Poly(amido)amine dendrimers generation 4.0 (PAMAM G4) reduce blood hyperglycaemia and restore impaired blood-brain barrier permeability in streptozotocin diabetes in rats

International Journal of Pharmaceutics

Volumn 436, Issue 1-2, 2012, Pages 508-518

  Karolczak, Kamil ^a   Rozalska, Sylwia ^b   Wieczorek, Marek ^b   Labieniec Watala, Magdalena ^b   Watala, Cezary ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b UNIVERSITY OF LODZ   (Poland)

Author keywords

Blood brain barrier; Experimental diabetes; Non enzymatic glycosylation of proteins; Poly(amido)amine (PAMAM) dendrimers

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ALPHA CYANO 4 HYDROXYCINNAMIC ACID; DENDRIMER; DEXTRAN; EVANS BLUE; FLUORESCEIN; FLUORESCEIN ISOTHIOCYANATE; GLUCOSE; HEMOGLOBIN A1C; PLACEBO; POLY(AMIDO)AMINE DENDRIMER G4; POLYAMIDOAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BODY WEIGHT; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DIABETES MELLITUS; FRONTAL CORTEX; GLUCOSE BLOOD LEVEL; GLYCATION; HIPPOCAMPUS; HYPERGLYCEMIA; MEDULLA OBLONGATA; MOLECULAR WEIGHT; NONHUMAN; PARIETAL CORTEX; PRIORITY JOURNAL; RAT; THALAMUS;

ANIMALS; BLOOD GLUCOSE; BRAIN; COUMARIC ACIDS; DENDRIMERS; DEXTRANS; DIABETES MELLITUS, EXPERIMENTAL; EVANS BLUE; FLUORESCEIN; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HYPERGLYCEMIA; MONOCARBOXYLIC ACID TRANSPORTERS; NYLONS; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; SYMPORTERS;

EID: 84865285581     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.06.033     Document Type: Article

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