Type I collagen and divalent cation shifts disrupt cell-cell adhesion, increase migration, and decrease PTHrP, IL-6, and IL-8 expression in pancreatic cancer cells

International Journal of Gastrointestinal Cancer

Volumn 36, Issue 3, 2005, Pages 131-146

  Grzesiak, John J ^a   Smith, Kathy C ^b   Chalberg, Cheryl ^b   Burton, Douglas W ^b   Deftos, Leonard J ^b   Bouvet, Michael ^a,c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

catenin; E cadherin; Fibronectin; Glycogen synthase kinase (GSK3); Integrins; Protein kinase B (PKB Akt)

Indexed keywords

BETA CATENIN; COLLAGEN TYPE 1; CYTOKINE; DIVALENT CATION; FIBRONECTIN; GLYCOGEN SYNTHASE KINASE; INTEGRIN; INTERLEUKIN 6; INTERLEUKIN 8; PARATHYROID HORMONE RELATED PROTEIN; PROTEIN KINASE B; UVOMORULIN; VERY LATE ACTIVATION ANTIGEN 2;

ARTICLE; CANCER CELL; CELL ADHESION; CELL MIGRATION; CYTOARCHITECTURE; EFFECTOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; GENE DISRUPTION; GENE MUTATION; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOCARCINOMA; CADHERINS; CALCIUM; CELL ADHESION; COLLAGEN TYPE I; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTEGRINS; INTERLEUKIN-6; INTERLEUKIN-8; MAGNESIUM; MICROSCOPY, FLUORESCENCE; PANCREATIC NEOPLASMS; PARATHYROID HORMONE-RELATED PROTEIN; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 33745683734     PISSN: 01694197     EISSN: None     Source Type: Journal    
DOI: 10.1385/IJGC:36:3:131     Document Type: Article

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