 로고
    • Induction of p100 processing by NF-κBinducing kinase involves docking IκB kinase α (IKKα) to p100 and IKKα-mediated phosphorylation
    • Xiao G, Fong A, Sun S-C. 2004. Induction of p100 processing by NF-κBinducing kinase involves docking IκB kinase α (IKKα) to p100 and IKKα-mediated phosphorylation. J. Biol. Chem. 279:30099-30105.
    • (2004) J. Biol. Chem. , vol.279 , pp. 30099-30105
    • Xiao, G.1    Fong, A.2    Sun, S.-C.3
  • 36
    • 0034745420 scopus 로고    scopus 로고
    • NF-κB-inducing kinase regulates the processing of NF-κB2 p100
    • Xiao G, Harhaj EW, Sun S-C. 2001. NF-κB-inducing kinase regulates the processing of NF-κB2 p100. Mol. Cell 7:401-409.
    • (2001) Mol. Cell. , vol.7 , pp. 401-409
    • Xiao, G.1    Harhaj, E.W.2    Sun, S.-C.3
  • 37
    • 0032487857 scopus 로고    scopus 로고
    • The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
    • Yin M-J, Yamamoto Y, Gaynor RB. 1998. The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β. Nature 396:77-80.
    • (1998) Nature , vol.396 , pp. 77-80
    • Yin, M-J.1    Yamamoto, Y.2    Gaynor, R.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.