메뉴 건너뛰기




Volumn 62, Issue 2, 2014, Pages 131-144

The role of glycogen synthase kinase 3-β in immunity and cell cycle: Implications in esophageal cancer

Author keywords

Esophageal cancer; GSK3; Inflammation; Inflammatory cytokines; PI3K

Indexed keywords

BETA CATENIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN C JUN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

EID: 84896546981     PISSN: 0004069X     EISSN: 16614917     Source Type: Journal    
DOI: 10.1007/s00005-013-0263-9     Document Type: Review
Times cited : (15)

References (176)
  • 1
    • 1642334954 scopus 로고    scopus 로고
    • NF-kappaB activation in esophageal adenocarcinoma: Relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy
    • Abdel-Latif MM, O'Riordan J, Windle HJ et al (2004) NF-kappaB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy. Ann Surg 239:491-500
    • (2004) Ann Surg , vol.239 , pp. 491-500
    • Abdel-Latif, M.M.1    O'Riordan, J.2    Windle, H.J.3
  • 2
    • 63649137892 scopus 로고    scopus 로고
    • Potential role of NF-kappaB in esophageal adenocarcinoma: As an emerging molecular target
    • Abdel-Latif MM, Kelleher D, Reynolds JV (2009) Potential role of NF-kappaB in esophageal adenocarcinoma: as an emerging molecular target. J Surg Res 153:172-180
    • (2009) J Surg Res , vol.153 , pp. 172-180
    • Abdel-Latif, M.M.1    Kelleher, D.2    Reynolds, J.V.3
  • 3
    • 84878280158 scopus 로고    scopus 로고
    • Angiotensin II causes imbalance between pro- and anti-inflammatory cytokines by modulating GSK-3beta in neuronal culture
    • Agarwal D, Dange RB, Raizada MK et al (2013) Angiotensin II causes imbalance between pro- and anti-inflammatory cytokines by modulating GSK-3beta in neuronal culture. Br J Pharmacol 169:860-874
    • (2013) Br J Pharmacol , vol.169 , pp. 860-874
    • Agarwal, D.1    Dange, R.B.2    Raizada, M.K.3
  • 4
    • 0035413614 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3: Properties, functions, and regulation
    • Ali A, Hoeflich KP, Woodgett JR (2001) Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev 101:2527-2540
    • (2001) Chem Rev , vol.101 , pp. 2527-2540
    • Ali, A.1    Hoeflich, K.P.2    Woodgett, J.R.3
  • 5
    • 13044312087 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 occurs in both squamous carcinomas and adenocarcinomas of the esophagus and in adenocarcinomas of the stomach
    • Arber N, Gammon MD, Hibshoosh H et al (1999) Overexpression of cyclin D1 occurs in both squamous carcinomas and adenocarcinomas of the esophagus and in adenocarcinomas of the stomach. Hum Pathol 30:1087-1092
    • (1999) Hum Pathol , vol.30 , pp. 1087-1092
    • Arber, N.1    Gammon, M.D.2    Hibshoosh, H.3
  • 6
    • 0036468297 scopus 로고    scopus 로고
    • Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines
    • Arlt A, Vorndamm J, Muerkoster S et al (2002) Autocrine production of interleukin 1beta confers constitutive nuclear factor kappaB activity and chemoresistance in pancreatic carcinoma cell lines. Cancer Res 62:910-916
    • (2002) Cancer Res , vol.62 , pp. 910-916
    • Arlt, A.1    Vorndamm, J.2    Muerkoster, S.3
  • 7
    • 0037130471 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1- dependent pathway
    • Arnott CH, Scott KA, Moore RJ et al (2002) Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1- dependent pathway. Oncogene 21:4728-4738
    • (2002) Oncogene , vol.21 , pp. 4728-4738
    • Arnott, C.H.1    Scott, K.A.2    Moore, R.J.3
  • 8
    • 0034688230 scopus 로고    scopus 로고
    • Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: Association with human esophageal cancer
    • Bahl R, Arora S, Nath N et al (2000) Novel polymorphism in p21(waf1/cip1) cyclin dependent kinase inhibitor gene: association with human esophageal cancer. Oncogene 19:323-328
    • (2000) Oncogene , vol.19 , pp. 323-328
    • Bahl, R.1    Arora, S.2    Nath, N.3
  • 9
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F, Mantovani A (2001) Inflammation and cancer: back to Virchow? Lancet 357:539-545
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 10
    • 77956172120 scopus 로고    scopus 로고
    • Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone
    • Ban JO, Kwak DH, Oh JH et al (2010) Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone. Chem Biol Interact 188:75-85
    • (2010) Chem Biol Interact , vol.188 , pp. 75-85
    • Ban, J.O.1    Kwak, D.H.2    Oh, J.H.3
  • 11
    • 58149202128 scopus 로고    scopus 로고
    • Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
    • Baud V, Karin M (2009) Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. Nat Rev Drug Discov 8:33-40
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 33-40
    • Baud, V.1    Karin, M.2
  • 12
    • 39049122786 scopus 로고    scopus 로고
    • t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism
    • Belkhiri A, Dar AA, Zaika A et al (2008) t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism. Cancer Res 68:395-403
    • (2008) Cancer Res , vol.68 , pp. 395-403
    • Belkhiri, A.1    Dar, A.A.2    Zaika, A.3
  • 13
    • 0037085768 scopus 로고    scopus 로고
    • Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism
    • Benchetrit F, Ciree A, Vives V et al (2002) Interleukin-17 inhibits tumor cell growth by means of a T-cell-dependent mechanism. Blood 99:2114-2121
    • (2002) Blood , vol.99 , pp. 2114-2121
    • Benchetrit, F.1    Ciree, A.2    Vives, V.3
  • 14
    • 52049094596 scopus 로고    scopus 로고
    • Differential regulation of STAT family members by glycogen synthase kinase-3
    • Beurel E, Jope RS (2008) Differential regulation of STAT family members by glycogen synthase kinase-3. J Biol Chem 283:21934-21944
    • (2008) J Biol Chem , vol.283 , pp. 21934-21944
    • Beurel, E.1    Jope, R.S.2
  • 15
    • 79251584980 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells
    • Beurel E, Yeh WI, Michalek SM et al (2010) Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells. J Immunol 186:1391-1398
    • (2010) J Immunol , vol.186 , pp. 1391-1398
    • Beurel, E.1    Yeh, W.I.2    Michalek, S.M.3
  • 16
    • 0026028040 scopus 로고
    • Rising incidence of adenocarcinoma of the esophagus and gastric cardia
    • Blot WJ, Devesa SS, Kneller RW et al (1991) Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 265:1287-1289
    • (1991) JAMA , vol.265 , pp. 1287-1289
    • Blot, W.J.1    Devesa, S.S.2    Kneller, R.W.3
  • 17
    • 78149360152 scopus 로고    scopus 로고
    • H. pylori infection is a key risk factor for proximal gastric cancer
    • Bornschein J, Selgrad M, Warnecke M et al (2010) H. pylori infection is a key risk factor for proximal gastric cancer. Dig Dis Sci 55:3124-3131
    • (2010) Dig Dis Sci , vol.55 , pp. 3124-3131
    • Bornschein, J.1    Selgrad, M.2    Warnecke, M.3
  • 18
    • 0032486258 scopus 로고    scopus 로고
    • The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells
    • Brady MJ, Bourbonais FJ, Saltiel AR (1998) The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells. J Biol Chem 273:14063-14066
    • (1998) J Biol Chem , vol.273 , pp. 14063-14066
    • Brady, M.J.1    Bourbonais, F.J.2    Saltiel, A.R.3
  • 19
    • 30444458235 scopus 로고    scopus 로고
    • Stats: Multifaceted regulators of transcription
    • Brierley MM, Fish EN (2005) Stats: multifaceted regulators of transcription. J Interferon Cytokine Res 25:733-744
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 733-744
    • Brierley, M.M.1    Fish, E.N.2
  • 20
    • 9644262497 scopus 로고    scopus 로고
    • Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity
    • Buss H, Dorrie A, Schmitz ML et al (2004) Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity. J Biol Chem 279:49571-49574
    • (2004) J Biol Chem , vol.279 , pp. 49571-49574
    • Buss, H.1    Dorrie, A.2    Schmitz, M.L.3
  • 21
    • 33644967242 scopus 로고    scopus 로고
    • Wnt signaling: Complexity at the surface
    • Cadigan KM, Liu YI (2006) Wnt signaling: complexity at the surface. J Cell Sci 119:395-402
    • (2006) J Cell Sci , vol.119 , pp. 395-402
    • Cadigan, K.M.1    Liu, Y.I.2
  • 22
    • 33746239119 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells
    • Cao Q, Lu X, Feng YJ (2006) Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells. Cell Res 16:671-677
    • (2006) Cell Res , vol.16 , pp. 671-677
    • Cao, Q.1    Lu, X.2    Feng, Y.J.3
  • 23
    • 77956130043 scopus 로고    scopus 로고
    • Oesophageal squamous cell carcinoma in a young adult with IL-12R beta 1 deficiency
    • Cardenes M, Angel-Moreno A, Fieschi C et al (2010) Oesophageal squamous cell carcinoma in a young adult with IL-12R beta 1 deficiency. J Med Genet 47:635-637
    • (2010) J Med Genet , vol.47 , pp. 635-637
    • Cardenes, M.1    Angel-Moreno, A.2    Fieschi, C.3
  • 24
    • 34250161576 scopus 로고    scopus 로고
    • Bax upregulation may provide a rationale for the low incidence of esophageal adenocarcinoma in a Greek cohort of patients with Barrett's esophagus
    • Chatzopoulos D, Kyrgidis A, Kountouras J et al (2007) Bax upregulation may provide a rationale for the low incidence of esophageal adenocarcinoma in a Greek cohort of patients with Barrett's esophagus. Hepatogastroenterology 54:705-709
    • (2007) Hepatogastroenterology , vol.54 , pp. 705-709
    • Chatzopoulos, D.1    Kyrgidis, A.2    Kountouras, J.3
  • 25
    • 83955162317 scopus 로고    scopus 로고
    • Increased IL-17-producing CD4(+) T cells in patients with esophageal cancer
    • Chen D, Hu Q, Mao C et al (2012a) Increased IL-17-producing CD4(+) T cells in patients with esophageal cancer. Cell Immunol 272:166-174
    • (2012) Cell Immunol , vol.272 , pp. 166-174
    • Chen, D.1    Hu, Q.2    Mao, C.3
  • 26
    • 84857364184 scopus 로고    scopus 로고
    • Role of interleukin 1 beta in esophageal squamous cell carcinoma
    • Chen MF, Lu MS, Chen PT et al (2012b) Role of interleukin 1 beta in esophageal squamous cell carcinoma. J Mol Med 90:89-100
    • (2012) J Mol Med , vol.90 , pp. 89-100
    • Chen, M.F.1    Lu, M.S.2    Chen, P.T.3
  • 27
    • 0035957937 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK-and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism
    • Cheng N, Chen J (2001) Tumor necrosis factor-alpha induction of endothelial ephrin A1 expression is mediated by a p38 MAPK-and SAPK/JNK-dependent but nuclear factor-kappa B-independent mechanism. J Biol Chem 276:13771-13777
    • (2001) J Biol Chem , vol.276 , pp. 13771-13777
    • Cheng, N.1    Chen, J.2
  • 28
    • 2342530749 scopus 로고    scopus 로고
    • EUROCARE-3 summary: Cancer survival in Europe at the end of the 20th century
    • Coleman MP, Gatta G, Verdecchia A et al (2003) EUROCARE-3 summary: cancer survival in Europe at the end of the 20th century. Ann Oncol 14(Suppl 5):v128-v149
    • (2003) Ann Oncol , vol.14 , Issue.SUPPL. 5
    • Coleman, M.P.1    Gatta, G.2    Verdecchia, A.3
  • 29
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • Colotta F, Allavena P, Sica A et al (2009) Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30:1073-1081
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3
  • 30
    • 4043144935 scopus 로고    scopus 로고
    • Epidemiology of upper gastrointestinal malignancies
    • Crew KD, Neugut AI (2004) Epidemiology of upper gastrointestinal malignancies. Semin Oncol 31:450-464
    • (2004) Semin Oncol , vol.31 , pp. 450-464
    • Crew, K.D.1    Neugut, A.I.2
  • 31
    • 0027978816 scopus 로고
    • The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: Evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf
    • Cross DA, Alessi DR, Vandenheede JR et al (1994) The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf. Biochem J 303(Pt 1):21-26
    • (1994) Biochem J , vol.303 , Issue.PART 1 , pp. 21-26
    • Cross, D.A.1    Alessi, D.R.2    Vandenheede, J.R.3
  • 32
    • 0032832808 scopus 로고    scopus 로고
    • Activation of Jun N-terminal kinase/stress-activated protein kinase pathway by tumor necrosis factor alpha leads to intercellular adhesion molecule-1 expression
    • De Cesaris P, Starace D, Starace G et al (1999) Activation of Jun N-terminal kinase/stress-activated protein kinase pathway by tumor necrosis factor alpha leads to intercellular adhesion molecule-1 expression. J Biol Chem 274:28978-28982
    • (1999) J Biol Chem , vol.274 , pp. 28978-28982
    • De Cesaris, P.1    Starace, D.2    Starace, G.3
  • 33
    • 33845265094 scopus 로고    scopus 로고
    • Elevated tumour interleukin-1beta is associated with systemic inflammation: A marker of reduced survival in gastro-oesophageal cancer
    • Deans DA, Wigmore SJ, Gilmour H et al (2006) Elevated tumour interleukin-1beta is associated with systemic inflammation: a marker of reduced survival in gastro-oesophageal cancer. Br J Cancer 95:1568-1575
    • (2006) Br J Cancer , vol.95 , pp. 1568-1575
    • Deans, D.A.1    Wigmore, S.J.2    Gilmour, H.3
  • 34
    • 0036781671 scopus 로고    scopus 로고
    • beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer
    • Deng J, Miller SA, Wang HY et al (2002) beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer. Cancer Cell 2:323-334
    • (2002) Cancer Cell , vol.2 , pp. 323-334
    • Deng, J.1    Miller, S.A.2    Wang, H.Y.3
  • 35
    • 4243687105 scopus 로고    scopus 로고
    • The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: The JB6 model is predictive
    • Dhar A, Young MR, Colburn NH (2002) The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive. Mol Cell Biochem 234-235:185-193
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 185-193
    • Dhar, A.1    Young, M.R.2    Colburn, N.H.3
  • 36
    • 33846873065 scopus 로고    scopus 로고
    • Serum interleukin-12 and interleukin-18 levels in patients with oesophageal squamous cell carcinoma
    • Diakowska D, Markocka-Maczka K, Grabowski K et al (2006) Serum interleukin-12 and interleukin-18 levels in patients with oesophageal squamous cell carcinoma. Exp Oncol 28:319-322
    • (2006) Exp Oncol , vol.28 , pp. 319-322
    • Diakowska, D.1    Markocka-Maczka, K.2    Grabowski, K.3
  • 37
    • 79955148909 scopus 로고    scopus 로고
    • A clinical perspective of IL-1beta as the gatekeeper of inflammation
    • Dinarello CA (2011) A clinical perspective of IL-1beta as the gatekeeper of inflammation. Eur J Immunol 41:1203-1217
    • (2011) Eur J Immunol , vol.41 , pp. 1203-1217
    • Dinarello, C.A.1
  • 38
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-tasking kinase
    • Doble BW, Woodgett JR (2003) GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 116:1175-1186
    • (2003) J Cell Sci , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 39
    • 0037627840 scopus 로고    scopus 로고
    • Current uses of isolated limb perfusion in the clinic and a model system for new strategies
    • Eggermont AM, de Wilt JH, ten Hagen TL (2003) Current uses of isolated limb perfusion in the clinic and a model system for new strategies. Lancet Oncol 4:429-437
    • (2003) Lancet Oncol , vol.4 , pp. 429-437
    • Eggermont, A.M.1    De Wilt, J.H.2    Ten Hagen, T.L.3
  • 40
    • 0035497352 scopus 로고    scopus 로고
    • Malignant transformation of the esophageal mucosa is enhanced in p27 knockout mice
    • Ellis FH Jr, Xu X, Kulke MH et al (2001) Malignant transformation of the esophageal mucosa is enhanced in p27 knockout mice. J Thorac Cardiovasc Surg 122:809-814
    • (2001) J Thorac Cardiovasc Surg , vol.122 , pp. 809-814
    • Ellis Jr., F.H.1    Xu, X.2    Kulke, M.H.3
  • 41
    • 0019026208 scopus 로고
    • Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
    • Embi N, Rylatt DB, Cohen P (1980) Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 107:519-527
    • (1980) Eur J Biochem , vol.107 , pp. 519-527
    • Embi, N.1    Rylatt, D.B.2    Cohen, P.3
  • 42
    • 63549084922 scopus 로고    scopus 로고
    • GSK3 beta N-terminus binding to p53 promotes its acetylation
    • Eom TY, Jope RS (2009) GSK3 beta N-terminus binding to p53 promotes its acetylation. Mol Cancer 8:14
    • (2009) Mol Cancer , vol.8 , pp. 14
    • Eom, T.Y.1    Jope, R.S.2
  • 43
    • 0033768682 scopus 로고    scopus 로고
    • The disease spectrum of Helicobacter pylori: The immunopathogenesis of gastroduodenal ulcer and gastric cancer
    • Ernst PB, Gold BD (2000) The disease spectrum of Helicobacter pylori: the immunopathogenesis of gastroduodenal ulcer and gastric cancer. Annu Rev Microbiol 54:615-640
    • (2000) Annu Rev Microbiol , vol.54 , pp. 615-640
    • Ernst, P.B.1    Gold, B.D.2
  • 44
    • 77957748309 scopus 로고    scopus 로고
    • Infectious causes of esophageal cancer
    • Eslick GD (2010) Infectious causes of esophageal cancer. Infect Dis Clin North Am 24:845-852, vii
    • (2010) Infect Dis Clin North Am , vol.24
    • Eslick, G.D.1
  • 45
    • 0036120653 scopus 로고    scopus 로고
    • Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway
    • Fang X, Yu S, Tanyi JL et al (2002) Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway. Mol Cell Biol 22:2099-2110
    • (2002) Mol Cell Biol , vol.22 , pp. 2099-2110
    • Fang, X.1    Yu, S.2    Tanyi, J.L.3
  • 46
    • 0037103258 scopus 로고    scopus 로고
    • The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia
    • Ferrajoli A, Keating MJ, Manshouri T et al (2002) The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia. Blood 100:1215-1219
    • (2002) Blood , vol.100 , pp. 1215-1219
    • Ferrajoli, A.1    Keating, M.J.2    Manshouri, T.3
  • 47
    • 0023656594 scopus 로고
    • Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3
    • Fiol CJ, Mahrenholz AM, Wang Y et al (1987) Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3. J Biol Chem 262:14042-14048
    • (1987) J Biol Chem , vol.262 , pp. 14042-14048
    • Fiol, C.J.1    Mahrenholz, A.M.2    Wang, Y.3
  • 48
    • 0036716699 scopus 로고    scopus 로고
    • Inflammatory gradient in Barrett's oesophagus: Implications for disease complications
    • Fitzgerald RC, Abdalla S, Onwuegbusi BA et al (2002a) Inflammatory gradient in Barrett's oesophagus: implications for disease complications. Gut 51:316-322
    • (2002) Gut , vol.51 , pp. 316-322
    • Fitzgerald, R.C.1    Abdalla, S.2    Onwuegbusi, B.A.3
  • 49
    • 0036278756 scopus 로고    scopus 로고
    • Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: Immunological determinants
    • Fitzgerald RC, Onwuegbusi BA, Bajaj-Elliott M et al (2002b) Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants. Gut 50:451-459
    • (2002) Gut , vol.50 , pp. 451-459
    • Fitzgerald, R.C.1    Onwuegbusi, B.A.2    Bajaj-Elliott, M.3
  • 50
    • 0034969088 scopus 로고    scopus 로고
    • A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation
    • Frame S, Cohen P, Biondi RM (2001) A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation. Mol Cell 7:1321-1327
    • (2001) Mol Cell , vol.7 , pp. 1321-1327
    • Frame, S.1    Cohen, P.2    Biondi, R.M.3
  • 51
    • 0029956823 scopus 로고    scopus 로고
    • Determination of the prognostic significance of unscheduled cyclin A overexpression in patients with esophageal squamous cell carcinoma
    • Furihata M, Ishikawa T, Inoue A et al (1996) Determination of the prognostic significance of unscheduled cyclin A overexpression in patients with esophageal squamous cell carcinoma. Clin Cancer Res 2:1781-1785
    • (1996) Clin Cancer Res , vol.2 , pp. 1781-1785
    • Furihata, M.1    Ishikawa, T.2    Inoue, A.3
  • 52
    • 34247868174 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 beta; a new target in pancreatic cancer?
    • Garcea G, Manson MM, Neal CP et al (2007) Glycogen synthase kinase-3 beta; a new target in pancreatic cancer? Curr Cancer Drug Targets 7:209-215
    • (2007) Curr Cancer Drug Targets , vol.7 , pp. 209-215
    • Garcea, G.1    Manson, M.M.2    Neal, C.P.3
  • 53
    • 58849102628 scopus 로고    scopus 로고
    • Antigenic experience dictates functional role of glycogen synthase kinase-3 in human CD4? T cell responses
    • Garcia CA, Benakanakere MR, Alard P et al (2008) Antigenic experience dictates functional role of glycogen synthase kinase-3 in human CD4? T cell responses. J Immunol 181:8363-8371
    • (2008) J Immunol , vol.181 , pp. 8363-8371
    • Garcia, C.A.1    Benakanakere, M.R.2    Alard, P.3
  • 54
    • 70449698534 scopus 로고    scopus 로고
    • c-jun controls the ability of IL-12 to induce IL-10 production from human memory CD4? T cells
    • Garcia CA, Wang H, Benakanakere MR et al (2009) c-jun controls the ability of IL-12 to induce IL-10 production from human memory CD4? T cells. J Immunol 183:4475-4482
    • (2009) J Immunol , vol.183 , pp. 4475-4482
    • Garcia, C.A.1    Wang, H.2    Benakanakere, M.R.3
  • 55
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli F, Apetoh L, Tesniere A et al (2009) Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 15:1170-1178
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1    Apetoh, L.2    Tesniere, A.3
  • 56
    • 20444475324 scopus 로고    scopus 로고
    • Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells
    • Ghosh JC, Altieri DC (2005) Activation of p53-dependent apoptosis by acute ablation of glycogen synthase kinase-3beta in colorectal cancer cells. Clin Cancer Res 11:4580-4588
    • (2005) Clin Cancer Res , vol.11 , pp. 4580-4588
    • Ghosh, J.C.1    Altieri, D.C.2
  • 57
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140:883-899
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 58
    • 33745683734 scopus 로고    scopus 로고
    • Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells
    • Grzesiak JJ, Smith KC, Chalberg C et al (2005) Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells. Int J Gastrointest Cancer 36:131-146
    • (2005) Int J Gastrointest Cancer , vol.36 , pp. 131-146
    • Grzesiak, J.J.1    Smith, K.C.2    Chalberg, C.3
  • 59
    • 0037319102 scopus 로고    scopus 로고
    • Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model
    • Gupta VK, Park JO, Kurihara T et al (2003) Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model. Gene Ther 10:206-212
    • (2003) Gene Ther , vol.10 , pp. 206-212
    • Gupta, V.K.1    Park, J.O.2    Kurihara, T.3
  • 60
    • 0033807824 scopus 로고    scopus 로고
    • Apoptosis and cell proliferation in the metaplasia-dysplasia-carcinoma- sequence of Barrett's esophagus
    • Halm U, Tannapfel A, Breitung B et al (2000) Apoptosis and cell proliferation in the metaplasia-dysplasia-carcinoma-sequence of Barrett's esophagus. Hepatogastroenterology 47:962-966
    • (2000) Hepatogastroenterology , vol.47 , pp. 962-966
    • Halm, U.1    Tannapfel, A.2    Breitung, B.3
  • 61
    • 0027770021 scopus 로고
    • Regulation of matrix metalloproteinase expression in human vein and micro-vascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester
    • Hanemaaijer R, Koolwijk P, le Clercq L et al (1993) Regulation of matrix metalloproteinase expression in human vein and micro-vascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester. Biochem J 296 (Pt 3):803-809
    • (1993) Biochem J , vol.296 , Issue.PART 3 , pp. 803-809
    • Hanemaaijer, R.1    Koolwijk, P.2    Le Clercq, L.3
  • 62
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR et al (2005) Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6:1123-1132
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 63
    • 0031429943 scopus 로고    scopus 로고
    • Signaling mechanisms through gp130: A model of the cytokine system
    • Hirano T, Nakajima K, Hibi M (1997) Signaling mechanisms through gp130: a model of the cytokine system. Cytokine Growth Factor Rev 8:241-252
    • (1997) Cytokine Growth Factor Rev , vol.8 , pp. 241-252
    • Hirano, T.1    Nakajima, K.2    Hibi, M.3
  • 64
    • 84860849870 scopus 로고    scopus 로고
    • Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma
    • Ho WC, Pikor L, Gao Y et al (2012) Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma. J Biol Chem 287:15458-15465
    • (2012) J Biol Chem , vol.287 , pp. 15458-15465
    • Ho, W.C.1    Pikor, L.2    Gao, Y.3
  • 65
    • 27544476971 scopus 로고    scopus 로고
    • The role of IL-6 and STAT3 in inflammation and cancer
    • Hodge DR, Hurt EM, Farrar WL (2005) The role of IL-6 and STAT3 in inflammation and cancer. Eur J Cancer 41:2502-2512
    • (2005) Eur J Cancer , vol.41 , pp. 2502-2512
    • Hodge, D.R.1    Hurt, E.M.2    Farrar, W.L.3
  • 66
    • 33646495723 scopus 로고    scopus 로고
    • Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts
    • Honorati MC, Neri S, Cattini L et al (2006) Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts. Osteoarthritis Cartilage 14:345-352
    • (2006) Osteoarthritis Cartilage , vol.14 , pp. 345-352
    • Honorati, M.C.1    Neri, S.2    Cattini, L.3
  • 67
    • 0036912873 scopus 로고    scopus 로고
    • Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma
    • Huang SP, Wu MS, Wang HP et al (2002) Correlation between serum levels of interleukin-6 and vascular endothelial growth factor in gastric carcinoma. J Gastroenterol Hepatol 17:1165-1169
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 1165-1169
    • Huang, S.P.1    Wu, M.S.2    Wang, H.P.3
  • 68
    • 35648983903 scopus 로고    scopus 로고
    • Inflammation and cancer: An ancient link with novel potentials
    • Hussain SP, Harris CC (2007) Inflammation and cancer: an ancient link with novel potentials. Int J Cancer 121:2373-2380
    • (2007) Int J Cancer , vol.121 , pp. 2373-2380
    • Hussain, S.P.1    Harris, C.C.2
  • 69
    • 70449413106 scopus 로고    scopus 로고
    • Transcription factor AP-1 in esophageal squamous cell carcinoma: Alterations in activity and expression during human Papillomavirus infection
    • Hussain S, Bharti AC, Salam I et al (2009) Transcription factor AP-1 in esophageal squamous cell carcinoma: alterations in activity and expression during human Papillomavirus infection. BMC Cancer 9:329
    • (2009) BMC Cancer , vol.9 , pp. 329
    • Hussain, S.1    Bharti, A.C.2    Salam, I.3
  • 70
    • 3042599473 scopus 로고    scopus 로고
    • Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: The role of inflammation
    • Itzkowitz SH, Yio X (2004) Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol 287:G7-G17
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • Itzkowitz, S.H.1    Yio, X.2
  • 71
    • 0026720446 scopus 로고
    • Amplification and expression of the human cyclin D gene in esophageal cancer
    • Jiang W, Kahn SM, Tomita N et al (1992) Amplification and expression of the human cyclin D gene in esophageal cancer. Cancer Res 52:2980-2983
    • (1992) Cancer Res , vol.52 , pp. 2980-2983
    • Jiang, W.1    Kahn, S.M.2    Tomita, N.3
  • 72
    • 33644514613 scopus 로고    scopus 로고
    • C-fos assessment as a marker of anti-epidermal growth factor receptor effect
    • Jimeno A, Kulesza P, Kincaid E et al (2006) C-fos assessment as a marker of anti-epidermal growth factor receptor effect. Cancer Res 66:2385-2390
    • (2006) Cancer Res , vol.66 , pp. 2385-2390
    • Jimeno, A.1    Kulesza, P.2    Kincaid, E.3
  • 73
    • 0442276554 scopus 로고    scopus 로고
    • The glamour and gloom of glycogen synthase kinase-3
    • Jope RS, Johnson GV (2004) The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 29:95-102
    • (2004) Trends Biochem Sci , vol.29 , pp. 95-102
    • Jope, R.S.1    Johnson, G.V.2
  • 74
    • 33947597084 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
    • Jope RS, Yuskaitis CJ, Beurel E (2007) Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 32:577-595
    • (2007) Neurochem Res , vol.32 , pp. 577-595
    • Jope, R.S.1    Yuskaitis, C.J.2    Beurel, E.3
  • 75
    • 34547136180 scopus 로고    scopus 로고
    • Low expression of Bax predicts poor prognosis in patients with locally advanced esophageal cancer treated with definitive chemoradiotherapy
    • Kang SY, Han JH, Lee KJ et al (2007) Low expression of Bax predicts poor prognosis in patients with locally advanced esophageal cancer treated with definitive chemoradiotherapy. Clin Cancer Res 13:4146-4153
    • (2007) Clin Cancer Res , vol.13 , pp. 4146-4153
    • Kang, S.Y.1    Han, J.H.2    Lee, K.J.3
  • 76
    • 37349094929 scopus 로고    scopus 로고
    • GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers
    • Kang T, Wei Y, Honaker Y et al (2008) GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. Cancer Cell 13:36-47
    • (2008) Cancer Cell , vol.13 , pp. 36-47
    • Kang, T.1    Wei, Y.2    Honaker, Y.3
  • 77
    • 0032744268 scopus 로고    scopus 로고
    • Interleukin-17 stimulates the expression of IkappaB alpha mRNA and the secretion of IL-6 and IL-8 in glioblastoma cell lines
    • Kehlen A, Thiele K, Riemann D et al (1999) Interleukin-17 stimulates the expression of IkappaB alpha mRNA and the secretion of IL-6 and IL-8 in glioblastoma cell lines. J Neuroimmunol 101:1-6
    • (1999) J Neuroimmunol , vol.101 , pp. 1-6
    • Kehlen, A.1    Thiele, K.2    Riemann, D.3
  • 78
    • 0037306435 scopus 로고    scopus 로고
    • Cytotoxicity in glioma cells due to interleukin-12 and interleukin-18-stimulated macrophages mediated by interferon-gamma-regulated nitric oxide
    • Kito T, Kuroda E, Yokota A et al (2003) Cytotoxicity in glioma cells due to interleukin-12 and interleukin-18-stimulated macrophages mediated by interferon-gamma-regulated nitric oxide. J Neurosurg 98:385-392
    • (2003) J Neurosurg , vol.98 , pp. 385-392
    • Kito, T.1    Kuroda, E.2    Yokota, A.3
  • 79
    • 33750867472 scopus 로고    scopus 로고
    • Glycogen synthase kinase- 3 - an overview of an over-achieving protein kinase
    • Kockeritz L, Doble B, Patel S et al (2006) Glycogen synthase kinase- 3 - an overview of an over-achieving protein kinase. Curr Drug Targets 7:1377-1388
    • (2006) Curr Drug Targets , vol.7 , pp. 1377-1388
    • Kockeritz, L.1    Doble, B.2    Patel, S.3
  • 80
    • 4444382263 scopus 로고    scopus 로고
    • Activation of NFkappaB represents the central event in the neoplastic progression associated with Barrett's esophagus: A possible link to the inflammation and overexpression of COX-2, PPARgamma and growth factors
    • Konturek PC, Nikiforuk A, Kania J et al (2004) Activation of NFkappaB represents the central event in the neoplastic progression associated with Barrett's esophagus: a possible link to the inflammation and overexpression of COX-2, PPARgamma and growth factors. Dig Dis Sci 49:1075-1083
    • (2004) Dig Dis Sci , vol.49 , pp. 1075-1083
    • Konturek, P.C.1    Nikiforuk, A.2    Kania, J.3
  • 81
    • 33847060965 scopus 로고    scopus 로고
    • Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors
    • Krelin Y, Voronov E, Dotan S et al (2007) Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res 67:1062-1071
    • (2007) Cancer Res , vol.67 , pp. 1062-1071
    • Krelin, Y.1    Voronov, E.2    Dotan, S.3
  • 82
    • 67651094058 scopus 로고    scopus 로고
    • Endogenous IL-17 contributes to reduced tumor growth and metastasis
    • Kryczek I, Wei S, Szeliga W et al (2009) Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 114:357-359
    • (2009) Blood , vol.114 , pp. 357-359
    • Kryczek, I.1    Wei, S.2    Szeliga, W.3
  • 83
    • 47849098044 scopus 로고    scopus 로고
    • Inflammation: Gearing the journey to cancer
    • Kundu JK, Surh YJ (2008) Inflammation: gearing the journey to cancer. Mutat Res 659:15-30
    • (2008) Mutat Res , vol.659 , pp. 15-30
    • Kundu, J.K.1    Surh, Y.J.2
  • 84
    • 0032770368 scopus 로고    scopus 로고
    • p53, p21(Waf1/Cip1) and cyclin D1 protein expression and prognosis in esophageal cancer
    • Kuwahara M, Hirai T, Yoshida K et al (1999) p53, p21(Waf1/Cip1) and cyclin D1 protein expression and prognosis in esophageal cancer. Dis Esophagus 12:116-119
    • (1999) Dis Esophagus , vol.12 , pp. 116-119
    • Kuwahara, M.1    Hirai, T.2    Yoshida, K.3
  • 85
    • 0344441877 scopus 로고    scopus 로고
    • Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways
    • Leu CM, Wong FH, Chang C et al (2003) Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogen-activated protein kinase pathways. Oncogene 22:7809-7818
    • (2003) Oncogene , vol.22 , pp. 7809-7818
    • Leu, C.M.1    Wong, F.H.2    Chang, C.3
  • 86
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I et al (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 87
    • 79953749145 scopus 로고    scopus 로고
    • The unholy trinity: Inflammation, cytokines, and STAT3 shape the cancer microenvironment
    • Li N, Grivennikov SI, Karin M (2011) The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment. Cancer Cell 19:429-431
    • (2011) Cancer Cell , vol.19 , pp. 429-431
    • Li, N.1    Grivennikov, S.I.2    Karin, M.3
  • 88
    • 79953667360 scopus 로고    scopus 로고
    • The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma
    • Lv L, Pan K, Li XD et al (2011) The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma. PLoS ONE 6:e18219
    • (2011) PLoS ONE , vol.6
    • Lv, L.1    Pan, K.2    Li, X.D.3
  • 89
    • 0030064148 scopus 로고    scopus 로고
    • The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells
    • Ma X, Chow JM, Gri G et al (1996) The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells. J Exp Med 183:147-157
    • (1996) J Exp Med , vol.183 , pp. 147-157
    • Ma, X.1    Chow, J.M.2    Gri, G.3
  • 90
    • 64549093266 scopus 로고    scopus 로고
    • Bleomycin-induced nuclear factor-kappaB activation in human bronchial epithelial cells involves the phosphorylation of glycogen synthase kinase 3beta
    • Ma Y, Wang M, Li N et al (2009) Bleomycin-induced nuclear factor-kappaB activation in human bronchial epithelial cells involves the phosphorylation of glycogen synthase kinase 3beta. Toxicol Lett 187:194-200
    • (2009) Toxicol Lett , vol.187 , pp. 194-200
    • Ma, Y.1    Wang, M.2    Li, N.3
  • 91
    • 79952716229 scopus 로고    scopus 로고
    • Contribution of IL-17- producing gamma delta T cells to the efficacy of anticancer chemotherapy
    • Ma Y, Aymeric L, Locher C et al (2011) Contribution of IL-17- producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med 208:491-503
    • (2011) J Exp Med , vol.208 , pp. 491-503
    • Ma, Y.1    Aymeric, L.2    Locher, C.3
  • 92
    • 72549086625 scopus 로고    scopus 로고
    • Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase
    • Mai W, Kawakami K, Shakoori A et al (2009) Deregulated GSK3{beta} sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase. Clin Cancer Res 15:6810-6819
    • (2009) Clin Cancer Res , vol.15 , pp. 6810-6819
    • Mai, W.1    Kawakami, K.2    Shakoori, A.3
  • 93
    • 0038393312 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer
    • Maihofner C, Charalambous MP, Bhambra U et al (2003) Expression of cyclooxygenase-2 parallels expression of interleukin-1beta, interleukin-6 and NF-kappaB in human colorectal cancer. Carcinogenesis 24:665-671
    • (2003) Carcinogenesis , vol.24 , pp. 665-671
    • Maihofner, C.1    Charalambous, M.P.2    Bhambra, U.3
  • 94
    • 79953839326 scopus 로고    scopus 로고
    • Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression
    • Maritz MF, van der Watt PJ, Holderness N et al (2011) Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression. Biol Chem 392:439-448
    • (2011) Biol Chem , vol.392 , pp. 439-448
    • Maritz, M.F.1    Van Der Watt, P.J.2    Holderness, N.3
  • 95
    • 23944486750 scopus 로고    scopus 로고
    • Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
    • Martin M, Rehani K, Jope RS et al (2005) Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat Immunol 6:777-784
    • (2005) Nat Immunol , vol.6 , pp. 777-784
    • Martin, M.1    Rehani, K.2    Jope, R.S.3
  • 97
    • 0032948578 scopus 로고    scopus 로고
    • Comparison of deregulated expression of cyclin D1 and cyclin E with that of cyclin-dependent kinase 4 (CDK4) and CDK2 in human oesophageal squamous cell carcinoma
    • Matsumoto M, Furihata M, Ishikawa T et al (1999) Comparison of deregulated expression of cyclin D1 and cyclin E with that of cyclin-dependent kinase 4 (CDK4) and CDK2 in human oesophageal squamous cell carcinoma. Br J Cancer 80:256-261
    • (1999) Br J Cancer , vol.80 , pp. 256-261
    • Matsumoto, M.1    Furihata, M.2    Ishikawa, T.3
  • 98
    • 79960426821 scopus 로고    scopus 로고
    • Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors
    • Mattarollo SR, Loi S, Duret H et al (2011) Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors. Cancer Res 71:4809-4820
    • (2011) Cancer Res , vol.71 , pp. 4809-4820
    • Mattarollo, S.R.1    Loi, S.2    Duret, H.3
  • 99
    • 79956298780 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells
    • Meares GP, Mines MA, Beurel E et al (2011) Glycogen synthase kinase-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells. Exp Cell Res 317:1621-1628
    • (2011) Exp Cell Res , vol.317 , pp. 1621-1628
    • Meares, G.P.1    Mines, M.A.2    Beurel, E.3
  • 100
    • 84858684216 scopus 로고    scopus 로고
    • NcoI TNF-beta gene polymorphism and TNF expression are associated with an increased risk of developing Barrett's esophagus and esophageal adenocarcinoma
    • Menke V, van Zoest KP, Moons LM et al (2012) NcoI TNF-beta gene polymorphism and TNF expression are associated with an increased risk of developing Barrett's esophagus and esophageal adenocarcinoma. Scand J Gastroenterol 47:378-386
    • (2012) Scand J Gastroenterol , vol.47 , pp. 378-386
    • Menke, V.1    Van Zoest, K.P.2    Moons, L.M.3
  • 101
    • 48449095742 scopus 로고    scopus 로고
    • STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 beta
    • Moh A, Zhang W, Yu S et al (2008) STAT3 sensitizes insulin signaling by negatively regulating glycogen synthase kinase-3 beta. Diabetes 57:1227-1235
    • (2008) Diabetes , vol.57 , pp. 1227-1235
    • Moh, A.1    Zhang, W.2    Yu, S.3
  • 102
    • 47249089615 scopus 로고    scopus 로고
    • A pro-inflammatory genotype predisposes to Barrett's esophagus
    • Moons LM, Kusters JG, van Delft JH et al (2008) A pro-inflammatory genotype predisposes to Barrett's esophagus. Carcinogenesis 29:926-931
    • (2008) Carcinogenesis , vol.29 , pp. 926-931
    • Moons, L.M.1    Kusters, J.G.2    Van Delft, J.H.3
  • 103
    • 0029090220 scopus 로고
    • Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes
    • Mu J, Zou JP, Yamamoto N et al (1995) Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes. Cancer Res 55:4404-4408
    • (1995) Cancer Res , vol.55 , pp. 4404-4408
    • Mu, J.1    Zou, J.P.2    Yamamoto, N.3
  • 104
    • 0035983533 scopus 로고    scopus 로고
    • Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3beta
    • Mukai F, Ishiguro K, Sano Y et al (2002) Alternative splicing isoform of tau protein kinase I/glycogen synthase kinase 3beta. J Neurochem 81:1073-1083
    • (2002) J Neurochem , vol.81 , pp. 1073-1083
    • Mukai, F.1    Ishiguro, K.2    Sano, Y.3
  • 105
    • 32944467415 scopus 로고    scopus 로고
    • The cyclin-dependent kinase 2 inhibitor down-regulates interleukin-1beta-mediated induction of cyclooxygenase-2 expression in human lung carcinoma cells
    • Mukhopadhyay P, Ali MA, Nandi A et al (2006) The cyclin-dependent kinase 2 inhibitor down-regulates interleukin-1beta-mediated induction of cyclooxygenase-2 expression in human lung carcinoma cells. Cancer Res 66:1758-1766
    • (2006) Cancer Res , vol.66 , pp. 1758-1766
    • Mukhopadhyay, P.1    Ali, M.A.2    Nandi, A.3
  • 106
    • 0027199126 scopus 로고
    • IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase
    • Murakami M, Hibi M, Nakagawa N et al (1993) IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. Science 260:1808-1810
    • (1993) Science , vol.260 , pp. 1808-1810
    • Murakami, M.1    Hibi, M.2    Nakagawa, N.3
  • 107
    • 0033044020 scopus 로고    scopus 로고
    • Determination of the prognostic significance of cyclin B1 overexpression in patients with esophageal squamous cell carcinoma
    • Murakami H, Furihata M, Ohtsuki Y et al (1999) Determination of the prognostic significance of cyclin B1 overexpression in patients with esophageal squamous cell carcinoma. Virchows Arch 434:153-158
    • (1999) Virchows Arch , vol.434 , pp. 153-158
    • Murakami, H.1    Furihata, M.2    Ohtsuki, Y.3
  • 108
    • 12344265532 scopus 로고    scopus 로고
    • Expression of p21(Waf1/ Cip1) predicts response and survival of esophageal cancer patients treated by chemoradiotherapy
    • Nakamura T, Hayashi K, Ota M et al (2004) Expression of p21(Waf1/ Cip1) predicts response and survival of esophageal cancer patients treated by chemoradiotherapy. Dis Esophagus 17:315-321
    • (2004) Dis Esophagus , vol.17 , pp. 315-321
    • Nakamura, T.1    Hayashi, K.2    Ota, M.3
  • 109
    • 40549087266 scopus 로고    scopus 로고
    • PI3 K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1)
    • Nakao T, Geddis AE, Fox NE et al (2008) PI3 K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1). Cell Cycle 7:257-266
    • (2008) Cell Cycle , vol.7 , pp. 257-266
    • Nakao, T.1    Geddis, A.E.2    Fox, N.E.3
  • 110
    • 39849088124 scopus 로고    scopus 로고
    • Molecular components of the adherens junction
    • Niessen CM, Gottardi CJ (2008) Molecular components of the adherens junction. Biochim Biophys Acta 1778:562-571
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 562-571
    • Niessen, C.M.1    Gottardi, C.J.2
  • 111
    • 50949130076 scopus 로고    scopus 로고
    • Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells
    • Ohtani M, Nagai S, Kondo S et al (2008) Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells. Blood 112:635-643
    • (2008) Blood , vol.112 , pp. 635-643
    • Ohtani, M.1    Nagai, S.2    Kondo, S.3
  • 112
    • 0034600901 scopus 로고    scopus 로고
    • Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3
    • Ohteki T, Parsons M, Zakarian A et al (2000) Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3. J Exp Med 192:99-104
    • (2000) J Exp Med , vol.192 , pp. 99-104
    • Ohteki, T.1    Parsons, M.2    Zakarian, A.3
  • 113
    • 0030478812 scopus 로고    scopus 로고
    • The influence of interleukin-6 on the growth of human esophageal cancer cell lines
    • Oka M, Iizuka N, Yamamoto K et al (1996a) The influence of interleukin-6 on the growth of human esophageal cancer cell lines. J Interferon Cytokine Res 16:1001-1006
    • (1996) J Interferon Cytokine Res , vol.16 , pp. 1001-1006
    • Oka, M.1    Iizuka, N.2    Yamamoto, K.3
  • 114
    • 9344266888 scopus 로고    scopus 로고
    • Relationship between serum levels of interleukin 6, various disease parameters and malnutrition in patients with esophageal squamous cell carcinoma
    • Oka M, Yamamoto K, Takahashi M et al (1996b) Relationship between serum levels of interleukin 6, various disease parameters and malnutrition in patients with esophageal squamous cell carcinoma. Cancer Res 56:2776-2780
    • (1996) Cancer Res , vol.56 , pp. 2776-2780
    • Oka, M.1    Yamamoto, K.2    Takahashi, M.3
  • 115
    • 79953719964 scopus 로고    scopus 로고
    • Role of Bcl-2 family proteins and caspases in the regulation of apoptosis
    • Ola MS, Nawaz M, Ahsan H (2011) Role of Bcl-2 family proteins and caspases in the regulation of apoptosis. Mol Cell Biochem 351:41-58
    • (2011) Mol Cell Biochem , vol.351 , pp. 41-58
    • Ola, M.S.1    Nawaz, M.2    Ahsan, H.3
  • 116
    • 21344432364 scopus 로고    scopus 로고
    • Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus
    • O'Riordan JM, Abdel-latif MM, Ravi N et al (2005) Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation- metaplasia-dysplasia-adenocarcinoma sequence in the esophagus. Am J Gastroenterol 100:1257-1264
    • (2005) Am J Gastroenterol , vol.100 , pp. 1257-1264
    • O'Riordan, J.M.1    Abdel-latif, M.M.2    Ravi, N.3
  • 117
    • 33749015218 scopus 로고    scopus 로고
    • Aberrant nuclear accumulation of glycogen synthase kinase- 3beta in human pancreatic cancer: Association with kinase activity and tumor dedifferentiation
    • Ougolkov AV, Fernandez-Zapico ME, Bilim VN et al (2006) Aberrant nuclear accumulation of glycogen synthase kinase- 3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiation. Clin Cancer Res 12:5074-5081
    • (2006) Clin Cancer Res , vol.12 , pp. 5074-5081
    • Ougolkov, A.V.1    Fernandez-Zapico, M.E.2    Bilim, V.N.3
  • 118
    • 34547114509 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells
    • Ougolkov AV, Bone ND, Fernandez-Zapico ME et al (2007) Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood 110:735-742
    • (2007) Blood , vol.110 , pp. 735-742
    • Ougolkov, A.V.1    Bone, N.D.2    Fernandez-Zapico, M.E.3
  • 119
    • 0028182749 scopus 로고
    • Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling
    • Pages F, Ragueneau M, Rottapel R et al (1994) Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature 369:327-329
    • (1994) Nature , vol.369 , pp. 327-329
    • Pages, F.1    Ragueneau, M.2    Rottapel, R.3
  • 120
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • Park H, Li Z, Yang XO et al (2005) A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6:1133-1141
    • (2005) Nat Immunol , vol.6 , pp. 1133-1141
    • Park, H.1    Li, Z.2    Yang, X.O.3
  • 121
    • 54549120290 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 and cancer: Good cop, bad cop?
    • Patel S, Woodgett J (2008) Glycogen synthase kinase-3 and cancer: good cop, bad cop? Cancer Cell 14:351-353
    • (2008) Cancer Cell , vol.14 , pp. 351-353
    • Patel, S.1    Woodgett, J.2
  • 122
    • 0035848705 scopus 로고    scopus 로고
    • Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front
    • Paweletz CP, Charboneau L, Bichsel VE et al (2001) Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene 20:1981-1989
    • (2001) Oncogene , vol.20 , pp. 1981-1989
    • Paweletz, C.P.1    Charboneau, L.2    Bichsel, V.E.3
  • 123
    • 0034283186 scopus 로고    scopus 로고
    • L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: Evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport
    • Peyrollier K, Hajduch E, Blair AS et al (2000) L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport. Biochem J 350(Pt 2):361-368
    • (2000) Biochem J , vol.350 , Issue.PART 2 , pp. 361-368
    • Peyrollier, K.1    Hajduch, E.2    Blair, A.S.3
  • 124
    • 0032962942 scopus 로고    scopus 로고
    • Role of NK and T cells in IL-12-induced anti-tumor response against hepatic colon carcinoma
    • Pham-Nguyen KB, Yang W, Saxena R et al (1999) Role of NK and T cells in IL-12-induced anti-tumor response against hepatic colon carcinoma. Int J Cancer 81:813-819
    • (1999) Int J Cancer , vol.81 , pp. 813-819
    • Pham-Nguyen, K.B.1    Yang, W.2    Saxena, R.3
  • 125
    • 59849109973 scopus 로고    scopus 로고
    • Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2
    • Rehani K, Wang H, Garcia CA et al (2009) Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2. J Immunol 182:547-553
    • (2009) J Immunol , vol.182 , pp. 547-553
    • Rehani, K.1    Wang, H.2    Garcia, C.A.3
  • 126
    • 0037155824 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation
    • Rossig L, Badorff C, Holzmann Y et al (2002) Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation. J Biol Chem 277:9684-9689
    • (2002) J Biol Chem , vol.277 , pp. 9684-9689
    • Rossig, L.1    Badorff, C.2    Holzmann, Y.3
  • 127
    • 0028393901 scopus 로고
    • TNF receptor number-dependent cytotoxicity to TNF-resistant human esophageal cancer cell lines by combination with recombinant human necrosis factor and hyperthermia
    • Saito T, Kato H, Saito M et al (1994a) TNF receptor number-dependent cytotoxicity to TNF-resistant human esophageal cancer cell lines by combination with recombinant human necrosis factor and hyperthermia. Hum Cell 7:55-61
    • (1994) Hum Cell , vol.7 , pp. 55-61
    • Saito, T.1    Kato, H.2    Saito, M.3
  • 128
    • 0028021566 scopus 로고
    • The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells
    • Saito Y, Vandenheede JR, Cohen P (1994b) The mechanism by which epidermal growth factor inhibits glycogen synthase kinase 3 in A431 cells. Biochem J 303(Pt 1):27-31
    • (1994) Biochem J , vol.303 , Issue.PART 1 , pp. 27-31
    • Saito, Y.1    Vandenheede, J.R.2    Cohen, P.3
  • 129
    • 0038044650 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signaling
    • Sanchez JF, Sniderhan LF, Williamson AL et al (2003) Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signaling. Mol Cell Biol 23:4649-4662
    • (2003) Mol Cell Biol , vol.23 , pp. 4649-4662
    • Sanchez, J.F.1    Sniderhan, L.F.2    Williamson, A.L.3
  • 130
    • 0029821811 scopus 로고    scopus 로고
    • bcl-2 expression and prognosis in squamous-cell carcinomas of the esophagus
    • Sarbia M, Bittinger F, Porschen R et al (1996) bcl-2 expression and prognosis in squamous-cell carcinomas of the esophagus. Int J Cancer 69:324-328
    • (1996) Int J Cancer , vol.69 , pp. 324-328
    • Sarbia, M.1    Bittinger, F.2    Porschen, R.3
  • 131
    • 0030905961 scopus 로고    scopus 로고
    • Basaloid squamous cell carcinoma of the esophagus: Diagnosis and prognosis
    • Sarbia M, Verreet P, Bittinger F et al (1997) Basaloid squamous cell carcinoma of the esophagus: diagnosis and prognosis. Cancer 79:1871-1878
    • (1997) Cancer , vol.79 , pp. 1871-1878
    • Sarbia, M.1    Verreet, P.2    Bittinger, F.3
  • 132
    • 67349142343 scopus 로고    scopus 로고
    • Recent advances in oral oncology 2008; squamous cell carcinoma imaging, treatment, prognostication and treatment outcomes
    • Scully C, Bagan JV (2009) Recent advances in oral oncology 2008; squamous cell carcinoma imaging, treatment, prognostication and treatment outcomes. Oral Oncol 45:e25-e30
    • (2009) Oral Oncol , vol.45
    • Scully, C.1    Bagan, J.V.2
  • 133
    • 23044444841 scopus 로고    scopus 로고
    • Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation
    • Shakoori A, Ougolkov A, Yu ZW et al (2005) Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation. Biochem Biophys Res Commun 334:1365-1373
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 1365-1373
    • Shakoori, A.1    Ougolkov, A.2    Yu, Z.W.3
  • 134
    • 0032746343 scopus 로고    scopus 로고
    • Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells
    • Shaw M, Cohen P (1999) Role of protein kinase B and the MAP kinase cascade in mediating the EGF-dependent inhibition of glycogen synthase kinase 3 in Swiss 3T3 cells. FEBS Lett 461:120-124
    • (1999) FEBS Lett , vol.461 , pp. 120-124
    • Shaw, M.1    Cohen, P.2
  • 135
    • 2242456802 scopus 로고    scopus 로고
    • Protein kinase A negatively modulates the nuclear accumulation of NF-ATc1 by priming for subsequent phosphorylation by glycogen synthase kinase-3
    • Sheridan CM, Heist EK, Beals CR et al (2002) Protein kinase A negatively modulates the nuclear accumulation of NF-ATc1 by priming for subsequent phosphorylation by glycogen synthase kinase-3. J Biol Chem 277:48664-48676
    • (2002) J Biol Chem , vol.277 , pp. 48664-48676
    • Sheridan, C.M.1    Heist, E.K.2    Beals, C.R.3
  • 136
    • 84866396210 scopus 로고    scopus 로고
    • Let-7 expression is a significant determinant of response to chemotherapy through the regulation of IL-6/STAT3 pathway in esophageal squamous cell carcinoma
    • Sugimura K, Miyata H, Tanaka K et al (2012) Let-7 expression is a significant determinant of response to chemotherapy through the regulation of IL-6/STAT3 pathway in esophageal squamous cell carcinoma. Clin Cancer Res 18:5144-5153
    • (2012) Clin Cancer Res , vol.18 , pp. 5144-5153
    • Sugimura, K.1    Miyata, H.2    Tanaka, K.3
  • 137
    • 67349268981 scopus 로고    scopus 로고
    • Zebularine suppresses the apoptotic potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human oral squamous cell carcinoma cells
    • Suzuki M, Shinohara F, Endo M et al (2009) Zebularine suppresses the apoptotic potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human oral squamous cell carcinoma cells. Cancer Chemother Pharmacol 64:223-232
    • (2009) Cancer Chemother Pharmacol , vol.64 , pp. 223-232
    • Suzuki, M.1    Shinohara, F.2    Endo, M.3
  • 138
    • 84857831583 scopus 로고    scopus 로고
    • DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells
    • Taira N, Mimoto R, Kurata M et al (2012) DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells. J Clin Invest 122:859-872
    • (2012) J Clin Invest , vol.122 , pp. 859-872
    • Taira, N.1    Mimoto, R.2    Kurata, M.3
  • 139
    • 25444519182 scopus 로고    scopus 로고
    • Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells
    • Tan J, Zhuang L, Leong HS et al (2005) Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells. Cancer Res 65:9012-9020
    • (2005) Cancer Res , vol.65 , pp. 9012-9020
    • Tan, J.1    Zhuang, L.2    Leong, H.S.3
  • 140
    • 0032821768 scopus 로고    scopus 로고
    • A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin
    • Thomas GM, Frame S, Goedert M et al (1999) A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin. FEBS Lett 458:247-251
    • (1999) FEBS Lett , vol.458 , pp. 247-251
    • Thomas, G.M.1    Frame, S.2    Goedert, M.3
  • 141
    • 79951760847 scopus 로고    scopus 로고
    • The relationship between p27(kip1) expression and the change of radiosensitivity of esophageal carcinoma cells
    • Tong Q, Zhang W, Jin S et al (2011) The relationship between p27(kip1) expression and the change of radiosensitivity of esophageal carcinoma cells. Scand J Gastroenterol 46:173-176
    • (2011) Scand J Gastroenterol , vol.46 , pp. 173-176
    • Tong, Q.1    Zhang, W.2    Jin, S.3
  • 142
    • 18544367202 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha in Barrett's oesophagus: A potential novel mechanism of action
    • Tselepis C, Perry I, Dawson C et al (2002) Tumour necrosis factor-alpha in Barrett's oesophagus: a potential novel mechanism of action. Oncogene 21:6071-6081
    • (2002) Oncogene , vol.21 , pp. 6071-6081
    • Tselepis, C.1    Perry, I.2    Dawson, C.3
  • 143
    • 1242293661 scopus 로고    scopus 로고
    • Serum interleukin-12 and interleukin-18 levels as a tumor marker in patients with esophageal carcinoma
    • Tsuboi K, Miyazaki T, Nakajima M et al (2004) Serum interleukin-12 and interleukin-18 levels as a tumor marker in patients with esophageal carcinoma. Cancer Lett 205:207-214
    • (2004) Cancer Lett , vol.205 , pp. 207-214
    • Tsuboi, K.1    Miyazaki, T.2    Nakajima, M.3
  • 144
    • 5444237088 scopus 로고    scopus 로고
    • STAT proteins as novel targets for cancer drug discovery
    • Turkson J (2004) STAT proteins as novel targets for cancer drug discovery. Expert Opin Ther Targets 8:409-422
    • (2004) Expert Opin Ther Targets , vol.8 , pp. 409-422
    • Turkson, J.1
  • 145
    • 33750454439 scopus 로고    scopus 로고
    • Predictive and prognostic molecular markers in outcome of esophageal cancer
    • Vallbohmer D, Lenz HJ (2006) Predictive and prognostic molecular markers in outcome of esophageal cancer. Dis Esophagus 19:425-432
    • (2006) Dis Esophagus , vol.19 , pp. 425-432
    • Vallbohmer, D.1    Lenz, H.J.2
  • 146
    • 0037208680 scopus 로고    scopus 로고
    • Immune responses and prediction of major infection in patients undergoing transhiatal or transthoracic esophagectomy for cancer
    • van Sandick JW, Gisbertz SS, ten Berge IJ et al (2003) Immune responses and prediction of major infection in patients undergoing transhiatal or transthoracic esophagectomy for cancer. Ann Surg 237:35-43
    • (2003) Ann Surg , vol.237 , pp. 35-43
    • Van Sandick, J.W.1    Gisbertz, S.S.2    Ten Berge, I.J.3
  • 147
    • 10744222577 scopus 로고    scopus 로고
    • Down-regulation of beta catenin inhibits the growth of esophageal carcinoma cells
    • Veeramachaneni NK, Kubokura H, Lin L et al (2004) Down-regulation of beta catenin inhibits the growth of esophageal carcinoma cells. J Thorac Cardiovasc Surg 127:92-98
    • (2004) J Thorac Cardiovasc Surg , vol.127 , pp. 92-98
    • Veeramachaneni, N.K.1    Kubokura, H.2    Lin, L.3
  • 148
    • 82555191519 scopus 로고    scopus 로고
    • Overexpression of p75(NTR) increases survival of breast cancer cells through p21(waf1)
    • Verbeke S, Meignan S, Lagadec C et al (2010) Overexpression of p75(NTR) increases survival of breast cancer cells through p21(waf1). Cell Signal 22:1864-1873
    • (2010) Cell Signal , vol.22 , pp. 1864-1873
    • Verbeke, S.1    Meignan, S.2    Lagadec, C.3
  • 149
    • 36849058762 scopus 로고    scopus 로고
    • Deciphering AP-1 function in tumorigenesis: Fra-ternizing on target promoters
    • Verde P, Casalino L, Talotta F et al (2007) Deciphering AP-1 function in tumorigenesis: fra-ternizing on target promoters. Cell Cycle 6:2633-2639
    • (2007) Cell Cycle , vol.6 , pp. 2633-2639
    • Verde, P.1    Casalino, L.2    Talotta, F.3
  • 150
    • 0028897739 scopus 로고
    • Inhibition of angiogenesis in vivo by interleukin 12
    • Voest EE, Kenyon BM, O'Reilly MS et al (1995) Inhibition of angiogenesis in vivo by interleukin 12. J Natl Cancer Inst 87:581-586
    • (1995) J Natl Cancer Inst , vol.87 , pp. 581-586
    • Voest, E.E.1    Kenyon, B.M.2    O'Reilly, M.S.3
  • 151
    • 0037418208 scopus 로고    scopus 로고
    • IL-1 is required for tumor invasiveness and angiogenesis
    • Voronov E, Shouval DS, Krelin Y et al (2003) IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci USA 100:2645-2650
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2645-2650
    • Voronov, E.1    Shouval, D.S.2    Krelin, Y.3
  • 152
    • 0035205974 scopus 로고    scopus 로고
    • Role of TNF family ligands in antitumor activity of natural killer cells
    • Vujanovic NL (2001) Role of TNF family ligands in antitumor activity of natural killer cells. Int Rev Immunol 20:415-437
    • (2001) Int Rev Immunol , vol.20 , pp. 415-437
    • Vujanovic, N.L.1
  • 153
    • 0029741324 scopus 로고    scopus 로고
    • Overexpression of cyclin D1 and cyclin E in N-nitrosomethylbenzylamine- induced rat esophageal tumorigenesis
    • Wang QS, Sabourin CL, Wang H et al (1996) Overexpression of cyclin D1 and cyclin E in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. Carcinogenesis 17:1583-1588
    • (1996) Carcinogenesis , vol.17 , pp. 1583-1588
    • Wang, Q.S.1    Sabourin, C.L.2    Wang, H.3
  • 154
    • 0000586543 scopus 로고    scopus 로고
    • Apoptosis and its relationship with cell proliferation, p53, Waf1p21, bcl-2 and c-Myc in esophageal carcinogenesis studied with a high-risk population in northern China
    • Wang LD, Zhou Q, Wei JP et al (1998) Apoptosis and its relationship with cell proliferation, p53, Waf1p21, bcl-2 and c-Myc in esophageal carcinogenesis studied with a high-risk population in northern China. World J Gastroenterol 4:287-293
    • (1998) World J Gastroenterol , vol.4 , pp. 287-293
    • Wang, L.D.1    Zhou, Q.2    Wei, J.P.3
  • 155
    • 0038729193 scopus 로고    scopus 로고
    • Primary adenocarcinomas of lower esophagus, esophagogastric junction and gastric cardia: In special reference to China
    • Wang LD, Zheng S, Zheng ZY et al (2003) Primary adenocarcinomas of lower esophagus, esophagogastric junction and gastric cardia: in special reference to China. World J Gastroenterol 9:1156-1164
    • (2003) World J Gastroenterol , vol.9 , pp. 1156-1164
    • Wang, L.D.1    Zheng, S.2    Zheng, Z.Y.3
  • 156
    • 58149198796 scopus 로고    scopus 로고
    • IFN-beta production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-beta
    • Wang H, Garcia CA, Rehani K et al (2008) IFN-beta production by TLR4-stimulated innate immune cells is negatively regulated by GSK3-beta. J Immunol 181:6797-6802
    • (2008) J Immunol , vol.181 , pp. 6797-6802
    • Wang, H.1    Garcia, C.A.2    Rehani, K.3
  • 157
    • 67650495415 scopus 로고    scopus 로고
    • IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
    • Wang L, Yi T, Kortylewski M et al (2009) IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J Exp Med 206:1457-1464
    • (2009) J Exp Med , vol.206 , pp. 1457-1464
    • Wang, L.1    Yi, T.2    Kortylewski, M.3
  • 158
    • 79251589064 scopus 로고    scopus 로고
    • The role of glycogen synthase kinase 3 in regulating IFN-beta-mediated IL-10 production
    • Wang H, Brown J, Garcia CA et al (2011a) The role of glycogen synthase kinase 3 in regulating IFN-beta-mediated IL-10 production. J Immunol 186:675-684
    • (2011) J Immunol , vol.186 , pp. 675-684
    • Wang, H.1    Brown, J.2    Garcia, C.A.3
  • 159
    • 79955548609 scopus 로고    scopus 로고
    • Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-beta-signaling pathways regulates the innate inflammatory response
    • Wang H, Brown J, Gu Z et al (2011b) Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-beta-signaling pathways regulates the innate inflammatory response. J Immunol 186:5217-5226
    • (2011) J Immunol , vol.186 , pp. 5217-5226
    • Wang, H.1    Brown, J.2    Gu, Z.3
  • 160
    • 78651075836 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: A point of convergence for the host inflammatory response
    • Wang H, Brown J, Martin M (2011c) Glycogen synthase kinase 3: a point of convergence for the host inflammatory response. Cytokine 53:130-140
    • (2011) Cytokine , vol.53 , pp. 130-140
    • Wang, H.1    Brown, J.2    Martin, M.3
  • 161
    • 78651090290 scopus 로고    scopus 로고
    • Defective anchoring of JNK1 in the cytoplasm by MKK7 in Jurkat cells is associated with resistance to Fas-mediated apoptosis
    • Wang J, Tang R, Lv M et al (2011d) Defective anchoring of JNK1 in the cytoplasm by MKK7 in Jurkat cells is associated with resistance to Fas-mediated apoptosis. Mol Biol Cell 22:117-127
    • (2011) Mol Biol Cell , vol.22 , pp. 117-127
    • Wang, J.1    Tang, R.2    Lv, M.3
  • 162
    • 0442274617 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53
    • Watcharasit P, Bijur GN, Song L et al (2003) Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53. J Biol Chem 278:48872-48879
    • (2003) J Biol Chem , vol.278 , pp. 48872-48879
    • Watcharasit, P.1    Bijur, G.N.2    Song, L.3
  • 163
    • 22244476115 scopus 로고    scopus 로고
    • The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
    • Wei W, Jin J, Schlisio S et al (2005) The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase. Cancer Cell 8:25-33
    • (2005) Cancer Cell , vol.8 , pp. 25-33
    • Wei, W.1    Jin, J.2    Schlisio, S.3
  • 164
    • 17544374351 scopus 로고    scopus 로고
    • T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3
    • Welsh GI, Miyamoto S, Price NT et al (1996) T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3. J Biol Chem 271:11410-11413
    • (1996) J Biol Chem , vol.271 , pp. 11410-11413
    • Welsh, G.I.1    Miyamoto, S.2    Price, N.T.3
  • 165
    • 0034742512 scopus 로고    scopus 로고
    • IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas
    • Wolf JS, Chen Z, Dong G et al (2001) IL (interleukin)-1alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. Clin Cancer Res 7:1812-1820
    • (2001) Clin Cancer Res , vol.7 , pp. 1812-1820
    • Wolf, J.S.1    Chen, Z.2    Dong, G.3
  • 166
    • 33845951877 scopus 로고    scopus 로고
    • TcR and TcR-CD28 engagement of protein kinase B (PKB/AKT) and glycogen synthase kinase-3 (GSK-3) operates independently of guanine nucleotide exchange factor VAV-1
    • Wood JE, Schneider H, Rudd CE (2006) TcR and TcR-CD28 engagement of protein kinase B (PKB/AKT) and glycogen synthase kinase-3 (GSK-3) operates independently of guanine nucleotide exchange factor VAV-1. J Biol Chem 281:32385-32394
    • (2006) J Biol Chem , vol.281 , pp. 32385-32394
    • Wood, J.E.1    Schneider, H.2    Rudd, C.E.3
  • 167
    • 0025286104 scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-3/factor A
    • Woodgett JR (1990) Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J 9:2431-2438
    • (1990) EMBO J , vol.9 , pp. 2431-2438
    • Woodgett, J.R.1
  • 168
    • 0021174730 scopus 로고
    • Multisite phosphorylation of glycogen synthase. Molecular basis for the substrate specificity of glycogen synthase kinase-3 and casein kinase-II (glycogen synthase kinase-5)
    • Woodgett JR, Cohen P (1984) Multisite phosphorylation of glycogen synthase. Molecular basis for the substrate specificity of glycogen synthase kinase-3 and casein kinase-II (glycogen synthase kinase-5). Biochim Biophys Acta 788:339-347
    • (1984) Biochim Biophys Acta , vol.788 , pp. 339-347
    • Woodgett, J.R.1    Cohen, P.2
  • 169
    • 0344874662 scopus 로고    scopus 로고
    • Inhibition of adenovirus-mediated p27kip1 gene on growth of esophageal carcinoma cell strain
    • Wu QM, Yu JP, Tong Q et al (2003) Inhibition of adenovirus-mediated p27kip1 gene on growth of esophageal carcinoma cell strain. World J Gastroenterol 9:2404-2408
    • (2003) World J Gastroenterol , vol.9 , pp. 2404-2408
    • Wu, Q.M.1    Yu, J.P.2    Tong, Q.3
  • 170
    • 2942614705 scopus 로고    scopus 로고
    • Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
    • Yada M, Hatakeyama S, Kamura T et al (2004) Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J 23:2116-2125
    • (2004) EMBO J , vol.23 , pp. 2116-2125
    • Yada, M.1    Hatakeyama, S.2    Kamura, T.3
  • 171
    • 53249127054 scopus 로고    scopus 로고
    • beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma
    • Yan S, Zhou C, Zhang W et al (2008) beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma. Cancer Lett 271:85-97
    • (2008) Cancer Lett , vol.271 , pp. 85-97
    • Yan, S.1    Zhou, C.2    Zhang, W.3
  • 172
    • 0029555301 scopus 로고
    • Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
    • Yao Z, Fanslow WC, Seldin MF et al (1995) Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3:811-821
    • (1995) Immunity , vol.3 , pp. 811-821
    • Yao, Z.1    Fanslow, W.C.2    Seldin, M.F.3
  • 173
    • 0031009807 scopus 로고    scopus 로고
    • Involvement of interleukin- 8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis
    • Yoshida S, Ono M, Shono T et al (1997) Involvement of interleukin- 8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis. Mol Cell Biol 17:4015-4023
    • (1997) Mol Cell Biol , vol.17 , pp. 4015-4023
    • Yoshida, S.1    Ono, M.2    Shono, T.3
  • 174
    • 59549100166 scopus 로고    scopus 로고
    • Esophageal adenocarcinoma arising in Barrett esophagus
    • Zhang HY, Spechler SJ, Souza RF (2009) Esophageal adenocarcinoma arising in Barrett esophagus. Cancer Lett 275:170-177
    • (2009) Cancer Lett , vol.275 , pp. 170-177
    • Zhang, H.Y.1    Spechler, S.J.2    Souza, R.F.3
  • 175
    • 0036677099 scopus 로고    scopus 로고
    • Expression and significance of beta-catenin in esophageal carcinoma
    • Zhou XB, Lu N, Zhang W et al (2002) Expression and significance of beta-catenin in esophageal carcinoma. Ai Zheng 21:877-880
    • (2002) Ai Zheng , vol.21 , pp. 877-880
    • Zhou, X.B.1    Lu, N.2    Zhang, W.3
  • 176
    • 55049086241 scopus 로고    scopus 로고
    • Growth control of multiple myeloma cells through inhibition of glycogen synthase kinase-3
    • Zhou Y, Uddin S, Zimmerman T et al (2008) Growth control of multiple myeloma cells through inhibition of glycogen synthase kinase-3. Leuk Lymphoma 49:1945-1953
    • (2008) Leuk Lymphoma , vol.49 , pp. 1945-1953
    • Zhou, Y.1    Uddin, S.2    Zimmerman, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.