Angiotensin II causes imbalance between pro- and anti-inflammatory cytokines by modulating GSK-3β in neuronal culture

British Journal of Pharmacology

Volumn 169, Issue 4, 2013, Pages 860-874

  Agarwal, Deepmala ^a   Dange, Rahul B ^a   Raizada, Mohan K ^b   Francis, Joseph ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

angiotensin; anti inflammatory cytokines; brain; CATH.a; cytokines; GSK 3; hypertension; PVN

Indexed keywords

ANGIOTENSIN II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; SERINE; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR ALPHA; TYROSINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE;

ANGIOTENSIN II; ANIMALS; CHOLINERGIC NEURONS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOKINES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE SILENCING; GLYCOGEN SYNTHASE KINASE 3; HYBRIDOMAS; KINETICS; LOCUS COERULEUS; MICE; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; NF-KAPPA B; PHOSPHORYLATION; PILOT PROJECTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, SMALL INTERFERING;

EID: 84878280158     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12177     Document Type: Article

References (57)

1. Agarwal D, Haque M, Sriramula S, Mariappan N, Pariaut R, Francis J, (2009). Role of proinflammatory cytokines and redox homeostasis in exercise-induced delayed progression of hypertension in spontaneously hypertensive rats. Hypertension 54: 1393-1400.
2. Agarwal D, Welsch MA, Keller JN, Francis J, (2011). Chronic exercise modulates RAS components and improves balance between pro- and anti-inflammatory cytokines in the brain of SHR. Basic Res Cardiol 106: 1069-1085.
3. Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, et al. (1996). Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15: 6541-6551.
4. Ali A, Hoeflich KP, Woodgett JR, (2001). Glycogen synthase kinase-3: properties, functions, and regulation. Chem Rev 101: 2527-2540.
5. Avni D, Ernst O, Philosoph A, Zor T, (2010). Role of CREB in modulation of TNFalpha and IL-10 expression in LPS-stimulated RAW264.7 macrophages. Mol Immunol 47: 1396-1403.
6. Beurel E, Jope RS, (2009). Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain. J Neuroinflammation 6: 9.
7. Bradford MM, (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
8. Cardinale JP, Sriramula S, Mariappan N, Agarwal D, Francis J, (2012). Angiotensin II-Induced Hypertension Is Modulated by nuclear factor-kappaB in the paraventricular nucleus. Hypertension 59: 113-121.
9. Chae CU, Lee RT, Rifai N, Ridker PM, (2001). Blood pressure and inflammation in apparently healthy men. Hypertension 38: 399-403.
10. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH, (1993). Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365: 855-859.
11. Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P, (1994). The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf. Biochem J 303 (Pt 1): 21-26.
12. Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA, (1995). Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378: 785-789.
13. Doble BW, Woodgett JR, (2003). GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci 116 (Pt 7): 1175-1186.
14. Dorffel Y, Latsch C, Stuhlmuller B, Schreiber S, Scholze S, Burmester GR, et al. (1999). Preactivated peripheral blood monocytes in patients with essential hypertension. Hypertension 34: 113-117.
15. Embi N, Rylatt DB, Cohen P, (1980). Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 107: 519-527.
16. Forde JE, Dale TC, (2007). Glycogen synthase kinase 3: a key regulator of cellular fate. Cell Mol Life Sci 64: 1930-1944.
17. Frame S, Cohen P, (2001). GSK3 takes centre stage more than 20 years after its discovery. Biochem J 359 (Pt 1): 1-16.
18. Gao L, Li Y, Schultz HD, Wang WZ, Wang W, Finch M, et al. (2010). Downregulated Kv4.3 expression in the RVLM as a potential mechanism for sympathoexcitation in rats with chronic heart failure. Am J Physiol Heart Circ Physiol 298: H945-H955.
19. Ghosh S, Karin M, (2002). Missing pieces in the NF-kappaB puzzle. Cell 109 (Suppl.): S81-S96.
20. Grimes CA, Jope RS, (2001a). CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium. J Neurochem 78: 1219-1232.
21. Grimes CA, Jope RS, (2001b). The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol 65: 391-426.
22. Guggilam A, Cardinale JP, Mariappan N, Sriramula S, Haque M, Francis J, (2011). Central TNF inhibition results in attenuated neurohumoral excitation in heart failure: a role for superoxide and nitric oxide. Basic Res Cardiol 106: 273-286.
23. Haack KK, Engler CW, Papoutsi E, Pipinos II, Patel KP, Zucker IH, (2012). Parallel changes in neuronal AT1R and GRK5 expression following exercise training in heart failure. Hypertension 60: 354-361.
24. Hughes K, Nikolakaki E, Plyte SE, Totty NF, Woodgett JR, (1993). Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation. EMBO J 12: 803-808.
25. Javadov S, Rajapurohitam V, Kilic A, Zeidan A, Choi A, Karmazyn M, (2009). Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3beta-dependent attenuation of mitochondrial dysfunction. J Mol Cell Cardiol 46: 998-1007.
26. Kang YM, Ma Y, Zheng JP, Elks C, Sriramula S, Yang ZM, et al. (2009). Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension. Cardiovasc Res 82: 503-512.
27. Kang YM, Gao F, Li HH, Cardinale JP, Elks C, Zang WJ, et al. (2011). NF-kappaB in the paraventricular nucleus modulates neurotransmitters and contributes to sympathoexcitation in heart failure. Basic Res Cardiol 106: 1087-1097.
28. Leroy K, Brion JP, (1999). Developmental expression and localization of glycogen synthase kinase-3beta in rat brain. J Chem Neuroanat 16: 279-293.
29. Li Y, Hou LX, Aktiv A, Dahlstrom A, (2007). Studies of the central nervous system-derived CAD cell line, a suitable model for intraneuronal transport studies? J Neurosci Res 85: 2601-2609.
30. Liu D, Gao L, Roy SK, Cornish KG, Zucker IH, (2006). Neuronal angiotensin II type 1 receptor upregulation in heart failure: activation of activator protein 1 and Jun N-terminal kinase. Circ Res 99: 1004-1011.
31. MacAulay K, Woodgett JR, (2008). Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of type 2 diabetes. Expert Opin Ther Targets 12: 1265-1274.
32. Martin M, Rehani K, Jope RS, Michalek SM, (2005). Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat Immunol 6: 777-784.
33. Mitra AK, Gao L, Zucker IH, (2010). Angiotensin II-induced upregulation of AT(1) receptor expression: sequential activation of NF-kappaB and Elk-1 in neurons. Am J Physiol Cell Physiol 299: C561-C569.
34. Okada H, Inoue T, Kikuta T, Watanabe Y, Kanno Y, Ban S, et al. (2006). A possible anti-inflammatory role of angiotensin II type 2 receptor in immune-mediated glomerulonephritis during type 1 receptor blockade. Am J Pathol 169: 1577-1589.
35. Peeters AC, Netea MG, Janssen MC, Kullberg BJ, Van der Meer JW, Thien T, (2001). Pro-inflammatory cytokines in patients with essential hypertension. Eur J Clin Invest 31: 31-36.
36. Plyte SE, Hughes K, Nikolakaki E, Pulverer BJ, Woodgett JR, (1992). Glycogen synthase kinase-3: functions in oncogenesis and development. Biochim Biophys Acta 1114: 147-162.
37. Reber L, Vermeulen L, Haegeman G, Frossard N, (2009). Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation. Plos One 4: e4393.
38. Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, et al. (2011). Heart disease and stroke statistics-2011 update: a report from the American Heart Association. Circulation 123: e18-e209.
39. Rylatt DB, Aitken A, Bilham T, Condon GD, Embi N, Cohen P, (1980). Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase. Eur J Biochem 107: 529-537.
40. Shenkar R, Yum HK, Arcaroli J, Kupfner J, Abraham E, (2001). Interactions between CBP, NF-kappaB, and CREB in the lungs after hemorrhage and endotoxemia. Am J Physiol Lung Cell Mol Physiol 281: L418-L426.
41. Shi P, Raizada MK, Sumners C, (2010). Brain cytokines as neuromodulators in cardiovascular control. Clin Exp Pharmacol Physiol 37: e52-e57.
42. Stefano L, Al Sarraj J, Rossler OG, Vinson C, Thiel G, (2006). Up-regulation of tyrosine hydroxylase gene transcription by tetradecanoylphorbol acetate is mediated by the transcription factors Ets-like protein-1 (Elk-1) and Egr-1. J Neurochem 97: 92-104.
43. Steinbrecher KA, Wilson W, 3rd, Cogswell PC, Baldwin AS, (2005). Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription. Mol Cell Biol 25: 8444-8455.
44. Sun C, Sumners C, Raizada MK, (2002). Chronotropic action of angiotensin II in neurons via protein kinase C and CaMKII. Hypertension 39 (2 Pt 2): 562-566.
45. Sun C, Du J, Raizada MK, Sumners C, (2003). Modulation of delayed rectifier potassium current by angiotensin II in CATH.a cells. Biochem Biophys Res Commun 310: 710-714.
46. Swanson DJ, Zellmer E, Lewis EJ, (1998). AP1 proteins mediate the cAMP response of the dopamine beta-hydroxylase gene. J Biol Chem 273: 24065-24074.
47. Takahashi N, Tetsuka T, Uranishi H, Okamoto T, (2002). Inhibition of the NF-kappaB transcriptional activity by protein kinase A. Eur J Biochem 269: 4559-4565.
48. Tateishi A, Matsushita M, Asai T, Masuda Z, Kuriyama M, Kanki K, et al. (2010). Effect of inhibition of glycogen synthase kinase-3 on cardiac hypertrophy during acute pressure overload. Gen Thorac Cardiovasc Surg 58: 265-270.
49. Vines A, Cahoon S, Goldberg I, Saxena U, Pillarisetti S, (2006). Novel anti-inflammatory role for glycogen synthase kinase-3beta in the inhibition of tumor necrosis factor-alpha- and interleukin-1beta-induced inflammatory gene expression. J Biol Chem 281: 16985-16990.
50. Wei SG, Yu Y, Zhang ZH, Felder RB, (2009). Angiotensin II upregulates hypothalamic AT1 receptor expression in rats via the mitogen-activated protein kinase pathway. Am J Physiol Heart Circ Physiol 296: H1425-H1433.
51. Wolf G, Wenzel UO, (2004). Angiotensin II and cell cycle regulation. Hypertension 43: 693-698.
52. Woodgett JR, (2001). Judging a protein by more than its name: GSK-3. Sci STKE 2001: re12.
53. Woodgett JR, Cohen P, (1984). Multisite phosphorylation of glycogen synthase. Molecular basis for the substrate specificity of glycogen synthase kinase-3 and casein kinase-II (glycogen synthase kinase-5). Biochim Biophys Acta 788: 339-347.
54. Xia H, Suda S, Bindom S, Feng Y, Gurley SB, Seth D, et al. (2011). ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function. PLoS ONE 6: e22682.
55. Yang J, Jiang H, Chen SS, Chen J, Xu SK, Li WQ, et al. (2010). CBP knockdown inhibits angiotensin II-induced vascular smooth muscle cells proliferation through downregulating NF-kB transcriptional activity. Mol Cell Biochem 340: 55-62.
56. Zhang ZH, Yu Y, Wei SG, Felder RB, (2012). Aldosterone-induced brain MAPK signaling and sympathetic excitation are angiotensin II type-1 receptor dependent. Am J Physiol Heart Circ Physiol 302: H742-H751.
57. Zimmerman MC, Lazartigues E, Sharma RV, Davisson RL, (2004). Hypertension caused by angiotensin II infusion involves increased superoxide production in the central nervous system. Circ Res 95: 210-216.