Calpain 2 regulates Akt-FoxO-p27Kip1 protein signaling pathway in mammary carcinoma

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15458-15465

  Ho, Wai Chi ^a   Pikor, Larissa ^a   Gao, Yan ^a   Elliott, Bruce E ^a   Greer, Peter A ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ANALYSIS; BREAST TUMOR CELLS; CALPAINS; CATALYTIC SUBUNITS; COLONY FORMATION; DE-REPRESSION; IN-VITRO; IN-VIVO; ISOFORMS; KEY REGULATORS; MAMMARY CARCINOMA; MAMMARY CARCINOMA CELL; MIGRATION RATES; MITOGENESIS; NUCLEAR LOCALIZATION; PROLIFERATION RATE; PROTEIN PHOSPHATASE 2A; PROTEIN SIGNALING; REDUCED GROWTH RATE; SIGNALING CASCADES; SOFT AGAR; TARGET GENES; THERAPEUTIC BENEFITS; TRANSCRIPTIONAL TARGETS; TUMOR SUPPRESSORS; TUMORIGENESIS;

CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; GENES; GROWTH KINETICS;

TUMORS;

CALPAIN 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER CELL; CARCINOGENICITY; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME INHIBITION; METASTASIS; MITOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BLOTTING, WESTERN; CALPAIN; CELL LINE, TUMOR; CELL MOVEMENT; CELL NUCLEUS; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOPLASM; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; LUNG NEOPLASMS; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR BURDEN;

EID: 84860849870     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.349308     Document Type: Article

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