Cationic phosphorus-containing dendrimers reduce prion replication both in cell culture and in mice infected with scrapie

Journal of General Virology

Volumn 85, Issue 6, 2004, Pages 1791-1799

  Solassol, Jérôme ^a   Crozet, Carole ^a   Perrier, Véronique ^a   Leclaire, Julien ^b   Béranger, Florence ^a   Caminade, Anne Marie ^b   Meunier, Bernard ^b   Dormont, Dominique ^c   Majoral, Jean Pierre ^b   Lehmann, Sylvain ^a,d  

^a CNRS   (France)

^b LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^c INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^d HÔPITAL SAINT ELOI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; DENDRIMER; PHOSPHORUS; PRION PROTEIN; TERTIARY AMINE; ANTIINFECTIVE AGENT;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BIOACCUMULATION; BOVINE SPONGIFORM ENCEPHALOPATHY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; FEMALE; INFECTION PREVENTION; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; SCRAPIE; SPLEEN; VIRUS INFECTIVITY; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DRUG ANTAGONISM; PRION;

MURINAE;

ANIMALS; ANTI-INFECTIVE AGENTS; CELLS, CULTURED; MICE; MICE, INBRED C57BL; PRIONS; PRPSC PROTEINS; SCRAPIE;

EID: 2942672631     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.19726-0     Document Type: Article

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