Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Francischetti, Ivo M B ^a   Gordon, Emile ^a   Bizzarro, Bruna ^b   Gera, Nidhi ^a   Andrade, Bruno B ^a   Oliveira, Fabiano ^a   Ma, Dongying ^a   Assumpção, Teresa C F ^a   Ribeiro, José M C ^a   Pena, Mirna ^a   Qi, Chen Feng ^a   Diouf, Ababacar ^a   Moretz, Samuel E ^a   Long, Carole A ^a   Ackerman, Hans C ^a   Pierce, Susan K ^a   Sá Nunes, Anderson ^b   Waisberg, Michael ^a,c  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 5 (3,4,5 TRIMETHOXYBENZAMIDO)DECAHYDROISOQUINOLINE; ALPHA PHENYL N TERTIARY BUTYL NITRONE; ANTIOXIDANT; DIETHYLDITHIOCARBAMIC ACID; DIPHENYLIODONIUM SALT; E 4143; EPIGALLOCATECHIN GALLATE; INTERLEUKIN 12P70; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOQUINONE; MITOTEMPO; MONOCYTE CHEMOTACTIC PROTEIN 1; PBN 203995; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SML 0128; TEMPOL; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BLOOD CLOTTING; BRAIN MALARIA; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENDRITIC CELL; DOWN REGULATION; ENDOTHELIUM CELL; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MALARIA FALCIPARUM; MOUSE; NEUROPROTECTION; NONHUMAN; PHAGOCYTE; PLASMODIUM BERGHEI INFECTION; PLASMODIUM FALCIPARUM; PROMYELOCYTIC LEUKEMIA; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RESPIRATORY BURST; SURVIVAL; THROMBOCYTE AGGREGATION; VASCULITIS;

ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CHEMOKINE CCL2; CYCLIC N-OXIDES; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MALARIA, CEREBRAL; MICE; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; SPIN LABELS; THROMBOPLASTIN;

EID: 84896530422     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087140     Document Type: Article

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