p53, p21(Waf1/Cip1) and cyclin D1 protein expression and prognosis in esophageal cancer

Diseases of the Esophagus

Volumn 12, Issue 2, 1999, Pages 116-119

  Kuwahara, M ^a   Hirai, T ^a   Yoshida, K ^a   Yamashita, Y ^a   Hihara, J ^a   Inoue, H ^a   Toge, T ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CISPLATIN; CYCLIN D1; PROTEIN P21; PROTEIN P53;

ARTICLE; CANCER ADJUVANT THERAPY; CANCER STAGING; CANCER SURVIVAL; ESOPHAGUS CANCER; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; ENZYME INHIBITORS; ESOPHAGEAL NEOPLASMS; FEMALE; HUMANS; MALE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SURVIVAL RATE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0032770368     PISSN: 11208694     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1442-2050.1999.00034.x     Document Type: Article

References (9)

1. Japanese Society for Esophageal Diseases. Guidelines for the clinical and pathological studies on carcinoma of the esophagus, 8th edn. Tokyo: Kanehara Shuppan, 1992.
2. Levine A J, Momand J, Finlay C A. The p53 tumor suppressor gene. Nature 1991; 351: 453-456.
3. Bosari S, Viale G. The clinical significance of p53 aberrations in human tumors. Virchow Arch 1995; 427: 229-241.
4. Greenblatt M S, Bennett W P, Hollstein M, Harris C C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994; 54: 4855-4878.
5. Coggi G, Bosari S, Roncalli M, et al. p53 protein accumulation and p53 gene mutation in Esophageal carcinoma - a molecular and immunohistochemical study with clinicopathologic correlations. Cancer 1997; 79: 425-432.
6. Ogawa M, Maeda K, Onoda N, et al. Immunohistochemical study of p21 expression in gastric carcinoma. Gan To Kagaku Ryoho 1997; 24: 292-295.
7. Aoyagi K, Koufuji K, Kodama I, et al. The significance of p21 expression in gastric cancer. Gan To Kagaku Ryoho 1997; 24: 285-291.
8. Hickey K, Grehan D, Reid I M, O'Briain S, Walsh T N, Hennesy T P J. Expression of epidermal growth factor receptor and proliferating cell nuclear antigen predicts response of esophageal squamous cell carcinoma to chemoradiotherapy. Cancer 1994; 74: 1693-1698.
9. Gaffey M J, Frierson H F Jr, Williams M E. Chromosome 11q13, c-erbB-2, and c-myc amplification in invasive breast carcinoma: Clinicopathologic correlations. Mod Pathol 1993; 6: 654-659.